Cupriavidus sp. EM10: KLP38_07075
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Entry
KLP38_07075 CDS
T10452
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cupe Cupriavidus sp. EM10
Pathway
cupe00230
Purine metabolism
cupe01100
Metabolic pathways
cupe01110
Biosynthesis of secondary metabolites
Module
cupe_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
Enzymes [BR:
cupe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
KLP38_07075 (purL)
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NCBI-ProteinID:
QWE95598
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Position
1:1467468..1471514
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AA seq
1348 aa
AA seq
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MAHFSCFPGALALSAFRQQRLLAALQQVDADIESVHGQFVHFVDSDTPLSTEDQTRIGAM
LTYGAPFTAQPEGDRFVVIPRFGTISPWASKATDIAHNCGLTHVHRIERGIEITVVCKKG
LLRGRKTLDAGTRAAVAAHLFDRMTETVIASREEAAGLFQELPAKPLQFIDISAGRSALV
DANTAMGLALSEDEIDYLLENYGKLGRNPTDVELMMFAQANSEHCRHKIFNATWTIDGVA
QDKSLFAMIRNTHQLNPQGSIVAYSDNSAVMEGDVAERWYPRGADQKYGRHEALTHTLMK
VETHNHPTAISPFPGASTGAGGEIRDEGATGRGAKPKAGLTGFTVSNLMLPGAVEGWENA
RDAAQPLAHRNPDDKPGVTGKPDRIASPLQIMIDGPLGGAAFNNEFGRAALGGYFRVYEQ
NVGGTVRGYHKPIMIAGGIGNIDAGHTHKNPLPAGTLLIQLGGPGMRIGMGGGAASSMAT
GTNTADLDFDSVQRGNPEMERRAQEVINACWQLGEDNPILSIHDVGAGGISNAFPELVDG
ADRGARFELRQVHLEESGLSPAEIWCNESQERYVLAIAPNDLPRFQAMCERERSPFAVVG
IATEEKQLQLVDANVDAALKEHFTVDMPMDVLLGKPPRMHRDVQRVQRELPPVDVTGISL
EQAVSDVLRHPTVASKSFLITIGDRTVGGMNARDQMVGPWQVPVADVAVTTLDYKGRAGE
AMTMGERTPLAVIDAPASGRMAIGEALTNLAAAPVKDLNKVKLSANWMAACGVAGEDAKL
YDTVHAVGMELCPALGISIPVGKDSLSMRTKWSDADGDKEVVAPVSLIISAFAAVDDTNK
TLTPQLRTDLGDSTLIAIDLGRAKNRMGGSILAQVTQQVGDRAPDVDSPEDLKNFFNVIQ
RLNREGKLLAYHDRSDGGFMATVAEMAFAGHTGVSLNVDMLTLDPTQEQDYGDAKNWAQQ
VAELRNDRTLRALFSEELGAVIQVRAEERDAVFAVLREAGLSACSHVIGKPNTSDQIEIY
RDAKKVFGAARADLQRTWTEVSWRIARLRDNPACADSEYDRVLDAADPGISPVLTFDPAH
DIAAPFIATGNRPRVAILREQGVNSQIEMAYSMDLAGFETVDVHMSDLIAGRATLADFKG
FVACGGFSYGDVLGAGEGWAKTILFNGQMAEQFAAFFNRQDTFALGVCNGCQMLSNLAPI
IPGAGAWPKFTRNLSEQYEARFVTVEVQQSPSIFFAGMEGSRIPIAVAHGEGFADFSQQG
DIAKVDVALRFVDNRGAVTQTYPLNPNGSPQGITSVTTSDGRFTALMPHPERVFRAATMS
WAPDAWKDVADGGSPWMRMFRNARKWVG
NT seq
4047 nt
NT seq
+upstream
nt +downstream
nt
atggcgcatttctcgtgcttccccggcgctttggcgctttccgctttccgtcagcaacgc
ctgcttgccgccctgcaacaagtcgacgccgatattgagtccgtccatggccaattcgtg
catttcgtcgattcggacaccccgttgtccaccgaggatcagacgcgcattggcgcgatg
ctgacctatggcgcgccgtttacggcccagcccgagggcgaccgtttcgtggtgattccg
cgtttcggcaccatttcgccctgggccagcaaggccaccgacatcgcccataactgcggc
ctgacgcacgtgcatcgcatcgagcgcggcatcgagatcaccgtggtctgcaagaagggg
ctgctgcgcggccgcaagacgctggacgccggcacccgcgccgccgtggccgcgcacctg
ttcgatcgcatgaccgagaccgtgatcgcttcgcgcgaggaagcggccggcctgttccag
gaactgccggccaagccgctgcagttcatcgacatttcggcgggccgcagcgccctggtt
gacgccaacacggcgatgggcctggcgctgtcggaagacgaaatcgactacctgctggag
aactacggcaagctcggccgcaatccgaccgatgtcgagctgatgatgttcgcgcaggcc
aacagcgaacactgccgccacaagatcttcaacgccacctggaccatcgacggcgtggcg
caggacaagtcgctgttcgcgatgatccgcaacacgcaccagttgaacccgcagggatcg
atcgtggcctattcggacaactcggccgtgatggaaggcgatgtggccgagcgctggtac
ccgcgcggcgcggaccagaagtacggtcgccacgaggccctgacccatacgctgatgaag
gtggagacgcacaaccacccgaccgcgatctcgccgttcccgggcgcctccaccggcgcc
