Danio aesculapii (panther danio): 130244242 Help Entry 130244242         CDS       T11734                                  Name (RefSeq) nesprin-1-like isoform X1   KO K19326   nesprin-1 Organism daes  Danio aesculapii (panther danio) Pathway daes04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:daes00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     130244242  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:daes03036]     130244242 Chromosome and associated proteins [BR:daes03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     130244242 SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 KASH Spectrin_SYNE1_2 SR_desmoplakin_3 ATG17_like SYNE3 Helical_needle BOS1_GOSR2_MEM11-like_N GAS Motif Other DBs NCBI-GeneID:  130244242 NCBI-ProteinID:  XP_056332548 LinkDB All DBs Position 17:45114170..45311363 Genome browser AA seq 6553 aa AA seqDB search MKQLCGGQDVPAKLQVMETDLRRKLNSIEELCDQAKNNLQDFCSQKKQLEDFLSQMSEWL MSVERSLVDSPCGTAPEEICRVKEIQKELQNQQASIDSARESLNTLCRKYPSEELAGLGS SLTDLIKKYETVNQICVKRLGSMQHGLQQHFNDLVKEFHTWLSGQKDIVRECADHSGDMS VVERKLQKLKGALERVDDGDDRLTLVCTEGEKLLLHLPKASAGQVQQSLSSIQQDWDSYV ELCRQNQQNLEDSASLLSGFDSRLQRLSRWLERMDVKMSTELPEGRHGDQERVTLERVEE FQHEVLKERDSFEGLCQEAQALSEGGHGSGSEVRASAQLQLQHQSLLKAARERLRVCQLS MQEQQNFQETLQSTWLWLSGAQERLTALNSTSGNKETLEKRLLLVQDILLMKGEGEVKLN MTVGKGEQVLKNCSRDKQEVIRSQLKSLKDSWANILMTAMSCHSRLEWTVAQWSSFQESK AQLQQWMEMVEQEAGVALPQQPGLKEKASLLERLRVIQADVEVHSTALSRLNEKATELYE KTGDQAFAEGPKSDFNTQFTNITAVIKSKVQQMEEIVKEHEQYMESVRDLNDWLTSAKEE LQRWSDMSGDAASVQRKLSKVRGLLDSRKQGRERLTRVQSCGAATRDHTSTVGCEVLERE EAGLLSAWEQWERGAKHVCSGLEGVLAQMANSEQEFNSLAAQLEQDLQEFSSKLQEWRIK LQQVEEMSAGDEAVQGWQIAKDTLEALLNVEPMSDNLKCQLNDLCRFSRDLGAQSERVSA LIKEYNSLSLQASRECQGKEKLLEQRFRAAFRDFQQWLVNAKINTAKCFDVPQNLAEASS SLQKIQEFLSDREQGQGKLNTVAASGELLMSIAAKDRVESVRAKINTAREDWKTLMTNLH QRENALQNLQAQMRDFETSVEPLQDWLNDTEEAVQESSSRLQDLTAKKQELHRLQSLLEE LASKEPQLLRLREKAQQLWDGHTAGKGFVHRVSQLSAQYLALSNLTKEKASRIERMVSEH QLFSQGLKELQNWVSDTSHMLQTYCTPTADKNVLDSRMIKLEALLTARQEKEIQLKMLLT RGESVQRNTSADGVPLVHQQIEDLKDSWDGLLSASIQCKSQLEGALSQWTSYQEDVRQFV TWMETVEETLSSADKQCSEMRDKTTNLGKAKLLLEDVLSHSSVLDVISMKGSNMAEHYVT QLEIQDLQERYNIVKDKAQCAVAKAEELVSAHQEYQHSLHEFKDWLEQQQERLSCYTQLE GDTEMLEDTLRKLQELQVHCTEGQALLNTLLVSREQVIPWGVPQLEDRCLEGVQQEWGSY QTRLTDTRSQLNSALAKLRQIEQKFQRLDNWLKGMESKGQLRTGRRSDRATKEAQLQLLK