Crotalus tigris (Tiger rattlesnake): 120314490 Help Entry 120314490         CDS       T08476                                  Symbol HMCN1 Name (RefSeq) hemicentin-1 isoform X1   KO K17341   hemicentin Organism ctig  Crotalus tigris (Tiger rattlesnake) Brite KEGG Orthology (KO) [BR:ctig00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:ctig04990]     120314490 (HMCN1) Domain-containing proteins not elsewhere classified [BR:ctig04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    120314490 (HMCN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 Ig_5 EGF_CA VWA_4 TSP_1 G2F cEGF Ig_6 V-set_CD47 C2-set_3 Receptor_2B4 TSP1_spondin C1-set GBD_Hemicentin EGF_3 FXa_inhibition TSP1_CFP_C TSP1_ADAMTS TSP1_CCN VWA7_4 Motif Other DBs NCBI-GeneID:  120314490 NCBI-ProteinID:  XP_039213554 LinkDB All DBs Position Unknown AA seq 5592 aa AA seqDB search MDFHDNVPLRAVGFCASFFFVLLVSFTCAQNGVVESEPTLEEIPQGASTLAFVFDVTGSM YDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPEIGPITITADPKKFQYELRELYV QGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYKLTHEVLQLIQQKQSQIVFVLT GDCDDRTHTGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTSG ESFWQIPFDPSLKEVTVSLSGPSPEIEIHNPLGKHVKKGSGLNELLNIENSAKVVNIKEP EPGTWSIQISSSGRHSIRITGLSNIDFRAGFSRKPTLDFKMTSTRPVQGIPTYILLNTTG IHLPARVDRLELLSITGEPLKTVPVKPFPESNPYGIWNISEFIPPNEAFFLKITGYDKND YLFQRVSSVSFSNIIPDAPKVSMPKKTPGYYLQPSRISCHIASLIPFTAHFKRNGVKLGM DQFFKESAIVSWEIAKVTLLDEGYYECIASSTAGTGHAETFLDVSEPPPVIQVPNNVIVP PGARAILTCLTMSTVRYNLTWHRDNRNVKFLEPLRMRIMSNLSLELKTVKISDAGEYNCM ASNEGGFTRASVFLTVQESPKVIVSPKNQSFTEGSEVSISCSATGYPKPTVVWTHNDIFL MASNRYRLTPGGTLMIKNAVPKDEGVYGCLASNAAGTVKETAVLIYIEFPRVTVVQNELL IALGDTSIMECKSTGVPPPLIKWFKGDLELRATEFLIIDFSRGTLRIQETQDLDAGDYMC VATNVAGTASDKITLDVGSPPVFTQEPSDVSMDIGSNITLACYVQGYPEPKVKWQRLDGS PLFSRHFAVSSVSQLRTGALSIHNLWVNDEGTYVCEAENQFGKIISSPATVTVTGLVAPL IARSPATANVIEGQQLTLSCVLLAGNPIPERKWIKSSTVVVQTPYISLWSDGSLHLERVR LQDAGDYSCMASNVAGTDNKTTTVNVFVPPIIQHGQQIFSTIEDVPLTLPCKASGVPKPS IVWSKKGEMIPPSSSMFSAGSDGSLYVVSPGGEESGEYICSATNAAGYTARKVQLTVYVK PRISRPGSQQGSSLDNPIEMSVTAGEEVTLPCEAKSLPPPIISWAKEMQLISPFSPRHTL LSSGSMKITETWVSDSGLYICVVTNIAGNATQKIKLNVHVPPKIQHGPRVIKAKVNNRVD IHCNAQGIPSPRITWLKDQQSILIDNRQYAASLDGTLSIIKVVLSDAGIYKCMASNIAGH DEAEIMIQVQEPPSVGALDPPYNSPFQERVAKEQIAFPCPIKGTPKPVIKWLHNNREITG NEPGLSILEDGTLLVIASATPYNSGEYICTAINEAGNTEINYSLKVYVPPEIKDQDKVTN ASVAINKPLGLFCEVSGDPFPVITWYKDDVQVLEGSTLQILENGKLLKLLKVATDDAGQY SCKATSIAGSSEKFFTVDVQVPPIIGDAESNEFSVTLSQQAILECRVSGSPFPIIKWSKD GKPLFLGDPNIEVLDKGQILQIKSTQRVDKGRYQCSATNSAGKQFKELKLIIHIPPTIKG ENITTEVSELLHSILKLECEVRGIPAPTITWYKDGSPIISGPQAVYLEHGQFLQIPHAQV SDSAQYTCQATNEAGVAEKIFQVDVYVPPIIEGVSETIQNKQVVVGSSLMLECNAAGNPP PLLTWLKNGVPVTASDYLHVVSSGKKLEILNAAVTDHGQYMCVATSIAGEQEIKYDVEIL VPPSLEGGDESSGHTVILHSNLELECPAIGTPLPTITWLKNGQPIEGGVGYKLLLNGRRL LISRAEVSDAGHYQCIATNKAGETKQEFDVIVHVSPTIKMSGPSERFVVIHKPVTLQCIV NGIPIPSITWLKDNQPVNTARENIGLESSGHILQIAKALKYDAGRYTCIATNAAGEAQQS IYLHVYEPPSLKDAGMLRNETVIVNNPIQLVCRVSGTPLPVVTWYKNNLPLINIAGITFL NRGQIAQIDAAQISDTGIYKCAVTNAAGVAELFYNLQVHVPPSISGNNEMVTVVVNDQVR