Cotesia typhae: 141536735
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Entry
141536735 CDS
T11099
Symbol
Ds
Name
(RefSeq) dachsous cadherin-related 1
KO
K16507
protocadherin-16/23
Organism
ctyp Cotesia typhae
Pathway
ctyp04391
Hippo signaling pathway - fly
ctyp04392
Hippo signaling pathway - multiple species
Brite
KEGG Orthology (KO) [BR:
ctyp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04391 Hippo signaling pathway - fly
141536735 (Ds)
04392 Hippo signaling pathway - multiple species
141536735 (Ds)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04515 Cell adhesion molecules [BR:
ctyp04515
]
141536735 (Ds)
Cell adhesion molecules [BR:
ctyp04515
]
Cadherins
Cadherin related
141536735 (Ds)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cadherin
Cadherin_CELSR2_9th
Cadherin_2
RET_CLD1
CADH_Y-type_LIR
Motif
Other DBs
NCBI-GeneID:
141536735
NCBI-ProteinID:
XP_074113543
LinkDB
All DBs
Position
Unknown
AA seq
3296 aa
AA seq
DB search
MEEGTMIMVDGGGGFRGAVRLQSSRMIQLLLLSILITLLTPGGVNTEQVRHLEVSENAPP
GSRVGFIDLEGPPYLIVPVAGSPVINDLTVDPATGEIKTKLPLDRETNPSYSFVALPQRG
NIRVVIKVLDENDNAPTFPVDHVDIEFPENSPRDAKRALPPAKDPDLGQYSTQRYEIVSG
NFGDVFRLSQHRGRDGVLYLDLQNSGNLDREARSSYQLIIEALDGGSPPLRSRLKVNVIV
QDVNDNPPIFNQTRYSASVPENATVGTPVLQVNAIDLDIGSNGMIEYSINRRQSDREEMF
RIDNSSGMVFVNKALDFESKERHELVIVARDLGAQPLEASAFLSVYVTDVNDNQPTITVI
FLSDDATPKISESAQPGEFVARISVSDPDSRTEYSDAEVSLVGGENHFGLTTRDKIRYLV
VVERPLDREEQPIYDLAVEATDAGTPPLRAVRTFRLLVTDVNDNAPAFEQELYEAHLLEA
SEPGTAVIKVKATDVDEGVNSVIKYSLKNSTWFSIDKDTGLISTVTHVDCETDPAPNLVV
VATDSGRPSLTGTAIVRVTVHDLNDNEPIFEKPLYNTSVPEDLPVGHCFIKVQATDPDCG
VNSMVNYTLAAGQLASEQLFIRSDSGEICVRSPLDRELASYLELPVVATDRGGLSTTAIV
RIQVLDVNDNRPVFNPRDYNATIRSDAPPSDTIIKVIATDLDAGSFGQVTYRISGGNDAG
VFRIDRVTGELQVARPSLISRSPVHLLNVTASDTGGLNSLVDARVRVSVAMGQRLPICER
PRYAISARENVLQNSIIGDVKEAIVGDVTAAGATGKRPSRFFLATGENEFSIDPSSGVLR
TRIPFDRETRDKYVLSVGIRNNVGIGYCQVELTVEDVNDNPPGFPSTSVRISVPESHPLR
MALYVAHAWDPDTSPPAAVSYQLGQNSNDLFGIDSQTGELYLSRRLDYETQQRHNLMISA
VDGAGLSANITLSVEVQDVNDNPPVFERNEYHVEIPEGAKLDSQVLQVTALDLDTGNNAR
ISYRLQGSTLFRISPNTGWIYLRQPLDRETTDHYSLTVLATDNGSPAATASSMVQVTVLD
DNDNSPHFVKDFYTFELLENLPSGTVVGTIQAVDPDLGRNAQIRYTVVQHNSSFAIDPDT
GEIITREPLDRENKSLHELVLEARDQGTPSRAARVPLRVTVLDVNDNSPEIVDPQGDVVS
VREEQPPGTEVARVRALDSDLGENATITYSILKDRDSDGYNVFTIDPITGMIRTKSALDH
EERDVYRVSVKASDAGRPPRHSIRALRVEVLALADNRPTFTSSSLTFHVIEDASIGQSIG
SVSGAGPAGRVAYTLDSLAPVTNTPAFDVDRSSGQLVVAHSLDRENVSEYHLKIRALDTT
SIGNPQSIAVSVKIVIDDANDNAPRWPLDPIYIRVSEAAAIGTIIYNLTATDLDSGMNGD
