Carlito syrichta (Philippine tarsier): 103271179
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Entry
103271179 CDS
T07836
Symbol
BRAF
Name
(RefSeq) serine/threonine-protein kinase B-raf
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr01521
EGFR tyrosine kinase inhibitor resistance
csyr01522
Endocrine resistance
csyr04010
MAPK signaling pathway
csyr04012
ErbB signaling pathway
csyr04015
Rap1 signaling pathway
csyr04024
cAMP signaling pathway
csyr04062
Chemokine signaling pathway
csyr04068
FoxO signaling pathway
csyr04150
mTOR signaling pathway
csyr04270
Vascular smooth muscle contraction
csyr04510
Focal adhesion
csyr04650
Natural killer cell mediated cytotoxicity
csyr04720
Long-term potentiation
csyr04722
Neurotrophin signaling pathway
csyr04726
Serotonergic synapse
csyr04730
Long-term depression
csyr04810
Regulation of actin cytoskeleton
csyr04910
Insulin signaling pathway
csyr04914
Progesterone-mediated oocyte maturation
csyr04928
Parathyroid hormone synthesis, secretion and action
csyr04934
Cushing syndrome
csyr05010
Alzheimer disease
csyr05022
Pathways of neurodegeneration - multiple diseases
csyr05034
Alcoholism
csyr05160
Hepatitis C
csyr05161
Hepatitis B
csyr05200
Pathways in cancer
csyr05205
Proteoglycans in cancer
csyr05208
Chemical carcinogenesis - reactive oxygen species
csyr05210
Colorectal cancer
csyr05211
Renal cell carcinoma
csyr05212
Pancreatic cancer
csyr05213
Endometrial cancer
csyr05214
Glioma
csyr05215
Prostate cancer
csyr05216
Thyroid cancer
csyr05218
Melanoma
csyr05219
Bladder cancer
csyr05220
Chronic myeloid leukemia
csyr05221
Acute myeloid leukemia
csyr05223
Non-small cell lung cancer
csyr05224
Breast cancer
csyr05225
Hepatocellular carcinoma
csyr05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103271179 (BRAF)
04012 ErbB signaling pathway
103271179 (BRAF)
04015 Rap1 signaling pathway
103271179 (BRAF)
04068 FoxO signaling pathway
103271179 (BRAF)
04024 cAMP signaling pathway
103271179 (BRAF)
04150 mTOR signaling pathway
103271179 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103271179 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103271179 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
103271179 (BRAF)
04062 Chemokine signaling pathway
103271179 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
103271179 (BRAF)
04914 Progesterone-mediated oocyte maturation
103271179 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
103271179 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
103271179 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
103271179 (BRAF)
04720 Long-term potentiation
103271179 (BRAF)
04730 Long-term depression
103271179 (BRAF)
04722 Neurotrophin signaling pathway
103271179 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103271179 (BRAF)
05205 Proteoglycans in cancer
103271179 (BRAF)
05208 Chemical carcinogenesis - reactive oxygen species
103271179 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
103271179 (BRAF)
05212 Pancreatic cancer
103271179 (BRAF)
05225 Hepatocellular carcinoma
103271179 (BRAF)
05226 Gastric cancer
103271179 (BRAF)
05214 Glioma
103271179 (BRAF)
05216 Thyroid cancer
103271179 (BRAF)
05221 Acute myeloid leukemia
103271179 (BRAF)
05220 Chronic myeloid leukemia
103271179 (BRAF)
05218 Melanoma
103271179 (BRAF)
05211 Renal cell carcinoma
103271179 (BRAF)
05219 Bladder cancer
103271179 (BRAF)
05215 Prostate cancer
103271179 (BRAF)
05213 Endometrial cancer
103271179 (BRAF)
05224 Breast cancer
103271179 (BRAF)
05223 Non-small cell lung cancer
103271179 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
103271179 (BRAF)
05160 Hepatitis C
103271179 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
103271179 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
