Carlito syrichta (Philippine tarsier): 103261654 Help Entry 103261654         CDS       T07836                                  Symbol RYR2 Name (RefSeq) ryanodine receptor 2   KO K04962   ryanodine receptor 2 Organism csyr  Carlito syrichta (Philippine tarsier) Pathway csyr04020   Calcium signaling pathway csyr04024   cAMP signaling pathway csyr04260   Cardiac muscle contraction csyr04261   Adrenergic signaling in cardiomyocytes csyr04371   Apelin signaling pathway csyr04713   Circadian entrainment csyr04911   Insulin secretion csyr04921   Oxytocin signaling pathway csyr04972   Pancreatic secretion csyr05020   Prion disease csyr05022   Pathways of neurodegeneration - multiple diseases csyr05410   Hypertrophic cardiomyopathy csyr05412   Arrhythmogenic right ventricular cardiomyopathy csyr05414   Dilated cardiomyopathy csyr05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:csyr00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     103261654 (RYR2)    04020 Calcium signaling pathway     103261654 (RYR2)    04024 cAMP signaling pathway     103261654 (RYR2)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     103261654 (RYR2)    04921 Oxytocin signaling pathway     103261654 (RYR2)   09153 Circulatory system    04260 Cardiac muscle contraction     103261654 (RYR2)    04261 Adrenergic signaling in cardiomyocytes     103261654 (RYR2)   09154 Digestive system    04972 Pancreatic secretion     103261654 (RYR2)   09159 Environmental adaptation    04713 Circadian entrainment     103261654 (RYR2)  09160 Human Diseases   09164 Neurodegenerative disease    05020 Prion disease     103261654 (RYR2)    05022 Pathways of neurodegeneration - multiple diseases     103261654 (RYR2)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     103261654 (RYR2)    05412 Arrhythmogenic right ventricular cardiomyopathy     103261654 (RYR2)    05414 Dilated cardiomyopathy     103261654 (RYR2)    05415 Diabetic cardiomyopathy     103261654 (RYR2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:csyr04040]     103261654 (RYR2)    04990 Domain-containing proteins not elsewhere classified [BR:csyr04990]     103261654 (RYR2) Ion channels [BR:csyr04040]  Voltage-gated cation channels   Ryanodine receptor    103261654 (RYR2) Domain-containing proteins not elsewhere classified [BR:csyr04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    103261654 (RYR2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY MIR Ins145_P3_rec Motif Other DBs NCBI-GeneID:  103261654 NCBI-ProteinID:  XP_008057423 UniProt:  A0A1U7TLZ2 LinkDB All DBs Position Unknown AA seq 3527 aa AA seqDB search MGELLRTVSLDPSVAAPVGKGPQNLDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLES TSNSKNVPPDLSICTFVLEQSLSVRALQEMLANTVEKSEGQVDVEKWKFMMKTAQGGGHR TLLYGHAILLRHSYSGMYLCCLSTSRSSTDKLAFDVGLQEDTTGEACWWTIHPASKQRSE GEKVRVGDDLILVSVSSERYLHLSYGNGSLHVDAAFQQTLWSVAPISSGSEAAQGYLIGG