Carlito syrichta (Philippine tarsier): 103275280
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Entry
103275280 CDS
T07836
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr00220
Arginine biosynthesis
csyr00330
Arginine and proline metabolism
csyr01100
Metabolic pathways
csyr04020
Calcium signaling pathway
csyr04022
cGMP-PKG signaling pathway
csyr04066
HIF-1 signaling pathway
csyr04071
Sphingolipid signaling pathway
csyr04151
PI3K-Akt signaling pathway
csyr04370
VEGF signaling pathway
csyr04371
Apelin signaling pathway
csyr04611
Platelet activation
csyr04915
Estrogen signaling pathway
csyr04921
Oxytocin signaling pathway
csyr04926
Relaxin signaling pathway
csyr04931
Insulin resistance
csyr04933
AGE-RAGE signaling pathway in diabetic complications
csyr05415
Diabetic cardiomyopathy
csyr05417
Lipid and atherosclerosis
csyr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
103275280 (NOS3)
00330 Arginine and proline metabolism
103275280 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
103275280 (NOS3)
04371 Apelin signaling pathway
103275280 (NOS3)
04066 HIF-1 signaling pathway
103275280 (NOS3)
04020 Calcium signaling pathway
103275280 (NOS3)
04071 Sphingolipid signaling pathway
103275280 (NOS3)
04022 cGMP-PKG signaling pathway
103275280 (NOS3)
04151 PI3K-Akt signaling pathway
103275280 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103275280 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
103275280 (NOS3)
04921 Oxytocin signaling pathway
103275280 (NOS3)
04926 Relaxin signaling pathway
103275280 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103275280 (NOS3)
05418 Fluid shear stress and atherosclerosis
103275280 (NOS3)
05415 Diabetic cardiomyopathy
103275280 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
103275280 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
103275280 (NOS3)
Enzymes [BR:
csyr01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
103275280 (NOS3)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
103275280
NCBI-ProteinID:
XP_008070869
Ensembl:
ENSTSYG00000027211
UniProt:
A0A1U7UF18
LinkDB
All DBs
Position
Unknown
AA seq
1200 aa
AA seq
DB search
MGNLKSVAQEPGPPCGLGLGLGLGLCSKQGPATPASDASRAPATPPPPAPEHSPPLTRPP
EGPRFPRVKNWEVGSIAYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRAPPGPEAPEQL
LSQARAFINQYYSSIKRSGSQAHEQRLQEVEAQVAATGTYQLRESELVFGAKQAWRNAPR
CVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRI
WNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELF
SLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIG
TRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAA
TTSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGS
AAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYASETGRAQGYAQQLGRLFR
KAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRP
EQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAF
ARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAARDI
FSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATILVRL
DTGGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPAPTEPVVVEQLEKGSPGGPPPG
WVRDPRLPPCTLRQALTFFLDITCPPSPQLLRLLSTLAEEPREQQELEALSQDPRRYEEW
KWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEVHLTVAVLAYR
TQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRG
FWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSREPDR
PKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELDEAG
DVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRSAVPWAFDPPVLDTSSP
NT seq
3603 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtggcccaggagcctgggccaccctgcggcctggggctgggg
cttggccttgggctgtgcagcaagcagggcccagccacaccagcctctgatgccagccgg
