Cuculus canorus (common cuckoo): 104068728 Help Entry 104068728         CDS       T08597                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism cuca  Cuculus canorus (common cuckoo) Pathway cuca04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:cuca00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     104068728 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:cuca03036]     104068728 (SYNE1) Chromosome and associated proteins [BR:cuca03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     104068728 (SYNE1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Spectrin_SYNE1_2 ATG17_like Motif Other DBs NCBI-GeneID:  104068728 NCBI-ProteinID:  XP_053918204 LinkDB All DBs Position 3:50438322..50759016 Genome browser AA seq 8828 aa AA seqDB search MASSRLVARSRDIANVMQRLQDEQESVQKRTFTKWINTHLAKRNPPMLVNDLFEDIKDGV MLIALLEVLSGQKLPCEQGRHLKRIHWVANIGTALKFLEGRRSIYRGSPIKLVNINSTDI ADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLSSSASSVESVVSSETASPPSKRKVVT KVQGSARKALLKWIQYTAAKQVGLEIKDFGQSWRSGVAFHSIIHAIRPDLVDMEKVRGRS NRENLEEAFTLAEAELGIPRLLDPEDVDVDKPDEKSVMTYVAQFLKYYPDPHHVVTDAQE NDELQAIPTFVISFMKFKKEDRLMLRDLKVWAEQFERDLTRAQVAETSLQEKYQSFKHFR VQYEVKRKQIELVTQSLRKDGKLSLDQAMVKQAWERVSSRILDWHIYLDKSLPAPLGTIG AWLYRAEAALREEVTVQQAHEETANIIHRKLEQHKDLLKNIDGHKKAFHEIHGARSVNGV PVPVDQLEDMAERFNFVVSSSELHLLKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRES VELLLQNYISVIENSKFFEQFEVTYQILKRAAEMYAKANGSVEEVESVMKFMNETTAQWR NLSVEVRSVRSMLEEVIANWDRYSSTVAGLQAWLEDAEKMLNQPEHSKKDFFRHLPHWIQ QHTAMNDAGNFLIETCDETISRDLKQQLLLLNGRWRELFVQVKQYARADELEKMRKEYLD GVAHLTAFVDESNRKFSVPVEVSFLDVKMFVQDLENIKQKLPAMEAQYKMVTRTAQLLTK EVAQEEVNEMLGTLARIKEQLGKVKDYSCALVYECQRLLSPLEELEKQITHFYESLEKVN EIISILDPEAQPTTVLKQKAQDLVAYQENCKKDVSLIERNSQSILQCVASSEVLRHFHQS TFQKKVTQVQITFQNMVRKAGDWRKNIEANSRLMKKFEESRAELEKVIQIANCCLKEKGN PEELLRKHSEFFNQLDQRVLNAFLKACDELTDILPEQEQHSLQEAVRKLHRQWKDLQTEA PYHLIHLKIEVQKSKFLVTVEECKAELARQNKVLSREGNERMIKEHMLFFGDKGPYQLCE KRLQRIEELCQKLPVTDPVRAALETSQRILKDLKFQIDSTYIKLTEHSDTWKGYKNRFSE LASWISSTERELKKIKESVNDTTKYKQFKTSVGEIRKHINKQGENHSWLKSTLAVLTAVC PDLEAKKTEDELCKLSSDFKGLLDLLAEIEKTLGAVGDCVQYKEEVKSAIEELINNSKEA QAEAEKILDTESLLQAQQLLLHHQQRTRRLRAKRQDVQQQISQAKQLQVAGGLPSTMQED LQKLEGTLENMQQTMEKREEQLQVTINKWEQFEKDKETVVRYLNQASCALERILNFSSLE SLSSELDQTKELSKQTEAMAVQAENLVKNSSEIQLGSKNKQSLQQQAKSIQEQVKKVEAT LEEDIKSMEMVKNKWDHFGNNFEALSIWIAEQEKELGTMETSSSPLDIQISQIKVINKEI DGKITGISELEEEAKSFSQFVTSGECAHIKAKLTQVKRYWEELRDHAQRLEGAITENASA QQKYEESLKQVQRAVSEFEAKVAEPLTSCSSSSATYAALQDCTDLCHTVEKLSNTLASLT ACARKVASKEKAAQEVTALQQKYEKLLVNAKEKQTLLETLLAQWQKQEKELSAFLTWLEG