GWHEEVLVYQEEIEGLSVLAQQVLEETPISSRVSTRATQLTSRYHALLLHLLDTIKQLKE EVSCIEESQSVFSTFSEWLNTAQKNFSSVTTTNIDVVDRAAMEKKMKQLEALQGDMELGH TFLKTMREKTDRAMMFLEEPEAEQLKEEVDSRLSQLETLIRALRSEISATEKSIQLSKDF LDKFKTQTQWLSETKSLLASPVEPKAELYQKKAQLAKYKTIQQTIQSHESAVKSVIEKGD ALLETIRDPSISENISKLKTDYQDLCADAKARVQSLTESVREHEDYNSELQEVEKWLLQM SSRLVTSDSMQSGNLEMATQQLARHKAIMEEIAGFEERLSSLKDKGDRLVSSCTEQVQAK ISQQIQAHQQGTRDSYSAICSTAQRVYQSLDRELQKHVSHQDTLQQCQTWLSTVKEEIQM QPQTPYGLQEALKQVKHFRALQEQASTYLDLVCSVCDLSDESVRATAAKIQQTKTMIEER MSTSQELSDSWREIKEQKQELSTLFQDMEQQLQSLSRRPAELEPKIAQNMLDQAREIGQQ LQNRQSTLTKMTELVSKLTEGKESPEHTEIGRLSHAWLELCHQANILQTQREEDLKRTKE YHDCISAMEALFEQVSKEWDNLARTDAESSSDHLEALRKLSVVLKEKKSTLEDLKEQKQK VMYHLNLDDKELVKEQIGHFEQRWAHLESLIERKIQDSILTLEDMGQVEARLREAREWAE EQQPTLSEAMKMSPPPELAQSFLFDHLSICSELEAKQLLLAQAIGDADRVLAHLGLNERQ RLQQLISETQAEVECLSVKVAQRRKHLSKAFTERTQFLLAVNQAITWVQQNEKKAQAEEY IALLPDDLSKQVRTCRNIQSSLRAYQSELTSLWSQGRDLMKDAAEEEKTEMLRKLQELQS IFEVALQKCSQRLQELEKVLVTRKYFKADLEKICQWLKQADIVTFPEINLMNGDAELCSQ LTKYQQILDQAMEFENLLLTVQRTGQEILPTLNEVDHCYLDEKLIALPQQYNNILGLAKE KQEKIQQAILARQEYASFIDVTHKALKELEEQFHSLGTQPIGLKTEEVVNLQADYKALLE ELTNLGQAVGELNQKKEGFRSTGQPWMPEEMTQLVSLYNGLKRLIEQRVEHLDDTLESFE DHQAMAMQVDSELKATKEQLVKVNAETQSAEERLKNYHALAASLQGASSHLTRLMEQMDN LVSHMDTAAHEVSKQRVTSWQEELQSLQSSVGELIVECENRFVQSKDFETEVNRTLTWLQ QIKDELGSEVVVDVKVEKVQEEIRKQQIMQEEVQSRLRIVAALSTREKQKYTSANELVPA HVDSSLQEMAKLEADVQRALSSKQITLEQALVLCQKYHSRMQAACEWLEDAVGFLQQASL GVDVENYEECLRQQEDIMATEQEFLGVLEELESLPPQLENLVNPTAKEQLRLSVESAQQR GVEVRDQLQCHQDVLNSCVAQWNLYQEARQTVIELMNEVEKKLTEFSTAKAATNQEAEEK LRSHKSLVSMVNSFQEKLTGLEEQASQLEQIGSDASKATISRSMTTVWQRWTRLRSVARG QERVLEDTAHEWRTFREKMMKVRSLTEELKARVPDCTAEKASKATLQSHLDQYELVGQDL ERELSSLTLLRQYALSLIHDVEVSVPAADHEQLPSLKEIKAVQDQLESLLQKARAGKSRV QQELSDREGVERGLSLVKSWIQDSRELLLNPTSDLDILSQELEVMHGELITHRQNVDKLA EQQQSKYLDLYTILPSEISMQLAEVSLALGSIEDQVQARERDIQKSRVIKEEFNSRIHDV SEKMKAVSTALKEKATDIDQAKDEARRLCDELDGCGRTLAELEAAVQDFGRRNPLIARQL ADAIAKLREIHHHTLRLAEYKTIWLKKADAHLDEYNEMFEFIVKWTDRARSLVKANIIWN SSSHLQEQIRMYQAVLRESRELHGDLDSMQEKVEILSETLQVEAMGQQVSELSRHTEELE QSIRSRLQSLQDAAKDMEKFESEVKALHVSLDQVQATLTSPELARLSLKEQLTQRQRLLA DMESFKQQVETVQECQSALRVPEEVVTSLSICRTALNLQQEASQLQHTAIQQCNILQEAV VQYEQYEQEVKNLQVMIEDAHRVIQDQPVNTSNIQELQAQINHHEELAQKIKGYQEQIAS LNSKCKMLTVKAKHATTLLTVSEAEGLTESLEELDGELIQRKSQSQVSMSAGRCQSLLSP VTEESGEEGASEICSPAFCPSPSASTNTEAVISKMSMGRSSLTRAPVQELYNPALESVAS