Corynebacterium ulcerans 809: CULC809_00317
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Entry
CULC809_00317 CDS
T01880
Symbol
hemD
Name
(GenBank) uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cuc
Corynebacterium ulcerans 809
Pathway
cuc00860
Porphyrin metabolism
cuc01100
Metabolic pathways
cuc01110
Biosynthesis of secondary metabolites
cuc01120
Microbial metabolism in diverse environments
cuc01240
Biosynthesis of cofactors
Module
cuc_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cuc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CULC809_00317 (hemD)
Enzymes [BR:
cuc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CULC809_00317 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CULC809_00317 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AEG80857
UniProt:
A0AAN0PP10
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Position
352558..354246
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AA seq
562 aa
AA seq
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MSLTPQPNPVTPLPEGKVIFVGAGPGNPDLLTVRAREVLSHTAFAVVDAEVLPGVRSVVA
RELDVPADKIQAAEEEYERLCAEAKEAGARRKPQRPDAPTAAEITEVDDEVPVAEIVDKL
KELLTTGEDVIRLVQGNPLSCDRTLEEISAVTQAGLEFHVVPGMSLPATVPAFAGIALGS
SYTETDVTGEDVDWEQLASAPQPLVLQATKDDLPTIAAELKARGLAASTPVTVTAHGTTR
LQRSFDVSLGALSKLDGDLAGTLVVTLGKAVDERTKYSWWENRSLFGWRVLVPRAKEQAG
PMSTLLASQGAIPQEVPTISVEPPRNPAQMEKAIKGIVEGRYQWVIFTSVNAVKAVREKI
GSFGLDARAFAGVRIGAVGTKTAKAIRELGITPELLPPRNQQNAAGLVSVFPEYVEDLDP
VGRVLLPRADIATDVLVEGLEGLGWEVDDVVAYRTVRAAPPSAEVRDMIKSGGFDAVCFT
SASTVKNLVGIAGKPHQRTIIACIGPMAEAAAKELGLRVDVVPEVADVPHLVNSLAAHVA
QLRAAGQLPPPRKKRRARKNRE
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgagtctcactccgcagcccaatccggttacccctttgccggagggaaaagtgatcttc
gtaggagcaggaccaggaaaccctgatctgctcaccgttcgcgcccgcgaagttctcagc
cataccgcttttgccgtagtagacgcagaagtactcccgggggttcgctctgtagtcgca
cgtgaactggatgttccggccgataagattcaggcggctgaggaagaatacgagcgcctc
tgcgcagaggcgaaagaggccggcgctcgccgtaagccgcagcgtccagatgccccgacc
gcagctgagatcacggaggtggacgatgaggttccggtggcggagattgtcgacaagctt
aaggagcttttgactacgggcgaggacgttatccgccttgtacaggggaaccctttgtct
tgcgaccgtactttggaagaaatatctgcggtcactcaagctggactggaattccatgtt
gttccaggtatgtccttgccagcgaccgttcccgcttttgccggcatcgcactggggtct
tcttatacggaaactgatgtgaccggcgaagacgtggattgggaacagctggcgtcagca
cctcaaccgctggtcttgcaggcaaccaaagatgacctgcccacgatagcggcagagctc
aaggcccgtggattggcggcatcgacaccggtgacggtgactgctcacggcacgacacgt
ttgcagcgaagctttgacgtcagcttgggtgctctgagcaagttggatggggatctcgct
ggcaccctcgtggtcaccttaggcaaagccgtggacgagcgcaccaaatattcctggtgg
gagaatcgctcgctctttggctggcgagtcctggtgcctcgcgctaaagaacaagccggc
cccatgagcacattgttggcttcgcagggggcaattccgcaagaagtccccacaatttcc
gtagaaccgccgcgcaaccccgcgcaaatggagaaagccattaagggaatcgtcgaggga
cgctaccagtgggtgatctttaccagcgttaacgcggtgaaagctgtgcgagaaaagatc
ggttctttcggcctcgatgcccgcgcctttgccggcgtacgcatcggtgcggtgggaaca
aaaaccgctaaggctatccgcgagctggggattactcccgagctgttgccgcctaggaat
cagcaaaatgctgcaggcttagtgtcggtgttcccggaatatgtggaagaccttgaccca
gtgggaagagtcctcttgcctcgcgcagatattgcaacagacgtcctggtagaaggccta
gagggcttgggctgggaagtcgatgatgtggttgcgtatcgcacggtacgcgctgcgccg
ccgagcgcggaagtgcgcgacatgattaaaagtggcggttttgatgcagtgtgctttacc
tctgcgtcgacggtgaaaaacctggtgggcatcgccgggaaaccgcatcagcgcacgatc
atcgcatgcatcggtcctatggcagaagctgcggcaaaagaattaggactgcgagtggat
gtggtccctgaggtggcggatgtcccacacctggtgaacagccttgccgctcacgtggca
caactccgtgcagctggtcagctaccaccgcctaggaagaaacgacgcgcccggaaaaat
cgcgagtaa
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