CEATARPSEQYVSSDRVKLEVELQSLQDLRADIESHTSVYDSLLQLNESLFPTASKQSVK TIKEKFEELDDRWKALPQTLDKRINFLQSLVAEHEQFDELLLRFSDWIKQFLAELQATSE IKTADQQLAASHNKKHLMEVESKKQQLQSLKKHVDKLCSFSCPEDQQTLQGKTEDCFQIF QEASQITCQRQEALDQLRVFLELHNAVSVVLHHLRQTVEKTGNIDKAKSELLEKELNDVI QDLNKLESVAISLDVSLTKAQYHLKHSSSEQRTSCRAVVDNLCLDMEAVQNLLGTKQSEA EALGALRKSFMERKKQLLKSIEDTEEKADKEGLKEATLQALQQRLRIFNQLDEELNSHQH ELQWLRDKAKQIAQKDITLAPEINKEVNRVESLWEDTKKVINEKKEQSGILIDLMKEYQC LKSTIMKVIDSADSATMIKSIWKDREDVRRTLSKHAAAKNDLSDKQKDLDTFTNKGKHLL AELKRIHNCDSTAVKTDMNCTVDKWLDVSERIEDNIDRLSVTVSLWDEILKTGEEMDVWC NKCISQLDEGISNLSNSQRMEVLLKEFQSDVKDKELKLEQLHSKISDLKELTHSQEPPAD LQFIESDLRQKLEHAREMSETAKETLKDFSAQRMQLQKFIDQMTGWLKKVEETLLSCSCN LDPEALNKVKETQKDLQLQQSTIDSARENLNSLCRKYHSVELETLGGTVTSLIKKYEAVN LLCSRTQASMQESLEKHFLYSMQEFQEWFSGVKAAVKESSDRSGDSKAIEAKLHDLQSVL DSVSEGQNKLDVACKEGQSLYTCLPKPLVSNIQEQIARSNQDLQEFLNQCLNDKKALEAC ASYLGSFEDQHKKLGLWLRDMEERISTEALGESKQLIPEKQKEVQKVEQFLEELLNSRES FDKLSQMAQTLNDEGQGEGKEVRLASQHLTDYQNMVKTVKEKLRTCQLALQEHLTFEEAL QSMWSWVKEVQDKLASSESTVGSKATLEKRLAQIQEILLLKGDGEVKLNMAIGKGEQALR SSNEEGQKVIQSKLRTLKDVWNDVISTSVNWQSCLESVISQWNEYLERKNQLEQWLEKLD HQVEQPLEPQIGLKEKFAQLDHFQAIVSEIENHSGDLHQLIEKAVEMYEKTEDCSFGEAA QEELKSQFNDITTVAKEKMRKVEDIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDASGDT STIQKKLAKINELVESRQLGADRLGRVETLAPAAKRNTSAGGCQLLAAEMQGLRAEWKEW EESAFRSRSSLRDVLSQMALSEQEFAAQVERLEAAAERFGALLAAWSRSVEPLDSRHTDA ELVESWRKEKETMDALVKSEHMTDELKTQLNHLCRFSRDLSTHSSKVSGLIKEYNSLCLQ ASKGCQSKEQILQQRFRMALRDFQQWLVNAKVATAKCFDVPQNISEVSASLQKIQEFLSG SENGQQKLNLVVSKGEMLCAVLPKEKAKVIQDKSAATKEDWKNFITTLHQKESALENLKI QMKDFEATAEPLQEWLTATEKVVQGSSSRLLDLPSKRREQQKLQSVLEEISCHEHQLNRL KEKAQQLWEEQAVSKGFMRRVSQLSSQYLTLSNLTKEKVSRMDRVVAEHQQFSCSVKDLQ DWVADAVHMLDSYCHPTADKSVLDSRMLKLEGLLAVKQEKEIQMKMVLTRGESVLQNTSL EGIPVIERQLQTLKDNWASLLSACIQCKSQLEGALSKWTSYQDDVRQFSNWMDKVEASMN ASERQYAELREKTAALSKAKLLSEEVLSHSSLLETIEMKGSGMAEHYVTQLELQDLQERY KFLKDRTREAVTKAEGLLKLHQEYQRNLKAFEVWLEEEQEKLDCLSHLDGDAQKQEATLR DLQELQVHCAEGQALLNAAVHAREEVIPWGVPQIEDRALESLRQDWQVHQHRLSEARSQL NATVSRLRLMEKKIQKVNDWLTDLEKKVAIRTGRQSGRATKEMQLQQMKKWHEEIAIYKD DVEEVGVLAQQILEESLTASNMGSQATQLTSRYQTLLLHVLEQMKFLEEEIHCIEESELA FSAYTDWYGATNKNFGNVITKFDMVDKTAMEKKVQKLELLLNDMDIGHSLLKSAREKGQR AINYMEETEADQLRKEIGDHMEQLEELAGSIRKEHSTSEKCLQLAKEFSDKYKAQTQWLT EYQAMLHAPAELKSELYEKKAQLSKYKSIQQTVLSQEPSIKSVIEKGEALFDLVKDVTLK NKIQDLQSTYEEFCSTTKAYVETLEVRVKEHEDYNSDLQEVEKWLLHMSSRLVNPDLMES NNLEIITQQLANHKAIMEDISGFEDRLNNLKSKGDHLINQCTEHLQAKFKQNIQSHLQGT KDSYSAICSTAQRVYQSLEHELQKHVNRQDTLQQCQTWLSTVQSELKPTTWPPFSLADAV KQVKHFRALQEQANTYLDLLCSMCDLSDATVKRTATDIQQTKQTIEQQVMHSQFLAQGWE EIKQMKAELWMYFQDADQQLQNLKRRRAELELNIAQNMVLQVKEFSQKLQSKQSALTSVT