Carlito syrichta (Philippine tarsier): 103272228 Help Entry 103272228         CDS       T07836                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism csyr  Carlito syrichta (Philippine tarsier) Pathway csyr00230   Purine metabolism csyr01100   Metabolic pathways csyr01522   Endocrine resistance csyr04015   Rap1 signaling pathway csyr04020   Calcium signaling pathway csyr04022   cGMP-PKG signaling pathway csyr04024   cAMP signaling pathway csyr04062   Chemokine signaling pathway csyr04072   Phospholipase D signaling pathway csyr04081   Hormone signaling csyr04082   Neuroactive ligand signaling csyr04114   Oocyte meiosis csyr04211   Longevity regulating pathway csyr04213   Longevity regulating pathway - multiple species csyr04261   Adrenergic signaling in cardiomyocytes csyr04270   Vascular smooth muscle contraction csyr04371   Apelin signaling pathway csyr04540   Gap junction csyr04611   Platelet activation csyr04713   Circadian entrainment csyr04714   Thermogenesis csyr04723   Retrograde endocannabinoid signaling csyr04724   Glutamatergic synapse csyr04725   Cholinergic synapse csyr04727   GABAergic synapse csyr04742   Taste transduction csyr04750   Inflammatory mediator regulation of TRP channels csyr04911   Insulin secretion csyr04912   GnRH signaling pathway csyr04913   Ovarian steroidogenesis csyr04914   Progesterone-mediated oocyte maturation csyr04915   Estrogen signaling pathway csyr04916   Melanogenesis csyr04918   Thyroid hormone synthesis csyr04921   Oxytocin signaling pathway csyr04923   Regulation of lipolysis in adipocytes csyr04925   Aldosterone synthesis and secretion csyr04926   Relaxin signaling pathway csyr04927   Cortisol synthesis and secretion csyr04928   Parathyroid hormone synthesis, secretion and action csyr04934   Cushing syndrome csyr04935   Growth hormone synthesis, secretion and action csyr04970   Salivary secretion csyr04971   Gastric acid secretion csyr04972   Pancreatic secretion csyr04976   Bile secretion csyr05032   Morphine addiction csyr05163   Human cytomegalovirus infection csyr05166   Human T-cell leukemia virus 1 infection csyr05200   Pathways in cancer csyr05207   Chemical carcinogenesis - receptor activation csyr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:csyr00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103272228 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103272228 (ADCY4)    04371 Apelin signaling pathway     103272228 (ADCY4)    04020 Calcium signaling pathway     103272228 (ADCY4)    04072 Phospholipase D signaling pathway     103272228 (ADCY4)    04024 cAMP signaling pathway     103272228 (ADCY4)    04022 cGMP-PKG signaling pathway     103272228 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     103272228 (ADCY4)    04081 Hormone signaling     103272228 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103272228 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     103272228 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103272228 (ADCY4)    04062 Chemokine signaling pathway     103272228 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     103272228 (ADCY4)    04923 Regulation of lipolysis in adipocytes     103272228 (ADCY4)    04912 GnRH signaling pathway     103272228 (ADCY4)    04913 Ovarian steroidogenesis     103272228 (ADCY4)    04915 Estrogen signaling pathway     103272228 (ADCY4)    04914 Progesterone-mediated oocyte maturation     103272228 (ADCY4)    04921 Oxytocin signaling pathway     103272228 (ADCY4)    04926 Relaxin signaling pathway     103272228 (ADCY4)    04935 Growth hormone synthesis, secretion and action     103272228 (ADCY4)    04918 Thyroid hormone synthesis     103272228 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     103272228 (ADCY4)    04916 Melanogenesis     103272228 (ADCY4)    04925 Aldosterone synthesis and secretion     103272228 (ADCY4)    04927 Cortisol synthesis and secretion     103272228 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103272228 (ADCY4)    04270 Vascular smooth muscle contraction     103272228 (ADCY4)   09154 Digestive system    04970 Salivary secretion     103272228 (ADCY4)    04971 Gastric acid secretion     103272228 (ADCY4)    04972 Pancreatic secretion     103272228 (ADCY4)    04976 Bile secretion     103272228 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     103272228 (ADCY4)    04727 GABAergic synapse     103272228 (ADCY4)    04725 Cholinergic synapse     103272228 (ADCY4)    04723 Retrograde endocannabinoid signaling     103272228 (ADCY4)   09157 Sensory system    04742 Taste transduction     103272228 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     103272228 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     103272228 (ADCY4)    04213 Longevity regulating pathway - multiple species     103272228 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     103272228 (ADCY4)    04714 Thermogenesis     103272228 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103272228 