KEGG   Carlito syrichta (Philippine tarsier): 103261208
Entry
103261208         CDS       T07836                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
csyr  Carlito syrichta (Philippine tarsier)
Pathway
csyr03420  Nucleotide excision repair
csyr04115  p53 signaling pathway
csyr04120  Ubiquitin mediated proteolysis
csyr05161  Hepatitis B
csyr05169  Epstein-Barr virus infection
csyr05200  Pathways in cancer
csyr05202  Transcriptional misregulation in cancer
csyr05210  Colorectal cancer
csyr05212  Pancreatic cancer
csyr05213  Endometrial cancer
csyr05214  Glioma
csyr05216  Thyroid cancer
csyr05217  Basal cell carcinoma
csyr05218  Melanoma
csyr05220  Chronic myeloid leukemia
csyr05222  Small cell lung cancer
csyr05223  Non-small cell lung cancer
csyr05224  Breast cancer
csyr05225  Hepatocellular carcinoma
csyr05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:csyr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    103261208 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    103261208 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    103261208 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103261208 (DDB2)
   05202 Transcriptional misregulation in cancer
    103261208 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103261208 (DDB2)
   05212 Pancreatic cancer
    103261208 (DDB2)
   05225 Hepatocellular carcinoma
    103261208 (DDB2)
   05226 Gastric cancer
    103261208 (DDB2)
   05214 Glioma
    103261208 (DDB2)
   05216 Thyroid cancer
    103261208 (DDB2)
   05220 Chronic myeloid leukemia
    103261208 (DDB2)
   05217 Basal cell carcinoma
    103261208 (DDB2)
   05218 Melanoma
    103261208 (DDB2)
   05213 Endometrial cancer
    103261208 (DDB2)
   05224 Breast cancer
    103261208 (DDB2)
   05222 Small cell lung cancer
    103261208 (DDB2)
   05223 Non-small cell lung cancer
    103261208 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    103261208 (DDB2)
   05169 Epstein-Barr virus infection
    103261208 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:csyr04121]
    103261208 (DDB2)
   03400 DNA repair and recombination proteins [BR:csyr03400]
    103261208 (DDB2)
Ubiquitin system [BR:csyr04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     103261208 (DDB2)
DNA repair and recombination proteins [BR:csyr03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      103261208 (DDB2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_WDR75_1st Beta-prop_EML_2 WDR55 Beta-prop_WDR90_POC16_2nd Beta-prop_RIG_2nd Beta-prop_EIPR1 EIF3I Beta-prop_WDR19_1st Beta-prop_TEP1_2nd Beta-prop_IFT140_1st ANAPC4_WD40 Beta-prop_CAF1B_HIR1 Beta-prop_TEP1_C Beta-prop_HPS5 WD40_MABP1-WDR62_2nd NBCH_WD40 WD40_RFWD3 Beta-prop_EML PEP5_VPS11_N Beta-prop_Vps41 Beta-prop_WDR35_TULP_N WD_LRWD1
Other DBs
NCBI-GeneID: 103261208
NCBI-ProteinID: XP_008057022
Ensembl: ENSTSYG00000001500
UniProt: A0A1U7TVC6
LinkDB
Position
Unknown
AA seq 427 aa
MAPKKRPETQKTSEIVLRPRNKRSRSPRELEREAKKLCANGSGSSRKCDSDCLWVGLTSL
EIPPLCRNLVRALHQHKLGETAWPSLQQSLQQSFVRSLDTYRIFQKAAPFDRRATSLAWH
PTHPSTVAVGSKGGDVMLWNFGVKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGT
TRLQDFKGNILRVFANSDTCNVWFCSLDVSATSQMVVTGDNVGNVILLNMDGKELWNLRM
HKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGQASFLYSLPHRHPVNAACFSPDG
AQLLTTDQKSEIRVYSTSQWDCPAGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPN
FKSCSPYELRTIDVFDGNSGRMMCQLYDPESSGISSLNEFNPMGDTLASAMGYHVLIWSQ
EEARTRK
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggcgcccaagaagcgcccagaaacccagaagacctccgagattgtgttacgccccagg
aacaagaggagcagaagtccccgggagctggagcgcgaggccaagaagctctgtgcgaat
ggctccggttctagcagaaaatgtgactcagactgcctttgggtggggttgaccagcctg
gagatcccgccactatgccgcaacctcgtcagagctctccaccagcacaagctgggcgag
actgcctggccatcactacagcagagtcttcagcagtcctttgtgcgctctctggatact
taccggatattccaaaaggccgccccctttgacaggagggcaacatccttggcgtggcac
ccaactcaccctagcaccgtggctgtgggttccaaagggggagatgtcatgctctggaac
tttggcgtaaaggacaaacccaccttcattaaagggattggagctggagggagcatcact
gggctgaagtttaaccctctcaataccaaccagttttacgcctcctcaatggagggaaca
actaggctgcaagactttaaaggcaacattctacgagtttttgccaactcagacacctgc
aacgtctggttttgtagcctggatgtgtctgccactagccagatggtggtcacaggagac
aacgtgggcaatgtgatactgctgaacatggacggcaaagagctttggaatctcagaatg
cacaaaaagaaagtgacccatgtggccctgaacccatgctgtgattggttcctggccaca
gcctccgtagatcaaacagtgaaaatctgggacctgcgccaggttagagggcaagccagc
ttcctctactcgctgccgcacaggcatcctgtcaatgcagcttgtttcagtcctgatgga
gcccagctcctgaccactgaccagaagagtgagatccgggtctactccacctcccagtgg
gactgccccgcgggcctgatcccgcaccctcaccgtcacttccagcacctcacgcccatc
aaggcagcctggcatcctcggtacaacctcattgtcgtgggccgatacccagatcctaat
ttcaaaagttgtagcccctatgaattaaggacaatcgatgtgtttgatggaaactcaggg
aggatgatgtgtcagctctacgacccagaatcttctggtatcagttcgctcaatgagttc
aatcccatgggggacacgctggcctctgcaatgggttatcacgttcttatttggagccag
gaggaagctcgaacacggaaatga

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