EKMNKLTQGQESPEHKEIGELSNQWLDLCLQAHSLLIQREEDLQRTGDYHDRMNVVEVFM EKLTKEWDNLARSDAESTNMHLEALQKLSAALQERRFALEDLKDRKQKMIEHLNMDDKEL IKEQYGHFEQRWTQLEDLVKRKIQVSIWTLEELSLVRSKFQELMEWAEEQQPSMSEALKQ SPPPDLAQSLLMDHLTICSELEAKQLVLKMLVKDADRVMTNLGLNERQELQKALSDAQHH LDCLSSLAGQRRKHLNKALSEKTQFLLAVFQATNQIQQHEKKVTFPEHICLLPEDVNKQI RTCKNAQANLKAFQNELTGLWAQGRDVMKEATEQEKSEVLGKLQELQNVYDTVLQRCNQR LLELEKNVVSRKYFKEDLDKACHWIKQADIVTFPEVNVMNSNSELYTQLAKYQQILEQSP EYENLLLALQRDGQEILPSLNEVDHSYLDEKLKILPQQFNIVTALAKEKLYKVQEAIYAR KEYASLIELTSKALNELEDQFINMDKAPSAVLAKEVLSLQQAYKDLLGEVVSLGAAVDEL NQKKEAFRSTGQPWQPDEMLKLVALYHKLKRQIEQKISLLEDTVEACQKHEKMCMQFEAQ LEAVKMEQIKVNEETLPIEEKLKIYHSLVGNLQDSGSLLKQITEHLEALSPQLDSSAYET TNHQVQSWQEKLKSLHATIGDIVMECENRLVQSIDFQTEICRSLDWLRWVKTELNGTLSL DLKLQCIQEEIRKVQIHQEEVQSSLRIMNALSNKEKEKYMKAKELIPADLENTLAELTEL DSEVQEAIHMRQATLNKLYSLCQRYYQVMQIANDWLEDAQEFLHLARNGLDVENSEENLR NHIEFFSTESQFSGHLKELQGLVSEIETFIQATAREQLVQSVAALEEKAKGTKQEAKTQQ EQLQRCASEWQEYQAARQKVIEVMNEAEKKLSEFSVAKAASSHEAEEKLITHKTLVSVVN SFHEKITALEEKASQLEKVSNDASKATISRSMTTVWQRWTRLRNVAQEQEKILEDAVQEW KAFNDKIQKATVAIDELQGRLPESSVEKASKAELLELLDYHSSFFLEVEHRLSSISLLKQ HAVSMLQDVEIKPLSQEELPVMQEIKAVQDRCHNMQQKVKKGVKMVKQELKEREEVEAEI NIVQSWIQETKEYLLSPDAEVDTQLQELQSLLGEVTAHRQAVEKMAEQQQNKYLGLYTVL PSELSLHLAEVGLALVTVQDQIQTKEKETQRIKTLNQEFGEKIQGIANELNAILSKLKKK TNDIAQAKLEQKILGEELDSCNIKLLELDASVQDFAEQNVPLAKQLANRIGKLTALHQQT IRQAEYRAAKLSQAASHLEEYNEMLEFILKWIEKANILVHGSITWNSSSQLRDQFKAYQT MLDESGEIHGDLEAMMERIEYLASVYCTETMSQQVLELGRRTEELQQVIKARIPSLQDAA KDMKKFEVELRALQTALEQAQATLTSPELGHLSLKEQLSHRQHLLSEMESLKPKVQAVQV CQSALRIPEEVVTSLPMCHSALQLQEEASRLQHTAIQQCNILQATVVQYEQYEQEMKHLQ QMIESAHREIQDKPIATSNIQELQLQISHHEELAQKIKGYQEQISSLNSKCKMLTMKAKH ATMLLTVTEVEGLSEGMEELDTDLLPAHPTHPSVVMMTAGRCHTLLSPVTEESGEEGTNS EISSPPACRSPSPVANTDASVNQDIAYYQALSAEQLQTEAAKIQPSTSATQEFYEPGLEP AASAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDTLQSISTKMETIETKLNESLE PAKSPESQMAEHQALMDEVLMLQEEITELQTSLAQELVSEPLDAEGADQLALQSTLMVLA ERMATIRMKASGKRQLLEEKLNEQLEEQRQEQALQRYRCEADELDHWLLNTRATLDTALG AAEEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNENLLMEGKAHTKDEAEQLAMKLRT LKGSLLELQRVLHDRQINIRQGSLQEKEESDLDFVSLQSPSVQEWLAQARTTRSQQQQSN LQQQKELEQELEEQKNLLRSVACRGEEILTQKGAPEGLHISEKPDTLSEELGLEGEKPSS EEQMKVKWESLSQEFNTKQRLLQKALEQEQLQLYGRPNRLISGMPLYKEEEHDKDKSSVS PVWIELNQAFEDLSSEAGRVEESLHVEQMLYDGVTATSLWLNGVEEQVFAATALLPEEET ETYLCQQESLAKEIKDITEEMDKNKNLFAQMFPEDGGNKNIIEDTLDCLLKRLTLLESVV DQRCHQMKGHLQQIVTFKNDLKLLLASVADNEYLVLHKLAEAVEGPETEQMQVILQAEEG LKELDAGINELKKRVDKVQIDQPSVQELSKIQDKYDELIKIVGSRRSDLNQNLALKRQYE RALQDLADLVETGKEKMAGDQKIIVASKEEVQSLLDKHKEYFQGLESHMILTETLFRKMS