ggcggtgaaatccgggacgaaggcgctacgggccgcggtgccaagcccaaggccggcctg
accggcttcacggtgtcgaacctgatgctgcccggtgccgtcgagggctgggaaaacgcc
cgcgatgccgcgcagccgctggcgcaccgcaatcccgacgacaaacctggcgtcaccggc
aagccggaccgcatcgcatcgccgctgcagatcatgatcgacggcccgctgggcggcgcc
gcgttcaacaacgaattcggccgcgccgctctgggcggctacttccgcgtctacgagcag
aacgtgggcggcacggtgcgcggctatcacaagccgatcatgattgccggcggcatcggc
aatatcgacgccggccacacgcacaagaacccgctgccggccggcacgctgctgatccag
ctgggcggcccgggcatgcgcatcggtatgggcggcggcgccgccagctcgatggcgacc
ggcaccaacacggccgacctggacttcgactcggtgcagcgtggcaaccccgaaatggag
cgccgtgcccaggaagtgatcaacgcctgctggcaactgggcgaagacaacccgattctg
tcgatccatgatgtcggcgcgggtggtatttcgaatgccttccccgaactggtcgacggc
gccgatcgcggcgcccgtttcgagctgcgccaggtgcatctggaagagtcgggcctgtcg
ccggccgaaatctggtgcaacgagtcgcaggagcgctacgttcttgccatcgccccgaac
gacctgccgcgcttccaggccatgtgcgagcgcgagcgctcgccgttcgccgtggtcggt
atcgccaccgaggaaaagcagctgcagctggtggacgccaatgtggacgccgcgctgaag
gagcacttcacggtagacatgccgatggacgtgctgctgggcaagccgccgcgcatgcac
cgcgacgtgcagcgggtgcagcgcgaactgccgccggtggacgtgaccgggatctcgctg
gaacaggccgtgagcgacgtgctgcgtcacccgaccgtcgcgagcaagtcgttcctgatc
acgatcggcgaccgtaccgtcggcggcatgaacgcacgcgaccagatggttggcccgtgg
caggtgcccgtggcagatgtggccgtgaccacgctcgactacaagggccgcgccggcgaa
gcaatgacgatgggcgagcgcacgccgctggccgtcatcgacgccccggcttcggggcgc
atggccattggcgaggcgctgaccaacctggcagccgctccggtcaaggatctgaacaag
gtcaagctgtcggccaactggatggccgcctgcggcgtggccggcgaggatgccaaactg
tacgacaccgtgcatgccgtcggcatggaactgtgcccggcgcttggcatcagcatcccg
gtgggcaaggattcgctgtcgatgcgcacgaagtggtcggatgccgatggcgacaaggaa
gtggtcgccccggtctcgctgatcatttccgctttcgcggccgtggatgacaccaacaag
accttgacgccccagttgcgcaccgatctgggcgacagcacgctgatcgccatcgacctg
ggtcgtgcgaagaaccgcatgggcggcagcatcctggcgcaggtgacgcagcaggtgggc
gatcgcgcgccggatgtggacagcccggaagacctgaagaatttcttcaacgtgatccag
cgcctcaaccgtgaaggcaagctgctggcctatcacgaccgttccgacggcggtttcatg
gccaccgtggcggaaatggctttcgccggccatactggcgtgtcgctcaacgtggacatg
ctgacgctggatccgacccaggagcaggactacggcgacgccaagaactgggcgcagcag
gttgccgagctccgcaacgaccggacgctgcgcgcgctgttctcggaagaactgggcgcc
gtcatccaggtccgtgcggaagagcgcgatgccgttttcgcggtgctgcgcgaggccggg
ctgtcggcttgcagccatgtcattggcaagccgaacacgagcgaccagatcgagatctac
cgcgacgccaagaaggtcttcggcgccgcccgtgccgacctgcagcgcacgtggaccgag
gtgagctggcgcatcgcgcgcctgcgcgacaacccggcctgcgcggacagcgagtacgac
cgcgtgctggacgccgccgatccgggcatcagccccgtgctgaccttcgatccggcgcac
gatatcgccgcaccgttcattgccacgggcaaccgtccgcgcgtggcaatcctgcgcgag
cagggcgtgaactcgcagatcgagatggcctacagcatggacctggccggcttcgagacg
gttgacgtgcatatgagcgatctgatcgccggccgtgccacgctggccgatttcaagggt
ttcgtggcctgcggcggcttcagctacggcgacgtgctcggcgcgggcgagggctgggcg
aagacgatcctgttcaacggccagatggcagagcagttcgcggcgttcttcaaccgccag
gacacgttcgcgcttggcgtgtgcaacggctgccagatgctgagcaacctggcccctatc
atcccgggtgccggtgcatggccgaagttcacgcgtaacctgtcggagcagtacgaagcg
cgcttcgttaccgtggaagtccagcagtcgccgtcgattttctttgccggcatggaaggc
agccgcatccccatcgccgtggcgcatggcgagggtttcgccgacttctcgcagcaaggc
gatatcgcgaaggtggacgtggcgctgcgcttcgtcgacaaccgcggtgccgtgacgcag
acgtacccgctgaacccgaacggatcgccgcagggcatcacgtcggtgacgacctccgat
ggccgcttcaccgcgctgatgccgcacccggaacgcgtgttccgcgccgcgacgatgagc
tgggcgccggacgcctggaaggacgtcgccgacggcggtagcccgtggatgcgcatgttc
cgcaacgcccgcaagtgggtgggctga
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