Acetivibrio thermocellus ATCC 27405: Cthe_0977
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Entry
Cthe_0977 CDS
T00474
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cth
Acetivibrio thermocellus ATCC 27405
Pathway
cth00300
Lysine biosynthesis
cth00550
Peptidoglycan biosynthesis
cth01100
Metabolic pathways
cth01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cth00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Cthe_0977
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Cthe_0977
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Cthe_0977
Enzymes [BR:
cth01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Cthe_0977
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABN52209
UniProt:
A3DE30
LinkDB
All DBs
Position
complement(1167087..1168460)
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AA seq
457 aa
AA seq
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MEILKCEEVVKAVGGTLISGEVNTVFYNISTDSRNIKQGDLFIPLIGERFDGHNYIASAL
EHGALGSLTQKETEPFPGKVLIKVSDTLKALRDLAVYYRQKFKIPFVGITGSVGKTSTKE
MVAAVLSKGFKVLKNQGNFNNEIGVPLTIFNLDKSHEAAVVEMGMSGFGEISRLTSIVKP
DIAIITNIGVSHIEKLGSKNNILKAKMEIFEGLNEKGLAILNGDDKLLYGLNNLLKFRTV
FYGMEEGLDLRAYNVESLGEKGSTFDIEIRGKEYRVRIPVPGIHNVYNALAGIAVGIELG
IPPEKIVEGIEEFSPGKMRLDIINYNGLKIINDAYNASPQSMEAAIDVLKDISGEGRTFA
VLGDMLELGEFSKSAHMEVGKYAASKGIDYIVAVGEYRSNIVRGAVEAGAKEEKVFEFKD
NMDAAKFLKEFVKSGDVLLVKGSRGMKMEEIVNILTG
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atggaaattttaaaatgcgaagaagtagtaaaagcggttggcggcactttaatatccgga
gaagtcaatactgttttttataacatttccaccgattcgaggaatataaaacagggagat
ttgtttattcctcttattggagaaagatttgacggacacaactatattgcgtctgctttg
gagcatggagctctgggcagccttactcaaaaggaaacggaaccatttcccggcaaagtt
ttaataaaggtttcggatacacttaaggctttaagggatcttgcggtgtattacagacaa
aaattcaagatcccttttgtaggaattaccggaagtgtggggaaaacaagcaccaaggaa
atggttgcggcagtgctgtcaaaaggcttcaaggtgctgaagaaccagggtaattttaac
aatgaaatcggtgtgcctcttacaattttcaaccttgacaaatcccacgaggctgccgtt
gtggaaatgggcatgagcggttttggcgaaataagccgtcttacgtctatagtaaaacct
gatattgcaataataaccaatataggagtatcccatatagaaaagctgggttcaaaaaat
aacatattaaaagcaaaaatggagatttttgagggcttaaatgagaaaggattggcaata
ctaaatggtgatgacaaattattgtatggattaaacaaccttttgaagttcaggacggta
ttttacggaatggaggaagggctggatttgcgggcatacaatgtggaatctttgggggaa
aaaggctccacttttgatattgagattagaggaaaagaatacagggtgagaattcctgtg
ccgggaattcataatgtttacaatgcccttgcaggtatagcagtgggaattgagcttgga
ataccgccggagaaaatagttgagggaattgaagagttttccccgggaaagatgagactt
gatattataaactataacggtttaaagattataaacgatgcttacaatgcaagtccccag
tcaatggaggcggctattgacgttttaaaggatatatccggtgaaggcagaacctttgcc
gtattgggtgacatgcttgagctgggggaattctctaaaagtgctcatatggaagtggga
aaatatgctgcttcaaaagggatagattatattgtggccgtgggagagtacagaagtaat
attgtccgtggtgccgttgaagcaggagcaaaagaagaaaaggtttttgaatttaaagac
aatatggatgccgcaaagtttttaaaagaatttgtaaagagcggtgatgtgcttcttgta
aagggttcgagaggtatgaaaatggaggaaatagttaatatattgactggctga
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