LECEARGIPAPILTWLKDGSPVSSLSSGLQIRSGGRILALTSAQISDTGRYTCVAVNAAG EKQRDIDLRVYVPPNIMGEEQNVSVAMGEHLELRCQSNAIPPPMLQWLKDGQLLQKKLGL TITEGGSILKIAQAQVQDTGRYTCEATNIAGKMEKNYNVNIWVPSSIYSSDTVTQLTVIE GNLISMMCESRGIPPPTLAWRKNGSPLVVDPTGRVRVLSGGRQLQISIAEKSDSASYTCI ASNVAGITKKEYKLLVYVHPTILDNGNIQSDVIVTQGNDISFECQVDGIPQPTVTWMKDG QPLANERGVEILNEGHSLRLKSAQVSDTGRYVCVAVNVAGLTDKKYDLSVHVPPRIMGNL VQPENVSAVEKSPVNLICESSGIPHPSIMWLKNGQPVSLSNSVRILSGGRMLRLMQVKME DAGHYICVVNNIAGEDRKNFELSVLVPPSIVGENKLEDVKVKEGHGITLTCEVTGNPIPE ITWLKDGQTFLQDDGYQLMSSGRFLQITNALVADTGRYTCVASNTAGDKRKSFSVNVLVS PSIVGADNNGGAEEATVILNNPTSLVCEAYSYPPATITWLKDGAPIDSNENIRVLPGGRT LQILNAQEDNTGRYTCIATNEAGETLKHYEVKVYIPPTISRDNLSGLGLSPKEVKIRVNN SLTLECEVHAIPAAGIRWYKDRQLITSDDHLTIQGGGRILQIKATQISDTGRYSCVASNL AGEDELEFDVNIQVPPSFRKPFGFWEDGDALSRRQRGRAKDVIVNYPLSLYCETNAVPPP VLTWYKEDFPLSSNDKVRILPGGRVLQISRAQSEDAGRYTCVATNEAGEDSIQYDVRVLL PPSINGANGDVTEELTVLLDKMAMMECIAEGIPPSSIIWEKDGQLIAEDSHYKFQLGGKT LQIHNTQIANTGRYVCLVENIAGRAKRYFNLNVHVPPNIIGINPENLTVVVNNFISLTCE VTGFPPPDLSWLKDGKPLSLNTNILIVPGGHTLQIPKAHLSDGGQYVCIARNSAGESIKR TFLTVYVPPSIKGESSTPPAIVNVRVGMPVTLECESNAVPPPIITWYKNGRIISVSSNVG FIADGQTLHIKMTEVSDTGQYVCKAINIAGRDDKTFHLNVHVLPTIEGPQQEWINETISN PITLTCDATGIPPPAITWLKNGKPLENSATHELHILSGGNKLQITRPHYSDTGNYSCIAS NVEGKAQKFYVLSVEIPPDIVGSEMPSEVSGILGENIQISCEASGIPTPVIQWLKDGKPI SNGESQQISMVPNGSLLNIFGALTSDGGKYSCVATNPAGEEDRIFSVNIYVPPTISKNKE EPEALTVVLDTSINIECQSMGTPPAQINWLKNGLPLSISSHIRLLSAGQVLRIVKAQVAD VGVYTCIASNRAGVDNKHYSLQVYVPPSIDNGGETEEVTVLKGNPVSLVCLANGIPTPTI SWLKDGQTLSSNFHVTFENQKMGLRILNSEVNDTGRYTCIASNEAGEDNQHFILKVLEPP HINKSDNPEEISTVINNPLELLCISDGIPIPKLTWMKDGRPLHQADTVHVLRGGQVFRIS SVQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTSNSQNLSVLQNQQVILECKSDA VPPPVLTWLKDGEILEATRRVRILSSGRYLQINNADLNDAANYTCVASNVAGRTTRTFVL DVNVPPSIKNGSQTVIVNINMSAVLECAVEGVPVPRISWRKDGALLAGHNVRHSLLGNGS LHIHSAQVTDTGRYLCMATNVAGTERKRIDLQVHISPYIAPGPVNVTVSVNIQTTLPCET TGIPKPAIAWKKNGHVLNLDQNSFRLLSSGSLVIFSPSVEDTALYECIVTNEAGKDQRTI SLMVEVPPSIADEVTDLLVTKSSPIIIPCTASGVPVPSILWTKNGIKLPSRGNGFRILSS GAIDISTAQLDHSGKYTCTAWNAAGSAYRHITLLVQGEVGTKPPTIRMQPGALAVILNNP VLLPCKASGTPHPVISWQKEGVSVITTGNRYTVLPNGSLQIAKVAVEDAGTYMCVAQNPS GTALGKIKLKIQVPPVIKSHPREYVIIMDKPVTLLCEAEGYPTPLIAWQKNEQIITESMR RRVLSTGGLQIAFVQPMDTGHYTCNATNAAGSSSSSMELTVLVPPKIHAVEDHYTVVENS QAVLSCVADGMPAPSVTWRKGDTSLVAKRSSESHGDFIIEKAKPEDSGSYTCIANNVAGE DTHTISLTVYVLPAFTELPGDVALNKGEQLQLNCKATGVPVPNIKWIFNNNIIPAQYDGV NGLSKLVIERVSKKDSGTYVCMAENLVGSIKALGSVYVKEPPVFMGHDHSSRIEPLGGNA ILNCEVTGDPPPTIQWSRKGVGTLISNRIRQLSNGSLVIYGTVNEDAAEYICIATNDAGV VEHHVTLTLHSTPVIKTEPAEITVDAGTTAVLNCQAEGEPHPTIEWSRQGWPLLNQDRMT VLSNGSLRIAVAHKEDTSEYECVARNLMGSVLVKVPFIVQVHGGFSQWLDWQLCSVTCGR GVQKRIRLCNNPFPANGGRSCMEPDYELRSCQSKLCPVDASWSEWGSWEECSKACGQGNK TRTRSCSNPSAQHGGRPCEGNAVESTVCNIRPCPVNGKWTSWSSWSACTMSCGGGAQQRT RDCSDPPPKNGGLRCEGNDLQVGFCNTDLCPTHGNWGPWSNWGTCSRTCNGGHTRRYRIC DNPHPLNGGRACVGADTQTQRCRGELCPVNGNWGPWQPWSACSASCGAGEKIRSRLCNNP PVSNNGRLCPGDEAQISRCNIQACPGGPSHARGSVIGHINDVEFGIAFLNATIIDGPDED ITSVEAKITNIPRNLGPVMKVLVSILSPIYWITAKEIGEAVNGFSLTSAVFKRETQVEFA