KEGG   Cheilinus undulatus (humphead wrasse): 121528226
Entry
121528226         CDS       T07473                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
cud  Cheilinus undulatus (humphead wrasse)
Pathway
cud04010  MAPK signaling pathway
cud04012  ErbB signaling pathway
cud04020  Calcium signaling pathway
cud04510  Focal adhesion
cud04520  Adherens junction
cud04530  Tight junction
Brite
KEGG Orthology (KO) [BR:cud00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121528226 (erbb2)
   04012 ErbB signaling pathway
    121528226 (erbb2)
   04020 Calcium signaling pathway
    121528226 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    121528226 (erbb2)
   04520 Adherens junction
    121528226 (erbb2)
   04530 Tight junction
    121528226 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cud01001]
    121528226 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cud04147]
    121528226 (erbb2)
   04090 CD molecules [BR:cud04090]
    121528226 (erbb2)
Enzymes [BR:cud01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     121528226 (erbb2)
Protein kinases [BR:cud01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   121528226 (erbb2)
Exosome [BR:cud04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   121528226 (erbb2)
CD molecules [BR:cud04090]
 Proteins
  121528226 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Tcell_CD4_C
Other DBs
NCBI-GeneID: 121528226
NCBI-ProteinID: XP_041671476
LinkDB
Position
20:19419581..19457775
AA seq 1303 aa
MEAVRSLLFVGAVLLGVTGALGREVCLGTDMKLALPSSQENHYETLRLLYTGCQVVHGNL
EITHLHGNPDLSFLQGIVEVQGYVLVAHVSVSLVPLDNLRIIRGSQLYNSSYALAVLDNT
LNGQGLRTLRLRSLTEILLGGVYIWGNPQLCFPDAQNIIWRDTLDEQNSHARMQRLQPRA
PKCPSCASACGKSCWGETAQDCQTLTRIKCASGCQRCKGPLSNDCCHMQCAAGCTGPKDS
DCLACRHFNDSGVCKENCPPPTIYDPVTFQTKPNPNKKFNFGATCVKTCPYNYLAMEVAC
TLLCPKANQEVIIRSPDGNETQKCEKCEGDCPKVCYGLGMDNLGVTDNHGITMVTSSNVE
QFNRCKKIFGSLAFLPQSFARDPVTNRTGLTLEQLSAFRNLEEITGYLYVDAWPEDWGDL
SVFENLKVIRGRMLYKGVFSLAVQNLHIQSLGLRSLRSVSGGLVLLHNNSRLCYTDSIPW
DSLLHPTQGPHRIVSNNQKLQLCEAEGRVCHPLCEGGCWGPGPNQCVSCKTFQRGSECVE
QCDIFQGSVREYTDGSQCGVCHSECRPLNGSASCHGPGPDDCEECRNFQDGEFCVDHCPS
GIKEDQQTVWKYSNATGHCLPCNTNCTLSCTVMDDRGCPIDTRTGPGTTIAAAVGGVVLF
FILLALLVFYLRRQKKLKRKETMRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLR
VLGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVFSPYVCR
LLGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQFLLNWCVQIAKGMSYLEEVRLVHR
DLAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRRFTHQSD
VWSYGVTVWELMTFGAKPYDMIPAREIPDVLEGGERLPQPLICTIDVYMIMVKCWMIDPD
SRPKFKDLVNDFSAMARDPSRFVVIQNDEQMSMSSPVDSQFFRMLLEEEGNNMRELLDAE
EYLVPQPNLFPRTQTDGLQTNGPSRHQSYKQSRDQGLDIDPSIASGPRSMYSSLSTLGRS
QYPTLPLGASTSNGLWTPQYPTLNRSPSAGGQSDSVFLDGPADDPSIPPASPGRYSKDPT
NGSQGDLEMDGPVQNGFHLPNHLHHSLPRRSQGYIHNQALPEYVNQEIQDFRPIIPERPT
TLPRKGSRVDRRLPNGLSSGHSVENPGYLVPAKSGASTSPAFDNPYYLDLVAKAQAIAGA
AVVDGPEALERDRGLPSHVNGFVTPTAENPEYLGLADTWSGYT
NT seq 3912 nt   +upstreamnt  +downstreamnt
atggaggcggtgagaagtttgctgtttgtcggggccgtgctgctcggagtgacgggcgca
ttgggcagagaagtatgcctgggtacagacatgaagctagctcttccctccagccaggaa
aatcactatgagaccctgaggttgctctacactggctgtcaggttgtccacggaaacctg
gagattacacaccttcatggaaaccctgacctctccttcctacaggggattgtggaggtt
cagggctatgtgcttgtagctcatgtgtcagtaagtctagttcctttggacaacctcagg
atcataagaggcagccagctatacaactccagctacgctctggctgttctggacaacaca
ctgaatggacagggactcaggactctccggctacgaagcctcacagagatcctgttgggt
ggagtgtatatttgggggaaccctcagctgtgctttccagatgcccagaatattatttgg
agggacactttggatgagcaaaacagccacgcgaggatgcagcgactgcagcctcgagcc
