KEGG   Carlito syrichta (Philippine tarsier): 103273417
Entry
103273417         CDS       T07836                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
csyr  Carlito syrichta (Philippine tarsier)
Pathway
csyr01521  EGFR tyrosine kinase inhibitor resistance
csyr01522  Endocrine resistance
csyr04012  ErbB signaling pathway
csyr04066  HIF-1 signaling pathway
csyr04140  Autophagy - animal
csyr04150  mTOR signaling pathway
csyr04151  PI3K-Akt signaling pathway
csyr04152  AMPK signaling pathway
csyr04211  Longevity regulating pathway
csyr04213  Longevity regulating pathway - multiple species
csyr04350  TGF-beta signaling pathway
csyr04371  Apelin signaling pathway
csyr04666  Fc gamma R-mediated phagocytosis
csyr04714  Thermogenesis
csyr04910  Insulin signaling pathway
csyr04931  Insulin resistance
csyr05163  Human cytomegalovirus infection
csyr05165  Human papillomavirus infection
csyr05170  Human immunodeficiency virus 1 infection
csyr05200  Pathways in cancer
csyr05205  Proteoglycans in cancer
csyr05207  Chemical carcinogenesis - receptor activation
csyr05210  Colorectal cancer
csyr05212  Pancreatic cancer
csyr05221  Acute myeloid leukemia
csyr05224  Breast cancer
csyr05225  Hepatocellular carcinoma
csyr05226  Gastric cancer
csyr05231  Choline metabolism in cancer
csyr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:csyr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103273417 (RPS6KB1)
   04350 TGF-beta signaling pathway
    103273417 (RPS6KB1)
   04371 Apelin signaling pathway
    103273417 (RPS6KB1)
   04066 HIF-1 signaling pathway
    103273417 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    103273417 (RPS6KB1)
   04152 AMPK signaling pathway
    103273417 (RPS6KB1)
   04150 mTOR signaling pathway
    103273417 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103273417 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    103273417 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103273417 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    103273417 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    103273417 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    103273417 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103273417 (RPS6KB1)
   05205 Proteoglycans in cancer
    103273417 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    103273417 (RPS6KB1)
   05231 Choline metabolism in cancer
    103273417 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103273417 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103273417 (RPS6KB1)
   05212 Pancreatic cancer
    103273417 (RPS6KB1)
   05225 Hepatocellular carcinoma
    103273417 (RPS6KB1)
   05226 Gastric cancer
    103273417 (RPS6KB1)
   05221 Acute myeloid leukemia
    103273417 (RPS6KB1)
   05224 Breast cancer
    103273417 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103273417 (RPS6KB1)
   05163 Human cytomegalovirus infection
    103273417 (RPS6KB1)
   05165 Human papillomavirus infection
    103273417 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    103273417 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103273417 (RPS6KB1)
   01522 Endocrine resistance
    103273417 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:csyr01001]
    103273417 (RPS6KB1)
Enzymes [BR:csyr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     103273417 (RPS6KB1)
Protein kinases [BR:csyr01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   103273417 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 103273417
NCBI-ProteinID: XP_008069034
Ensembl: ENSTSYG00000002384
UniProt: A0A1U7U9T8
LinkDB
Position
Unknown
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgaaggaggcgggacggcttttacccagcgccagacttccgagacagggaa
gctgaggacatggcaggagtatttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagagcggaatattttggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagactggtggaaaactctacctcatccttgagtatctcagtggaggagaacta
tttatgcagttggagagagaggggatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccattcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaagctcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtttgggagctggccct
ggggatgctggagaagttcaggctcatccattctttagacacattaactgggaagaactt
ctggcacggaaggtggagcccccatttaagcctctgttgcaatctgaggaggatgtgagt
cagtttgattccaagtttacacgtcagacacctgttgacagtccagatgactcaactctc
agtgaaagtgccaatcaggtctttctgggttttacatatgtggctccatctgtacttgaa
agtgtgaaagaaaagttttcttttgaaccaaaaatccgatcacctcgaagatttattggc
agcccacgaacacctgtcagcccggtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacagcaaatcctcagacacctgtggaatacccaatggaaacaagtgga
attgaacagatggatgtgacgatgagtggggaagcatcagcaccacttccaatacgacag
cctaactccgggccatacaaaaaacaagcttttcccatgatctccaaacggccagagcac
ctgcgtatgaatctatga

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