TGELLRMTHVARGLDSDGSLLLDVVISGHILQLQSTDDVNVKDYTEDYIQTGPGQLYAYS TRLFSIDSVSIPYTWNHTITYNQNRGKMPSLVETLQASSIKTEYSPHEEALTFKIDASIT KGDHSNQCPHGFSLDSSGPYCSDEDECITQKPCPHICHNVVGTYYCSCPKGLTISADGRA CQDIDECALARHSCLVGQDCENIIGSYRCVIQCGIGFRRTPDGLSCQDVNECQESHPCHQ HCFNSIGSFHCGCDPGYQLKGRKCMDVNECRQNVCRPDQLCKNTRGGYKCIDLCPSGMTK AENGTCIDIDECRDGTHQCRYNQLCENSKGSYRCVCPRGYRYQGVGRPCMDINECEQVPK PCAYQCANIPGSFKCICPPGQHLLGDGKSCAGLERFPNYGTYYNSYNYAQFSPMRDNYRP QQYIRHSSNLYSSYSEYRNSRIPISRTRRNVREPCPEGYEARNNKCVDIDECENRGVCQH ECRNTLGSYQCFCPSGYRTMPNGKTCQDIDECLEQNIYCGPNRMCFNMKGSYQCVETPCP PHYERDLLSGSCLKKCRPNDLECALSPYALEYKLVSLPFGIAANQDLIRLVAYTEDGVMH PRTSFLMVNKEDMSIPFSLRDENLKGVVYTTRPLLEPETYRMRVRALSYSSDGAIEYQMT FIVYIAVSAYPY NT seq 16779 nt NT seq  +upstreamnt  +downstreamnt atggatttccatgacaatgtccccctgcgggccgtaggattctgtgcatcattctttttt gtcctccttgtttcatttacctgtgcccaaaatggagtagtagaatctgaacccaccctg gaagaaatcccacaaggcgcatctaccttggcttttgtatttgacgtgactggctcaatg tacgatgacttagttcaggtcattgaaggtgcctccaaaattttggaaacctctttgaag agacccaagaggccactttacaactttgcattagttcccttccatgatccagaaattggt cctataaccattaccgcagatcctaagaaatttcaatatgaactcagagaattatatgtt cagggaggtggtgactgtccagagatgagcattggggccatcaaaattgctctagaaatt tctcttcctggttcattcatctatgtatttactgatgcccggtccaaagattataaactg actcatgaggtcttgcagctcattcagcagaagcagtcccagattgtatttgttctaacc ggagactgtgatgacagaacacatactggttataaagtctatgaagagattgcttcaaca agttctggtcaagtttttcacttggataaaaagcaagttaatgaggtactgaaatgggtg gaagaagcagtgcaagcttctaaagttcatctattgtctacagaccatttaacttcagga gaaagcttttggcagatcccttttgatcctagtctgaaagaagttacagtgtcactaagt ggtccttccccagaaattgaaattcacaaccctttgggtaagcatgtaaagaaaggatct ggcttgaatgaattactcaatattgaaaattctgctaaagtagtgaacataaaagaacca gaaccaggaacatggtctattcagatatcaagtagtggacgacactctattcgtatcact ggacttagcaatattgacttcagagctggattttccaggaagccaacactagacttcaaa atgacttctaccagaccagtacaagggatacctacctacattctgctcaatactacaggg atccatcttccagctagagtagatcgtttagaactgctgagcatcactggagagcccctc aagactgttcctgtaaaaccctttcctgaaagcaatccttatggaatctggaatatctct gaatttattccaccaaatgaagccttcttccttaaaataactggctacgacaaaaatgat tacctctttcagagagtttcaagtgtttcattttctaatattattcctgatgctccaaaa gtcagcatgcccaagaaaaccccaggatattatctgcagccaagtcgtatttcttgtcat atagccagcctcattccttttactgctcattttaaaagaaatggagttaaactgggaatg gatcagtttttcaaagaatctgctattgtaagttgggaaattgccaaagtaactcttttg gatgagggctattatgaatgcatcgctagcagtactgcaggaacaggacatgcagagaca tttttggatgtatcagaacccccacctgtcatacaagttcctaacaatgttattgtccct cctggtgccagagccattcttacatgcttaactatgagcacagtgcgttacaatctcacc tggcacagagataataggaatgtgaaattcctggagcccttgagaatgcgaataatgagc aatctctctctcgaactcaaaaccgtcaaaatctcagatgccggagagtacaactgtatg gcttctaatgaaggtggtttcaccagggcatctgtattccttacagtgcaagaatcaccc aaagttattgtatcacccaagaaccaatcatttactgaaggatctgaagtgtctatcagt tgctctgcaacaggttacccaaagcccactgtggtgtggacacataatgatatctttctt atggcatccaacaggtacaggttaactcctggaggtactttaatgataaaaaatgcagtt cccaaggatgaaggggtctatggttgcttggctagcaatgcagctggaacagtcaaagaa acagctgttctcatatacattgagttccctcgggtgactgtagtacaaaatgaacttctg attgcccttggagacacctctataatggaatgcaaaagcactggggtcccacctccgtta