KEGG   Cuculus canorus (common cuckoo): 104055376
Entry
104055376         CDS       T08597                                 
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cuca  Cuculus canorus (common cuckoo)
Pathway
cuca00562  Inositol phosphate metabolism
cuca01100  Metabolic pathways
cuca04020  Calcium signaling pathway
cuca04070  Phosphatidylinositol signaling system
cuca04081  Hormone signaling
cuca04082  Neuroactive ligand signaling
cuca04261  Adrenergic signaling in cardiomyocytes
cuca04270  Vascular smooth muscle contraction
cuca04310  Wnt signaling pathway
cuca04371  Apelin signaling pathway
cuca04540  Gap junction
cuca04621  NOD-like receptor signaling pathway
cuca04912  GnRH signaling pathway
cuca04916  Melanogenesis
Module
cuca_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cuca00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    104055376 (PLCB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    104055376 (PLCB4)
   04371 Apelin signaling pathway
    104055376 (PLCB4)
   04020 Calcium signaling pathway
    104055376 (PLCB4)
   04070 Phosphatidylinositol signaling system
    104055376 (PLCB4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    104055376 (PLCB4)
   04081 Hormone signaling
    104055376 (PLCB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    104055376 (PLCB4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    104055376 (PLCB4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    104055376 (PLCB4)
   04916 Melanogenesis
    104055376 (PLCB4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104055376 (PLCB4)
   04270 Vascular smooth muscle contraction
    104055376 (PLCB4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cuca04131]
    104055376 (PLCB4)
Enzymes [BR:cuca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     104055376 (PLCB4)
Membrane trafficking [BR:cuca04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    104055376 (PLCB4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    104055376 (PLCB4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 104055376
NCBI-ProteinID: XP_053918710
LinkDB
Position
3:81420453..81625810
AA seq 1206 aa
MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESNCLFQVDEFGFFLSWKSEGKEGQVL
ECSLINSVRFGTVPKDPKILTALEAVGKSENELEGRIVCVCSGTDLVNISFTFMVAENTE
IAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGVISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQPLETHPLDPGKPLPSPNDLKRKILIKNKRLKPEVEKKQLDALKKM
MEAGETAAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVE
DSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNI
HHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA
VLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGF
GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQ
SSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAK
EHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCLELKKETEIKIQTLTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFS
HDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGL
KPQQAN
NT seq 3621 nt   +upstreamnt  +downstreamnt
atggcaaaaccttatgaatttaactggcagaagccagttccctcctttatgcaagatgga
gctgtgtttgatagatatgaagaggaatcttttgtctttgaaagcaactgtctcttccaa
gtggatgaatttggcttttttctgagctggaaaagtgaaggaaaggaaggacaggtatta
gaatgctccctgatcaacagtgttcgttttggaactgtaccaaaggatcccaaaatacta
actgcacttgaggctgttggaaaatcagaaaatgagttggaaggacggatagtctgtgtt
