Carlito syrichta (Philippine tarsier): 103267705
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Entry
103267705 CDS
T07836
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr00310
Lysine degradation
csyr01100
Metabolic pathways
csyr05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
103267705 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
103267705 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
csyr03036
]
103267705 (DOT1L)
Enzymes [BR:
csyr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
103267705 (DOT1L)
Chromosome and associated proteins [BR:
csyr03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
103267705 (DOT1L)
HMT complexes
Dot1-containing complex
103267705 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
103267705
NCBI-ProteinID:
XP_021571833
Ensembl:
ENSTSYG00000033933
UniProt:
A0A3Q0ECP1
LinkDB
All DBs
Position
Unknown
AA seq
1430 aa
AA seq
DB search
MENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQV
YNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMAEDDLFVDLGAGVGQVVLQVA
AATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIAN
TSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVV
ELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNAT
TPTKVPESKAAGPADAPTDSGAEDEKVGAAVVKKPSPSKARKKKLNKKGRKMVGRKRGRP
KKMSTANPERKPKKSQTALDLLHAQTVSQTASSSPQDAYRSPRSPFYQLPPSVQRHSPHP
LLGAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNAQLLGTAQQLFS
HCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLERDNSELRS
QSLQLLKARCEELKLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQ
ELLQLKSCVPPDDVLSVHLRGKGVPGRELEAEPGRPHLELDGAKFPLPQLSGMSPELSMN
GHAAAYELCGALSRPASKQNTPQYLASPLDQEVVPCTPSHGGRPRLEKLSGLAVPDYTRL
SPAKIVLRRHLSQDHAVSGKASELHPRVEPAKENGLPYQSPSMAGSMKLSPRDPRPMSPG
ALQIPGEKSSEKGLRERAYGGGGEPITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAER
ARSTPSPVPQPRESSSTLEKQIGANPHGAGSKSLALAPAGFSYTGSVAISGALAGSPASL
GPGSEAAAFDESSSSGSLFATVGSRSSTPQHPPLLVQPRNSRPASPAHQLSASPRLGGAA
PGPLPDSSKGDLPSDSGFSDPESEAKRRVVFTISAGSSKQSPSSKHSPLAAGARGDGQSH
GQDSRKRGRRKVSNINQPLEITAISSPETSLKSSPAPYQDHDQPPVLKKERPLSQPNGAH
YSPLTSDEEPGSEDEPGSARIERKIATISLESKSPPKTLENGGPLAGRKPAPAGEPINSS
KWKSTFSPISDIGLAKSADSPLQAGSALSQNSLFAFRPAADEPAADTKLAAHPRKGFPGS
LAGADGPSPNSKPSNGFAFGGGLATDLSLHSFGDGAPLPKGPEAAGLGAPLSFPSQRGKE
ASEANPFLNKRQLDGLAGLKGEGGKAKEAAEPVDKGALSLSKTKGRDRELDLKNGHNLFI
SAAAVPPGGLLSSPGLAPAASSTAGVAPSAQTHRPFLGAFPPGPQFALGPMSLQANLSSV
AGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGNFSSGVAGGTVGGN
NT seq
4293 nt
NT seq
+upstream
nt +downstream
nt
atggagaattatgttctgatcgactatgacaccaagagcttcgagagcatgcagcggctc
tgtgacaagtacaaccgggccatcgacagcatccaccaactgtggaagggcaccacgcag
cccatgaagctgaacacgcggccgtccaacgggctcctgcggcacatcctgcagcaggtt
tacaaccactcggtgaccgaccccgagaagctcaacaactacgagcccttctcccccgag
gtgtacggggagacctcctttgacctggtggcccagatgatcgacgagatcaagatggcc
gaggacgacctgttcgtggacttgggtgcaggggtgggccaagtcgtgctccaggtcgca
gcggccactaactgcaagcatcactatggcgtcgagaaagcggatatcccggccaagtac
gcggagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcc
gaatacacattggagaggggtgacttcctctcggaagagtggcgggagcgcatcgccaac
acgagtgtcatctttgtgaataactttgcctttggcccggaggtggatcaccagctgaag
gagcgctttgcgaacatgaaggaaggtggcagaattgtgtcctcgaaaccttttgcgcct
ctaaacttcagaataaacagtagaaacttgagtgacatcggcacgatcatgcgcgtggtg
gagctgtcgcccctgaagggctcggtgtcgtggacggggaagccggtctcctactacctg
cacaccattgaccggaccatacttgaaaactatttttctagtctgaaaaatccaaaactc
agggaggaacaggaggccgcacggcgccggcagcagcgtgagaacaagagcaatgcaacc
acccccaccaaggtccccgagagcaaggcagctggccccgcagatgcccccacggactct