attaaatggtttaaaggggatttagagctgagggcaacagaatttcttattattgacttc tctcggggtaccctgagaattcaggaaacacaagatctggatgctggtgattatatgtgt gttgccacaaatgttgcaggaactgcatctgataaaataactctggatgttggctctcct ccagttttcacacaagaacctagtgatgtatctatggatattggctcaaacataacattg gcttgctatgttcagggttatccagaaccgaaggtgaagtggcagcggttggatggcagc ccacttttctcaagacattttgcagttagctctgtcagtcaactcagaacaggagccctt tctattcacaatttatgggttaatgatgaaggaacatatgtctgtgaagctgaaaaccag tttggaaagattatctcaagcccagctacagttactgtgacaggacttgttgcacctcta attgcaaggagtcctgcaacagctaatgtcattgaaggacagcaactgactctgtcatgt gtactgctggcagggaacccaatcccagagcggaaatggattaaaagtagcacggtggtg gtccagactccttatatcagcctctggagtgatgggagtcttcatcttgaaagagttcga ctacaggatgctggagactacagttgcatggccagcaatgttgctgggacagacaacaaa acaaccactgtcaatgtctttgttccacccataatccagcatggacaacagatatttagt actatagaagatgttccacttacattgccttgcaaagccagtggagttcctaagccatcc atagtatggtccaagaaaggagaaatgattcctcccagtagttcaatgttttctgctggg tctgatggaagtctttatgtagtttctccgggaggtgaggagtctggggaatacatctgc agtgcaaccaatgcagcaggttatactgcacggaaagtacaactgacagtctatgtaaaa ccaagaatttccagacctggaagtcagcaaggaagttcactagataacccaattgagatg tcagtaacagctggggaagaagtgacacttccctgtgaagcgaaaagtttgccaccccca ataatctcttgggctaaagaaatgcagcttatttctccattttctccaagacatacctta ctctcttcaggctcaatgaagatcacagagacgtgggtatcagacagtggcttgtacatc tgtgtggtcacaaatattgctggaaatgcaacccaaaaaataaaactaaatgtacatgtt cctccaaagatacaacatgggcctcgagtgattaaagcaaaagttaataatagagttgat atacattgcaatgctcaaggaatcccatctccaagaattacttggcttaaagatcaacaa tccattttgatagacaacagacagtatgctgcttctctagatggaacactgagtatcatc aaagttgtgctttcggatgctgggatctataaatgcatggcaagtaacattgctggccat gatgaagctgagataatgatccaagttcaagaacctccaagtgttggagcacttgatcca ccatacaactctccatttcaagaaagagtagcaaaagaacaaattgccttcccatgccca atcaaaggtactccaaaacctgtgataaaatggctacataacaatagggagattacgggc aatgaacctgggctttcaattttggaagatggaactttgctggtcattgcttccgccaca ccatacaacagtggagaatatatctgcaccgcaatcaatgaagctggaaacacagaaata aactacagtctgaaagtttatgttccacctgaaatcaaagatcaggacaaggtgaccaat gcatctgtggccatcaataagcctttaggtctgttctgtgaggtatctggtgatcctttt ccagtcattacttggtataaagatgatgtgcaggttctggagggaagtactttgcaaatt ttggaaaatggaaagttgttgaaacttcttaaagttgcaactgatgatgctggccagtat tcatgtaaagccaccagtatagctgggagttcagagaaatttttcactgtagatgtgcaa gtcccacccattataggagatgctgaatccaatgaattttcagtcaccctcagccaacag gcaattttagaatgcagggtcagtgggtctccttttcctatcatcaagtggtccaaagat ggcaagcccctctttttaggtgaccctaatattgaggttttggacaaagggcaaattctt caaataaagagtactcaaagagttgacaaaggacgctaccaatgcagtgcaaccaattct gcaggcaaacagtttaaggaactcaaactcataatccacattccacctacaattaaagga gaaaatattaccactgaggtgtcagaattgctacatagcatcttaaagctggagtgtgaa gtcagaggaattccagctcctacaataacatggtataaagatggaagcccaattatttct ggtccccaagctgtttatttggaacatggacaatttctccagattcctcatgctcaagtc tctgattcggctcaatatacctgccaggctaccaatgaagctggggtggctgaaaaaata ttccaagtggatgtctatgtacccccaattattgagggtgtcagtgaaaccattcaaaac aagcaagtggttgttggaagttcacttatgttggaatgtaatgctgctggcaaccctcct cccctgttaacctggctgaagaatggagttcctgtaacagcaagtgactacctccatgtt gtgtccagtgggaagaagctggagatcctgaatgctgctgtgactgaccatggccaatat