Cuculus canorus (common cuckoo): 104065325
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Entry
104065325 CDS
T08597
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
cuca
Cuculus canorus (common cuckoo)
Pathway
cuca00270
Cysteine and methionine metabolism
cuca00480
Glutathione metabolism
cuca01100
Metabolic pathways
cuca01240
Biosynthesis of cofactors
cuca04216
Ferroptosis
Module
cuca_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
cuca00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
104065325 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
104065325 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
104065325 (GCLC)
Enzymes [BR:
cuca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
104065325 (GCLC)
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
104065325
NCBI-ProteinID:
XP_009566077
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All DBs
Position
3:complement(8726554..8762605)
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AA seq
636 aa
AA seq
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MGLLSQGSPLGWEETRRHAEHVRRHGILQFLHIYRAVRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLVLCGEEVLQTLQDKGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPEYKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIESFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGSAQNGTGTDTEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEMNY
SLIWKCNQIAQGQAECPELLGVGFNKKQSGNKTGSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgggctgggaggagacgcggcggcacgccgag
cacgtgcgcaggcacggcatcctccagttcctccacatctaccgcgccgtgcgggaccgc
cacaaggacgtcctcaaatggggtgacgaggtggaatatatgttagtaaaatttgaccat
gagaataagaaagtgcgcttggtgctctgcggtgaagaagttcttcaaacgctgcaagac
aagggcgagaagataaaccccaaccacccaacactctggcgaccagaatatggaagctat
atgattgaagggacacctgggcagccctatgggggaaccatgtccgaattcaacactgtg
caagacaacatgaggaaaagacggcaagaggctgcttctgtgctcaaagaaaatgaggct
gtttgcaccgtgacgtcatttccaaggttagggtgtcctgggtttacgctgccagaatat
aagccaacgccagtagaaggaggggcttcaaaatccctcttttttccggatgaagccatt
aataaacatcctagattcagcacactgaccagaaacattcggcatcgaaggggagaaaag
gttgtgataaacgtaccaatatttaaagataagaacacaccatcaccatttatcgaatcg
tttcctaatgatgatggagaagcagcaaaggcggctaagccggactatatatacatggat
gctatgggttttggaatgggaaactgttgtcttcaggtaacgttccaggcttgcagcatt
tccgaagcgaggtatctctatgatcagctcgccacgatctgtcccattgtgatggcattg
agtgctgcgtctccattctacagaggctatgtgtctgacatcgactgtcgctggggagta
atctccgcatcagtagatgatcgaacacgggaagagagggggctagagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagatcca
ttgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aatattcagtctacaaactggcagacaatgaggtttaagccacctcccccaaattctgat
attggttggagagtggaattcagacctatggaggttcagttaacagactttgaaaactct
gcgtatgttgtgtttgtggtactactaaccagagtgattctgtcatacaagctggatttt
ctcattcctttgtccaaggtggatgaaaacatgaaagtggcccagaaaagagatgctgtc
cggcaaggaatgttttacttcagaaaagatatttgcaaaggtggaaacgctgttgtggat
ggatgcggctctgcacagaatgggacaggcactgacacggaagagtacaccctaatgagc
attgatacaattatcaatgggaaggaaggagtttttcctggtttgatcccaattttgaat
tcctatcttgaaaacatggaagtggatgtggacacaagatgcaccatcctaaactacctg
aagctaataaaaaagagagcatctggagaactaatgacagttgctcgatggatgagggaa
tttatcgcacagcacccagactacaagcaagacagcgtgataactgatgaaatgaattac
agccttatttggaaatgcaaccaaatcgcacaaggccaagcagagtgtcctgaactactg
ggggtaggatttaataagaaacaaagtggaaacaaaactggttctttgtaa
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