LRYDLVSESPGSGSFAVDSLTGALSLVKPLDREEKTEYMLFLRATDRAALADRLSSTVTA
KIIVLDQNDNDPVFVAPEINKITVTTDLLPGTNIVRVIAVDNDTDNNGRVSYVIVSGNEE
SRFSLGYDSGVLTLMKPIVRDTVLQVAANDHGSPPRRAVMNLTVAIAVGQSRGPPRLLLA
NPVATVSENLAVGGFIINVVGSALGEQVNVTFDIPTGIADDKFTISSTGVVSLAAPLDRE
KNHRYSIPILAKSTKLLDLTTLEVNVQDENDNAPKFRPGSCYTLAVPENQDDAVIHTVAA
VDNDEGVNGEITYSIIGGNVGGKFKLDPVTGHLSAFNLDRETVARYNLAISAKDKGRPSL
ETRCNITVIVIDVNDNSPMFLREQYRPSKEFFPQTPQYQFANSYPHYIADKYVTSISEDT
APDSSILSVRATDPDQGINGKITYVITEETSWLFRVDNFTGVITTAGALDRERQSSYSFL
VIATDSGSYDAKSTSIPIEINLTDVNDNAPAFSETPFKASVPVTTQPGHTILQVEASDPD
VGANGEVSYAFSSDVETSKSKFRIHPTTGVLTAIASLTQDYGKTFHLQIVARDKGTPPRS
TQGLIELRVGDPDDVVPMLKFQNESYQVDVQENFAAGTEILQVTAVRTDGRRQHVAYSIA
SGNYFDTFVIDRYTGMLKINDPAKLDAELWIDSTESQSSRVLTLAAKTTGSEPLEAYAKL
VVKISDINDNAPIFTQTQYSATVLEGNAKGTFVVKLSASDADQDINGKILYHIVDGNPDN
AFTISPPYSGIVRTNIVLDREIREKYRLTIIATDQGNPQLTGTAALSVRVIDINDNQPTF
PGHKVIPVPEGSAVGTVLTTITANDVDSSPALTYRFGNVNHPSPFSIDRYGGKVTLTEPL
DAEDCDEYTVQVIASDGIHEAITDLTVRVLDVNDNHPKFQQAAYIATLSEGRGEVRELLA
VNATDEDLLEANNVVHYHLLSPVKGFSINSKTGVITANRTALSRPVPKEIELIVIAQDSG
KPALSSTCSVIIRLSGLRNSSSNREFKISVSENATRGTSLLKLADLGLLDGSIVSQEGTD
TFEISRGRLIISKNLDRESKDRYIVYLGTKTANSSNLATEDVVMVTIHVEDLNDNYPHFT
EELQEVTIKEDAQIGTVLTTIRASDNDLSGTLAATITYNITSGNDRHLFQIDPSSGLITV
NATLDCDLSPETHHLVILACDSDAVPLCSLARVRIHISDVNDNSPKFPVHEYLEFVGENE
PTGTRVFSARASDLDRGVFGTVNYSIVSAAASGFTDIDDSWKLFNVNPQTGAVTTGAIFD
YEQRNRYAFTLRATDTGGRTAAVKVRVEIDSRDEFYPQFTERMYRFDLRNGLQTVPGTVV
GHVTATDRDKGPDGRVVYQLTSQHPYFKLNRTTGALIVKKKLHYDSEESSRLVVSASSGR
QRSLSNMTVVEIRIIDDESNSLFSTNYPTNLGANMAVATSNGLADWALGLLIALVLLIAG
FGGFFLFVHLKNRKHKKPSAKPGLNGDGGATASNSYVDPTAFDTIPIRGVAGVASSVPNN
PGSCQFAPPKYDEIPPYGTSGQSVGQQATSEISGSDQSGSSGRGSAEDDGEDEEIRMINE
GQAADSASDLSVHNTQEYLARLGIVDAPSANSHSHARRPPEALPLDSDHLFEDEAVTEAE
IATLIYGKIGETRRPTSELEVPGGPSMNGSLSSIVHSEEELTGSYNWDYLLDWGPQYQPL
AHVFSEIARLKDDASVQSGSGNRHKVQQHKAPPPPLLTSVAPRSIAAPALARAMLPRSPI
SHDTSTFPSAALSPSFSPSLSPLATRSPSISPLVPPTPQRAQNPRNLPVVDSELRI
NT seq
9891 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggggacgatgataatggtagacggtggaggtggatttcgaggtgcagtcagg
ttacaatcatcacgaatgatccagctactgcttctcagcatcctgatcacgttattaacc
ccaggcggtgtaaataccgagcaagtacgacaccttgaagtatctgagaatgccccacca
ggtagtagagttggtttcatcgaccttgaaggcccgccgtatctcattgttccggtagca
ggttccccggttatcaatgatttgaccgttgatccagcaaccggggaaataaagaccaag
ctaccgctggaccgggaaactaatccgtcgtacagctttgtagcgttgcctcagcgagga
aacatccgcgttgtgattaaagttctcgatgaaaatgacaacgcaccgacctttcccgta
