KEGG   Cuculus canorus (common cuckoo): 104067867
Entry
104067867         CDS       T08597                                 
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
cuca  Cuculus canorus (common cuckoo)
Pathway
cuca00562  Inositol phosphate metabolism
cuca01100  Metabolic pathways
cuca04020  Calcium signaling pathway
cuca04070  Phosphatidylinositol signaling system
Module
cuca_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cuca00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    104067867 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    104067867 (PLCE1)
   04070 Phosphatidylinositol signaling system
    104067867 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cuca04131]
    104067867 (PLCE1)
Enzymes [BR:cuca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     104067867 (PLCE1)
Membrane trafficking [BR:cuca04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    104067867 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    104067867 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like
Other DBs
NCBI-GeneID: 104067867
NCBI-ProteinID: XP_053927376
LinkDB
Position
7:17281723..17425530
AA seq 2305 aa
MTSEDITASVLVSVVQSKVIPAQSAGNENTENASDTSVIKRHTASPGRQPTRAFSYLHRL
EEESLQDSVPEIFSLAKDQMTNDSTHENFWERESSIPDSVEFLNINCNVVQKNCERNIPC
SQLYKSCDPSTGGEACLETGNPVSLERAMLAEIQLKMNGPSLRSQTAVNKNDSNDIDKVA
FFHFHCASEKNISKALCSLHNGFILDDCLQPVSVGDGNTTGSLACACRLMELTNNCENEN
GQQLYEGALRDKYLCLEREPQKDKVACLGPDFCGNNFTGRMPSKPFLSHFEDCNDNCEEM
EEDLFRNKKERSTLLIRRFCKNDKEVKKSVYTGTRAIVKTLPSGHIGTIAWNYVEQRRNN
SGLKISRITTEQLTVIHSLIKWEFNSFLEKSLWYEIFSTVREDEGEDIFEYFPHLLRKLP
TFNTDCTCKDDGFSVKQCVTGPYCRYRATSQRTALSKYITGALLEATTSLGARSGLLNIF
GGSSGRTMLKERQACMSMAGSSIFPSNVAGISKELIELQHLIQFPEEVASILTEQEQELY
QKVLPIDYLCFLTRDLGNAECQSKLPSIKASISATILSSPNGEHNAVEDLVTRFNEVSSW
VTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQTD
IETMRSLKDAMAQHESSSEYRKVVNRALNIPGCKVVPFCGVFLKELCEVLDGASSLIRLC
PRYNSQDETLEFVSDYSGQDNFLQRVGQDGLSNPEKESTANNIFQTIRSCNRSLESEEGE
DNFSEGSNSRKNSLKDKTRYHAAHVKKASDSNQVLFIIGDLSDSESDIFEQLKEWDTNST
EEQQKAFCHGIELIPWYVLSIRADVHQFMQQGATVIHYDQETHLSARCFLQLQPDNSTLT
WTKPTTVCPANAKAKLSVLGSSAELGKYQLLGNTGLVEGFLDLFSAKAVYMGHSGIDMHT
VCVQNKLCNMSLEENGVTLLYGLHTTDNKLLHFVAPKYTARMLYDGLLELTKAVRKMRRF
PDQRLQWLRKQYVSLYQEDGRFEGPTLAQAIELFGGRRWSARNTSTGTLTKNMEKASVQR
NNTLGISTAKKKKKVLMRGESGEATDDEMATRKAKSCKEYRNRSGSDPQDIDEQEEPDQN
IIINACPSNNLPSRRAHSLTASGSPNLGATSSSPARPVSSPVMSSNKSQSSTWSSSSWHG
RVKGGMKGFQNFMVSDSNMTFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGLEPAPL
YTNLKIDENSSGFQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGV
ESTSLGIFGVGIQQLNDFLVNCQGEHCTYDEILSIIQKFEPSVNMCQQGLLSFEGFARFL
MDKDNFASKNDESQENAEDLNFPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCR
SVELDCWDGDDGMPIIYHGHTLTTKISFKEVVEAIGRNAFITSDMPIIISIENHCSLPQQ
RKMAEIFKNVFGDKLVTKFLFESDFSDDPMLPSPGQLKRKILLKNKKLKAHQTPVDILKQ
KAHQLAHMQAQASNGASNPTPTNEEEEDEEDEYDYDYESLSDDNILEDRPENKLSSDKLQ
FEYNEETAKRIKKADCATYNNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAV
KFPGLSTLNPSGSSRGKERKSRKSIFGNNPGRLSPGESATLAKASGKGPFDVMRQTWEDP
CSPYNSPASLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTTCQLLRTYPAATRID
SSNPHPLIFWLHGVQLVALNYQTDDLPLQLNAAMFEANGGCGYVLKPPVLWDKNCSMYQQ
FCPLERDLDNKEPAIYSLTIVSGQNVCPSNSTGSPCIEIDVLGMPMDSCHFRTKPIHRNT
LNPMWNEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHVQLHNLHNEA
LEISSLFINSRRMEENPSGNTLPASKLFSTGEKKAAAIYKVTIHGIPGPEPFTVFNISGG
TTAAQLLNQLLASTKGTESCAADYFLMEEKSFISKEKSECRKAPFQRVIGPEEGLVQLLN
SWFPEEGYVGRIIFKTREENLNERNILQEAKEDTAISSEDDSFFVQVHDVSPEQPRTVIK
APRFSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVTKEPANKKSSTPKPSQRILSD
QECVFQAQSKWKGAGKFILKLKEQVQAARDDKRKGISFTSELRKLTKSSKQYRGFISPPL
QALPDNPQSKDERFACSLTFSDIME
NT seq 6918 nt   +upstreamnt  +downstreamnt
atgacctctgaggatatcacagcgtctgttctcgtctctgtggtacagagtaaagtgata
cctgctcagtcagctggaaatgagaatactgaaaatgcttcggacaccagtgttataaaa
agacatactgccagtccgggaaggcagcccacacgtgctttctcatacttacacagactt
gaagaagaaagtcttcaggactcagtgcctgaaatattctctctggcgaaagaccaaatg
actaatgacagtactcatgaaaacttttgggagagggaaagctctatccctgattcagtg
gaatttcttaacattaactgtaacgttgtacagaaaaactgtgagaggaatatcccatgc
agccagttgtataaatcatgtgatccttccacagggggagaggcatgcctggaaactgga
aatcctgtttcactggaaagagccatgcttgctgaaattcagttgaaaatgaacggacct
tcgttaagaagccagacagcagtaaataagaacgacagcaatgatattgataaagtggcc
ttttttcactttcattgtgctagtgaaaagaatatctcaaaggccttgtgcagtttacac
aatgggttcattttggatgactgcttgcagccagtaagtgttggcgacggtaacaccact
ggttccctggcctgcgcttgcagactgatggagttgacaaataattgtgagaatgaaaat
gggcagcagttgtatgaaggtgctttaagggataagtacttatgtctggaaagagaacca
caaaaggataaagtggcatgcttaggtcccgacttctgtggaaataacttcactggaaga
atgccctcaaagccctttctgagccattttgaagactgtaatgataactgtgaagagatg
gaagaggatctttttagaaacaaaaaagaacgttctactttattaataagacgtttctgt
aaaaatgataaagaggttaaaaaatcagtttatactggaacaagagcaattgttaaaact
ttaccttcaggacacataggaaccattgcttggaattacgttgagcaaaggagaaacaac
agtggcttgaagatttctaggattacaacagaacagctcactgtaattcattccttaata
aaatgggaatttaattcctttcttgagaagtctttatggtatgagatcttcagcacagtg
agagaagatgaaggagaagatatttttgaatattttcctcatcttctgagaaagctccca
acatttaatacagactgtacatgcaaagatgatgggttttctgtaaaacaatgtgtaaca
ggtccttactgtcgatatcgtgccacttcacagaggactgcactctctaaatatataact
ggtgctttactagaagcaactacatcattaggagcaagaagtggtcttctaaatatcttc
ggaggatcatctggaagaacaatgcttaaagagcgtcaagcgtgtatgtctatggccggc
tccagcatctttccctccaacgtggctggtatcagcaaagagttgattgaactgcagcac
ctcatccagttcccagaggaggttgccagcattctgactgagcaggagcaggagctttac
cagaaagtcttacccattgactacctgtgctttttaaccagggatttgggtaatgctgaa
