KEGG   Cuculus canorus (common cuckoo): 104065161
Entry
104065161         CDS       T08597                                 
Symbol
MAP2K1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
cuca  Cuculus canorus (common cuckoo)
Pathway
cuca04010  MAPK signaling pathway
cuca04012  ErbB signaling pathway
cuca04068  FoxO signaling pathway
cuca04114  Oocyte meiosis
cuca04140  Autophagy - animal
cuca04148  Efferocytosis
cuca04150  mTOR signaling pathway
cuca04210  Apoptosis
cuca04218  Cellular senescence
cuca04270  Vascular smooth muscle contraction
cuca04370  VEGF signaling pathway
cuca04371  Apelin signaling pathway
cuca04510  Focal adhesion
cuca04517  IgSF CAM signaling
cuca04540  Gap junction
cuca04620  Toll-like receptor signaling pathway
cuca04810  Regulation of actin cytoskeleton
cuca04910  Insulin signaling pathway
cuca04912  GnRH signaling pathway
cuca04914  Progesterone-mediated oocyte maturation
cuca04916  Melanogenesis
cuca05132  Salmonella infection
cuca05164  Influenza A
Brite
KEGG Orthology (KO) [BR:cuca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104065161 (MAP2K1)
   04012 ErbB signaling pathway
    104065161 (MAP2K1)
   04370 VEGF signaling pathway
    104065161 (MAP2K1)
   04371 Apelin signaling pathway
    104065161 (MAP2K1)
   04068 FoxO signaling pathway
    104065161 (MAP2K1)
   04150 mTOR signaling pathway
    104065161 (MAP2K1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    104065161 (MAP2K1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    104065161 (MAP2K1)
   04148 Efferocytosis
    104065161 (MAP2K1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    104065161 (MAP2K1)
   04210 Apoptosis
    104065161 (MAP2K1)
   04218 Cellular senescence
    104065161 (MAP2K1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104065161 (MAP2K1)
   04540 Gap junction
    104065161 (MAP2K1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    104065161 (MAP2K1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    104065161 (MAP2K1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    104065161 (MAP2K1)
   04912 GnRH signaling pathway
    104065161 (MAP2K1)
   04914 Progesterone-mediated oocyte maturation
    104065161 (MAP2K1)
   04916 Melanogenesis
    104065161 (MAP2K1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    104065161 (MAP2K1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    104065161 (MAP2K1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104065161 (MAP2K1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cuca01001]
    104065161 (MAP2K1)
Enzymes [BR:cuca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     104065161 (MAP2K1)
Protein kinases [BR:cuca01001]
 Serine/threonine kinases: STE group
  STE7 family
   104065161 (MAP2K1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7
Other DBs
NCBI-GeneID: 104065161
NCBI-ProteinID: XP_053933251
LinkDB
Position
12:14419095..14456016
AA seq 395 aa
MPKKKPGPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKV
GELKDDDFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHE
CNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYL
REKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHY
SVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCPVEGDSPVTETSPRQRTPGRPVS
SYGPDSRPPMAIFELLDYIVNEPPPKLPNGVFGSEFQDFVNKCLIKNPAERADLKQLMIH
AFIKRSEAEEVDFAGWLCSTIGLNQPSTPTHAAGV
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgcccaagaagaagcccgggccgattcagctcaatcccgctccggatggctccgccgtc
aacgggacgagctctgcagagacaaatttggaagcacttcagaagaagctggaagaacta
gagctggatgaacagcaacggaagcgcctcgaagcttttcttactcagaaacaaaaagtt
ggagagctgaaggatgatgactttgagaagatcagtgaactgggagcaggaaatggaggt
gtggtcttcaaagtgtctcacaagccttctggtctcatcatggcaagaaagttaattcat
ctagagatcaagccggctattcgaaaccagatcattcgcgagctgcaagttctacatgag
tgcaactctccgtacatagtgggcttttatggagctttttacagtgatggagaaatcagc
atttgcatggaacatatggatggtggctccttggatcaagtactgaaaaaggctggaaga
attccggagcagatactgggcaaagttagcattgcggtaataaaaggactcacatatctg
agagaaaagcataaaataatgcacagagatgttaaaccatctaacattttggtaaactct
agaggtgaaatcaagctttgtgattttggtgtcagtggacaactgatagattctatggca
aactcgtttgttggcacacgctcctacatgtctccggaaagactacaaggaactcattat
tcagtgcaatcggatatatggagcatggggctgtcactggtagaaatggctattggcaga
taccccattcctcctcctgactctaaggagcttgaattaatgtttggctgcccagtggag
ggagactctccggtcaccgagacctcacccaggcaaagaacacctggccgaccagtgagc
tcttatggaccagacagcagacccccaatggccatctttgaacttcttgattacatcgtc
aatgagccacctccaaaactgcccaatggtgtttttggttctgagtttcaagactttgtt
aacaagtgtttaattaaaaatcctgctgagagagctgatttgaagcagctgatgattcac
gctttcattaagagatctgaagcggaggaggtggattttgcggggtggctttgttcaacc
ataggccttaaccaaccgagtacacccacgcatgctgctggagtctga

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