KEGG   Carlito syrichta (Philippine tarsier): 7944468
Entry
7944468           CDS       T07836                                 
Symbol
COX1, KEH00_p11
Name
(RefSeq) cytochrome c oxidase subunit I
  KO
K02256  cytochrome c oxidase subunit 1 [EC:7.1.1.9]
Organism
csyr  Carlito syrichta (Philippine tarsier)
Pathway
csyr00190  Oxidative phosphorylation
csyr01100  Metabolic pathways
csyr04260  Cardiac muscle contraction
csyr04714  Thermogenesis
csyr04932  Non-alcoholic fatty liver disease
csyr05010  Alzheimer disease
csyr05012  Parkinson disease
csyr05014  Amyotrophic lateral sclerosis
csyr05016  Huntington disease
csyr05020  Prion disease
csyr05022  Pathways of neurodegeneration - multiple diseases
csyr05208  Chemical carcinogenesis - reactive oxygen species
csyr05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:csyr00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    7944468 (COX1)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    7944468 (COX1)
  09159 Environmental adaptation
   04714 Thermogenesis
    7944468 (COX1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    7944468 (COX1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    7944468 (COX1)
   05012 Parkinson disease
    7944468 (COX1)
   05014 Amyotrophic lateral sclerosis
    7944468 (COX1)
   05016 Huntington disease
    7944468 (COX1)
   05020 Prion disease
    7944468 (COX1)
   05022 Pathways of neurodegeneration - multiple diseases
    7944468 (COX1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    7944468 (COX1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    7944468 (COX1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:csyr03029]
    7944468 (COX1)
Enzymes [BR:csyr01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.9  cytochrome-c oxidase
     7944468 (COX1)
Mitochondrial biogenesis [BR:csyr03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Cytochrome c oxidase
    7944468 (COX1)
SSDB
Motif
Pfam: COX1
Other DBs
NCBI-GeneID: 7944468
NCBI-ProteinID: YP_002929466
UniProt: C4T945
LinkDB
Position
MT
AA seq 513 aa
MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGALLGDDQIYNVVVTA
HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA
GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQ
TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH
PEVYVLILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD
TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLAN
SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGFTLHSTWAKIHFAIMFVG
VNLTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFMIWEAFASKR
EVLAVELPATNLEWLHGCPPPYHTFEEPTYVKA
NT seq 1542 nt   +upstreamnt  +downstreamnt
atgttcattaaccgttgattattctcaactaaccataaagacatcggaactctatactta
ttatttggtgcttgagccggaatagtagggactgcccttagccttcttattcgagcagag
ctcggacagccaggagctctactaggagatgatcaaatctataatgtcgtcgtcactgct
catgctttcgtaataattttctttatagttatacctattataatcggaggcttcggcaac
tgactagtgcctcttataatcggagcccccgacatagcattcccacgaataaacaatata
agcttctggcttctgccaccttctttccttttattattagcctcctcaatagtagaagca
ggcgcaggaactggttgaaccgtatatccccctctagcaggaaacttggcccacgcagga
gcttctgtagatcttactattttctctcttcacttagcaggtgtgtcctctattttaggc
gctattaattttattactaccattatcaatataaaacctcccgctatatcacaataccaa
acccctctatttgtgtgatctgtcctcattaccgcagtcctgctgttattatctctccca
gtcctagcagcaggaattaccatacttctaactgatcgaaatctcaacacaaccttcttt
gaccccgctggcggaggagaccctattctctaccaacacttattttgattcttcggtcat
cctgaagtctatgtccttatcctacctggatttggcataatttcccatatcgtaacctac
tattctgggaagaaagaaccatttggctacataggaatagtttgagcaataatatccatc
ggatttctaggctttattgtctgagcccatcatatgttcacagtaggaatggatgtagac
actcgggcatacttcacatccgctaccataattattgctatcccaactggcgtaaaagta
tttagctgattagctaccctacacggaggtaacatcaaatgatcccccgccatattatga
gctctaggcttcatttttctatttaccgtcgggggtctgaccggaattgtccttgccaac
tcttcactcgacatcgtcctccatgacacctactatgtagtagcacactttcactatgtc
ctgtccataggtgcagtctttgcaattataggaggttttgtccactgattccccttattt
tcaggatttaccctccattcaacatgagccaaaatccacttcgcaattatatttgtagga
gtaaatctaaccttttttcctcaacatttcctcggactatctggcatgccccgccgatac
tcagattacccagatgcatacactatatgaaataccatttcttccataggttcatttatc
tctctaaccgcagttatactaatagtctttataatctgagaagcctttgcttcaaagcga
gaggtattagcagttgaattacctgccacaaaccttgagtgacttcacggctgtccccca
ccttatcacacatttgaagaacctacctacgtaaaagcgtag

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