DVLRLLHGHMDECLTVPSGEHGEEQRRTVHYEGGAVSVHARSLWRLETLRVAWSGSHIRW GQPFRLRHVTTGKYLSLMEDKNLLLMDKEKADVKSTAFTFRSSKEKLDVGVRKEIDGMGT SEIKYGDSVCYIQHVDTGLWLTYQSVDVKSVRMGSIQRKAIMHHEGHMDDGINLSRSQHE ESRTARVIRSTVFLFNRFIRGLDALSKKAKASTVDLPIESVSLSLRDLIGYFHPPDEHLE HEDKQNRLRALKNRQNLFQEEGMINLVLECIDRLHVYSSAAHFADVAGREAGESWKSILN SLYELLAALIRGNRKNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKE GHIKSIISLLDKHGRNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNH VSSMRPNIFLGVSEGSAQYKKWYYELMVDHTEPFVTAEATHLRVGWASTEGYSPYPGGGE EWGGNGVGDDLFSYGFDGLHLWSGCIARTVSSPNQHLLRTDDVISCCLDLSAPSISFRIN GQPVQGMFENFNIDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCYEAVLPKEK LKVEHSREYKQERTYTRDLLGPTVSLTQAAFTPIPVDTSQIVLPPHLERIREKLAENIHE LWVMNKIELGWQYGPVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVG ISDEHAEEKVKKMKLPKNYQLTSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDR IRQGWTYGIQQDVKNRRNPRLVPYTLLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQDH AARAEVCSGTGERFRIFRAEKTYAVKAGRWYFEFEAVTAGDMRVGWSRPGCQPDQELGSD ERAFAFDGFKAQRWHQGNEHYGRSWQAGDVVGCMVDMNEHTVMFTLNGEILLDDSGSELA FKDFDVGDGFIPVCSLGVAQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITMWL SKRLPQFLQVPSNHEHIEVTRIDGTIDSSPCLKVTQKSFGSQNSSTDIMFYRLSMPIECA EVFSKSVAGGLPGASLFGPKNDLEDYDADSDFEVLMKTAHGHLVPDRVDKDKEATKPEFN NHKDYAQEKPSRLKQRFLLRRTKPDYSTSHSARLTEDVLADDRDDYDYLMQTSTYYYSVR IFPGQEPANVWVGWITSDFHQYDTGFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAG ESMSPGQGRNNNGLEIGCVVDAASGLLTFIANGKELSTYYQVEPSTKLFPAVFAQATSPN VFQFELGRIKNVMPLSAGLFKSEHKNPVPQCPPRLHVQFLSHVLWSRMPNQFLKVDVSRI SERQGWLVQCLDPLQFMSLHIPEENRSVDILELTEQEELLKFHYHTLRLYSAVCALGNHR VAHALCSHVDEPQLLYAIENKYMPGLLRTGYYDLLIDIHLSSYATARLMMNNEFIVPMTE ETKSITLFPDENKKHGLPGIGLSTSLRPRMQFSSPSFVSISNECYQYSPEFPLDILKAKT IQMLTEAVKEGSLHARDPVGGTTEFLFVPLIKLFYTLLIMGIFHNEDLKHILQLIEPSVF KEAATPEEESDPLEKELSVEDPKLEGAVEEEAKGGQRPKEGLLQMKLPEPVKLQMCLLLQ YLCDCQVRHRIEAIVAFSDDFVAKLQDNQRFRYNEVMQALNMSAALTARKTKEFRSPPQE QINMLLNFKDNKSECPCPEEIRDQLLDFHEDLMTHCGIELDEDGSLDGNSDLTIRGRLLS LVEKVTYLKKKQAEKQVESDSKKSSTLQQLISETMVRWAQESVIEDPELVRAMFVLLHRQ YDGIGGLVRALPKTYTINGVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMN NKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQ KAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAG CGLQSCQMLVSKGYPDIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECF GPALRGEGGNGLLAAMEEAIKIAEDPSRDGPSPNSGSSKTLDTEEEEDDTIHLGNAIMTF YAALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPLGDLVGVISIAFQMPTIAKDGNV VEPDMSAGFCPDHKAAMVLFLDRVYGIEVQEFLLHLLEVGFLPDLRAAASLDTAALSATD MALALNRYLCTAVLPLLTRCAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEV CLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFG AASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVSMMEK QSSMDSEGNFNPQPVDTSNITIPEKLEYFINKYAEHSHDKWSMDKLANGWIYGEIYSDSS KVQPLMKPYKLLSEKEKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTS QVSVDTAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELESKGGGNHPLL VPYDTLTAKEKAKDREKAQDILKFLQINGYAVSRGFKDLELDTPSIEKRFAYSFLQQLIR YVDEAHQYILEFDGGSRGKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLC SGGHASNKEKEMVTSLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLE SVKSALRAFLDNAAEDLEKTMENLKQGQFTHTRNQPKGVTQIINYTTVALLPMLSSLFEH IGQHQFGEDLILEDVQVSCYRILTSLYALGTSKSIYVERQRSALGECLAAFAGAFPVAFL ETHLDKHNIYSIYNTKSSRERAALSLPTNVEDVCPNIPSLEKLMEEIVELAESGIRYTQM PHVMEVILPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLGNILKIIYNNLGID EGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVVSEEDHLKAEARGDMSEA ELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHN FKREEQNFVVQNEINNMSFLITDTKSKMSKAAVSDQERKKMKRKGDRYSMQTSLIVAALK RLLPIGLNICAPGDQELIALAKNRFSLKDTEDEVRDIIRSNIHLQGK NT seq 10581 nt NT seq  +upstreamnt  +downstreamnt atgggggagttgcttaggactgtgtcgctagaccccagtgttgctgctcctgttggaaaa gggcctcagaacctggatgatgaagtggttctgcagtgtacagccaccatccacaaggaa cagcagaaactatgcttggcagcagaaggatttggcaacagactttgtttcttggagtct acttccaattccaagaatgtccccccagacctctccatctgcacctttgtcctggaacag tccctgtcagtccgggccctgcaggagatgctggctaacaccgtggagaaatcagaaggg caagttgatgtggaaaaatggaaattcatgatgaagaccgctcaaggtggtggtcatcga acactcctctatggacatgccatattgctacgccattcctacagtggcatgtatctgtgc tgcctgtccacctcccggtcttcaactgataagctggcttttgatgtcggcttgcaagag gacaccacaggtgaggcttgttggtggaccattcatcctgcctctaagcagcgatcagaa ggagaaaaagtccgagtgggagatgacctcatcctagttagcgtgtcctctgaaaggtac ttgcacttgtcttatggcaatggcagcttacacgtggatgctgctttccagcagactctc tggagcgtggccccaatcagctcaggaagtgaagcagcccaagggtatctgattggtggt gatgtcctcaggttactgcatggacatatggacgaatgtctcactgtcccttcaggagaa catggtgaagagcaacgaagaactgttcattatgaaggcggtgccgtatctgttcatgca cgttccctttggagactggagacactaagagttgcatggagtggaagccacataagatgg ggccagccgttccgactacgccacgtcacaacggggaaatacttgagtctcatggaagac aaaaaccttctactcatggataaagagaaagctgatgtaaaatcaaccgcatttacattc cggtcttccaaggaaaaattggatgtaggcgtgagaaaagaaattgatggcatgggaaca tctgaaataaaatacggagactcagtttgctatatacaacatgtagatacaggcctgtgg cttacttaccagtcggtggatgtgaaatctgtgagaatgggatctatacaacgtaaggct attatgcaccatgaaggccacatggatgatggcataaacttatctagatctcagcatgaa gaatcacgcacagcacgagtcatccgaagcacagtcttccttttcaatagattcataaga ggccttgatgctctgagcaagaaagcaaaggcttccacagtagatctgcctatagagtcc gtaagtctgagtctgagggatctgattggctatttccacccccctgatgagcatttagaa catgaagacaaacagaacagactacgtgccctgaagaatcggcaaaatctcttccaggaa gagggaatgatcaacctcgtgctggagtgcatagatcgattgcatgtctatagcagcgca gcgcactttgctgatgtcgctgggcgagaggcaggggaatcttggaagtccattctgaat tctctgtatgagttgctggcggctctaattagaggaaatcgtaaaaactgtgctcaattt tctggctccctggactggttgatcagcagattggaaagactcgaagcttcttctggtatt cttgaagttttacactgtgtgttggtagaaagcccagaagctctaaatattattaaagaa ggacatatcaaatccattatttcacttttagacaagcacggaagaaatcacaaggttctg gacgtcttgtgctcactctgtgtttgccatggggttgcagtccgttctaaccagcatctc atctgtgacaatctccttccaggaagagatctgttattgcagacacgtcttgtcaaccat gttagcagcatgaggcccaatatttttctgggtgtcagtgagggttctgctcagtataaa aaatggtactatgaattgatggtggaccacacagagccgtttgtgacagctgaagcaact