gccccggcaaccccacccccgccagcaccagaacacagccccccattgacccggcccccg
gaggggcccaggttccctcgtgtgaagaactgggaagtggggagcattgcctatgatacc
ctcagcgcccaggcacagcaggatgggccctgcactccaagacgctgcctgggctccctg
gtatttccacggaaactgcagagtcgggcccccccaggccctgaggcccctgagcagctc
ctgagtcaggccagggccttcatcaaccagtactacagctccatcaagaggagcggctcc
caagcccacgagcagcggcttcaagaggtggaagcccaggtggcagccacaggcacctac
cagcttcgggaaagcgagcttgtgtttggggccaagcaggcctggcgcaatgctccacgc
tgcgtgggccggatccagtgggggaagttgcaggtgttcgatgcccgggattgcaggtct
gcacaagaaatgttcacctacatctgcaatcacatcaagtatgccaccaaccgtggcaac
cttcgttcggccatcacagttttcccgcagcgttgcccgggccgtggagactttcgaatc
tggaacagccagctggtgcgctatgctggctataggcagcaagatggctctgtgcggggg
gacccagccaatgtggaaatcacagagctctgcatccaacatggctggaccccaggaaat
ggccgcttcgacgtgctgcctctgctgctgcaggccccagatgagcctccagagctcttt
tctctgccccccgagctggtcctcgaggtgcccctggagcaccctacgctggagtggttt
gcagccctgggcctgcgctggtatgcactcccagcagtgtccaacatgctgctagaaatt
gggggcctggagttccctgcggcccccttcagcggctggtacatgagcactgagatcggc
acgcggaacttgtgtgaccctcaccgctacaacatcctggaggatgtggctgtctgcatg
gacctggatactcggacaacctcatccctgtggaaagacaaggcagcggtggaaatcaac
ttggctgtgctgcacagttaccagctggccaaagtgacaattgtggaccaccatgccgcc
acaacctccttcatgaaacatctggagaatgagcagaaggccagggggggctgtcctgct
gactgggcctggatcgtgccccctatctcaggcagcctcacccctgtcttccatcaggag
atggtcaactatttcctgtcacctgccttccgctaccagccagacccctggaaggggagt
gcagccaagggcaccggcatcaccaggaagaagacctttaaggaagtggccaacgcagtg
aagatctctgcctcactcatgggcacagtgatggcgaagcgggtgaaggcaacaatcctg
tatgcctccgagaccggccgggcccagggttatgcgcagcagctggggagactcttccgg
aaggctttcgacccccgggtcctgtgcatggatgagtatgatgtggtgtccctcgagcac
gagacgctggtgttggtggtgaccagcacatttggaaatggagatcccccagagaatgga
gagagctttgcagcggcactgatggaaatgtccggaccctacaacagttcccctcggcca
gaacagcacaagagttacaaaatccgcttcaacagtgtctcctgctcagacccgctggtg
tcctcctggcggcggaagagaaaggagtccagtaacacagacagtgcaggggccctgggc
accctcaggttctgtgtattcgggctgggttcccgggcgtacccccacttctgtgccttt
gctcgtgcggtggacacgcggctggaggagttgggcggggagcggctgctgcagctgggc
caaggcgacgagctgtgtggccaggaggaggccttccgtggctgggcccaggccgccttc
caggcctcctgtgagactttctgtgtgggagaggatgccaaggctgctgcccgagacata
ttcagccccaaaaggagctggaagcgccagaggtaccggctgagtgcccaggctgaaggc
ctgcaattactgccaggtctgatccatgtgcacaggcggaagatgttccaggctacaatt
ctctcagtggaaaacttgcaaagcagcaaatccacccgggccacaatcctggtgcgcctg
gacactggcggccaagaggggctgcagtaccagccaggggaccacataggcatctgcccg
cccaaccgtcctggcctcgtggaggcactgctgagccgcgtggaggacccaccagcgcct
actgagccggtggtagtggagcagctggagaaaggcagccctggtggccctccccccggc
tgggtgcgggacccccggctgcctccgtgcacacttcgtcaggctctcaccttcttcctg
gacatcacctgcccgcccagccctcaactccttcgactgctcagcaccctggctgaagag
cccagggaacagcaggagctggaggccctcagccaggacccccggcgctatgaggagtgg
aagtggttccgctgcccaacgctgctggaggtgctggagcaattcccgtcggtggcgctg
cctgcccccctgctcctcacccagctgcccctgctccagccccggtactactcagtcagc
tcagcacccagcgcacacccaggagaggtccacctcaccgtggccgtgctggcatatagg
acccaggatgggctgggccccctgcactatggcgtctgctccacgtggctaagccaactc
aaggccggagaccctgtgccctgcttcatcaggggagctccctccttccggctaccgcct
gatcccagtttgccctgcatcctggtgggcccaggcactggcatcgcacccttccgggga
ttctggcaggagcggctgcacgacattgagagcaaagggctgcagcccgcccctatgact
ttggtgtttgggtgccgatgctcccaactcgaccatctctaccgcgacgaggtgcaggac
gcccagcaacgcggcgtgtttggccgcgtactcaccgccttttcccgggaacctgacagg
cccaagacttatgtacaggacatcctgaggacggagctggcggccgaggtgcaccgcgtg
ctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggcaaccagcgtc
ctgcagacggtacagcgaatcctggcgacggagggcgacatggagctggatgaggccggc
gacgtcatcggcgtgctgcgggatcagcaacgctaccacgaggacattttcgggctcacg
ctgcgcactcaagaggtgacaagtcgcatacgcacgcagagcttttccttgcaggagcgg
cagttgcgcagcgcagtgccctgggcgttcgatccgccggtcctagacacctccagccca
tga
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