atgtgtgtagctactagcatagctggggaacaggagatcaaatatgatgtggaaatccta gttccaccaagtttggaaggaggagatgaatcttcaggccacactgtgattctccacagc aacctagagttggaatgtccagccataggaacacccctgccgaccatcacatggttgaaa aatggccaacctattgaaggaggagttggatataaacttttgctcaatggacgcaggctt ctcatctctcgggctgaagtatctgatgcaggccattatcagtgtatagcgaccaacaag gcgggagaaaccaaacaagaatttgatgtgattgtgcacgtctctccaacaatcaaaatg agtggtccttctgaaagatttgtagtgatacacaaaccagtaaccctgcagtgtattgtt aatggcataccaatcccttctatcacatggctgaaagataatcaacctgtaaatactgct agagaaaacattggactggaatcttcagggcacattttgcagattgccaaggccctaaaa tatgatgctggcagatacacctgtatagcaacaaatgcagctggtgaagcccaacaatcc atttatctgcatgtatatgagccacctagtctgaaggatgcaggaatgctaagaaatgag actgtaattgtgaacaatccaatacaactagtgtgcagagtgtctggaactcctttgcca gttgtcacatggtacaaaaataaccttcctctcatcaatattgctggcatcactttcttg aacagagggcaaattgctcaaatagatgcagcccagatctctgacactgggatttataaa tgtgcggtgacaaatgcagcaggagtagctgaattattctataatcttcaggtccatgtt ccaccctccatttcaggaaataatgaaatggtaactgttgtagttaatgatcaggtgagg ttggagtgtgaagctcgtggaattcctgctcctattctaacctggttgaaggatggcagt cccgtttctagtctttcaagtggactccagattcgttctggaggtcgcatcctggcactg acgagtgctcagatcagtgatactggaagatacacatgtgttgcagtaaatgcagcagga gaaaaacaaagggatattgatctcagagtttatgttccacctaatattatgggagaggaa cagaatgtctctgtggcaatgggagaacatttggaactccgctgccaaagcaatgcgata cctccacccatgcttcagtggctgaaggatggtcagctcctgcagaagaaactgggtctt accattactgaaggtggaagtatactgaagattgcacaagcacaggtgcaagacactgga cgctatacttgtgaagcaacaaacattgctgggaaaatggaaaaaaactacaatgtcaac atatgggtgccatcaagtatttacagttcagacacagtgactcagctgactgtaattgaa gggaacctcatcagcatgatgtgtgaatcccgtggaattccaccacctactctggcatgg aggaagaatggttctccactggtagttgaccctacggggagagtcagggtcttatctggt ggaagacaacttcaaatttctattgctgaaaaatcagattcagcctcttatacatgcata gcttcaaatgtagctggaataacaaagaaagaatataagttgctagtgtatgttcatcca actattctggacaatgggaatatacaatcggatgtcattgtaactcaagggaatgacatt tcatttgaatgccaagtggatggtattccacaaccgactgtcacctggatgaaagatggt caaccattggccaatgaaagaggagttgaaatactaaacgagggccacagtcttcgactt aaaagtgcacaggtgtcggatactggtcgctatgtatgtgttgctgtgaatgtggcagga ctgactgacaagaaatatgacttaagtgttcatgtccccccaagaattatgggtaatctg gtgcagccagaaaatgtaagtgctgtggagaaaagtcctgtcaacctgatttgtgaatct tcaggaattccccatccatcaataatgtggctgaagaatggacagccagtgtctttaagt aactctgtaagaatcctatcaggtggcaggatgttacgtctgatgcaggtgaaaatggaa gatgctggccattatatctgtgtagtaaataacattgcaggagaagacaggaaaaacttt gaactttcagttttagtacctccaagcattgtaggagaaaataaactagaagatgtaaaa gtaaaagaaggacatggcattacgttgacatgtgaagtcacaggaaaccctattccagag atcacttggttaaaagatggacaaacgtttctacaggatgatggctatcagttgatgtct agtggacgctttcttcaaattacaaacgctctagtcgctgacacagggagatatacctgt gttgcctccaatacagctggagacaaaagaaaaagcttcagtgttaatgtacttgtgtct ccatccattgtgggtgcagataataatgggggtgcagaagaagccacggttatcttaaat aacccaacctccttagtttgtgaggcttattcatatccaccagccacaatcacctggttg aaagatggagctcccatagattcaaatgagaacatcagggtgttgccaggtggtcgaact ttgcagattctgaatgcccaggaggacaatactggtagatatacttgtatagctacaaac gaagcaggggaaacattaaaacattatgaggtgaaagtttatattcctcctacgataagc