Dactylosporangium sp. AC04546: KZZ52_32080
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Entry
KZZ52_32080 CDS
T10220
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
dact Dactylosporangium sp. AC04546
Pathway
dact00280
Valine, leucine and isoleucine degradation
dact00640
Propanoate metabolism
dact00785
Lipoic acid metabolism
dact01100
Metabolic pathways
dact01110
Biosynthesis of secondary metabolites
dact01210
2-Oxocarboxylic acid metabolism
Module
dact_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
dact00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
KZZ52_32080
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
KZZ52_32080
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KZZ52_32080
Enzymes [BR:
dact01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
KZZ52_32080
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Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
WVK78630
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Position
complement(7068410..7070590)
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AA seq
726 aa
AA seq
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MESIDEHVVRRLTEWSSEAPTGTAEETEVDRAVLLDYWEAQVQARHLDLALRWLQAQKEG
FYTIGSSGHESNAAVALALRPSDPALLHYRSGGFYAARAGQVPGATPIADVLHSAAASRR
DPISGGRHKVFGHRALNIIPQTSTIASHLPRAMGLAFNLGRTAGTGPYPHDAVVVCSFGD
ASLNHSTAAGALNAVGYSAHQGLPIPLLLVCEDNGIGISTRSPHGWVRRALGSLPGIEYV
HADGTDPARLLAVAAAAARRVREERRPVVLHLGTVRFMGHAGSDAELAYRGRSEILADYA
RDPILATAAELARRGILSPAESLARYEHARKLVMDEARLLVGRVERLADPAAVTAPLTAR
RPEAVSAAAARAGAGREAVFGDRLPEARGPLTLAQSINAALHDALLARPGAQVFGEDVAR
KGGVYGVTRGLRKAFGGGRVFDTLLDEQSILGLALGGALAGTLPIPEIQYLAYLHNAEDQ
LRGEAASLRFFSAGQYQNGMVVRIAGLAYQKGFGGHFHNDNSVAVLRDIPGLALAVASHP
ATAPALLRQCLALAEQEGRVCVLLEPIALYHTRDLHAEGDGGWLAPYAAPSAWPEAPLGA
VRTVRDGGDLAIVTFGNGVPMSLRVAATLAAEGAETRVVDLQWLAPLPAQAMHAALDGVA
RVLVVDETRVSGGVSEAVVAALVDAGFAGRIARVNSVDSYVPLGPAADQVLLGEPDILEA
ARALLA
NT seq
2181 nt
NT seq
+upstream
nt +downstream
nt
gtggaatccatcgacgagcacgtcgtccgccggctcaccgaatggtcgtccgaagcgccc
accggcaccgccgaggagaccgaggtcgaccgggcagtcctgctggactactgggaggcc
caggtccaggcccgccacctggacctggcgctgcgctggctgcaggcccagaaggagggg
ttctacaccatcggctccagcggccacgagagcaacgccgccgtcgcgctggcgctgcgc
ccgagcgacccggcgctgctgcactaccgctcgggcgggttctacgccgcccgggccggc
caggtgcccggcgccaccccgatcgccgacgtgctgcactcggcggcggcgtcccggcgc
gacccgatctccggcggccggcacaaggtcttcgggcaccgtgccctgaacatcatcccg
cagacctcgacgatcgcgtcgcacctgccgcgcgcgatgggtctggccttcaacctgggc
cggacggccggcaccgggccgtacccgcacgacgcggtcgtggtgtgcagcttcggcgac
gcctcgctgaaccactccaccgcggccggcgcgctcaacgccgtcggctacagcgcccac
cagggcctgccgataccgctgctgctcgtctgcgaggacaacggcatcgggatcagcacc
cgctcgccgcacggctgggtgcgccgggcgctggggtcgctgcccggcatcgagtacgtc
cacgccgacggcaccgacccggcccgcctgctcgcggtcgccgccgccgccgcgcggcgg
gtccgcgaggagcgccggccggtcgtgctgcacctgggtaccgtgcggttcatgggccac
gccggctccgacgcggagctggcctaccgcggccggtcggagatcctcgccgactacgcc
cgcgacccgatcctggccacggcggcggaactggcccggcgcggcatcctgagcccggcc
gagagcctcgcccgctacgagcacgcccgcaagctcgtcatggacgaggcacgcctgctg
gtcggccgggtcgagcggctggccgacccggcggcggtgaccgcgccgctcaccgcccgc
cggccggaggcggtcagtgcggccgccgcgcgcgcgggagcgggccgcgaggccgtcttc
ggcgaccggctcccggaggcgcgcggcccgctcaccctcgcccagtcgatcaacgcggcg
ctgcacgacgcgctgctggcccggcccggcgcgcaggtgttcggcgaggacgtggcccgc
aagggcggcgtctacggcgtgacccgggggctgcgcaaggcgttcggcggcggccgggtc
ttcgacacgctgctggacgagcagtcgatcctcgggctggcgctcggcggcgccctggcc
gggaccctgcccatccccgagatccagtacctcgcgtacctgcacaacgccgaggaccag
ctgcgcggcgaggccgcgtcgctgcggttcttctcggccgggcagtaccagaacgggatg
gtcgtgcggatcgccggcctggcgtaccagaagggcttcggcggccacttccacaacgac
aactcggtcgcggtgctgcgcgacatccccggcctggccctcgcggtcgcgtcgcacccg
gcgaccgccccggccctgctgcgccagtgcctggccctggccgagcaggagggccgggtg
tgcgtcctgctggagccgatcgccctgtaccacacgcgcgacctgcacgccgagggcgac
ggcggctggctcgccccctacgcggcgccgtcggcgtggcccgaggccccgctcggcgcg
gtccgtaccgtccgcgacggcggcgacctggcgatcgtcaccttcggcaacggcgtgccg
atgagcctgcgggtcgccgcgacgctcgccgccgagggcgccgagacccgcgtggtcgac
ctgcagtggctcgcgccgctgccggcgcaggccatgcacgccgctctggacggggtcgcc
cgcgtgctcgtcgtcgacgagacccgggtgagcggcggggtctccgaggcggtcgtcgcg
gccctggtcgacgccggcttcgccggccggatcgcccgcgtcaacagcgtcgacagctac
gtgccgctcggcccggccgccgaccaggtgctgctcggcgagcccgacatcctggaggcg
gcccgcgcgctgcttgcctga
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