NFALLKETQSHSELLTQASAVLKLAHKRGVELEYILETWVHLDEDYQELTRQLESVEGSI PTVGLVEETEDRLTERITLFQHLRSNLTEYQPKLYQVIDDGKRLLFSVSCSDLESQLNQL GEHWLSNTSKVTKELHRLETILKQWTRYQSESNELTHWLQSAKDRLEFWSQQSLTVPQEL ETVRDHLNSFLEFSKEVDAKSSQKSSVLSTGNQLLKLKKVDTAALRAGLSHIENQWTELL AQIPAVQEKLHQLQMDKIPSRHAITEVMSWISLMENVIQQDEENIKNVVGQKAIHDYVQK YKGFKIDLNCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNRRWQILQSLLTE KIQMLESLQESWTEYENNVQCLKAWFETQEKKLKEQQKIGDQASVQNALKDCQELEESIR TKEKEVENVEQSGLSLIQNKKEEVSSAVMNTLQEINHSWASLDHMVSQLKTLLQTVLDQW NIYKKAYEELNSYLTEARYSLSRFYLLTGSLEAVKVQVENLQSLQEELEKQENSLQKFGS VTNELVKECHPPVTETLTNTLKEMNMRWNNLLQEIAERLRASKGLLQLWQRYKDCYQQCS STVRQREDQTNELLKTATSKDIADDEVTTWIQNCNDVLTDLKTAQESMVVLQELGEELKS QVEASAAAAIQSDQLSLNQNLATLEQALCKQQAVLQAGVVDYQTFAKNLQVLEAWITEAE EILKGQDPSHSSDLSAIQSRMEELKSQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQT LNRHWSLISSQTTERFSKLQSFLLQQQTFLEKCETWMDLLVQTEQKLAAEISGNYQSLLE QQRTHELFQAEMFSRQQILHSIISDGQRLLEQGQVDDREEFNLKLTLLSNQWQGVIRRAQ QRRGIIDSQIHQWQRYREMAEKLRKWLVEMSCQPVSGLENVPIPLQHARALLDEVQLKEK VLLRQQGSYILTVEAGKQLLLSADSGAEAALQTELTEIQERWKIASTQLEHQKKQLALLL KDWEKSEKGIGDSLEKLRSFKKKLSQPLPEHHDELQAEQIRCKELENAVEGWTDDLAHLS LLKETLSIYISADDISILSERIELLHKQWEELCHQVSLRRQQVSERLNEWAVFSEKNKEL CEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQKNKIQLQQMGERLAKASHESKA SEIEYKLGKINDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRSWLAHIESELSKPI VYETCESEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATEAECDSIQQA TRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKTSERTAAFPSSSGVLY TVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSDCSLKQMVHEGNQRWDNL QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAF QQEILLNNNKIEQIIVQGEQLIEKSEPMDAAVIEEELDELRRYCQEVFGRVERYHRKLIR LPLTDDEHDLSDKEVDLDESGDLSDVHWHEKSMDNILSPHPSSNLSLPLSQPVRSERSGR DTPASVDSIPLEWDHDYDLSRDLETAVSRALHSEEEDRAQEKDFYLRGAAGIADVEIPET LEAYVTLTENALKTVSGDPGALEAHMRQLDKALDTSRFQIQQTENIIRSKTPTGPELDSS YKGYMKLLGECSGSIDSVKRLGYKLKEEEEKLSGLINLNSTETQTAGVIDRWELIQAQAL SKELRMKQNLQQWQQFNSDLNNIWAWLGETENELEKLRHLDLSTDIQTIELRIKKLKELQ KAIDNRKAIILSINLCSSEFTQSDSEETKKLQERLSQMNVHWDHVCSMIEEWRCSLQDAL MQCQDFHEMSHGLLLWLENIDRRKDEIVPINPNLDAEALQDHHRLLMQIRRELLESQLKV ASLQDMSCQLLVNAEGKDCLEAKEKVHVIGNRLKLLLKEVTRHIKDLEKILDISSNQLEL SSWSSADELDTSGSVSPVSGRSTPSRQRTPRGKCSLSQPGPSVSSPHSRSTRGGSGSSPS EARPAWHRLSFFLRVLRAALPLQLLLLLLIGLACLVPMTEEDYSCTMANNFARSFHPMLK YMNGPPPL NT seq 26487 nt NT seq  +upstreamnt  +downstreamnt atggcttcatcccgactagtggcaagatctagggatattgccaatgtcatgcaacgactt caagatgagcaagagtcagtgcagaaaaggacttttacaaaatggatcaatactcacctg gctaagcgcaatcctcccatgctggtgaatgatctgtttgaagatatcaaagatggggtg atgctaattgcccttttggaggttctttcagggcagaagctgccttgtgagcagggacgt