KEGG   Carlito syrichta (Philippine tarsier): 103272968
Entry
103272968         CDS       T07836                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X5
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
csyr  Carlito syrichta (Philippine tarsier)
Pathway
csyr01522  Endocrine resistance
csyr04010  MAPK signaling pathway
csyr04012  ErbB signaling pathway
csyr04014  Ras signaling pathway
csyr04024  cAMP signaling pathway
csyr04068  FoxO signaling pathway
csyr04071  Sphingolipid signaling pathway
csyr04137  Mitophagy - animal
csyr04140  Autophagy - animal
csyr04141  Protein processing in endoplasmic reticulum
csyr04210  Apoptosis
csyr04215  Apoptosis - multiple species
csyr04217  Necroptosis
csyr04310  Wnt signaling pathway
csyr04380  Osteoclast differentiation
csyr04510  Focal adhesion
csyr04530  Tight junction
csyr04620  Toll-like receptor signaling pathway
csyr04621  NOD-like receptor signaling pathway
csyr04622  RIG-I-like receptor signaling pathway
csyr04625  C-type lectin receptor signaling pathway
csyr04657  IL-17 signaling pathway
csyr04658  Th1 and Th2 cell differentiation
csyr04659  Th17 cell differentiation
csyr04660  T cell receptor signaling pathway
csyr04664  Fc epsilon RI signaling pathway
csyr04668  TNF signaling pathway
csyr04722  Neurotrophin signaling pathway
csyr04723  Retrograde endocannabinoid signaling
csyr04728  Dopaminergic synapse
csyr04750  Inflammatory mediator regulation of TRP channels
csyr04910  Insulin signaling pathway
csyr04912  GnRH signaling pathway
csyr04914  Progesterone-mediated oocyte maturation
csyr04917  Prolactin signaling pathway
csyr04920  Adipocytokine signaling pathway
csyr04926  Relaxin signaling pathway
csyr04930  Type II diabetes mellitus
csyr04931  Insulin resistance
csyr04932  Non-alcoholic fatty liver disease
csyr04933  AGE-RAGE signaling pathway in diabetic complications
csyr04935  Growth hormone synthesis, secretion and action
csyr04936  Alcoholic liver disease
csyr05010  Alzheimer disease
csyr05012  Parkinson disease
csyr05016  Huntington disease
csyr05017  Spinocerebellar ataxia
csyr05020  Prion disease
csyr05022  Pathways of neurodegeneration - multiple diseases
csyr05132  Salmonella infection
csyr05133  Pertussis
csyr05135  Yersinia infection
csyr05142  Chagas disease
csyr05145  Toxoplasmosis
csyr05152  Tuberculosis
csyr05161  Hepatitis B
csyr05162  Measles
csyr05166  Human T-cell leukemia virus 1 infection
csyr05167  Kaposi sarcoma-associated herpesvirus infection
csyr05169  Epstein-Barr virus infection
csyr05170  Human immunodeficiency virus 1 infection
csyr05171  Coronavirus disease - COVID-19
csyr05200  Pathways in cancer
csyr05208  Chemical carcinogenesis - reactive oxygen species
csyr05210  Colorectal cancer
csyr05212  Pancreatic cancer
csyr05231  Choline metabolism in cancer
csyr05415  Diabetic cardiomyopathy
csyr05417  Lipid and atherosclerosis
csyr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:csyr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    103272968 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103272968 (MAPK8)
   04012 ErbB signaling pathway
    103272968 (MAPK8)
   04014 Ras signaling pathway
    103272968 (MAPK8)
   04310 Wnt signaling pathway
    103272968 (MAPK8)
   04668 TNF signaling pathway
    103272968 (MAPK8)
   04068 FoxO signaling pathway
    103272968 (MAPK8)
   04071 Sphingolipid signaling pathway
    103272968 (MAPK8)
   04024 cAMP signaling pathway
    103272968 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103272968 (MAPK8)
   04137 Mitophagy - animal
    103272968 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    103272968 (MAPK8)
   04215 Apoptosis - multiple species
    103272968 (MAPK8)
   04217 Necroptosis
    103272968 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103272968 (MAPK8)
   04530 Tight junction
    103272968 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103272968 (MAPK8)
   04621 NOD-like receptor signaling pathway
    103272968 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    103272968 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    103272968 (MAPK8)
   04660 T cell receptor signaling pathway
    103272968 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    103272968 (MAPK8)
   04659 Th17 cell differentiation
    103272968 (MAPK8)
   04657 IL-17 signaling pathway
    103272968 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    103272968 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103272968 (MAPK8)
   04920 Adipocytokine signaling pathway
    103272968 (MAPK8)
   04912 GnRH signaling pathway
    103272968 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    103272968 (MAPK8)
   04917 Prolactin signaling pathway
    103272968 (MAPK8)
   04926 Relaxin signaling pathway
    103272968 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    103272968 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    103272968 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    103272968 (MAPK8)
   04722 Neurotrophin signaling pathway
    103272968 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103272968 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103272968 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103272968 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    103272968 (MAPK8)
   05231 Choline metabolism in cancer
    103272968 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103272968 (MAPK8)
   05212 Pancreatic cancer
    103272968 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103272968 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    103272968 (MAPK8)
   05161 Hepatitis B
    103272968 (MAPK8)
   05171 Coronavirus disease - COVID-19
    103272968 (MAPK8)
   05162 Measles
    103272968 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103272968 (MAPK8)
   05169 Epstein-Barr virus infection
    103272968 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103272968 (MAPK8)
   05135 Yersinia infection
    103272968 (MAPK8)
   05133 Pertussis
    103272968 (MAPK8)
   05152 Tuberculosis
    103272968 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103272968 (MAPK8)
   05142 Chagas disease
    103272968 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103272968 (MAPK8)
   05012 Parkinson disease
    103272968 (MAPK8)
   05016 Huntington disease
    103272968 (MAPK8)
   05017 Spinocerebellar ataxia
    103272968 (MAPK8)
   05020 Prion disease
    103272968 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    103272968 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103272968 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    103272968 (MAPK8)
   05415 Diabetic cardiomyopathy
    103272968 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    103272968 (MAPK8)
   04936 Alcoholic liver disease
    103272968 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    103272968 (MAPK8)
   04931 Insulin resistance
    103272968 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103272968 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103272968 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:csyr01001]
    103272968 (MAPK8)
Enzymes [BR:csyr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103272968 (MAPK8)
Protein kinases [BR:csyr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103272968 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH
Other DBs
NCBI-GeneID: 103272968
NCBI-ProteinID: XP_008068621
Ensembl: ENSTSYG00000030731
UniProt: A0A1U7URY8
LinkDB
Position
Unknown
AA seq 384 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLAQVQQ
NT seq 1155 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaatcaaactcatgctaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggtcttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacattgtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctatcttctctatcagatgctgtgcggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaacatagtagtaaaa
tcagactgcactttgaagattcttgattttggtctggccaggactgcaggaacaagtttt
atgatgacgccttacgtggtaactcgctactacagagcacctgaggtcatcctaggcatg
ggctacaaggagaacgtggatttatggtctgtggggtgcattatgggagaaatggtttgc
cacaaaatcctctttccaggaagggactatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcccgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggttatagatgcatctaaaaggatctctgtagatgaagctctccagcacccatat
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgagggcagccttctcctttagca
caggtgcagcagtga

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