Synechococcus sp. JA-3-3Ab: CYA_0077
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Entry
CYA_0077 CDS
T00318
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
cya
Synechococcus sp. JA-3-3Ab
Pathway
cya00300
Lysine biosynthesis
cya00550
Peptidoglycan biosynthesis
cya01100
Metabolic pathways
cya01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
cya00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CYA_0077 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CYA_0077 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CYA_0077 (murF)
Enzymes [BR:
cya01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CYA_0077 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SHPRH_helical-1st
Motif
Other DBs
NCBI-ProteinID:
ABC98307
UniProt:
Q2JY10
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Position
75903..77240
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AA seq
445 aa
AA seq
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MLTLQTVADLLQAPLQGDPHLLGLPVQALCTDSRRLQPGSVFVALRGERFDGHDFIPQAL
SKGAVAVISQRPVEGPHFQVPDTLTAYQRIARAWREQFSIPVVAITGSAGKTTTKEMLAA
ALSRYGSVLKSEANHNNDIGVAQTLLRLQPEHQFAVLEMAMRGPGEIRRLAQMARPTHAL
ITHIGTAHIGRLGSREAIAAAKCELLQELGQGIAVLNGEDPLLLATAASLWSGKTLTYGL
AQGDLRGEWDPQAQTVTVEGLTLPVPLPGRHHALNWMGVLAAVRSLGLNWERLQEPLDLP
LPLEGRNRHLKLAGDVEIWDETYNASPEAMIAALHLLAQTAGKRRWAILGPMRELGEHAP
QLYAEVGRAAASLRLERVWLLDPDGEMQPLVDEKPAAEVERFEEASALVEGLQQQVRAGD
RLLFKAARAVELERVLHRFLQAWQG
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
atgctgaccttgcaaactgtggccgacctgctgcaagcccctttgcagggagatccccac
ctcttggggttgccggttcaggccctctgcaccgacagccgccggttgcagccaggatcc
gtttttgtggcgctgcggggagaacgcttcgacgggcacgattttattccgcaagccctg
agcaagggggccgttgctgtcatcagccagcggccggtggagggtccccacttccaggtt
cccgataccttgactgcctatcagcgcattgccagagcctggcgggagcaattttccatc
ccggtagtggccatcaccggctcagcaggcaaaaccaccaccaaggaaatgctggcggct
gctctttcgcgctacggcagcgttctcaaaagcgaggccaaccacaacaacgacattggg
gtggcgcaaacgctgctgcggctacaaccagaacaccagtttgccgttctggagatggcc
atgcgcggccctggtgagattcgccgccttgcacagatggctcgccccacccatgccttg
attacccacatcggcaccgcccacatcggcaggctgggatcccgcgaggccattgctgct
gccaagtgtgagctgctgcaggagttggggcaggggatagctgtgctcaatggtgaggat
cccttgctgttggccactgccgccagcctgtggtcgggaaaaaccctcacctatggcctc
gcccaaggggacttgcgaggagaatgggatccccaagcccaaaccgtaaccgtggagggc
ttgaccttgccggtgcccctgccaggaaggcatcacgcccttaactggatgggggtgctg
gcggctgtgcgcagcttgggtctgaattgggagcgcctgcaagagccccttgacctaccg
ctgcctctggaggggcgcaatcgccatctcaagctggctggggacgtggagatttgggat
gagacctacaacgcctcgccggaagcgatgatcgcggctttgcacctgctggctcagact
gcgggaaaacggcgctgggccatcctcggcccaatgcgggaactgggagagcatgcccca
cagctctacgcagaggtgggtcgggcggctgcctccttgagactggagcgggtctggctt
ttggatcccgacggggagatgcagccactggttgacgaaaagccagccgccgaggttgaa
cgctttgaggaagcttctgccttagtggagggtttgcagcagcaggtgcgggcaggggat
cgactgctgtttaaggcggcgcgagccgtcgagctggagcgggtgctgcaccgctttttg
caggcttggcagggataa
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