catctgaagagaattcactgggttgccaacattggcacagctcttaagtttctagaagga agacggtccatatacagaggatctccgattaagcttgtcaacataaactcaactgatatt gctgatggtaggccttctattgtacttggactggtgtggaccataattttgtattttcag attgaagagcttactagcaacctcccacagctgcagtcgttgtctagcagcgcttcttct gtagagagtgttgtcagctcagaaactgcaagtcctccaagcaaacggaaggtggtaacc aaggtccaaggaagtgccaggaaggctttgttgaaatggatacagtatacagcagcaaag caagttggacttgaaataaaagattttggacaaagttggaggagtggcgttgcatttcat tccattattcatgctatccgcccagatttagttgatatggagaaagtgaggggaaggtca aatagagaaaacctggaagaagccttcacacttgcagaagcagaactgggaattccacgt ctccttgatccagaagatgtggatgttgacaagccagatgaaaagtctgtcatgacctac gtagcccagtttttgaagtactatcctgatcctcatcatgtggtgactgatgcgcaggag aatgatgaacttcaagcaatcccaacttttgtcatttcttttatgaaatttaagaaggaa gacagactgatgctgagagacctaaaagtgtgggcagaacaatttgaaagagacttaacc cgagcacaggtggcagaaacaagcttacaggagaaataccagtcatttaaacatttcaga gtacaatatgaggtaaaaaggaaacagattgaacttgtaacccagtcattaaggaaagat ggtaaattgtcacttgatcaagctatggtgaagcaagcatgggagagagtttcttccagg atactagattggcacatataccttgacaaatctcttcctgcacctttgggtactataggt gcttggctttatagagcagaggctgctctgagggaagaagtaactgttcagcaagctcat gaagaaacagcaaacataatacacaggaaacttgaacaacataaggatctgctgaaaaac atagatggtcacaaaaaggcattccatgagatccacggggccaggtctgttaacggagtg cctgttcctgtggaccaattagaggatatggcagagaggtttaattttgttgtatcttca tctgagctccatctgttgaagatggagtttctggaactgaagtaccgtctactgtcactg ttagtccttgcagaatcaaagttaaaatcgtggattatcaagtatggaaggcgagagtca gtggaactacttcttcaaaattatatttctgttattgaaaatagtaagttctttgagcag tttgaagttacataccagatcttgaaaagagcagctgaaatgtatgccaaagcaaatggt tcagtggaagaagttgagagtgtgatgaaattcatgaatgaaacaacagcacagtggagg aacctctcagtagaagtgagaagtgtaagaagcatgttggaagaagtgattgctaattgg gacagatatagcagcactgtggcaggtctacaagcttggttggaagatgctgaaaaaatg ctgaatcagcctgaacattctaaaaaggatttcttccggcacttacctcattggatacaa cagcacacagccatgaatgatgctggtaattttctgattgaaacatgtgatgagaccatt tccagagaccttaaacagcaacttctgttgctaaatggaagatggagagaactgttcgtg caagttaagcagtatgctcgagcagatgaactggaaaaaatgaggaaggaatacttggat ggtgttgcccatttgacagcttttgttgatgaaagcaataggaaattttcggttcctgta gaagtgtccttccttgatgttaaaatgtttgtacaagatttagaaaatattaagcagaaa ttgcctgccatggaagctcagtacaaaatggttacaagaactgcacaacttcttacgaaa gaagttgcacaagaggaagtcaatgaaatgcttggaactttggcaaggatcaaagaacag ctgggcaaggttaaggactattcctgtgccctggtgtacgaatgccagcgtctactgtct ccactggaagaactagagaaacaaatcacacatttttatgaatctcttgaaaaagtcaat gaaataatttctatcctggatcctgaagcacaacctacaactgttcttaaacaaaaagcc caagatttggtagcttaccaagaaaactgcaagaaagatgtgtccctgattgagagaaat agtcagagtatcctgcagtgtgtggcttcaagtgaagtgttaaggcatttccatcagtca acatttcagaagaaagttacacaagttcagattacttttcagaatatggtcaggaaagct