Corynebacterium variabile: CVAR_1158
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Entry
CVAR_1158 CDS
T01594
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cva
Corynebacterium variabile
Pathway
cva00300
Lysine biosynthesis
cva00550
Peptidoglycan biosynthesis
cva01100
Metabolic pathways
cva01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cva00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CVAR_1158
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CVAR_1158
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CVAR_1158
Enzymes [BR:
cva01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CVAR_1158
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEK36514
UniProt:
G0HEC2
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All DBs
Position
1334086..1335528
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AA seq
480 aa
AA seq
DB search
MVTGPVEFDSRRVTAGSVYMALPGARVDGHDFVGPALEAGAALVMAGRPTALPELLCPAV
EEEQGTQRNASYLDNDPDGLGERVITAVSRLARHSTEVLVAENRLTVIGVTGSAGKTSTK
DLLGAVFSRDGETIAPPGSLNNEIGHPYTVLKAGRTTKYLVAEMSARGQGHIAHLARIAP
PRIGVVLNVGTAHLGEFGSREGIAQAKGELVEALPPAAEGGVAVLNADDDLVSGMAPRTA
ARVVYYSADQGADGTADYRASDITLDEVARASFLLHHPEGEPVKVSLGVFGAHNVANALA
AAAAAIECGLAPSEVASALTGYTAASANRMDVRTRPDGLTVINDSYNANPDSMRAGIDAL
AHAASTRTGTESWAVLGQMAELGEDAVGEHTGIGAYLAERGIDRLIVVGHGVNQDALAAA
GEDNGIRTRQVDDVDGAVNLLTGAPTHPGDVVLVKASYSDGLWRVAERLHAAVSNSSQAR
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
gtggtgaccggaccggtggagttcgactcccgccgcgtcaccgccggcagtgtctacatg
gctctgcccggcgcccgtgtcgacgggcacgacttcgtcggccccgccctggaagcaggg
gcggcccttgtcatggccggccggcccaccgcactgcccgaactgctctgcccggcggtc
gaggaagagcaggggacgcagcgtaacgcgtcctacctcgacaacgaccccgacgggctg
ggagagcgggtcatcaccgcggtgtcccggctcgcccgacacagcaccgaggtgctcgtc
gcggagaaccgtctgaccgtcatcggggtcaccggctcagccggcaagacctcgaccaag
gacctgctcggtgcggtgttctcccgcgacggcgagaccatcgccccgcccggcagcctc
aacaacgagatcggtcacccgtacaccgtgctcaaggccggtcggacgacgaagtacctc
gtcgccgagatgtcggcccgtggacagggacacatcgcccacctggcacgtatcgccccg
ccgcggatcggtgtggtcctcaacgtcggtaccgcccacctcggcgagttcggttcccgc
gagggcatcgcgcaggccaagggtgaactggtcgaggctctgcccccggccgccgagggt
ggcgtggcggtgctcaacgccgacgacgacctggtctccgggatggcgccgcgcactgca
gcgcgggtcgtgtactactcggccgaccagggcgcggacggcaccgccgactaccgggcc
tcggacatcaccctcgacgaggtcgcccgggcgtccttcctcctgcaccacccggagggt
gagccggtgaaggtcagcctcggcgtcttcggcgcgcacaatgtcgccaacgccctcgct
gccgcggcggccgccatcgagtgcggtctggccccgtcggaggtggcgtcggcactcacc
gggtacaccgccgccagcgccaaccgcatggacgtccggacccgtcccgacggtctcacc
gtgatcaacgactcctacaacgccaacccggattcgatgcgggccgggatcgacgccctg
gcacacgccgcgtcgacccggaccggcacggagtcctgggccgtcctcggccagatggcg
gagcttggggaggacgccgtcggcgaacacaccggcatcggtgcctaccttgctgagcgg
ggtatcgaccggctcatcgtcgtcggacacggcgtcaaccaggatgccctggccgccgcc
ggcgaggacaacgggatccggacccggcaggtcgacgatgtcgacggcgcagtgaacctg
ctcaccggcgcgcccacccaccccggcgacgtcgtgctcgtcaaggcgtcttattctgac
gggctgtggcgcgtggccgaacgcctccacgccgctgtctccaattcctcccaggcaagg
taa
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