ccaaaatgtccaagttgtgcctctgcatgtgggaaaagctgctggggagaaaccgctcag
gactgccagactttgacccgtattaaatgtgcgtctgggtgtcagaggtgtaaaggtccc
ctttcaaacgactgttgtcacatgcagtgtgctgccggctgcactggacccaaagactct
gactgtctggcttgccgtcatttcaatgacagtggtgtgtgtaaagaaaactgcccccca
ccaactatctacgaccctgtcacctttcagaccaaaccaaacccaaacaagaagttcaac
tttggagccacctgtgtgaagacttgtccctataactatctggccatggaagtggcctgt
accttgctttgtccgaaagctaaccaggaagtcatcatcaggagccctgatggaaacgag
acgcagaaatgtgagaagtgtgaaggagactgtcctaaagtgtgttatgggttgggtatg
gacaacctaggtgtcacagacaaccatggcatcaccatggtaacatcatctaatgtggag
cagttcaaccggtgtaagaagatatttggtagtttggccttcctccctcagagctttgca
agggaccctgtaactaacaggaccggcctgaccctcgagcagctgagtgcctttagaaat
ctggaggagattacaggatatctgtatgttgatgcctggccagaagactggggtgacctg
agtgtgtttgagaacctgaaggtgatcagaggcaggatgctctacaagggggtcttttca
ctcgcagtccaaaatcttcacatccagtctctggggttgcgatccttgcgtagtgtcagc
ggaggcttagtcctgttgcacaacaattcccgcctctgttacactgattcaattccctgg
gacagtcttctccatcccacccaggggccccaccgtattgtcagcaataaccagaaactc
caactctgtgaggcagaggggcgtgtttgtcatccgctgtgtgaggggggctgctggggt
cctgggcccaaccagtgtgtgtcctgcaagacttttcagcgtggttctgagtgtgtcgag
cagtgtgacatctttcagggttctgtgcgtgaatacacggatggatctcagtgcggcgtc
tgtcactcagagtgtcgacctctgaatgggtctgcctcctgtcacggaccgggtccagat
gattgtgaagagtgcagaaacttccaggatggtgaattttgtgttgaccattgtcccagc
ggcatcaaagaggatcagcaaacggtgtggaagtacagcaatgcaactggacactgtctg
ccctgcaacaccaattgcacgctgtcctgcactgtgatggacgatcgaggctgccccatt
gacaccaggacaggcccgggcacaaccattgctgctgctgtgggtggtgtagtgctgttc
ttcatcctgctggccctgctggtcttctacctgaggaggcagaagaagctgaagaggaag
gagacgatgaggaggatccttcaggaacatgagctggtggagcctttaacacccagtggt
gcgtcacccaatcaagctcagatgcgtatcctgaaggagactgagctgaaaaagctccgg
gtgttgggtgcaggggcctttggtaccgtttacaagggagtttgggctcctgatggggaa
aatgtcaagataccagtcgccataaaggtgttgcgagagaacacatcaccaaaagccaat
aaagagatccttgatgaggcctatgtgatggccggggtgttcagcccctacgtgtgtcgt
ctgttggggatttgtctgacctccacagtgcagctggtcactcagctgatgccttacggc
tgcctcctcgactacgtcagagagaacaaggatcgcataggttcccagttcctcctcaac
tggtgtgtccagatagcaaaggggatgagttatctggaggaagttcggctcgtccacaga
gatttggcagctcgtaacgttctggttaaaaacccgaatcacgtgaagatcactgacttc
ggcctggcccgtttgcttgatatagacgagactgaatatcacgctgacggaggaaaggtg
ccgattaaatggatggccctggagtccattctgcacaggaggttcacacatcagagcgac
gtctggagttatggggtgacagtttgggaactgatgacgtttggtgcaaaaccttatgac
atgatccctgcaagagaaatccctgatgttttagagggaggagaacggcttccacaaccc
cttatctgcaccatcgatgtctatatgatcatggtcaaatgctggatgattgacccagac
agcaggcccaagttcaaagatctggtgaatgatttcagcgccatggccagagatccgtct
cgttttgttgtcatccagaacgacgagcagatgagcatgtcgagcccagtggacagccag
ttcttccggatgcttctggaggaggaagggaacaatatgagggaactgctggatgcagag
gagtatctggtgcctcagcccaacctctttcccaggactcaaacagacgggcttcaaacc
aacgggccatccagacaccagtcatacaagcagagcagagatcagggcttggatattgat
ccctccatcgccagcggtcctcggagcatgtattcatcactgagcactttgggtcgcagc
cagtacccgactttacctttaggagccagcacctctaatggcctgtggactcctcagtac
ccaactctgaatcgcagcccctctgctgggggccagtctgactctgttttcctggacgga
cctgcagacgacccctccatccccccggccagcccgggacgctacagcaaagaccccacc
aacggaagtcagggtgacctggagatggatggaccagtgcaaaatggctttcatcttcca
aatcaccttcatcactccctgcccaggcgaagtcaggggtatattcataatcaagctttg
ccagaatacgtaaaccaggagattcaggattttaggccgataatccctgagcggcccacc
acgctgcctcgtaaaggctccagagtagaccgccgcctccctaacggcctgagctctggt
cacagcgttgaaaacccaggatacttggttcctgcaaagtctggggcctctacttctcca
gcgtttgacaacccatactacctggacctcgtggctaaagcgcaagccattgccggggct
gctgtggtggatggccctgaggcgctggagagagacagaggacttcccagccatgtgaat
ggatttgttactcccacagcagagaatccagaatatctgggattagctgacacttggagt
ggatacacctga

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