103271179 (BRAF)
09165 Substance dependence
05034 Alcoholism
103271179 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103271179 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103271179 (BRAF)
01522 Endocrine resistance
103271179 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
csyr01001
]
103271179 (BRAF)
Enzymes [BR:
csyr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
103271179 (BRAF)
Protein kinases [BR:
csyr01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
103271179 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
103271179
NCBI-ProteinID:
XP_008066825
Ensembl:
ENSTSYG00000009251
UniProt:
A0A1U7U9R8
LinkDB
All DBs
Position
Unknown
AA seq
715 aa
AA seq
DB search
MIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGNDFSVS
SSASTDTVTSSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPAR
CGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPL
TTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVS
KFFEHHPIPQEEASLAETALTSGSSPSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADED
HRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLSN
VKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVY
KGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWC
EGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKI
GDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTG
QLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILA
SIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2148 nt
NT seq
+upstream
nt +downstream
nt
atgattaagttgacacaggaacatatagaggccctattggacaaatttggtggggagcat
aatccaccgtcaatatatctggaggcctatgaagaatacaccagcaagctagatgcgctt
caacaaagagaacagcagttattggaatccctggggaatggaaatgatttttctgtttct
agctctgcatcaacagacaccgttacatcttcttcctcttctagcctttcagtactaccc
tcatctctttcagtttttcaaaatcccacagatgtgtcacggagcaaccccaagtcacca
caaaaacctattgttagagtcttcctgcccaacaaacagaggacagtggtacctgcaaga
tgtggcgttacagtccgagacagtctaaagaaagcactgatgatgagaggtctaattcca
gagtgctgcgctgtttacagaattcaggatggagagaagaaaccaattggctgggacact
gatatttcctggcttactggagaagaattacatgtagaagtgttggaaaatgttccactt
acaacacacaactttgtacggaaaacgtttttcaccttagcattttgtgacttttgtcga
aagctgcttttccagggtttccgttgtcaaacatgtggttataaatttcatcagcgctgt
agtacagaagttccactgatgtgtgttaattatgaccaacttgatttgctgtttgtgtcc
aagttctttgaacatcacccaataccacaggaagaggcctccttagcagagactgccctt
acatctggatcatccccttctgcacccccttcagactctattgggccccaaatactcacc
agtccgtctccttcaaaatccattccaattccacagcccttccgaccagcagatgaagat
catcgaaatcaatttggacaacgagataggtcctcatcagctcccaatgtgcacataaac
acaatagagcctgtcaatatagatgacttgattagagaccaagggttccgtggtgatgga
gggtcaaccacaggtttgtctgccaccccccctgcctcactacctggctcactctctaat
gtgaaagccttacagaaatctccaggacctcagcgagaaaggaagtcatcttcatcctca
gaagacagaaatcgaatgaaaacacttggtagacgagattcaagtgatgattgggagatt
cctgatggccagattacagtgggacagagaattggatctggatcatttggaacagtctac
aagggaaagtggcatggtgatgtcgcagtgaaaatgttgaatgtgacagcacctacacct
caacagttacaagccttcaaaaatgaagtaggagtactcaggaaaacacgacatgtgaat
atcctactcttcatgggctattccacaaagccacaactggctattgttacccagtggtgt
gagggttccagtttatatcaccatctccacatcattgagaccaaattcgagatgattaaa
cttatagatattgcacggcagactgcacaaggcatggattacttacacgccaagtcaatc
atccacagagacctcaagagtaataatatatttcttcatgaagacctcacagtaaaaata
ggtgattttggtctagccacagtgaaatctcgatggagtgggtcccatcagtttgaacag
ttgtctggatccattttgtggatggcaccagaagtaatcagaatgcaagataaaaaccca
tacagctttcaatcagatgtatatgcatttggaattgttctgtatgaactgatgactgga
cagttaccttattcaaacatcaacaatagggaccagataatttttatggtgggacgagga
tacttatcgccagatctcagtaaggtacggagtaactgtccaaaagccatgaagagatta
atggcagagtgcctcaaaaagaaaagagatgagagaccactctttccccaaattctcgcc
tctattgagctgctggcccgctcattgccaaaaattcaccgcagtgcatcagaaccctcc
ttgaatcgggctggtttccaaacagaggattttagtctatatgcttgtgcttctccaaaa
acacccatccaggcagggggatatggagaatttgcagccttcaagtag
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integrated database retrieval system