LDDLQRSWETLKNVISEKQKTLYEALEKQQRYQGSLQAISSKMESIETRLNEPPMHDLSP DRQMILHQNQMEEIVRLQDDIDELQSSFTEELYNPDAVDSDSADQLAMQSSLTVLADRMA TIHMKASGKRQILEERQSERVEKQQQAQALQHYLNQADQLDQWLKSTHGYIASCSQDSDA EEQLIDCQNMLLEMEEKVLALSELSRHSESLLLEGRPENREDAGQLARKLRTLKGSLLEL QRMLQDKQINLQATLIWEELKGPQRASDSLQEASDSSESDSTLSQSPNMQDWLAQARTTR SLQHQDTLQKQKELEEQLAEQKKLLKSVASRGEEILTQQASPVRASATETLSPDVELEGD SEAVKKQRRKRWESLKKDMATKLQLLMNTLEQDSKQPFYSRTACVKTAAPAPVYKRETHV QDKSNLMSLHNGFSQTIQEMTPQATEREVVLMEQQLYSAITATSSWVDDVENTLFSGPAL LTENADTQLSNHETLGKEVTEVTQEVGHSQGLIRGSVGLSEDEQSLMKDTLDCLTRRLGA LDSALDRRCESMRSRMRELSTFQTELQRLFTALSESKFQIIQKMAGVLDHTTTKQIETIA EVEDTLKDFEHRITELKARGAELQPDQFSTNELLKLQDAYEELVMTVGSRRSGINQNMAL KNQYERVLQDLIDLVDTAHDKMAADQKMIAGSVEDVHNLLDKHKEFFQGLEWHMVLTETF YKKISAFVLPRERQTLEETLARAQDVLKQAHKKGVELECVSETWSRLVLDYQTLYRLLEV VEGSLPSVGLVEETEERLNERIQLYQALRSSLTEHQHKLHQVLEEGKHLLSYVSCSSLEN QLTVLGEHWLNNTTKVNKELQNLQSMLKHLTRYKSESVELSRWLLEALERLEFWNTQFVA GPQELETVKGQLSAFLEFSKEVEARSSLKASVLNEGNQLLRLKKMDTASLRAELACLDSQ WSELLTRIPIVQEKLHQSQMDKLASRHAITELVNWISLMERVIEEDEENLKGAVGSKVIQ EYLQRYKGFRVDVNCKQLTVDFVNQSVLQISGADVESKRSDKTDFAEKLGAMNCHWQILQ TRITERVQYLEGLLVSWVEYEGKVQGLQAWLDAQEERLKRKHRIENLSSVQNALKDCQEM EVMVKEKERELERVEEQACALVQNKTDEACAVVMESLRALNNTWANLDHLIGQLKISLKS VQDKWNQYKQASEEINGYLTEGRYSVSRYRLLTGSLEASRLQVESLQNLQEELEKQESSM RKFGSVTLQLLEECHPSVSDTLNNTLKDINARWSSLQEEIVERLKSSKALLQLWQSYKDL YGQSDSSVQTLEEKANQMLKTASHKDITEEEVSAWIQDCAELLRSQAPVQASLQVLMELG EQLKQQVDTSAVASIQSDHLSLTQRLSVVEQSLSRQQVALQAGVRDYETFNEQLDSLSRW IVEAEEVLKGQDPNGSSDQSLIQDRMEDLKKQMLKFSSMAPDLERLNELGYRLPLNDSEI KRMQNLNRSWSTTSAQTTERFCKLQALLLQQQTFLEKCETWMEFLVQTEEKLAVEISGNF QSLMEQQRAHELFQAEMFSRQQILHSIISDGQHMLEQGQVDDRDEFKLKLALLSNQWQGV VRRAQQRRGIIDSLLRQWQRYREMVEKLRKWLLEVNHQTQSLQAGTPVPLQQARAMLDAV QLREKVLLRQQGSYILTVEAGRQLLLSADSRAEAALQEELLNIQERWRNANIRLDEQKKE LAVLLRDWERCEKGIGGSLEKLRAFKRQLSQPLPDRHEELQAEQMRCKDLESMFDGWKED LTHLTVLRESLSSYISLEDLRVLQERIELLHRQWEEICHQLSLRRQQVSEKMNEWAIFNN KYKELCEWLTQMESKVSHNGDISIEEMIEKLRKDYQEEVSAAQENKHELQHLGERLARAS HETKASDIEHKLSKVNERWQHLLDLIGARVKKLRETLVAVQQLDKNMNSLRSWLAHIETE LSRPIVYDTCDYQEIQRKLDLQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECD SIQQATRSLDRRWRSICAMSMERRLRIEETWRLWQKFLDDFSHFEEWLMLSEKTAALPNS SGVLYTIAKEELKKFETFQRHVHESLTQLELINKQYQRLARENRTDAACSLREMAHNANQ RWDNLQRRVSSVLRRLKHFISQREEFETARDCILVWLTEMDLQLTNIEHFSECDVQAKIK