gatcatgtagacattgagtttcccgaaaactcgccgcgggacgcaaagcgggccctgccc
cccgctaaggacccagatttagggcagtactcgactcagaggtacgaaatcgtcagcggg
aactttggagatgtcttcaggctgtcccaacaccgaggaagggacggagttttgtacttg
gacctgcaaaattccggaaatttggaccgtgaagccagatcttcctaccaattgattatc
gaagcgttggatggaggctcgccgccgctgaggtccaggttgaaggtcaacgttattgtc
caggatgtcaatgacaacccgccgatcttcaaccagaccaggtactctgccagtgttcct
gaaaatgcgaccgtaggaactcctgttttgcaagttaacgccattgatttggacattgga
agcaatgggatgatcgagtactcgattaatcgcaggcagagcgaccgggaggagatgttc
aggattgacaactcttctgggatggtcttcgttaacaaggctctggactttgagtcgaaa
gaacggcatgagttggtgatagtggcccgagatttgggcgctcagccgctagaagcaagc
gcctttttgtcggtttacgtgactgatgttaatgacaatcagccaacgataacggtgata
ttcctctcggacgacgcgacacccaaaataagtgaaagtgcccaaccaggagaatttgtg
gctcggatttcggtaagtgatccagattcgaggactgagtattccgatgccgaagtgtct
ctggtcggcggagagaaccactttggtttaacgacacgtgacaaaattagatacctggtg
gtggtcgaacgcccgctggaccgcgaagaacagccgatatatgacttggccgtggaggct
actgatgctggaacgcctccgcttagagctgtcaggactttcaggctcctggtgacggat
gttaatgacaacgcgcctgcttttgagcaggaactctatgaagcccatttgttggaagct
tccgaacccgggaccgctgttatcaaagttaaggctacggatgtcgatgaaggtgttaat
tcggttatcaagtattcgttgaagaacagcacctggttctctattgataaggacactggg
ctgattagtacagtgacacatgtggattgtgaaaccgatccggctcctaatctcgttgtt
gttgctaccgactccggtagaccttctttgaccgggactgctattgtcagggttactgtt
catgatcttaatgacaatgagcccatttttgaaaaaccgctttacaataccagtgtacct
gaggatttgcctgttggacactgctttattaaggtacaggcgacggaccccgactgcggc
gtgaactccatggtgaactacaccctggcagcaggacaactcgccagcgagcagcttttc
atacgaagcgattctggcgagatctgcgtgagatcgccgttggatcgtgagcttgcttcg
tacttagaactcccagttgttgctacagatcgaggaggccttagtaccactgcaatagtc
aggatccaggtgctggacgtcaatgacaaccgaccagtgtttaatcctcgagactacaac
gcaaccatcagatcagatgcgcctccaagcgataccataataaaagtgatcgcaaccgat
ttggatgccggatccttcggacaggtgacttaccgaatttccgggggcaacgacgctgga
gtcttcaggatcgaccgtgtgacaggtgaactccaggtcgcccggccaagtctcataagc
agatctccagtacatttgctgaacgtgacggcgagcgataccggggggctgaacagcctg
gtggatgcccgtgtcagagtgagcgtggcgatgggtcaacggttgccgatctgcgagcgc
cccagatatgccatcagcgcgagggaaaacgtgctgcagaatagcattatcggggatgtt
aaagaagccattgttggagatgttacggctgctggagctaccggtaaacgaccgagcaga
ttttttctcgctaccggtgaaaatgaattctctattgatccttcctccggagtactcaga
actcggatacctttcgatcgtgagacacgtgataaatatgtccttagtgtggggatcagg
aataatgttgggattggatattgtcaagtggaactgacagtggaggacgtaaatgacaac
ccaccaggtttcccaagcaccagcgtccgtatatcagttcccgagtcacacccactgcgt
atggcattgtacgtagcccacgcctgggaccccgatacgagtcctccagcagcagtttct
taccagcttggacagaacagcaacgatctctttggaatcgacagccagaccggggaactt