ggtgactggagaaaaaacatagaagcaaatagccgtctgatgaagaaatttgaggagtct agagcagaactggagaaagtcatacagattgcaaattgttgcttaaaagaaaaaggaaat cctgaagaacttctcaggaaacatagtgaattctttaatcagttggatcagagagtccta aatgcctttctgaaagcatgtgatgaacttactgacatcctcccagaacaagagcaacat agcctgcaggaagctgtgagaaaactacataggcagtggaaggatcttcaaacagaagcc ccatatcatttgatccacttgaagattgaagtacagaaaagcaagttcctggtcacagtg gaggaatgcaaagctgaactagctcgacagaacaaggtgttatcaagagaaggcaatgaa aggatgatcaaggaacacatgttgttcttcggtgacaagggaccttaccagctgtgtgag aaaaggcttcaaaggattgaagaactgtgccaaaaactcccagttactgatccagtgagg gctgcattggaaactagccagagaatcctgaaggatctcaaattccagatagacagcact tacataaagctaacagagcactcggatacttggaagggctataagaacagattttctgaa ttggcaagttggatttcatcaactgaaagagagctaaagaagataaaggaaagtgtcaat gatactaccaaatacaagcaatttaaaacatctgtgggggaaattaggaagcatattaac aagcaaggagaaaatcacagctggctgaaatctacacttgctgttttgactgctgtctgt cctgatttggaggctaaaaagacagaggatgagctttgtaagctttccagtgacttcaag ggactcctagatttgctggctgagattgaaaaaacattaggcgctgttggagactgtgtc cagtacaaagaagaagttaaaagtgcaattgaagagttaattaacaactctaaagaagcc caagcagaagctgaaaagatcctggatacagaaagtttattacaagctcagcagctacta cttcatcaccagcaaaggacaaggagactccgtgcaaagaggcaagatgtgcaacagcag atttcccaagctaagcagttgcaggttgcaggtggactgcccagcacaatgcaagaggat ttacaaaagttggaaggaacattggagaacatgcagcagactatggagaaacgtgaagag caactgcaggtcacaataaataaatgggaacagtttgaaaaggacaaagaaacagtagta agatatctcaatcaagcaagctgtgctcttgaacgtatcctaaattttagcagtttagag agcctctcctcagaactggatcagacaaaggaactttctaaacagactgaagcaatggca gtgcaggctgagaatttggtgaagaattcttctgagatacaacttggttcaaagaacaaa cagtcccttcagcagcaggccaaatcaatccaagaacaagtgaaaaaagtggaagctact cttgaagaagatattaaaagcatggaaatggtgaaaaacaagtgggatcattttggcaat aattttgaagctctgtccatctggatagctgaacaagaaaaagaactgggaactatggaa acatcatcatctcctttggacatacagatcagccaaatcaaggttattaataaagaaata gatggtaaaataactggaatctcagagctagaagaggaagccaagtctttttcacaattt 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tattttcagggattggagtctcatatgatcctgacagaaacactctttagaaagatgagt aactttgccctcttgaaggaaactcagtcacattcagaactattgacgcaagcatcagct gtattaaagctggctcataaacggggtgtggagctggaatatattctagagacctgggtg catctggatgaagattaccaggaacttaccagacagctggagtctgttgaaggtagcatc cccactgttggtttggtggaagagacagaggataggcttacagaacgtattacgcttttt cagcatctgagatctaatctgactgaataccaacctaaattataccaagtaatagatgat gggaaaagactccttttttctgtcagctgctctgatctcgaaagtcaactgaaccaacta ggagaacattggttaagtaacaccagcaaggttaccaaggagcttcacaggctggagaca atactgaagcaatggacaaggtaccagagtgaatcaaatgaactgacacattggttacaa tctgcaaaggaccgacttgagttttggagccagcagtctttgacagttcctcaggaactg gaaacagtccgagaccacctgaactcatttttagagttttcaaaagaagtggatgctaaa