tgcagtggcacagatctggtgaacatcagcttcactttcatggtagcggaaaacacagaa
atagccaagcaatgggtagaagggcttggatccatcatacataactttagagctaacaat
gttagtccaatgacatgtctcaagaaacactggatgaagctggcctttctaacaaacaca
aatgggaaaattccagttcggagcattaccagaacctttgcatcaggcaaaacggaaaaa
gtgatctttcaggcacttaaggaattaggtcttcccagtggaaagaatgatgaaattgag
cctgcagcatttacttatgagaaattttatgagctcacccaaaagatatgtccccgaact
gacatagaggacctatttaagaagatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcggctcaatgaaattttattt
cccttttatgacacaaaaagagcaatgcagataattgagacatatgagccagatgaagac
ttgaagagtaaaggtgtcatatcaagtgacgggttttgcagatacttgatgtcagatgaa
aatgccccagttttcctagaccgtttggaattataccaagaaatggatcatcctttggct
cattatttcatcagttcctctcacaatacatatttaacaggcaggcagtttggtggcaag
tcttcagtggagatgtacagacaagtgcttttggctggatgcaggtgtgttgagctggac
tgctgggatggcaaaggtgaagaccaagagccaataataacccatggaaaagcaatgtgt
acagatatccttttcaaggatgtaattcaagctattaaggaaacagcatttgttacatca
gagtatcctgtcattctttcatttgaaaatcactgcagcaaatatcaacagtacaagatg
tcaaaatattgtgaagatctttttggagatctcctgttgaagcagcctctagagacacat
ccacttgatccaggtaaacccttaccttctcctaatgacctcaaaagaaagattctcata
aagaataaaaggctgaaacctgaagtagaaaaaaaacagcttgatgcgctgaaaaagatg
atggaggctggggaaaccgctgctcctgtaaatatcctagaggatgataacgaagaagaa
atagaaagtgctgaccaggaagaggaagctcatccagagtacaaatttggaagtgacctt
actgtagatgattacagtcaaaaagaagctgttgccatcagcgtcaaaaaggctgttgaa
gattctgagcaagaaaacaataaaaagggtttagtaactgttgaagatgaacaagcttgg
atggcatcttacaaatatgtaggtgccacaaccaatatacatccatatttatcaacaatg
gtcaactatgctcaacctgtaaaatttcaaggtttcgatgtagcagaagaacgtaatatt
catcataatatgtcctctttcaatgaatcagttggactagggtatttgaagacccatgcc
attgagtttgtgaattataataaacgacaaatgagtcggatatacccaaagggaggccgc
gtggattccagtaattacatgcctcagattttctggaacgctggctgccagatggtctca
ctaaactatcagaccccagatttagcaatgcagttgaatcaagggaaatttgaatataat
ggatcatgcgggtatctacttaaaccagatttcatgcgacgaccagatcggacgtttgac
cctttctctgaaactcctgtagatggtgtaattgctgcaacatgttctgtacaggtaata
tctggtcagttcctatcagacaaaaagattggtacgtatgtagaagtggatatgtatggt
ttacccacggacacgatacgtaaagaatttcgaacacgcatggtgatgaacaatggtctg
aaccctgtttacaatgaagaatcatttgtatttcgaaaggttatccttcctgatcttgct
gtcctaagaatagcagtatatgatgacaataataagttgattggtcagaggatcctgcca
ctggatggtctgcaggcaggttacagacacatttcacttcggaatgagggcaacaaacca
ctctctcttccaacggttttctgcaacattgtgcttaaaacatatgtgcctgatggtttt
ggagatattgtggatgctttatcagatccaaagaaatttttgtctatcacagaaaaaaga
gcagaccaaatgagagctatgggtatcgaaactagtgatatagctgatgtaccaaatgac
acttcaaagaatgatagaaaaggaaaagccaataatgccaaagccaatgtaacacctcag
agtagctctgaacttcgaccaagcaccactgcaggctttggatctgggactgacgctaag
aaaggtatagatcttattcctcaagtgaagatagaagatttaaagcaaatgaaggcttat
ataaagcatttaaagaaacagcagaaagagctgaatgccttaaagaagaaacatgccaag
gagcacagcgctatgcagaagttgcactgcacacaaattgacaaaatagtggcacagtat
gataaagaaaaggtatcttacgagaaaatgttagagaaagcaatcaagaagaagggagga
agtaattgtcttgaattgaagaaagaaacggaaattaaaattcagacactaacatcagat
cacaaatctaaggtcaaagagattgtggcacagcacactaaagagtggtctgagatgatc
aatacgcacagtgccgaagagcaagaaatccgtgatttacacttgaaccaacagtgtgaa
ctactgaagaaactgctgattaatgctcatgaacaacaaacccagcagctaaaattttca
catgacagggagagcaaggaaatgcgtgccaaccaggctaaaatatctatggagaacagc
aaagccataagccaagacaaatctatcaaaaataaagctgaaagagagaggcgagtcaga
gaactgaacagcagcaacacaaaaaagttcctggaagaaagaaaaaggctggcaatgaag
caatcaaaggaaatggatcagttgaaaaaagttcaacttgagcatttagaagtcttggag
aagcagaatgagcagcttttgaaatcctgtcatgcagtgtctcaaacacaaggcaaagga
gatgcagcagatggtgaagctggaagcagagatggatcgcaggccagcaacagtggtcta
aagcctcaacaagcaaattga

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