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     103272228 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103272228 (ADCY4)    05163 Human cytomegalovirus infection     103272228 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     103272228 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103272228 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103272228 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103272228 (ADCY4) Enzymes [BR:csyr01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103272228 (ADCY4) SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA CD52 Motif Other DBs NCBI-GeneID:  103272228 NCBI-ProteinID:  XP_008067899 Ensembl:  ENSTSYG00000014218 UniProt:  A0A1U7UGS9 LinkDB All DBs Position Unknown AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALVALLAVAWASGRELVSDPS FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWASLLALGHGFLFTGGVVSAWDQV SFFLFVIFTVYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGRQPDSRPALLPQLGANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAQEMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITRATLALLAG AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGASGGLLSSLEGPKMRPSLLMTR YLESWGAAKPFAHLSHVDSPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSALPAFKYYEACTFLIFLSNFI IQMLVTNRPPALAITYSITFLLFFLLLFVCFSEDLMKCVLKGPRMLHWLPALSGLVATRP GLRIALGTATILLVFAMAIASLFVLPASSDCPFRAFNVSSVTFNLSWELPGSLPLISVPY SMHCCVLGFLSCSLFLHMSFELKLLLLLLWLMASCSLFLHSHAWLSDCLIAYLYLDPLDS RPGVLKDPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLIRTGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagcccccggccgccccccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccgctgctactgctgctgctggtgatcgtgctctgcgcg ctggtggcgctgctcgccgtggcctgggccagcggcagggagctagtctcagaccccagc tttctgaccactgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctcgcttcc cgcgagcagcgactgcagcgctggacgcgccccctgtcaggcctcgtgtgggcctcgcta ctcgcgttaggccacggcttcctgttcaccgggggcgtggtgagcgcctgggaccaggtg tccttttttctcttcgtcatcttcaccgtgtacgccatgctgcccttgggcatgcgggac gccgctgtcgcgggcctcgcctcctcgctgtcgcacctgctggtcctcgggctgtacctt gggcggcagccggactcgcggcctgcgctgctgccgcagttgggagcgaacgcggtgctg ttcctgtgcgggaacgtggcgggagcttatcacaaggcgctgatggagcgcgcgctgcgc gccaccttccgggaggcgctcagctccctgcactcacgccggcggctggacaccgagaag aagcaccaggagcaccttctcttgtccatccttcctgcctacctggcccaagagatgaag gcagagatcatggcacgactgcaggctgggcaggggtcacgaccagagagtaccaacaac tttcacagcctctacgtcaaaaggcaccagggagttagtgttctgtatgctgacatcgtg ggcttcacacggctggccagcgagtgctcccctaaggaactggtgctcatgctcaacgag ctctttggcaagttcgaccagatcgctaaggagcatgaatgcatgcggatcaagatcctg ggggactgttactactgtgtctcagggctgccgctctcactgccagaccacgccatcaac tgtgtgcgcatgggactggacatgtgccgggccatcaggaaactgcgggcagccactggt gtggacatcaacatgcgtgtgggtgtgcactcgggcagcgtgctctgtggagtcatcggg ctgcaaaaatggcagtacgatgtctggtcccatgacgtcacactggccaaccacatggag gcgggcggtgtaccagggagagtgcacatcacaagggctaccctggccctgctggcaggg gcttatgctgtggaggatgcaggcatggaacaccgggacccgtaccttcgggagctaggg gagcccacctacctggtcatcgatccccgggccgaggaggaggacgagaagggcgcttcg ggaggtttgctgtcctctcttgagggccccaagatgcgtccatcactgctgatgacccgc tacctggagtcctggggtgcagccaagccttttgcccacctaagccatgtagacagccct gtgtccacctcaacccctctcccggagaaggccctggcctccttcagcccccagtggagc ctggaccggagccgtaccccccggggactagatgatgagctggacactggggatgccaag ttcttccaggtcattgagcagctcaactctcagaaacagtggaagcagtcaaaggacttc aacccactgacactgtacttcagagaaaaggagatggagaaagagtatcgactttctgcg ctccctgccttcaaatactatgaagcctgcaccttcctgatttttctctccaacttcatc attcagatgctggtgacaaacaggcccccagctctggccatcacctatagcatcaccttc ctcctcttcttccttcttctcttcgtctgcttctcagaggacctgatgaagtgtgtcctg aaaggtcccaggatgctgcactggctgcctgcactgtctggcctggtggccacacgacca ggactgcgaatagccctgggcaccgccactatcctccttgtctttgccatggccattgcc agcctgttcgtcttaccagcatcatccgactgccctttccgggctttcaatgtgtcctcc gtgactttcaacctctcctgggagctccctgggtcgttgcctctcatcagtgtcccatac tccatgcactgctgcgtgctgggtttcctgtcctgctccctttttctgcacatgagcttc gagttgaagctgctgctgctactgctgtggctgatggcctcctgttccctcttcctgcac tctcatgcctggctgtccgactgcctcattgcctacctctatctggaccccttggactcc aggccaggagtactgaaggatcccaaactgatgggagctatctccttcttcatctttttc ttcaccctccttgtcctggctcggcagaatgagtattactgccgcctggacttcctgtgg aagaagaagctgaggcaggagcgggaggagaccgagacaatggagaacctgactcggctg ctcttggagaacgtgcttcctgcgcacgtggccccccagttcattggccagaaccggcgc aatgaggatctctaccaccagtcctacgagtgtgtttgtgtcctcttcgcctcagtccca gactttaaggagttttactctgaatccaacatcaaccacgaagggctagagtgtctgcgg ctgctcaacgagataatagccgattttgatgagctgctctccaagcccaagttcagtgga gtggagaagatcaaaaccatcggcagcacctacatggcagccacaggtttaaacgccacc tctgggcaggatgcacaacaggatgctgagcggagctgcagccatcttggcaccatggtg gaatttgcggtggccctggggtctaagctggatgtcatcaacaagcactcgttcaacaac ttccgtctgcgtgtaggattgaaccatggaccagtagtggctggagtgattggggcccag aagccacaatatgacatttggggcaacacagtgaatgtggccagccgcatggagagtaca ggagtccttggcaagatccaagtgactgaggaaacagcccgggccctacagtccctgggc tacacctgctacagccgaggtgtcatcaaggtcaaaggcaaagggcagctctgcacctac tttctgaacacagacttgatacgaactggacctccctcggccactctaggctga

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