Corynebacterium ureicelerivorans: CUREI_01085
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Entry
CUREI_01085 CDS
T03241
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cuv
Corynebacterium ureicelerivorans
Pathway
cuv00860
Porphyrin metabolism
cuv01100
Metabolic pathways
cuv01110
Biosynthesis of secondary metabolites
cuv01120
Microbial metabolism in diverse environments
cuv01240
Biosynthesis of cofactors
Module
cuv_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cuv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CUREI_01085
Enzymes [BR:
cuv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CUREI_01085
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CUREI_01085
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AIL96096
UniProt:
A0A077HI60
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Position
207440..209191
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AA seq
583 aa
AA seq
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MTEPTHAPQPGKVIFVGAGPGNPELLTVRAREVMESNSIALVDPEVSTGVRSVVAAALPV
PQAKVDEANARYEQMCAEAKEAGARRKPPRPEAPTAAEIEVVGLEGDAIVEKLKRALKDA
ADALERGEAGDGDVIRVVCGNPLTRDSVMEEISAVAAAGMEFQVVPGMSLPSTVPSFAGI
ALGSTYTETDLNNGPVNWDQLASAPQPLVFQANQEHLAEMVEQLTQRGFQGATPVTVTTR
GTTRLQRTFDATLETMGKLDADLEGPLVVTLGTAADDRSKYSWWENRPLYGWRVLVPRAK
EQAGPMNARLSQHGAIPQSVPTISLEPPRNPAQMDRAIKGIVEGRYQWVLFTSVNAVNAV
WGKFEELGLDARSFAGVHLGAVGQKTAGALRDRGMQAELVPHRTKQNAAGLAEAFPEYVE
DIDPVSRVLLPRADLGSDVLVDGLKEKGWEVDDVVAYRTVRAAPPPPETRDMIKTGGFDA
VCFTSPSTVKNLVGIAGKPHPRTIIACIGPVTEAEAREQGLRVDVVPEVADIPNLVDALA
DHVAGLRAAGQLPPPRKKRRKTAPAATGAKADDADGDAPSADN
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgacagagcccacgcacgccccccagccggggaaggtgatcttcgttggcgctggaccg
ggcaacccagagttgcttactgtccgcgctcgcgaggtaatggaatccaactctatcgcc
ctcgtggatccggaggtgtcaacgggggtccgaagtgtcgtcgcggcggcgctgccagtg
ccgcaagccaaggtagatgaggccaacgcgcgctacgagcagatgtgcgccgaggcgaaa
gaagctggcgcgaggcgtaaaccgccgcgtcccgaagccccgacggcagcggagatcgag
gttgtggggttggagggcgacgcgatcgtcgagaagctgaagcgggcgttgaaggatgcg
gcggatgcgctggagcgcggtgaggctggcgacggcgacgtgatccgcgtcgtgtgcggt
aacccgctgacgcgcgattcggtgatggaggagatctccgcggtcgctgcggccgggatg
gagttccaggtggtgccggggatgtcgctgccctcgacggtgccctcctttgccggcatc
gcgctcggctccacatacaccgagacggacctgaacaacggcccggtgaactgggaccag
ctggccagcgccccgcagccgctggtgttccaggccaaccaggagcacttggcggagatg
gtggagcagctcacgcagcgcggattccagggcgccacgccggtgaccgtgaccacgcgc
ggaaccacgcgtctgcagcgcacgttcgacgccacgctggagaccatgggcaagctcgac
gcggacctggaaggcccgcttgtggtcacgctgggcaccgccgccgacgaccgttccaag
tactcgtggtgggagaaccgcccgctgtacggctggcgcgtccttgtgccgcgcgcgaag
gagcaggctggtccgatgaacgcccgcttgtcccagcacggcgcgatcccgcagtcggtg
cccacgatctcgctggagccgccgcgcaacccggcgcagatggaccgcgcgattaagggc
atcgtggagggccgctaccagtgggtcttgttcacctcggtaaacgcggtgaacgcggtg
tggggcaagtttgaagagctgggtttggacgcgcgctcgttcgcaggcgtgcacttgggc
gcagtggggcagaagactgccggcgccctgcgcgaccgcggcatgcaggccgagctggtg
ccgcaccgcaccaagcaaaacgccgccgggctggcggaggcattccccgagtacgtcgag
gacatcgaccccgtctcgcgcgtgctccttccgcgggcggacctgggctccgacgtgctg
gtggacggcctgaaggagaagggctgggaagtcgacgacgtggtggcctaccgcaccgtg
cgcgccgccccgccgccgccggagacgcgcgacatgatcaagaccggcggcttcgacgcg
gtgtgcttcacctctccgtcgacggtgaagaacctcgtgggcatcgcgggcaagccgcac
ccgcgcacgatcatcgcctgcatcggcccggttacggaggcggaggcgcgtgagcagggg
ctgcgtgtcgacgtcgttccggaagtcgccgacatccccaacttagtggacgcgttggcg
gaccacgtggcgggtttgcgagcggctgggcagctgccgccgccgcgcaagaagcgccgc
aaaactgcccctgcggccacgggtgcgaaggcagacgacgcggatggggatgcgccgtcg
gccgacaactga
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