tgtcagagcaagctgccgtctattaaagcttccatatctgctactattctttcttccccc
aatggtgaacataatgctgtagaagatcttgtgacaaggtttaatgaggtgagctcatgg
gttacctggctgatcctgactgcgggttctatggaagagaaacgagaagtcttctcgtat
ttagtacatgtcgcaaaatgctgctggaatatgggcaactacaatgctgtaatggaattc
ctggcagggctaaggtcaagaaaagttttaaaaatgtggcagtttatggatcagactgat
attgaaactatgcgaagtctgaaagatgctatggcacaacatgagtcatcgtctgaatac
aggaaagtggtgaaccgggcactgaatattccaggctgtaaagttgttcctttttgtggt
gtatttttaaaagagctttgtgaagttctggatggagcatcaagcctcatcagactctgt
ccacgatataattcccaggatgaaacattagagtttgtttcagattacagtggacaagat
aatttcttgcaacgagtaggccaagatggtctaagtaatccagaaaaagaatcaacagca
aacaatatctttcaaactattcggagctgcaatcgcagtttagaatctgaagagggtgaa
gataattttagtgaagggagcaattcaagaaaaaactctttgaaggacaaaacccggtac
catgcagcacatgtaaagaaagcttctgattcaaaccaggttctatttataattggagat
ctttcggattctgaaagtgatatatttgagcagttgaaagaatgggacacaaattcaaca
gaagagcagcaaaaggctttctgccatgggatagaacttataccctggtacgtgttgtct
atcagggctgatgtccatcagttcatgcaacaaggagcaactgtcatccattacgatcaa
gagacacatctttcagcacgttgctttcttcaacttcaacctgacaatagtactttgact
tggacaaaacccacaacggtttgtcctgcaaatgctaaggcaaaactgagtgtgctgggt
agtagtgctgaacttggtaaataccagttgcttggtaatactggactggtggaaggattt
ttggacttgttttcagccaaggctgtatatatgggacactctggcattgatatgcacact
gtgtgtgttcaaaataaactttgtaatatgtcccttgaagaaaatggtgtaacgctactt
tatggacttcatactactgataataagttgctgcactttgttgctccaaaatatactgcc
agaatgctgtatgatggattgctggaattgactaaagctgtaagaaaaatgaggaggttc
cctgatcaaagactacagtggctacggaaacagtatgtcagcctttaccaggaggatgga
aggtttgaaggcccaaccttggctcaggctattgaactgtttggaggcagacgatggagt
gcaagaaacacaagcacgggaactctcaccaaaaacatggagaaagctagtgtacagaga
aacaacactctgggaataagcacagctaagaaaaagaagaaagtactcatgaggggtgaa
agtggagaggccactgatgatgaaatggcaactcgaaaggcaaaaagctgtaaggaatat
cgtaacagaagtggttcagatcctcaagatattgatgaacaagaagaaccagatcaaaat
attattattaatgcttgtccatctaacaacttgccatcaagaagagctcactctctgaca
gcatctggatctcctaatttaggagctacatcatcttcaccagccagaccagtttcctct
cctgtaatgtcttcaaacaagagtcagtctagcacatggagcagcagcagctggcatggc
cgtgttaaaggaggaatgaagggttttcagaacttcatggtgtctgatagtaacatgaca
tttgtggaatttgtagagctcttcaaatctttcagtgtccgtagccgcaaggatctgaaa
gacctttttgatgtctatgctgtgccttgcaatcgatctggtttggagcctgctccactt
tacactaatttgaagattgatgaaaatagcagtggattccagcctgatttagatttgttg
actaggaatgtttcagaccttggtttgttcattaagagcaagcagcaactatcagacaac
cagaggcaaatatctgatgctattgctgctgccagtattgtaaccaatggtactggagtg
gaaagcacatcactgggaatatttggagtgggaatccagcagctaaacgacttcctagtg
aattgccaaggagaacactgcacctatgatgaaatcctcagtataatccagaaatttgaa
cccagtgtgaatatgtgccagcagggactgctatcttttgaaggatttgcaagatttttg
atggataaagacaactttgcctccaaaaatgatgagtcgcaagagaatgctgaggacttg
aactttccactgtcatattactacatagaatcttcccacaatacttaccttactggccat
cagcttaaaggggaatcctcagtagagctgtacagccaggttcttttacaaggctgcaga