tacctgtcccgtcggctggactacgagacccagcagcggcacaatttgatgatcagcgcc
gtagacggagcgggtctctccgccaacataactctcagcgtagaggtccaggacgtgaat
gacaaccccccggtgttcgagaggaatgagtatcacgtggagattcccgaaggcgccaaa
ctcgattcccaggttctccaagtgacggcactggacttggacactggtaataatgcgagg
ataagttaccgtctccaaggatctactctgttccgcataagtcccaacacaggatggatt
tacctccgtcagcccttggatcgggagacaaccgatcactactcgctgacggtcctggcc
acagacaacgggagtcctgctgctactgccagctccatggtccaggtcaccgtgctcgat
gacaatgacaacagtccgcactttgtcaaggacttctacaccttcgaactcctggagaac
cttccttcggggacagtcgttggaactatccaagcagtggaccctgatttgggcagaaac
gcccaaattaggtacactgttgtccagcataacagcagcttcgctatcgatccagatact
ggggaaataataactcgtgaacccttggaccgtgagaacaagagcctccacgagctcgtg
ttagaggccagagaccaaggaacgccgtcccgggcagccagggtgccgctcagagtcact
gttctagatgtcaatgataattcgccggaaattgtcgatcctcagggggatgtcgtcagt
gtgagggaagaacagccacctgggactgaggtcgcacgtgtcagggctctagattctgat
ttgggagaaaatgctactattacttacagtattctaaaagaccgcgactctgacggctac
aacgtgttcacaatcgacccaataaccgggatgatccgcacaaaatcagcgctggaccac
gaagagcgtgacgtctaccgcgtatctgtaaaagcaagcgacgcaggtcgtccaccacgt
cacagcatccgggctctgcgagtagaagtgctggctttagcggacaaccggccgacgttc
accagcagcagcttgacgttccacgtgatagaggacgcgagcatcgggcagtccatcggg
tcagtctccggagcgggtccagctggccgagtggcgtacaccctggactccctggctcca
gtgacgaacactccagccttcgacgtggaccggagctccgggcagctggtggtggcccac
tccttggatcgcgagaacgtcagcgagtaccacctcaagatccgcgccctggacaccact
tcgataggaaatccccagagcattgcggtctccgtcaagatagtgattgacgatgccaat
gacaacgctcctagatggccgctcgacccgatctacatccgggtctccgaagcggccgct
atcggcactattatttataatctgaccgccacagacctggacagcggaatgaatggcgat
cttcggtatgatctcgtcagcgagtcccccggcagcggaagcttcgccgttgattcactc
accggcgctctcagcctcgtcaagcctctggatcgcgaggaaaaaactgagtacatgtta
tttttacgcgctaccgatcgcgccgctctcgctgatcgtctttcctccacagtcaccgcc
aaaattattgtattggaccagaatgataatgatccggtgttcgtcgcacctgagatcaat
aaaattactgttaccactgatttattaccaggaacaaacatcgtgagagtaatagcagta
gacaacgacacagacaacaatggccgagtatcgtacgtaatagtttcaggaaacgaagag
tcaagattttccctcggctacgattcgggagttctaacactgatgaagccaatagtccgg
gacacggttctgcaagtggcagcaaacgaccacgggtcgccacctagacgcgcggtgatg
aacctgacagtagcgatcgccgtgggacaaagcagaggtcctccgcgacttcttttggcc
aacccagtggcgaccgtctcggaaaatctggccgtcggcgggtttattatcaacgtcgtt
ggatcagctctcggcgaacaagttaatgttactttcgatattccaacgggcatcgctgac
gacaaattcacaatatcttccacgggagtcgtctcattggcagctccgctggatcgcgag
aagaaccatcggtactctatcccgatccttgctaagtctacaaagctcctggatctcact
actctggaagtcaatgttcaggacgagaatgataatgctccgaaatttcggcctggctct