cacctgcgcgtgggctgggcttccactgaaggctattctccctaccctggagggggcgaa gagtggggtggaaatggtgttggagatgatctcttctcctatggatttgatggacttcac ctctggtcaggttgtatcgctcgtactgtaagctcaccaaaccaacatctgttgagaact gatgatgtcattagttgctgtttagatctaagtgccccaagcatctcatttcgaattaat ggacagcctgttcaaggaatgtttgagaatttcaacatcgatgggctcttctttccagtt gttagtttttctgcaggaataaaggtacgctttctacttggggggcgacatggagaattc aaatttcttcctccccccgggtatgctccttgttatgaagccgttctgccgaaagaaaaa ttgaaagtggaacacagccgagagtacaagcaagaaaggacttacacacgagacctgctg ggccctaccgtttccctgacacaagccgccttcacaccaatccccgtggataccagccag atcgtgctgcctcctcatctagaaaggataagagagaaactggcagagaatatccatgaa ctgtgggttatgaataaaattgaacttggatggcagtatggtccggttagagacgacaat aagagacaacacccatgtctggtggagttctccaagcttcctgaacaggaacgcaattac aacttacaaatgtcacttgagaccctgaagactttgttggcattaggatgtcatgtggga atatcagatgaacatgctgaagaaaaggtgaaaaaaatgaagctacccaagaattaccaa ctgacaagtggctacaagcctgcccctatggacctgagctttataaaactcaccccatct caagaagcaatggtggacaagttggcagaaaatgctcacaatgtgtgggcccgggatcga attcggcagggctggacttacggtatccaacaggatgtaaagaacagaagaaaccctcgc cttgttccctacactcttctggatgaccgaaccaagaaatccaacaaggacagcctccgg gaggctgtgcgcacgctgctgggttatggttacaacctggaagcaccagatcaagaccat gctgccagagccgaggtgtgcagtggcacaggggagcggttccgaatcttccgtgctgaa aagacctacgcggtgaaggcgggccgctggtattttgaatttgaagccgtcactgctgga gacatgagagttggatggagcaggccaggttgtcaaccagatcaggagctgggctcagat gaacgtgcttttgcttttgatggcttcaaggcccagcggtggcaccagggtaatgaacac tatgggcgctcttggcaagcaggcgacgtggtggggtgtatggttgacatgaatgaacac accgtgatgttcacgctgaacggtgaaatccttcttgatgattcagggtcagaactggct ttcaaggactttgacgttggtgatggattcatacctgtatgtagccttggagtggctcaa gtgggcagaatgaactttggaaaggatgtcagcaccttgaaatatttcaccatctgtggc ttacaagagggctatgaaccatttgccgttaacacaaacagggatattaccatgtggctg agcaagagactgcctcaatttctccaagttccatcaaaccatgaacatattgaggtgacc agaatagatggcaccatagacagttccccatgtttgaaggtcacccagaagtcttttggg tctcagaacagcagtactgatatcatgttttatcgtctgagcatgccaattgagtgcgca gaagtcttctctaagtctgtggctggaggactccctggtgccagcctctttgggcccaag aatgatttggaggattatgacgcagattccgactttgaggttctaatgaagacagctcat ggccatctggtacccgatcgtgttgacaaagacaaagaagctactaaaccagagtttaat aaccacaaggactatgctcaggaaaagccctctcgtctgaaacaaagatttttgcttaga agaacaaagccagattacagtacaagccattctgcaagactcactgaagatgtccttgct gacgaccgggatgactatgattacttgatgcagacatccacgtactattactcagtgaga atctttcctggacaagaacctgctaatgtctgggtgggctggattacatcagatttccat cagtatgatacaggctttgacttggacagagttcgtacagtaacagttaccctaggagat gaaaaaggaaaagtgcatgaaagcatcaaacgcagcaactgctatatggtatgtgctggt gagagcatgagccctgggcaaggacgcaacaataatggactggagatcggctgtgtggtg gatgctgccagcgggttgctcacgtttattgccaatggcaaggaactgagcacatactat caggtggagccaagtacaaaattatttcctgcggtatttgcacaagctacaagtcccaat gttttccagtttgagttgggaagaataaagaatgtgatgcctctctcggcgggattattc aagagtgagcacaaaaaccctgtgccacagtgtcccccgcgcctccacgtgcagttcctg tcacatgtcctatggagcagaatgcccaaccagtttttgaaggtcgatgtctctcgaata agtgaacgccaaggctggctggtgcagtgtttggatcctctgcagttcatgtctcttcat