agagacaatttatcaggactaggcttgtcccctaaagaagtgaaaatcagagtgaacaac agtcttaccctagaatgtgaagtccatgcaattcctgctgctggcatcagatggtacaag gatagacagctgattacatcagatgatcatttaacaatccaaggaggtggacgcatcctt caaattaaggcaactcagatatctgacactggccgatacagttgtgttgcttcaaaccta gctggtgaggatgagctggagtttgatgtcaatatacaagttcctcctagttttcgaaaa ccatttggattctgggaagatggagatgcgctaagtagaagacaaagaggaagagccaaa gatgtgattgtaaactatcctctgtctttatattgtgaaactaatgctgtgccccctcca gttcttacatggtataaagaggattttccactgagttccaatgataaagtacggatactt ccaggaggtcgtgtgttgcagatttctagagctcagagtgaagatgctggacgatatacc tgcgtggccactaatgaagctggagaagattctatccaatatgatgtccgcgtgcttttg ccaccatccattaacggtgccaacggtgatgtgactgaggagctgactgtacttctggac aagatggcaatgatggaatgtatagcagagggtattcctccttcaagcataatctgggag aaagatggacagctaatagctgaagattcccattacaaattccaactaggtggaaaaacc cttcagattcataatactcaaatagcaaatacaggcaggtatgtctgtcttgtggagaac atagcaggacgtgccaaaagatattttaatcttaacgtccatgttcctcccaatattatt ggaattaatcctgagaacctaactgttgtggtgaataacttcatctcactgacatgtgag gtcactggcttcccacctcctgatctcagttggctcaaggatggaaaacctctcagtttg aacacaaatattctcattgttcctggtggtcacacattgcagattcctaaggcacattta tctgatggtggtcaatatgtctgcatagcgagaaacagtgctggagaaagcatcaagagg actttccttactgtttatgttccaccaagtattaaaggcgagagcagcacacctcctgca atagtcaatgtgagagtgggaatgccagtgacattagagtgtgaatccaatgctgttcca cctcccatcatcacctggtacaagaatggccgtataatctcagtttcatccaatgtgggc tttatagcagatggacagacactccatatcaagatgaccgaggtatctgatacaggccag tatgtatgcaaagccataaatattgcaggacgtgatgacaaaacattccatcttaatgtt catgtactgcctaccattgaaggccctcagcaagagtggatcaatgaaaccatcagcaat cctattactcttacctgtgatgctactggaattcctccaccagctataacttggcttaag aatggaaaaccacttgaaaattctgccacccacgagttgcatattttatccggaggaaac aagctgcaaattaccaggcctcactattctgatactggaaattattcctgcattgcttca aatgtagaaggcaaagctcagaaattttatgttctttctgttgaaattcctccagatatt gttggttctgaaatgccaagtgaagtcagtggtatccttggagaaaacatccagatttcc tgtgaggctagtggaattcctacacctgtcattcagtggctaaaagatgggaaaccaatc agcaatggtgaatctcagcagataagtatggttccaaatgggagcttactaaacattttt ggagcccttacaagtgatggagggaaatatagttgtgttgctaccaatcctgcaggggaa gaggaccggatattcagtgtgaatatatatgtgccacccactatcagtaaaaataaagag gaacctgaggccctaactgtggtattagacacttcaataaacattgaatgtcaatctatg ggcactccacctgcccagataaattggctgaagaatggtcttcccctctctatatcttcc cacatcaggttactttcagctggacaagtactcagaattgttaaagcacaggtagctgat gttggcgtgtacacatgcatagcctccaacagagctggtgtcgacaataaacattatagt cttcaagtttatgtacccccaagcatagacaatggtggagaaacagaagaagtaactgta ctaaaagggaatcctgtatctttggtgtgtttggctaatggaataccaacaccaactata tcatggctaaaagatggtcagactttaagcagtaactttcatgtgacttttgaaaaccaa aaaatgggtcttcgtatattaaactcagaggttaatgatacaggtagatatacctgtata gcatccaatgaagctggggaagacaatcaacactttattctgaaagtgctagaacctcct catattaataaatcagataacccagaagaaatttctacagtgattaacaatcctcttgag cttctctgtatctctgatgggattccaatccccaaactaacatggatgaaggatggacgc ccactgcatcaagcagacactgttcatgtcctaagaggaggacaggtcttcagaatatcc agtgttcaggtagaagatactggaagatatacatgtttggcttctagccctgcaggagat gatgataaagaatatttagtgagagtacatgttcccccaaatatcgctggcacaagcaat tctcaaaatcttagtgtgctacagaaccagcaagttatactagagtgcaaatcagatgca