tgttacactctcgccgttcctgaaaatcaagatgatgctgttattcacaccgttgctgct
gttgataatgatgaaggtgtcaatggagaaattacttacagtattattggcggaaacgta
ggaggaaaattcaagctagatccagtaaccggtcacttatcagcattcaatctcgaccgg
gaaacagtagcgcggtacaacctcgcgatatccgcgaaagacaaaggacgacctagcctg
gaaacccgttgcaacatcaccgtaatcgtaatcgacgtgaatgacaactctcccatgttc
ctgagggagcaataccggccctccaaggagttcttccctcagactcctcagtaccagttc
gcaaactcgtaccctcactacatagccgacaaatacgtaacctcgatatcggaagacacg
gctccggattcctcgattcttagtgttcgagccaccgatcctgatcaggggatcaatgga
aagataacctacgtgatcactgaagagacttcttggctcttccgagttgacaattttact
ggagtaatcacaactgctggagcgttggatcgtgagcggcagagtagctacagcttcctg
gtgatagcgaccgatagcggtagctatgacgcgaaaagtacatcaatacccatcgagata
aatttaacagacgttaatgacaatgcacctgcattcagcgagacgccgttcaaagcgagc
gtgcccgtaacgacccagccggggcacacaatcctgcaagtggaagcctcagaccccgac
gtcggagcgaatggcgaggtctcctacgctttttcgagcgacgtcgagacctccaagtcc
aagttccgcattcacccgaccaccggggtcctcaccgcgatcgcttccttgacccaggac
tacggcaagaccttccacctccaaatagtcgccagagacaaaggaacgccgcctagaagc
actcaaggcttaatcgagctcagagttggagatcccgacgacgttgttcccatgctgaag
ttccagaacgagtcctaccaggtcgacgttcaggaaaactttgctgctgggacggaaatt
ctccaagtcactgcggtgcgcactgatggccggcggcagcatgttgcctactcgatcgct
tctggaaattattttgatacttttgtcattgatcgctacaccggcatgctcaaaattaac
gacccggcaaagctagatgctgaattgtggatcgattctacggaaagtcagtctagtaga
gtccttactttagccgctaagactactggatcagagcctttggaggcttatgctaaatta
gtcgtcaagatctctgatatcaatgataacgcgccaatttttactcagactcagtattcg
gctactgttctcgagggaaatgctaaaggaacttttgttgtcaagctatcagcaagcgac
gcggaccaagacataaacgggaaaatcctgtatcacatcgtagacggcaacccggacaac
gcgttcaccataagtccgccatacagcggaatagtgcgaacgaacatagtcctggaccgg
gagatccgggagaagtaccgcctcacaataatagcaacggaccaaggcaacccccaattg
acgggaacagcggctttgagtgtgcgagtgatcgacataaatgacaaccagcctaccttt
cctgggcacaaagtaattccagttcctgaaggttctgcggttggcaccgtcctgacgaca
ataaccgcaaacgacgtggacagctccccggcgttaacctatcgtttcgggaacgtaaat
cacccgagtccgttcagcatcgatcgttacggcggcaaggtcacgctaaccgagcctttg
gacgctgaagactgcgatgagtacacggtccaggtgatcgccagtgacggaatccacgag
gcaatcactgatctcactgtcagggtcctcgacgtaaatgacaatcatccgaaattccag
caggccgcttacatcgccaccttatcagaaggccgaggtgaagtacgtgaattactggca
gtaaacgcgacagacgaggatctcctggaagccaacaacgtggtacactaccaccttcta
agtcccgtaaaaggctttagtataaactccaagaccggagtgataactgccaacagaacc
gcactgtcgcgccctgtgcccaaggagattgagttgattgtcattgcacaggactccggg
aagccggcgctctcctcaacttgctcggtgatcatcaggttgagcggactcaggaactct
tcttcgaaccgggagttcaagatcagtgtcagcgaaaacgccactcgggggactagtctt
cttaagttggctgatctggggcttctagacggcagcattgtatctcaagaaggcactgat
