| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
csyr Carlito syrichta (Philippine tarsier)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:csyr00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
103271439 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
103271439 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
103271439 (ABCC1)
04981 Folate transport and metabolism
103271439 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
103271439 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103271439 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:csyr02000]
103271439 (ABCC1)
Enzymes [BR:csyr01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
103271439 (ABCC1)
Transporters [BR:csyr02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
103271439 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1678 aa
MTHLNKAKTALGFLLWIVCWADLFYSFWERSQGIFLAPVFLVSPTLLGITMLLATLLIQL
ERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALREDAQVDLFRDITFYVYFSLVLAQL
VLSCFSDRAPLFSETINDPNPCPESGASFLSKITFWWITGLMIRGYRQPLESSDLWSLNK
EDTSEQVVPVLVKNWKKECAKSRKQPRKIVYTSKEPAKPKGGSKVDVNEEAEALIIKSPQ
KERDPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFMNDTKAPDWQGYFY
TALLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNL
MSVDAQRFMDLATYINMIWSAPLQVILAVYLLWLNLGPSILAGVAVMVLMVPLNAVMAMK
TKTYQVAHMKSKDSRIKLMNEILNGIKVLKLYAWELAFKDKVLDVRQEELKVLKKSAYLG
AVGTFTWVCTPFLVALCTFAVYVTVEKHSILDAQKAFVSLALFNILRFPLNILPMVISSI
VQASVSLKRLRIFLSHEELEPDSIERRPLKDGGGTNSITVKNATFTWARSDPPTLNGITF
SVPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGCVTLKGSVAYVPQQAWIQNDSLRENI
LFGRPLQEQYYKAVVEACALLPDLEILPTGDRTEIGEKGVNLSGGQKQRVSLARAVYCNS
DIYLFDDPLSAVDAHVGKHIFENVVGPKGMLKNKTRLLVTHSISYLPQVDVIIVMSGGKI
SEMGSYQELLARDGAFAEFLRTYTSTEQDQASDGDGLAGLGGPGKEAKQLENGMLVTDSA
GKQLQRQLSGSSSYSGDGGRHHSSTAELQKAGAKPEETWKLMEADKAQTGQVKLSVYWDY
MKAIGLFISFLSLFLFLCNHVAALASNYWLSLWTDDPVVNGTQEHTKLRLSVYGTLGISQ
GVAVFGYSMAVSIGGIFASRRLHLDLLHNVLRSPMAFFERTPSGNLVNRFSKELDTVDSM
IPQVIKMFMGSLFNVVGACIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESV
SRSPVYSHFSETLLGVSVIRAFEEQERFIRQSDRKVDENQKAYYPSIVANRWLAVRLEYV
GNCIVLFAALFTVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKE
YSETEKEASWHIPETAPPSTWPQVGRVEFRNYCLRYRDDLDLVLRHINVTIDGGEKVGIV
GRTGAGKSSLTLGLFRITESSEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRM
NLDPFSQYSDEEVCQPQSHTRVQQRSSGQCSHTRTVSRQPRCSQLGSACVWGRLAPRPEW
RVRGGLTFCLLVFVLLPSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIR
TQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGSPSELLQQRGLFYSMAKDAGLALS
CWEPTPQCCLHQCLRQRSEAACAPPLLSSSKDLVALTDDPDLELQSQGWSTGLTAAGLPI
PTIQPSFPSCLFSLLLSVHTTGKGKVDDWHPLFISDLERHRQSHLQPMGPGESHDPSQAI