gttcctcctcctgtccttacatggctcaaagatggagaaattttggaggctactcgccga gttcgcattttatccagtggaaggtatttgcaaatcaacaatgcagacttaaacgatgca gcaaattatacctgtgtcgcaagtaatgttgcaggccgaaccacaagaacgtttgtattg gatgtaaatgttcctccttcaatcaaaaatggttctcagactgtgattgtgaatattaat atgtctgctgtcttggagtgtgctgtggaaggtgttccagtcccaagaatttcatggaga aaagatggagcccttttagctggacacaatgtcagacattcactattaggaaatggatcc cttcacatacattcagcccaggttactgacactgggagatatctttgcatggcaaccaat gtggctggcactgagcgtaagaggattgatcttcaggtccatatttctccatatattgcc ccaggacctgtcaatgtcacagtatctgtaaatatacaaaccacactaccctgtgaaact acagggattcctaagccagccatagcctggaagaagaatgggcatgttctcaatttggat cagaactcattcaggcttttgtcgtcaggttcgctagtaattttttctccttctgtagaa gacactgcactctatgagtgtatagtaaccaatgaagcaggcaaagatcaaaggactatt agtctcatggtagaagtgccaccatccatagcagatgaagttacagatctattagtaacc aagtcatcacccataatcattccctgcacagcatcaggtgttccagtgccttcaatcctt tggaccaagaatggaataaagcttccttctcgaggaaatggcttcagaattctgtcttca ggtgctattgatataagcactgctcaactggaccattcaggaaaatatacttgcactgca tggaatgctgctggctctgcatatagacatatcacccttcttgttcagggtgaggtggga actaaaccaccaacaatacgaatgcaacccggagcattagctgttattctgaacaaccca gttctcctgccctgcaaagcatcaggcacacctcatcctgtgatatcatggcagaaggaa ggggtcagtgttattacaacagggaataggtatacagtacttcccaatggcagccttcag attgctaaagttgctgttgaagatgctggaacttacatgtgtgttgctcagaatccatca ggcactgctcttgggaagatcaaattaaaaattcaagttcctccagttatcaaatcacat cccagagaatatgtgattattatggataaacctgtcaccctgttgtgtgaagcagaaggc tatccgactcctttgattgcctggcaaaaaaatgaacagataatcacagagtccatgagg cgaagggttctcagcacggggggtttgcagattgcctttgttcagcctatggatactgga cattatacttgcaacgctactaacgcggctggatccagcagctccagtatggaactcact gtccttgtcccaccaaagatccatgcagtggaggaccactatacagttgttgaaaattca caagcagttctgtcttgtgttgctgatggaatgccagcaccatcagtgacctggaggaaa ggtgacacaagccttgtagctaagcgcagttctgaatcacatggagacttcattatagaa aaagctaagcctgaagattctgggagctacacctgtattgctaacaatgtggctggtgaa gacacccacactatcagtttaacagtttatgtcctcccagcttttactgaactccctgga gatgtagctttaaataaaggagaacaattgcaattaaattgtaaagcaacaggagttcct gtacccaacattaaatggatatttaacaataatattatcccagcacaatatgatggagta aacggactgagtaaacttgttattgagagagtgtctaagaaagattcaggaacctatgtg tgtatggcagaaaacctagttggttctatcaaggctcttggatctgtctatgttaaagaa cctccggtattcatgggacatgatcattccagtcggattgaacccttgggtggcaatgct attctcaactgtgaagtcacaggagaccctcctccaactattcagtggagcagaaaagga gttggtactctgatcagcaatcgaatcagacaacttagcaacggatcccttgtcatctat ggcacagttaatgaagatgctgcagaatatatatgtatagctacaaatgatgctggtgtt gttgaacaccatgtcactcttacattacatagtacacctgttattaaaactgaaccagca gagatcactgttgatgctggaaccacagcagtgctgaactgccaagcagaaggagaacct catccgactattgagtggtctcgtcaaggctggcctcttctgaatcaagaccgaatgact gttttgtcaaatggctctctgcgtattgcagttgctcataaagaggatacttctgaatat gaatgtgtagctaggaacctcatgggttctgtcctggtcaaagtgcccttcattgtccag gtgcatggtgggttttctcaatggcttgactggcaactatgtagtgtaacatgtggccgg ggtgtccaaaaaaggattcgtctatgcaacaatccttttcctgctaatggtggacgaagc tgtatggagcccgattatgaactacgcagctgtcagagcaagttgtgtccagtggatgca agctggtcagaatgggggtcttgggaagaatgctctaaagcctgtgggcaaggcaacaaa accagaaccagaagttgcagcaacccttcagctcaacatggaggaagaccctgtgaaggc