agtgtagaattagactgctgggacggcgatgatgggatgcctataatttatcatggccac
actcttactactaagatatcttttaaggaggtagttgaagctattggtcgcaatgcgttt
atcacctctgacatgccaattatcatatcgatagaaaaccattgttcattgcctcagcaa
cgcaagatggctgaaattttcaagaatgtatttggagataagctggtaacaaagttttta
tttgagagtgacttttctgatgatcccatgcttccttcacctggccaactgaaaagaaaa
atcctgcttaaaaacaagaagctcaaagctcatcaaacaccggtggatatattgaaacaa
aaggctcaccagctggcgcatatgcaagcgcaggctagcaatggtgctagtaaccccaca
cctaccaatgaagaggaagaagatgaagaggatgaatatgactatgactatgaatctctc
tctgatgataacattcttgaagaccgacctgagaataaattatcaagtgataaactgcag
tttgaatataatgaagagactgccaaacgaataaagaaggctgattgtgctacttacaat
aataaaggaaaggtttatgacatggagctgggtgaagaattctatcttccacaaaataag
aaggaaagtagacagatagccccagagctatcagatcttgtcatttactgtcaagctgta
aagtttcctggcttgtcaactctaaacccatctggctctagcagaggaaaagaaagaaaa
agcaggaagtccatttttggcaacaatcctggcaggctgagccctggggagtcagctact
cttgccaaagcatctggaaaaggtccttttgatgtgatgcggcagacctgggaagatcct
tgctctccttacaactctccagcttctctcagtgctatcataaggacgcccaagtgctat
cacatctcctccctgaatgagaacgctgccaagaggctgtgcaggcggtactctcagaag
ctgatccagcacaccacctgtcagcttctgaggacctaccctgctgccacgcgcattgac
tcctcaaatccccatccactgatcttttggcttcatggcgtacagctcgtggctcttaac
taccaaacagatgatcttcctctgcaacttaatgcagctatgtttgaggccaatggtggc
tgcggatatgtgttgaaaccacctgttctgtgggataaaaattgttccatgtaccagcag
ttttgtccgctagaaagagaccttgataataaagagccagctatatattctttaacaatt
gtgtctggacagaatgtctgccctagcaatagcacgggcagtccgtgcattgaaattgat
gtgttggggatgcctatggatagctgccatttccggacaaagcccattcatcgcaacact
ctcaaccctatgtggaatgaacagttccttttccgggttcactttgaagatttggtcttt
cttcggtttgccgttgttgaaaataacagctcagctgtaacagctcagagaatcattccc
ctaaaagctctaaaaagaggctatagacatgtccagctccataacctgcacaatgaagca
ttagaaatttctagtttgttcataaacagtcggagaatggaagaaaatccttctggaaac
actctgcctgcatctaagttgtttagcacaggggaaaagaaagctgctgccatttacaaa
gtgacaattcatggaattccaggcccagagcctttcactgtttttaatataagtgggggg
acgacggctgcacagctcctcaatcagctcttggcttccacaaaaggcaccgagtcatgt
gctgcagactattttctgatggaagagaaaagtttcatatctaaagaaaagagtgaatgc
agaaaagcaccattccagagagtgattggtcccgaagaagggctagtgcagcttttgaac
agttggttcccagaagaaggatatgttggaaggattatctttaaaacccgagaggaaaat
ttaaatgagagaaacatccttcaagaagcaaaggaagatacagccatcagctctgaggat
gacagtttctttgttcaggtacatgatgtctccccagagcaaccacgcaccgtcatcaag
gctcctcgctttagcacagctcaggatgtgatacagcagactctttgcaaagccaaatac
tcctacagcattttgagcaatccaaatccaagtgattatgtgctcttggaagaggtgaca
aaagagccagcaaacaaaaagtcctcaacaccaaaaccatctcagaggattctctctgat
caagagtgtgtgtttcaggcccaaagcaagtggaagggagcaggaaaatttatcctcaaa
ctcaaggaacaggttcaggcagcacgagatgacaaaagaaaaggcatttcctttaccagt
gaactcaggaagttaacaaagtcaagtaagcagtatcggggattcatctcgccccctctg
caggccttgccggacaatccacagagcaaggatgaaaggtttgcgtgcagcctgactttt
agtgacattatggagtaa

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