QLRAFQQEITLNTGKIDHIFQQGEALLEKSEPIDAAVIEEELEELQRYCQEVFGRVERYY KKLIRLPLTDDEHDISFSDREFDLDEGADVSSFPWSERLGDGFLSPLPSSSRSAPLRAER SGRDTPASVDSIPLEWDHDYDLSRGLESASRALSSSETGDQAEDDGYLQGSASALSDVVI PESPEAFLKLTEQTLRSSAGDAGSLETHIRQLDKALNTSCFHLQQTENIIRSRTPTGPEL DATYMGYMRLLEECRGSIDAVKRVGFELKDEDDKISGFVNPNSSESQTSGVIERWELLQA QALSKEMRMKQNMQQWQQFNSDLSSICSWLDQTEEELQQERGLDLGTDIHTIELRIKKLK ELQKALDKRKAIVLSINLCSAEFVQSDSEEAQDLQRRLKEMNNRWEKLSSSLDEWRTALQ HALMQCQDFHEMSHGLLLWLENIDRRRNEIIPIDHTQDSDTLQEHHKTLLQIRRELLDTQ VKVASLQDMSLQLLVHSEGSDCLEAKEKVHVIGNRLKLLLKGVTRDIRELQKTLDISSSQ QDLSSWSSADDLDTSGSLSPVSGRSTPSRQRPPRGKSSVSEPGACVSSPLHRSLNAAGSA SSPSEDEEPPSWCRSFLKRVFWAALPLQIILLLVLIVACLVPTAEDDYSCAQLNNFARSF HPMLSYTNGPPPI NT seq 19662 nt NT seq  +upstreamnt  +downstreamnt atgaagcagctctgtggtggacaagatgtccccgctaaactacaagtcatggagacggac ctcagaagaaaacttaacagcattgaagagttatgtgatcaagccaagaacaacctccag gatttctgcagtcagaagaagcagctggaggatttcctcagccagatgtctgagtggctg atgagcgttgagagatctttggtggattcaccctgtggaacggctcctgaagagatctgc agagtcaaggaaatccaaaaggagcttcagaaccagcaggcgagcattgattcagcccgg gaaagcttgaacacactttgcagaaaatacccatcagaggaactagctggtctaggatct tctctgacggatctcatcaagaaatatgaaacggtcaatcagatctgtgtgaaaaggctc gggtctatgcagcacggcctccagcagcacttcaatgatcttgttaaggagtttcatacg tggctctcaggacagaaagacattgtgagagaatgcgcagaccattcgggtgatatgagc gtggtggaacgcaaactgcagaaactgaagggagctctggagcgggtggatgatggagac gatcgtctaacactggtctgcacggagggagagaagcttcttctgcatctcccgaaagcc agcgccggccaggttcaacagagcctctcctccatccagcaggactgggacagttatgtg gagctgtgcagacagaaccagcagaacttggaggacagcgccagtctgctcagcgggttt gacagccgtctgcagagactgagccgctggctggagcgcatggatgtgaagatgagcaca gagctgccagaaggaagacacggcgatcaggagagagtcacgctggagcgggtggaagaa ttccagcatgaagtgcttaaagagagggactcgtttgagggtctgtgtcaggaggctcag gctctcagtgaaggaggtcacggcagcgggtcagaggtcagagcctccgcgcagctgcag ctccagcatcagtctctgctgaaggctgcgcgggaacggctgcgcgtctgtcagctcagc atgcaggagcagcagaacttccaggagacgctgcagagcacatggctgtggctgagcggc gcacaagagcggctcactgctctcaacagcaccagcgggaataaagagaccctggagaag agactgttgcttgttcaggacatcttgctgatgaagggtgaaggagaagtgaagctcaac atgacggtcgggaagggcgagcaggtgttgaagaactgcagtcgagataaacaggaagtg attcgttctcagctcaagagtctgaaggattcctgggcgaatatcctcatgactgccatg agttgccacagtcgtctggagtggactgttgctcaatggagcagttttcaggagagtaaa gcgcagctgcagcagtggatggagatggtggaacaggaggcaggagtggctctaccgcag cagcccgggctgaaagagaaagcctcgctgttggagagactgcgggtcattcaggccgat