atccctgaggaaaacagatctgttgacatcttagagttgacagagcaggaggaattgctg aaatttcactatcacactctccgcctctactcggccgtctgtgctcttgggaaccaccgg gtagcccatgccctgtgcagccatgtggatgaacctcagctcctctatgccattgagaac aagtacatgcctggtttgctgcgcaccggctactacgacctgctgattgacatccacctg agttcctatgccactgccagactcatgatgaacaatgagttcattgtacccatgacagag gagacaaagagcatcacccttttccctgatgagaacaagaagcatggcctcccggggatt ggcctcagcacttccctcaggccacggatgcagttttcctcccccagttttgtgagcatt agtaatgagtgctaccagtacagtccagagttcccactggacatcctcaaggccaaaact atacagatgctgacagaagctgtgaaagaaggcagtcttcatgcccgggacccagttggg gggaccactgaattcctcttcgtacctctcatcaaacttttctataccctgctgatcatg ggcatctttcacaatgaggacttgaagcacatcttgcagttgattgagcccagtgtattt aaagaagctgccactccggaggaggagagtgaccctctggagaaagagcttagtgtggaa gacccgaagctggaaggagctgttgaggaagaagccaaagggggtcaaaggcccaaggaa ggcctgctccaaatgaaactgccagagccagttaaactgcagatgtgcctgctgcttcaa tacctctgtgactgccaggtccggcaccggatagaagccattgtagccttttcagatgac tttgtcgctaagctccaagacaatcaacgcttccgatataatgaagtcatgcaagcctta aacatgtcagcggcactcacagccaggaaaacaaaggaatttagatcaccacctcaagaa cagattaatatgcttctcaattttaaggataacaaaagtgaatgtccatgtcctgaagaa atacgtgaccaactattggatttccatgaagatttgatgacacactgtggaattgagctg gatgaagatgggtctctggatggaaatagtgatttaacaattagaggacgcctactgtcc ctggtagaaaaggtgacatacctgaagaagaaacaagcagaaaaacaagttgagagtgac tccaagaagtcctccactctgcagcagttgatttcagagactatggttcgatgggctcaa gagtctgtcattgaagaccctgagttggtgagagccatgtttgtgttgctccatcggcag tacgatggtattgggggtctggtccgggctctgccaaagacctacactataaacggtgtc tccgtggaggataccataaatctgctggcatctcttggtcagattcgttctctgctgagt gtgagaatgggcaaagaagaagagaagcttatgattcgcggattaggggatatcatgaat aataaggtgttttaccagcaccctaatctcatgagggcactgggcatgcatgagactgtg atggaggtgatggtgaacgtcctgggcggtggagagtccaaggaaatcacttttcccaag atggtggccaactgttgccgttttctctgttacttctgtcgaataagtaggcagaatcaa aaagctatgtttgatcatctcagttatttactggaaaacagcagtgttggtcttgcctca ccagctatgagaggttcaacacccctggatgtggcagcagcctcagtgatggataataat gaactagccttagctttgcgtgagccagatctggaaaaggtggttcgttatttggctggt tgtggactgcaaagttgccagatgctggtgtccaagggttatccagacattgggtggaat ccagttgaaggagaaagatatcttgactttctcagatttgcagtcttctgtaatggggag agcgtggaagaaaatgcaaatgttgttgtgagattgctcattcggaggcctgagtgtttt ggtcctgctttgagaggggaaggtgggaatggccttctagcagccatggaagaagccatc aaaatagccgaggatccttcccgagatggtccctcccctaatagcggatccagtaaaaca cttgacacagaagaggaggaagatgacactatccacctggggaatgcgatcatgaccttt tatgcagctttgattgacctcctgggacgctgtgctcctgagatgcatttgattcatgct ggtaagggagaagccatcagaatcaggtctattttgagatctctgattccattgggagat ttggtgggagtaattagcatcgcttttcagatgccaaccatagccaaagatgggaatgtg gtggaacctgacatgtctgcagggttttgcccagatcacaaggcagccatggttttattc cttgacagggtctatggaattgaggttcaagagttcctccttcatcttcttgaagttggc tttctgccagatctccgggctgctgcttctttagatacggctgctttgagtgctacagac atggccttggccctcaaccggtacctttgtacagccgtgttacctttgttaacaagatgt gctcctctgtttgctggcacagagcaccatgcttccctcattgattcactacttcatact gtatataggctttctaagggctgctcacttaccaaagctcaacgggattccatagaagtt tgtttactctctatttgtggccaattgagaccttctatgatgcagcacttactcagaaga