ggtgctgaggacgagaaggtgggggccgccgtcgtcaagaagccgtcgccctctaaggcc
cgcaagaagaagctgaacaagaaggggcggaagatggtgggccgcaagcgcgggcgcccc
aagaagatgagtaccgcgaaccccgagcgcaaacccaagaagagccaaaccgcactggat
ctcctgcacgcgcagaccgtgtcccagacggcatcctcctcgccccaggatgcctacagg
tcccctcgcagcccgttctaccagctacctccgagcgtgcagaggcactccccccacccg
ctgctgggggcgcccaccccacctgcgctgcagaagctgctagaatccttcaagattcag
tacttgcagttcttggcctacacaaagactccccagtacaaggccaacctgcagcagttg
ctggaccaggagaaggagaagaacgcccagctgctgggcacggcgcaacagctcttcagc
cactgccaggctcagaaggaggagatcaggaggctgttccagcagaagctggacgagctg
ggtgtaaaggccctcacctacaacgacctgatccaggcccagaaggagatctctgcgcac
aaccagcagctgcgcgagcagtctgagcagctggagcgagacaacagcgagctgcgcagc
cagagcctgcagctgctcaaggcccgctgcgaggagctgaagctggactgggccacgctg
tccctggagaaactgctgaaggagaaacaggccctgaagagccagatctccgagaaacag
cggcactgcctggagctgcagatcagcatcgtggagctggaaaagagccagcggcagcag
gagctcctgcagctcaagtcttgcgtgccgcccgatgacgtgctgtctgtgcacctgcgt
gggaagggcgtgccaggccgtgagctggaggcggagcccggccggccgcacctggagctg
gacggcgccaagttcccgctgccccagctgagtggcatgagccccgaactctccatgaac
ggccacgctgctgcctatgagctgtgtggtgcacttagccggcccgcgtccaagcagaac
acaccgcagtacctggcgtcgcccctagaccaggaggtagtgccctgcacccccagccac
ggtggccggccgcgcctggagaaactgtctggtctggctgtgcccgactatacccggctc
tcgcctgccaagatcgtgctcaggaggcatctgagccaggaccacgcagtctccggcaag
gccagcgagctgcacccacgagtcgagcctgccaaggagaacggcctgccctaccagagc
cccagcatggccggcagcatgaagctgagccctcgggacccgcgccccatgtccccgggg
gccctgcagattcccggagagaaaagcagcgagaagggcctgagagagcgcgcctacggc
ggcggcggcgagcctatcaccagcctgcccatcagcatcccgctcagcacggtgcagccc
aacaagctcccggtcagcatccccctggccagcgtggtgctgcccagccgcgccgagagg
gcgaggagcaccccgagtccagtgccgcagcctcgagagtcctcgtccacacttgaaaag
cagattggtgctaacccccacggtgctgggagcaagagccttgccctggcccctgcaggc
ttctcctacactggctcggtggccatcagcggtgccctggccggcagcccggcctccctc
ggccccgggtctgaggcggccgccttcgacgagtcctccagctcggggagcctgtttgcc
actgtggggtctcgcagctcaactccccagcaccctccgttgctagtgcagccccgaaac
tcgcgcccggcctctcccgcccaccagctctccgccagcccccggctcggtggggctgcc
ccaggcccactccccgactccagcaagggggacctgccctcagattctgggttttcggac
ccggagagcgaggccaagaggagggtcgtcttcaccatctctgcgggcagctccaagcag
tcaccttccagcaagcacagccccctggctgcgggtgcccgcggggatggccagagccat
gggcaggacagccgcaagcggggtcggcggaaggtcagcaacatcaaccagcctctggag
atcacggccatctcatcccccgagacctcgctgaagagctcccccgcgccctaccaggac
cacgaccagccccccgtgctcaagaaggagcggcccctgagccagcccaacggggcacac
tactccccgctcacctcggacgaggagcctggctctgaggacgagcccggcagtgcccga
atcgaaaggaaaatcgcaacaatctccctagaaagcaaatctccccccaaaaccttggaa
aatggcggccccttggcaggccggaagccagcgcccgcgggcgagcccatcaacagcagc
aagtggaaatccaccttctcgcccatctccgacattggcctggccaagtctgcggacagc
ccgctgcaggctggctctgccctgagccagaactccttgttcgccttccggcctgcagca
gacgagcccgccgccgacaccaagctggccgcccacccccggaaaggcttccccggctcc
ctggcgggtgccgacgggcccagccccaacagcaagccctccaatggcttcgctttcggc
gggggcctggccacagacctcagtttacacagcttcggcgacggtgctcccctgcccaag
ggccccgaggcggccggcctgggcgccccgctcagctttccttcgcagcggggcaaggag
gcctcagaggccaaccccttcctgaacaagaggcagctggacggcctggccggcctgaag
ggcgagggcggcaaggccaaggaggcggccgagcccgtggacaagggcgccctgtcgctc
agcaagaccaagggccgggaccgcgagctggacctcaagaacggccacaacctcttcatc
tcggcggccgccgtgcccccggggggcctcctcagcagccctggcctggccccggcggcg
tcctccacagccggcgtggccccctccgcccagacgcaccggcccttcctgggcgccttc
ccccccgggccgcagttcgccctgggccccatgtccctgcaggccaacctcagctcagtg
gccggctcgtccgtgctgcagtcgctgttcagctccgtgccggccgccgcgggcctggtg
cacgtgtcgtctgctgccacccgcctgaccaactcgcacgccatgggcaacttctcctcc
ggggtggctggcggcacagttggaggtaactag
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