gtggaggtccactccacagcactgagccgcctcaatgagaaagccacagagctgtatgag aagacaggagaccaggcgtttgcagagggaccaaaatctgacttcaacacacagttcacc aacatcactgcagtcattaaaagtaaagtccagcagatggaggagattgtcaaagaacat gagcagtacatggagtcagtgcgggacctgaacgactggctcacctcggctaaagaagag ctccagcgctggtcagacatgtctggagacgcagcttctgttcagaggaaactctctaaa gtcagaggtctattagactccaggaagcagggccgtgagcgtctgacccgagtccagagc tgcggtgccgccacacgcgaccacacgtctactgtgggctgtgaggtcctggagcgggag gaggccgggctgctctccgcctgggagcagtgggagcgtggagctaaacacgtgtgctcg ggtctggagggcgttctggctcagatggcaaactcagagcaggagttcaacagtttggct gcgcagctggagcaggacctgcaggagttcagcagcaaactgcaggagtggcgcatcaag ctgcagcaggtggaggagatgagtgcaggagacgaggcggtgcagggctggcagatagcc aaggacaccctggaagcactgctgaacgtggagcccatgtctgacaatctgaagtgtcag ctaaacgatttgtgccgtttctccagagatctgggcgctcaatctgaaagagtgtctgca ctcattaaagaatacaacagtctgagtctccaggcatctcgagagtgtcagggaaaggag aagctgctggagcagaggtttcgtgctgcttttcgagacttccaacagtggctggtcaat gccaaaatcaacacagccaagtgttttgacgtgcctcagaacctggctgaagcgtcatcc agcctgcagaagatccaggagtttctgagtgaccgagagcaaggccagggtaaactgaac acagtggcggccagtggagagctactgatgagcatcgctgctaaagacagagtggagtca gtcagagcgaaaatcaacacagccagagaagactggaaaacactcatgaccaacctgcac cagagagagaacgccttacagaatcttcaggctcagatgcgggactttgagacgagtgtg gagccccttcaagactggctgaatgacactgaagaagctgttcaggagagcagcagtcga ctgcaggacctcacggctaagaagcaggagctgcacaggttacagtctctgctagaggaa ttagcctctaaggagcctcagctgctcaggttgagggagaaggcccagcagctgtgggac ggacacacggccggaaagggctttgtgcaccgtgtctcgcagctctctgctcagtaccta gctttaagcaacctgaccaaggagaaagcctccagaattgagcgtatggtgtccgagcac cagctgttctctcagggcctgaaggagctgcagaactgggtgtccgacaccagtcacatg ctgcaaacctactgtactcccaccgcagacaagaacgtgctggacagcaggatgatcaaa ctcgaggctttactgacagcccgtcaggagaaggagatccagctgaagatgctgctgacc agaggagagtctgtccagagaaacacctctgctgacggggtcccgctggtccaccagcaa atcgaggacctcaaggactcctgggatggactgctgtcggcatctatacaatgcaaaagt caactggaaggcgccctatctcaatggaccagttaccaggaggacgtacgtcagtttgtg acctggatggaaactgtggaggagactttaagctcagcggataaacagtgttcggagatg agagacaaaaccaccaatctgggcaaagccaaattgctcttagaagacgttttaagtcac agcagcgtcttggacgtcatatctatgaagggatccaacatggccgagcactacgtcacc cagctggagattcaggacttgcaggagcgctacaatattgtcaaagataaagctcagtgt gcggttgctaaagcggaggagctggtgtcggctcatcaggagtaccagcacagcctgcat gagtttaaagactggctggagcagcagcaggagagactgagctgctacacacagctggag