ttagtatttgatgttccattattaaatgagcatgcaaagatgcctcttaagctgctgaca aatcattatgaaagatgctggaaatactattgcctgcctggagggtgggggaactttggt gctgcctccgaagaagaacttcatttatccagaaagttgttctggggcatttttgatgcc ctgtctcaaaagaaatatgaacaagaacttttcaaactggcactgccttgcctgagtgca gttgcaggagctttgcctccagactacatggagtcaaattatgtcagtatgatggaaaaa cagtcatcaatggattctgaagggaactttaacccacaacctgttgatacctcaaatatt acaattcctgagaagttggaatacttcattaacaaatatgcagaacattcgcatgacaaa tggtcaatggataagttggcaaatggatggatttatggagaaatatattctgactcttct aaggttcaaccattaatgaagccatataaattattatctgaaaaggaaaaagaaatttat cgctggccaatcaaagaatctttaaaaactatgctggcttggggttggagaattgaaaga acccgggagggagacagcatggctctttataaccggactcgtcgtatttctcagacaagc caggtttctgtagatactgcccatggttatagcccgcgggccattgacatgagcaatgtt acgctctccagagacctgcacgctatggcagaaatgatggctgaaaattaccataatata tgggcaaagaaaaagaaaatggagttggagtccaaaggtggtggaaaccatcctctgctg gtcccctatgatacactgacagccaaagagaaagccaaggatagggaaaaggcacaggac atcctcaagttcttgcagatcaatggatatgctgtatccaggggttttaaggacctggaa ttggacacaccttctattgagaagcgatttgcctatagtttccttcaacaactcattcgc tatgtggatgaagcccatcagtatatcctggaatttgatggtggcagcagaggcaaagga gaacatttcccttatgaacaagaaatcaagttctttgcaaaagtcgttctccctctaatt gatcagtatttcaaaaaccaccgtttatacttcttatcggcagcaagtagacctctctgc tctggaggacacgcatcaaacaaagagaaagaaatggtgactagcctattctgcaaactt ggagttcttgtcaggcataggatttcactatttggaaatgatgcaacatcaattgtcaac tgtcttcatattttgggtcagactttggatgcaaggacagtgatgaagactggcctggag agtgttaaaagtgcactcagagcttttctggacaatgctgccgaggatctggaaaagacc atggaaaatcttaagcagggccagttcacccacacccggaaccaacccaaaggggtgact cagattatcaattacaccacagtggccctgttgccaatgctgtcgtcattatttgaacat attggccagcatcagtttggagaagacctaatattggaagatgtccaggtgtcttgttat agaattctgacgagcttatatgctctgggaaccagcaagagtatttatgtggagaggcaa cgttctgcgttaggagaatgtctagctgcctttgctggtgcctttcctgtggcatttttg gaaactcatctggacaaacacaatatttactctatctacaatactaagtcttcaagagag agagcagctctcagtttgccaactaatgtggaagatgtttgtccaaatataccatctttg gagaaactcatggaagaaatcgtggaattagctgagtccggcattcgctacactcagatg ccacatgtcatggaagtcatactgcccatgctttgtagctatatgtctcgttggtgggag catgggcctgagaacaatccggaaagagctgaaatgtgctgtacagctctgaactcagag cacatgaacacacttctagggaacatactgaaaatcatatacaataacttgggaattgac gagggagcctggatgaagaggttagcagtattttcccagcctattataaataaagtgaaa cctcagctcttgaaaactcatttcttgccattaatggagaaactcaagaaaaaggcagct atggtggtgtctgaggaagaccacctgaaagccgaggccaggggggatatgtcggaggct gaacttctcatcctagatgaattcactacgctggcccgagatctctatgccttctaccct ctcttgattagatttgtggactataacagggcaaagtggctcaaggagcctaacccagaa gcagaggaactcttccgcatggtagctgaagtatttatttactggtcaaaatcccacaat ttcaagagagaagagcagaacttcgttgtacagaatgaaatcaacaatatgtctttcctt attactgataccaagtcaaagatgtcaaaggcagctgtttctgatcaagaaagaaagaaa atgaagcgcaaaggggatcggtattctatgcagacctctcttattgtagcagctctgaag cggttactgcccatcgggttgaacatctgtgcccctggggatcaggagctcattgctctg gccaaaaatcgatttagtttgaaagatactgaggatgaagtacgagatataatccgcagt aatattcatttacaaggcaag

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