Acetivibrio thermocellus ATCC 27405: Cthe_2519
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Entry
Cthe_2519 CDS
T00474
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
cth
Acetivibrio thermocellus ATCC 27405
Pathway
cth00290
Valine, leucine and isoleucine biosynthesis
cth00620
Pyruvate metabolism
cth01100
Metabolic pathways
cth01110
Biosynthesis of secondary metabolites
cth01210
2-Oxocarboxylic acid metabolism
cth01230
Biosynthesis of amino acids
Module
cth_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
cth00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Cthe_2519
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Cthe_2519
Enzymes [BR:
cth01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Cthe_2519
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ABN53721
UniProt:
A3DIE2
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All DBs
Position
2987849..2989468
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AA seq
539 aa
AA seq
DB search
MGIVKHFFRKDEKMKKILIYDSTLRDGAQAQGISFSVEDKLKIVERLDRLGISYIEAGNP
GSNPKDLEFFDRIGRVKLRHAKIIAFGSTRRVNVSVQEDANVKSLLKADTPAVAIFGKSW
DFHVTDILKTTLDENLRMIFDTISFFKNKNKEVVFDAEHFFDGYKANPDYAMKTLKTAVE
AGADCICLCDTNGGTFPNEIKDITARVVSEFNVNVGIHCHNDTGMAVANSIMAVLAGAVQ
VQGTMNGFGERSGNANLCTIIPNLQLKAGYDCIPQENMADLTATARSISEIANVIHDERA
PYVGKYAFAHKAGMHADAVTKNSIAYEHINPEVVGNERLFLMSEVAGRSAVLHLIKNIDS
TITKDSPETKLILDKLKELEFEGYQYEGAESSFEIVIRKILGKYRPSFELGEFKVVVNEP
SISGANSSAMIKINVDGQYEITADEGQGPVNALDKALRKALEKFYPQIAEMKLTDYKVRV
LDSNSATAAKVRVLIESTDGKEVWTTIGVSTDIIEASWKALVDSIEYKLIKDKEAKQKS
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
ttgggaattgtaaagcattttttcaggaaggatgaaaagatgaagaagattttgatatat
gactctaccttaagggatggtgcccaggcacagggtatttcgttcagtgttgaagataaa
ctgaaaattgtggagagacttgaccggctcggtataagctatattgaagcaggtaacccg
ggctccaacccaaaggatttggagttttttgacagaatagggcgggtcaagttaaggcat
gcaaaaataatcgcctttggaagtaccagaagagtcaatgtaagtgttcaggaggatgcc
aatgtaaaatcgcttttaaaggcggacactccggctgtggccatattcggcaaaagctgg
gactttcatgttaccgatattttaaagacaacactggatgaaaatttgagaatgattttt
gacaccatatccttctttaagaacaaaaataaagaagtggtttttgatgctgagcatttc
tttgacggatacaaggccaacccggattatgcaatgaaaaccctcaaaactgctgttgag
gccggagcggactgtatttgcctttgcgataccaatggaggaacattcccgaatgaaatc
aaggatattaccgccagggttgtgagcgagtttaacgtgaatgtcggtattcattgccac
aatgacacgggcatggcggttgccaactccattatggcggtgctggccggtgccgtgcag
gttcaggggacaatgaacgggtttggagagagaagcggtaatgccaatctctgcacaata
atacccaatttgcagcttaaagcaggctatgattgcataccgcaggaaaacatggcggac
cttacggctactgcaaggtccataagtgaaattgccaatgttatacatgatgaaagggct
ccgtatgtagggaaatatgcatttgcccacaaggcgggaatgcatgcggatgcggtaacc
aaaaactccatagcttacgaacacatcaaccctgaagttgtcggaaacgaaaggcttttt
ctcatgtcggaagttgcgggaagaagcgctgtgcttcatttaatcaaaaatattgacagc
actattacaaaggattctcccgagacaaaattgatactggacaagctcaaggagctggaa
tttgaaggctatcagtacgaaggtgcggagagttcttttgaaattgtgattcggaaaatc
cttggaaaataccgtccttcctttgaacttggagagtttaaggttgtggttaacgaaccg
tctattagcggtgcgaattcttccgccatgataaagattaatgtggacggacagtatgag
ataaccgcggatgagggacagggtccggtaaatgcgctggacaaggcgctaagaaaggct
ttggagaaattttatcctcagattgcggaaatgaagcttaccgactacaaagttagggtt
cttgattccaactcggctacggctgcaaaggtaagggttttaattgagtcaaccgacggt
aaagaagtctggacaaccattggagtttcaacggacattattgaagccagctggaaggcg
ttggtggattctatagaatacaagcttatcaaggacaaggaagcaaaacaaaagtcttaa
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