EEGFTCNLLDEEVASAPLQLAAAAPGKEVLLCLYSVSALGSAFAKLFSWEGSPQAGEE |
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| NT seq |
5037 nt +upstreamnt +downstreamnt
atgacacatctcaacaaagccaaaactgccttgggatttctgctgtggatcgtctgctgg
gcagacctcttctactctttctgggaaagaagtcagggcatctttctggccccagtgttt
ctggtcagcccaactctcttgggcatcaccatgctgcttgccaccctcttaattcagctt
gagaggaggaagggggtccagtcctcagggatcatgctcactttctggcttgttgccctc
ctgtgtgccctcgctatcttgaggtccaaaatcatgactgccttacgggaggatgcccag
gtcgacctgttccgtgacatcactttctacgtctacttttcactcgtgctggctcagctc
gtgttgtcctgtttctcagaccgtgcacccctgttctccgaaaccatcaatgaccccaat
ccctgcccggaatccggcgcctccttcctgtccaagatcaccttctggtggatcacgggg
ttgatgattcggggctaccgccagcccctggagagcagtgacctctggtccctaaacaag
gaggacacgtcggaacaagtcgtgccagttctggtaaagaactggaagaaggagtgtgcc
aagtcaaggaagcagccgagaaagatcgtgtatacctccaaggaacctgccaagcccaag
gggggctccaaggtagatgtgaacgaggaggcggaggccttgattatcaagtccccacag
aaggagcgagacccctcactgttcaaggtgttatacaagacttttggaccctacttcctc
atgagctttctgttcaaggccctgcacgacttgatgatgtttgccggcccggagatctta
aagttgctcatcaacttcatgaacgacacgaaggccccagactggcagggctacttctac
acggcgctgctgttcgtcagcgcctgtctgcagacgctcgtgctgcaccagtactttcat
atctgctttgtcagtggcatgcgcatcaagaccgccgtcattggggctgtttaccggaag
gccctggtgatcaccaactcggccagaaaatcctccacggtcggggagatcgtcaacctc
atgtctgtggacgcccagaggttcatggacctggccacgtacattaacatgatctggtca
gcccctctgcaagtcatccttgctgtctacctcctgtggctgaacctgggcccttccatc
ctggctggggtggctgtgatggtcctcatggtgccccttaatgctgtgatggcgatgaag
accaagacctaccaggtagcccacatgaagagcaaggacagtcggatcaagctgatgaac
gagatcctcaacgggatcaaggtgctcaagctgtatgcctgggagctggcgttcaaggac
aaggtgctggatgtccggcaggaggagctgaaggtgctgaagaagtctgcctacctgggt
gccgtggggaccttcacctgggtctgcacgcctttcctggtggccctgtgtacgtttgcc
gtctacgtgactgtcgagaagcacagcatcctggatgcccagaaagccttcgtgtcctta
gccttgttcaacatcctccgcttccccctgaatatccttcccatggtcatcagcagcatc
gtgcaggcaagtgtctccctcaaacgactccggatcttcctctcccacgaggagctagag
cccgacagcatcgagcggcggcctctcaaagacggtggggggacaaacagcatcaccgtg
aagaacgccacattcacctgggccaggagcgacccgcccacgctgaatggcatcaccttc
tcggttccagaaggttccttggtggccgtggtgggtcaggtgggctgtggaaagtcgtct
ctgctctctgccctcttggccgagatggacaaggtagaggggtgcgtgactctcaagggc
tcagtggcctacgtgccccagcaggcctggatccagaacgattctctccgagaaaatatt
ctctttggacgcccactgcaggaacagtattacaaggctgtggtagaggcttgtgccctc
ctcccagaccttgaaatcctgcccaccggagaccggacagagataggcgagaagggcgtg
aacctgtctgggggccagaagcagcgtgtgagcctggcgcgggccgtgtactgcaactcc
gatatttacctcttcgatgatcccttgtcagcggtagatgcccacgtgggaaaacacatc
tttgaaaatgtggttggccctaaggggatgctgaagaacaagacacgcctcctggtcaca
cacagcatcagctacctgccgcaggtggacgtcatcatcgtcatgagtggtggcaagatc
tctgagatgggctcctaccaggagctgctggcccgcgacggggccttcgctgagttcctg
cgcacgtacaccagcaccgagcaagatcaggcctcagacggggacgggttggcgggtctt