ggagacacagagatgctggaggacacactgcgaaaactacaagagctgcaggttcactgt acagaaggtcaggctctcctcaacactctgctggtgagccgagagcaggtgattccctgg ggcgtcccacagctggaggaccgatgtctggagggcgtccagcaggagtggggctcgtat cagacccggctcactgacaccagatctcagcttaacagcgctctggccaaactgcggcag atcgagcagaagttccagcggctggacaactggctgaaggggatggaaagtaaaggccag ttacgcactggacgccgctctgacagagcaaccaaagaggcccagctgcagctcctgaag ggctggcatgaggaggtgttggtctaccaggaggagattgagggtctcagtgttttggcc cagcaggttttagaagagacgcccatcagcagcagagtcagcactcgagccacacagctg acctcacgctatcatgcactgctgctacatctgctggacactataaagcagcttaaggag gaagtgtcctgcattgaagaatctcagagtgtcttcagcacattctctgaatggttgaac acagcacagaagaacttcagtagcgtgaccaccaccaacattgatgtggtcgatcgtgct gccatggagaagaagatgaaacaactagaggctctgcagggcgacatggagctcgggcac actttcctgaagaccatgcgtgaaaagaccgatcgtgccatgatgttcctggaggagccc gaagcagagcagctgaaggaggaggtggacagcagactgtctcagctggagacactaatc agagctctgcggtccgagatcagcgccactgagaaatccatacagctctctaaagatttc ctggacaagtttaagactcaaacacagtggctttcagagacaaaatcactgctggcatcc cctgtggagccaaaagcagaactctaccaaaagaaggctcagttggccaaatataagaca atccagcaaaccatccagtcccatgaatcagccgtcaaatcagtaatcgagaaaggagat gctcttcttgaaaccatccgagacccgtccatcagcgagaacatcagcaagctgaaaact gactatcaagacctatgcgctgatgctaaggctcgtgttcaaagtttgacagagagcgtg agggagcatgaggactataacagtgaactgcaggaagtagagaaatggctgttacagatg tcaagcagactcgtcacctctgattcaatgcaaagtggcaatctggagatggccacacaa cagcttgccagacacaaggcaataatggaggagatcgctggatttgaggaacggttgagc agtctgaaggataaaggtgatcgtctcgtcagtagctgcacagagcaagtccaggccaag atcagtcagcagatccaagcacaccagcagggaaccagagacagttattcagctatctgc agcacagcgcagcgtgtatatcagagtctggaccgtgagctccagaagcacgtcagccat caggacactcttcagcagtgtcagacgtggctctccactgttaaagaggagattcagatg cagccgcaaactccctatggcctgcaggaggctctgaaacaggtgaaacacttcagggcc ttacaggagcaggccagcacgtatctagatctggtttgctcagtgtgtgatttgtctgat gagtctgtgagagccacagctgccaaaatacagcagaccaaaacaatgattgaggagagg atgagcacttctcaagagctgtcagatagctggagggagattaaagagcaaaaacaggaa ctctcgacactttttcaggacatggagcagcaactgcaaagtctctccagaagacctgct gagctggagcccaaaattgcccaaaacatgctcgatcaagccagagaaattggccaacag cttcaaaacagacaaagcactctgacaaagatgacagagcttgtgagtaagctgacagaa gggaaggagtctcctgagcatacagagatcggtcgactgagtcacgcatggctggaactg tgtcatcaggccaacatactacagactcaacgagaagaagatctgaagaggactaaagag tatcatgactgcatcagtgccatggaagccctctttgaacaggtgtccaaggaatgggac aacctggccagaactgatgctgaaagttcatctgatcatctggaggctcttcgcaagctc