aatgcagtggagtcaactgtgtgcaacataaggccctgcccagtgaatggaaaatggact tcctggtctagctggagtgcctgtaccatgtcttgtggaggaggtgcccaacagagaaca agagattgctcagacccacctccaaagaatggtggactcagatgtgaagggaatgatctt caggttggcttttgcaacactgacctctgccccacacatggaaactggggcccgtggagc aactgggggacttgcagtcgaacatgtaacggtggtcatacgagaagatatcggatttgt gacaatcctcatccacttaacggaggaagagcctgtgtgggggctgatacacagacccag aggtgtcgtggcgagctatgtcctgtgaatggaaactggggtccatggcagccttggagt gcatgttcagcttcttgtggtgctggggaaaagatccgatcacgattgtgcaacaatcca cctgtctctaacaatggacgtctttgtcctggagatgaggcgcaaatatccaggtgtaac attcaggcttgtccaggtggaccctcacatgctagaggaagcgtcattggacatattaat gatgttgagtttggaatcgctttcctgaatgctaccataatagatggtccagatgaggat attacaagtgtagaagccaaaattacaaatatccctcggaatcttggtcctgtaatgaaa gtgctggtttctattctgagtcccatttattggataacagccaaggaaattggagaagct gtgaatggcttttcactcaccagtgcagttttcaagcgggaaacacaagtagaatttgct actggggagcttctacgaatgactcatgttgcccgtggtttggattcagatggttcttta ctcttggatgttgtcatcagtggccacatactacagctacagtcaacagatgatgttaat gtaaaagattatacagaagattacattcaaacaggccctggtcagctttatgcttactcc actcggctcttcagcatagatagcgtcagtataccatacacttggaaccatacaattacc tacaatcaaaatcgtgggaaaatgccttccctggttgaaacacttcaagcttcttctatt aaaacagaatatagcccacatgaagaagctctgacttttaaaattgatgcttccattaca aaaggagaccacagcaaccaatgccctcatgggtttagtttggattcttctggtccctac tgttcagatgaagatgagtgtataactcaaaaaccatgtccccatatatgccacaatgtt gtaggaacctattactgctcctgtcccaaaggccttaccatatcagcagatggaagagca tgtcaagatattgatgagtgtgccttagcgaggcattcatgcttggtgggtcaagactgt gagaacattattggctcatatcgctgtgtgattcagtgtggaattggttttagaagaaca ccagatggattgagttgccaagatgtaaatgaatgccaagagtctcacccttgtcatcaa cattgcttcaactccattggaagcttccactgtggatgtgatccaggatatcagctgaaa ggcagaaaatgcatggatgtgaatgaatgcagacaaaatgtatgcagacccgaccagtta tgcaagaatacacgaggtggctataaatgcattgatctgtgtccaagtggaatgaccaaa gcagaaaatggaacatgtatagatattgatgaatgcagagacggtactcaccaatgccga tacaaccagttatgtgaaaactcaaaaggaagttatcggtgtgtgtgcccaagaggctat cgataccagggggttggaagaccctgcatggacattaatgaatgtgaacaagtgcctaaa ccttgtgcgtatcagtgtgccaacatccccggcagcttcaagtgtatctgtcctcctgga caacatttattaggcgatggcaaatcttgcgctggattggagaggttcccaaattatggc acctattacaatagctataattatgctcagttctcccccatgagagacaactatcgacca caacaatatatcaggcactcctccaatctctacagctcctactcagagtataggaacagc agaattcccatctccaggactagaagaaatgttagagagccttgccctgaaggctatgag gcaagaaataacaaatgtgtagacattgatgaatgtgagaacagaggtgtgtgtcagcat gaatgcaggaataccttagggagttaccagtgtttttgcccatcgggttaccgaaccatg cccaatggcaaaacatgtcaagacatagatgaatgccttgaacagaacatctattgtgga ccgaaccgcatgtgttttaacatgaaaggaagctatcagtgtgtagaaactccttgcccg ccacactatgaacgagatcttctttctggatcgtgcctcaagaagtgccgacccaatgac ttggaatgtgccttgagcccttatgctttggaatacaaacttgtatctctcccatttggg attgctgccaatcaggatctaatccgattagttgcctacactgaggatggagtgatgcac ccaaggaccagtttccttatggtgaacaaggaggacatgagcatccccttttcactcaga gatgagaacttgaagggggtggtgtataccacgaggcctctgctagagccagagacatat cggatgagagtcagagctctgtcttatagcagtgatggagccattgaatatcagatgact ttcatagtctatatagctgtgtctgcttatccttactag

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