ggaggtcccgggaaggaggcaaagcagttggagaacggcatgctggtgacagactctgcg
ggcaagcaactgcagaggcagctcagcggctcctcctcgtatagtggggacggtggcagg
caccacagcagcacggccgagctgcagaaagctggggccaagccagaggagacctggaag
cttatggaggcggacaaggctcagacagggcaggtcaagctctctgtgtactgggactac
atgaaggccatcgggctgttcatctccttcctgagcctcttcctcttcttgtgcaaccac
gtggctgccctggcctccaactattggctcagtctctggaccgatgaccccgttgtcaac
gggacccaggagcacaccaaactccggctaagcgtctacggaaccctgggcatttctcaa
ggtgtcgccgtgtttggctactccatggcagtgtccattgggggcatcttcgcctcccgc
cgcctgcacctggacctgctgcacaacgtcctgcggtcgcccatggccttcttcgagcgg
acgcccagtgggaacctggtgaaccgcttctccaaggagctggacacggtggactccatg
atcccacaggtcatcaagatgttcatgggctccctgttcaacgtcgtgggtgcttgcatc
atcatcctgctggccacgcccattgccgccgtcatcatcccgcccctgggcctggtctac
ttcttcgtccagaggttctatgtggcgtcctcgcggcagctgaagcgcctggagtcggtg
agccgctccccagtgtactcccacttcagcgagaccctgctgggggtcagcgtcatccgc
gccttcgaggagcaggagcgcttcatccgccagagtgaccggaaggtggacgagaaccag
aaggcttactaccccagcatcgtggccaacaggtggctggccgtgcggctggagtatgtg
ggcaactgcatcgtcctgtttgctgccctgttcactgtgatctctcgtcacagcctcagt
gctggcttggtgggcctctcggtgtcctactcattgcaggtcaccacatacttgaactgg
ctggtccggatgtcctctgagatggagaccaacattgtggccgtggagaggctcaaggag
tattcagaaaccgagaaggaggcttcctggcacatcccggagacagcgccacccagcacc
tggccgcaggtgggccgcgtggagttccggaactactgcctgcgctaccgggacgacctg
gacctggtgctcaggcacatcaatgtcaccatcgacgggggagagaaggtcggcatcgtg
gggcggacaggagctgggaagtcctccctgaccctgggtctgtttcggatcaccgaatct
tctgaaggagagatcatcatcgatggcatcaacatcgccaagattgggctacacaacctc
cgcttcaaaatcaccatcatcccacaggaccctgtgctgttctcgggttccctccgcatg
aacctggatccattcagccagtactcagatgaggaggtctgccagccacaaagccacact
cgtgtccagcagcgcagcagtggtcagtgctcccataccaggacagtcagcaggcagccc
cgctgctctcagctgggctctgcatgcgtctggggtcggctggcacccaggcctgagtgg
agggtcaggggtggtctgaccttctgtctcttggtctttgtcctcctgcccagtgttggg
cagcgtcagctcgtgtgtctggcccgggccctgctgaggaagaccaagatcctcgtgctg
gatgaggccacagcggccgtggacctggagacagatgacctcatccagtctaccatccgg
acgcagtttgacgactgcactgtgctgaccatcgcccaccggctcaacaccatcatggac
tacacaagggtgatcgtcctagacaaaggagaaatccgagagtgtgggtccccctccgaa
ctcctgcagcagagaggtctcttctacagcatggccaaagatgctggcttggcactcagt
tgctgggaaccgacaccccagtgctgcctccaccagtgcttgcgccagaggtctgaggcg
gcctgtgcacccccgctcctgtcctcctcgaaggacttggttgcactgacagatgacccc
gacctggaactccagagccagggatggtcgacggggctgactgcagctgggctccccatc
cccaccatccagccttcctttccttcctgcctcttttctttgctcctctcggttcacaca
acagggaaagggaaggtggatgactggcaccccctctttatctcagacctggagcgacac
aggcagtcccacttgcagcccatgggcccaggagagtcacatgaccccagccaagccata
gaggaagggttcacgtgtaacctgcttgatgaagaggtggcatcggcccccctccagcta
gctgctgcggcaccggggaaggaagttttgttgtgcctctattctgtgtcggccctgggc
tcagcctttgcaaagctcttctcatgggaagggtccccccaggctggagaggagtga |
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