Clostridium tetani E88: CTC_00728
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Entry
CTC_00728 CDS
T00112
Name
(GenBank) uroporphyrinogen III synthase/methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
ctc
Clostridium tetani E88
Pathway
ctc00860
Porphyrin metabolism
ctc01100
Metabolic pathways
ctc01110
Biosynthesis of secondary metabolites
ctc01120
Microbial metabolism in diverse environments
ctc01240
Biosynthesis of cofactors
Module
ctc_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
ctc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CTC_00728
Enzymes [BR:
ctc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CTC_00728
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CTC_00728
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
MptE-like
SAM_Exu
Motif
Other DBs
NCBI-ProteinID:
AAO35330
UniProt:
Q897K6
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All DBs
Position
753763..755220
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AA seq
485 aa
AA seq
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MGKVYLIGAGPGDEELITLKATRMLQKCTAVMYDRLAGPGFLKYLNEDCEIYYCGKEPGC
HYKTQDEINEMLAKLAKKGHVVGRVKGGDPFIFGRGGEEILRLLEDNIEFEVIPGITSAI
SVPSYAGIPVTHRAIAQGFHVFTGMTAEKLDIDWKAVANVGGTLIFLMGYRNLDIIRNRL
MENGMNENTPCAIIMRGTTSNQKKVVGTLKDISEKAEKQGVTSPCIILIGDVVQFNDKFN
WYEKKRLFGKNICVTRSRVQAKELREKLSDLGAQVTEINAIKIKSRDDELEKYVERLKDY
KFIVLTSVNAVNILFDYLVKKEYDIRNIKGRFAVIGPATEKALLKRGIKADIIAKEFVAE
DLFNELKPYLNKDDKIFVPHSKQARQYLVEALKDKGCHVEEVYSYEVVKGEVPNLEIFDD
VDIVLYTSPSIVRNMIDMIGLEKLKKKTSISIGPITAKELDKNGIDYIICDEYTTDGMIE
KLLTL
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atgggtaaggtatatctaataggggcaggaccaggagatgaagaacttataacattaaaa
gccactagaatgttgcaaaagtgcactgctgttatgtatgacagattagcagggccagga
ttcttaaaatatttaaatgaggattgtgagatttattactgtggtaaggaaccaggttgt
cattataaaactcaagatgagataaatgaaatgcttgcaaagctagctaaaaaaggtcac
gtagttggaagagtaaaaggtggagatccttttatatttggacgtggaggagaagaaata
ttaagacttttagaagataatatagagtttgaagtaataccaggaataacttcagcaata
tccgttccaagctatgctggaattccagtaactcatagagctattgctcaaggttttcat
gtatttacaggaatgacagcagaaaaacttgatatagattggaaagctgttgcaaatgta
gggggaactttaatatttttaatgggttatagaaatttagatataattcgcaatagatta
atggaaaatggaatgaatgaaaatactccttgtgcaattataatgagaggaactacttct
aatcaaaaaaaggtagtgggtactttaaaagatatttcagaaaaagcagagaaacaaggt
gtaacttctccttgtataatactaattggagatgtagtacaatttaatgataaatttaat
tggtatgaaaagaaaagactttttggcaaaaatatatgtgtaactcgttcaagagttcag
gcaaaagaattaagagaaaagttatcagatttaggagcacaggttacagagataaatgct
atcaaaataaaaagtagagacgatgagttagaaaaatatgtagaaagattaaaagattat
aaatttatagttttaacaagtgtaaatgcggtaaatatacttttcgattatctagtaaaa
aaagaatatgatataagaaatataaaaggaagatttgcagtaatagggcctgcaacagaa
aaagcattattaaaaagaggtataaaagcggatataattgctaaagagtttgtagcggaa
gatttatttaatgaattaaaaccttatttaaataaggatgataaaatatttgtacctcat
tctaaacaagctagacagtatttagtagaagccctaaaagataaagggtgccatgtagaa
gaagtctatagttatgaagtggttaaaggagaagttcctaatttagaaatatttgatgat
gtagatatagttttatatactagtccaagtatagttagaaacatgatagatatgataggt
ttagaaaaacttaagaaaaagacttcaatatccataggacctataacagccaaggaacta
gataaaaatggtatagattatattatctgtgatgaatatactacagatggaatgatagaa
aaacttttaactttataa
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