acttttgaaatttctcgcggacgtttgattattagcaagaatttggatcgcgaatctaaa
gacagatacatcgtttatctcggaacgaaaaccgcgaactcatcaaaccttgcaacggag
gacgtagtaatggtaacaatccacgtagaggacttgaacgacaactaccctcacttcacc
gaagaactgcaagaagtcaccataaaagaagacgcccagatcggaacagtcctaacgaca
atccgtgcgagcgacaacgacctctcaggaaccttagcagcgacgataacctacaacata
acctccggaaacgaccgtcatttattccagatagatccatcatcaggcttgataacagtg
aacgcaactttagactgcgacttgtccccagaaacgcaccacctggtgatcctagcgtgc
gacagcgacgctgttccactgtgttccctcgccagggtgcgcatccacatctctgacgtc
aacgacaactccccgaagttcccagtgcacgagtatctagaattcgtgggtgaaaatgag
cccacaggaacccgagtgttctcagcacgagcttcggacctggatcggggagtttttgga
acagttaattactcaatagtatctgcagcagcctccggcttcacggacatcgacgactcc
tggaaattatttaacgtgaacccgcagaccggagcagtgacaactggcgccatctttgac
tacgagcagcgtaaccgctacgcgtttaccttgagagcaaccgacacaggtggcaggact
gcagcggtgaaggttagagtagaaatagactccagagacgagttctatccgcaattcacg
gaaagaatgtaccggttcgacctccggaacggcttgcagacggttcctggaaccgtagtc
ggccacgtgacggctactgaccgcgacaaaggccccgacggccgcgtggtttaccaactg
acctcccagcacccgtacttcaagctaaaccgcaccacgggggcgctgatagtcaaaaag
aagctgcactacgactctgaagagtcttctaggctcgtagtgagcgccagttccggcaga
cagcgctcgctgtccaacatgacggtagtagagatccggattatcgacgacgagtcaaac
agtctcttctccaccaactacccgacgaacttgggcgccaatatggccgtagcgacgtct
aacggccttgcggactgggctttgggactcttgatagcgctagtgctgctaatcgccggg
ttcggggggttcttcttgttcgtccatcttaagaatcgaaagcacaagaagcccagtgct
aaacctggcttgaacggcgatggcggcgccactgcgtctaacagttacgtagatcccacg
gcttttgatacaattcccatccgcggggtcgctggcgtcgcttctagtgttccgaacaat
ccagggtcttgtcagttcgctccgccgaagtatgacgagatcccgccgtacggaacctcg
gggcagtctgttgggcagcaagcgacctccgagatctccgggagtgatcagtctgggtcc
tctggccgcggatctgctgaagacgacggggaagatgaagaaatcaggatgatcaatgaa
ggacaggctgctgattctgccagcgatctttccgttcataacactcaggagtacttggcc
aggctgggaatcgtcgacgctccctcggcgaactctcactcgcacgctagaagacctcca
gaggcgcttccgctggacagcgaccacttgttcgaagacgaagcggtcactgaagcggag
atcgcgacgcttatctacggaaagatcggagaaaccaggagacccacttcggaactggag
gttcctgggggtccttccatgaacggttctctgagttccattgttcacagtgaggaggaa
ctcactgggtcctacaactgggactatcttctagactggggcccgcagtaccagccactc
gctcacgtcttcagtgagatcgccaggctcaaagatgacgccagtgttcaaagcggttcc
gggaaccgacacaaggttcagcagcacaaggcccctccgccgcctttgctcacttccgta
gcgcccaggtccatcgctgcccctgctttggctagagctatgcttcccaggagccctatt
agccatgacacttccactttcccctctgcggcgctcagtcccagtttttcaccctctctt
tcgcccctcgccactcgcagccccagtattagccctcttgttcctcccactcctcagagg
gcacagaatcccaggaacttacccgttgttgatagcgaactgaggatctaa
DBGET
integrated database retrieval system