tcatcacagaaatcttctgtcctgagtactggaaaccagcttctcaagctgaagaaggta gacacagcagcactgcgtgcaggattgtcccacattgagaatcagtggacagagctgctc gcacaaatcccagcagtacaagagaaattgcaccagctccagatggacaaaattccttct cgccatgctatcacagaagttatgagctggatttccctgatggaaaatgtcattcagcag gatgaagagaacataaaaaatgtagtaggacagaaagccattcatgattatgtccagaag tacaagggtttcaagatagacttaaattgcaaacaattgacggtagactttgtgaaccaa tcagtgctacagattagcagccaggatgttgaaagtaaacgtagtgacaaaactgatttt gcagaacaacttggagcaatgaacagacgttggcagatcctacaaagcctactaacagaa aagatccagatgttggaaagtctgcaggaatcctggacagaatatgaaaataatgtacag tgcctaaaagcttggtttgaaacccaggagaagaagctgaaagagcaacagaaaatcgga gaccaggcttcagtacagaatgctttgaaagactgtcaggaattagaagaatcaataaga acaaaggaaaaagaagtagaaaatgtagaacagagtggtctttctttgatacagaacaag aaggaagaagtgtcttctgctgttatgaatacactgcaagaaattaaccattcctgggcc agtttagatcacatggttagccaactgaagacattattgcaaactgttcttgatcagtgg aacatctacaaaaaggcatatgaagaactgaacagttacctgacagaagccagatattct ttgtcccgtttttatcttcttactggttctttggaagctgtgaaagtccaagttgaaaac cttcagagcctacaagaagaattggaaaagcaagaaaatagcttacagaaatttggttct gtgaccaatgaattggtgaaagaatgtcacccaccagtgactgaaactcttaccaacact ttgaaagaaatgaatatgaggtggaacaaccttctgcaggagattgcagagcggctgcgt gccagtaagggcctccttcagctgtggcagaggtacaaggactgctatcagcagtgctct tccacagttcgtcagcgggaagaccagaccaatgaacttctgaagaccgccaccagcaaa gacattgctgatgatgaagttactacttggattcagaactgcaatgatgtactcacggat ttgaagacagcacaggagtcaatggttgttcttcaagaactgggagaggagctaaaaagc caggtggaggcttcagcagcagcagctatacaatctgatcagctttctctgaaccagaat ctggcaactctagaacaggctctctgcaagcaacaggctgtacttcaggctggagtggta gactatcaaacctttgccaagaacctgcaagtccttgaggcctggataacagaagcagaa gaaatattgaaaggacaggatcccagtcactcatctgatctctcagcaatacagagtagg atggaggaactcaagagccagatgttgaagttcagtagcatggccccggatttggaccgt cttaatgagttgggttacaggcttcctctgaatgataaagaaatcaaaaggatgcagacc ctgaacagacactggtctctcatttcatctcagactacagaaagattcagtaagctgcag tcttttttgctgcagcagcagaccttcttggagaaatgtgagacttggatggatttatta gttcagactgagcagaagctggcagcagagatttcaggaaactaccagagccttttagag caacagaggacacatgagctattccaggcagagatgttcagccgccagcagatcttgcat tcaattatctctgatgggcagcgcctcctagaacaaggacaggtggatgacagagaggaa tttaatctgaagctcactcttctaagtaatcaatggcaaggagtaattcgccgggcacag cagaggagggggatcattgacagccagattcaccagtggcagcgctatagggaaatggca gagaagctgcgcaagtggctggtagaaatgtcctgtcaaccagtcagtggcctggaaaat gttcctatcccattacagcacgccagagcactattggatgaagtgcagcttaaagagaaa gtactcctaaggcagcaagggagctatatcctcactgtggaagctgggaagcaactgctg ctctctgctgacagtggagctgaggcagccctgcaaacagagcttaccgaaattcaggag cgctggaagatagctagcacacaactggagcatcaaaagaaacagcttgctttactactg aaagactgggaaaaatctgaaaagggcataggagactccctggagaagttaagatcattc aaaaaaaagctttctcagcctttgccagaacaccacgatgagttgcaagcggagcagatt cgctgtaaggagttagagaatgctgttgaaggatggacagatgaccttgcacacctctct ctgctgaaggagaccctgtctatttatatcagcgcagatgatatctcaatcctcagtgag cgcatagagcttctgcacaaacagtgggaggagctgtgccaccaggtctccttacgtcga cagcaagttagtgagagactgaatgagtgggctgtcttcagtgagaagaacaaggagctc tgtgagtggctgacacaaatggaaagtaaagtttctcaaaatggcgacatcctcatagaa gaaatgattgagaaacttaaaaaggattatcaagaggaaattgctgttgcccagaagaac aaaatccagctccagcaaatgggagagcgacttgctaaagccagtcatgaaagtaaggca tcagaaattgagtacaaacttggcaagatcaatgacaggtggcaacatctcctagatctt attgcagccagggtaaaaaagttgaaggagaccctcgttgcagtgcagcagctggataaa aacatgagtagcttgagatcttggcttgcccacattgagtcagagctgtccaaacctatc gtctatgaaacttgtgagtctgaggagatacaaaggaaactaaatgaacagcaggaactt cagagggacatagagaaacacagcactggagtggcatctgttctcaatctgtgtgaagtg ctgctacatgactgcgatgcatgtgccacagaagcagagtgtgactctatccagcaggct acgcgtaatttggaccgaaggtggaggaacatttgtgcaatgtcaatggaaaggcgactt aaaattgaagagacgtggcgtctatggcaaaaatttttggatgattactctagatttgaa gactggctaaaaacctctgagaggacagctgctttcccgagctcctctggtgtgctctac acagttgctaaggaagaactgaagaaatttgaggccttccagagacaagtgcatgaaagt ctgactcagctggaactgatcaataaacaatatcgccgcctggcccgagagaaccgcact gactctgactgcagcctcaagcagatggtccatgaggggaatcagagatgggacaactta caaaaacgagttacatccatcctgcgcagactaaaacattttattggtcagcgtgaggag ttcgagacagcacgtgatagcatcctcgtatggctaacagagatggacctgcagctgact aacattgagcatttctcagagtgtgatgtccaagctaagataaagcaacttaaggctttc cagcaagaaatcctattgaacaacaacaaaattgagcagataattgtacagggtgagcaa ctcattgagaaaagtgagcccatggatgcagctgtcattgaagaagaattagatgagcta cgtcgttactgccaagaggtctttggacgtgttgaacgctatcacaggaaactcatccgc cttcctctaacagatgacgaacatgacctctctgacaaagaggtggatctggatgaatca 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cactgggaccatgtatgcagtatgattgaagagtggcgctgctcattgcaagatgcatta atgcagtgccaggatttccatgaaatgagccatggtttgctgctttggttagagaatatt gacagaagaaaagatgagattgtgcccatcaatccaaacctggatgcggaagcactgcag gatcatcacaggcttctaatgcaaatcagacgtgaacttctggagtctcagctgaaggtg gcatcactgcaagatatgtcctgccaactgctagtcaatgctgaaggcaaagactgcctt gaagccaaagaaaaggtgcatgtcattggaaatagactgaagctcctcttgaaagaggtc acacgtcatattaaagacctagagaaaattctagacatttcgagtaatcaactggaattg tcctcatggtcctctgctgatgaattagacacgtcaggctcagtgagtcctgtatctgga agaagcactccaagcagacagagaacgccacggggcaaatgtagtctctcacagcctgga ccctctgtcagcagtccacatagcaggtccacaagaggtggctcaggttcctccccttct gaggccaggccagcatggcatcgcctgtccttcttcctcagagtcctcagagctgctctg ccacttcagctcctcttactgctcctgattgggctggcatgcctggtgccaatgactgag gaggactacagctgtactatggctaacaactttgcccgctctttccaccccatgctaaaa tacatgaatggtccacctccgttatga

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