tcggttgttcttaaagaaaagaaaagcacacttgaggatctcaaagagcagaagcaaaaa gtaatgtaccatctaaacctggatgacaaagagctggtgaaagagcagataggccacttt gagcagcgatgggcccatctagagagcctcattgagaggaagattcaggactccattttg acacttgaagacatggggcaagttgaggcccgcttgagggaagctcgtgaatgggctgag gagcagcagccgaccctgtctgaagccatgaagatgagtcccccaccggagctagcgcaa agtttcctctttgaccatctcagcatatgcagtgagctggaagccaagcagcttctgctt gcccaggcaataggtgatgcagatagggttttagcacatctggggctaaacgaaagacaa agactgcagcagctcatttcagaaacgcaagcagaagtagagtgcttgagcgtcaaagta gctcagcgtaggaaacacctaagcaaagcttttactgagagaacacagttcttgctggct gtgaatcaagcgattacctgggtccagcagaatgagaaaaaagcacaagcagaagagtac attgcccttcttcctgatgacctttcaaagcaggtgagaacatgccggaacatccagagc agtttgagagcctaccagagtgagctgacctccctgtggtcacaaggcagggatctgatg aaagacgctgctgaagaagagaagacagagatgctgcgtaagcttcaagaactgcaaagt atctttgaagttgccctgcagaagtgtagccagagacttcaggagctggaaaaggtgttg gtgaccaggaaatactttaaggcagatctggagaagatatgccaatggttgaaacaagcc gatattgtgaccttccctgagataaacctcatgaatggagatgcagaattatgctcacag cttacaaaataccaacagatattggatcaagctatggaatttgagaacctcctgctaact gtgcaaaggacaggtcaagagatacttcccactctcaatgaagtggaccattgctacttg gatgagaaattgattgctcttcctcaacagtacaataatatcttgggacttgccaaagag aaacaggagaaaatacagcaagccattcttgcccgacaagaatatgcctcctttattgat gttacccacaaagcactaaaagaacttgaagaacagttccacagcttggggacgcagcct attggccttaagactgaagaagttgtgaaccttcaggctgactataaagctctccttgag gaactgaccaatcttggacaagccgttggtgaacttaaccagaagaaagaaggattccga agcaccggtcaaccttggatgcctgaagaaatgacccaactggttagcctttacaatgga ctcaaaagattaattgaacagagggtagaacatcttgatgacactcttgaatctttcgag gaccatcaagccatggctatgcaggttgactcagagctgaaagccaccaaagagcaactg gtgaaagtcaatgccgagacgcagtcggctgaggagagattgaagaattatcatgcccta gccgctagtcttcaaggtgccagctctcacctcactcgactgatggagcagatggataac ctggtatcccacatggataccgctgcacatgaggtttcaaagcagcgggtgacctcttgg caggaagagcttcagtccttgcagtcatctgttggagaacttattgtggagtgtgaaaac aggttcgtgcagagtaaagactttgagactgaagtcaatcgaaccttaacctggctccaa caaatcaaagatgaacttggctctgaggtggtggtagatgtcaaagttgaaaaggtccag gaagaaatccgaaagcaacagatcatgcaagaggaagtacaatcaaggctgaggatagtg gcagctttgagcacaagagagaagcagaaatacaccagtgccaatgagctcgtcccagct catgtggactcaagtctacaagagatggccaagctggaggctgatgttcaacgtgccctc agctctaaacagattacattagagcaagctcttgtcttgtgccagaagtaccactccaga atgcaagcagcatgtgaatggctggaggacgctgtgggcttcttgcagcaggccagtctt ggggtggatgtagagaactacgaggagtgtttgaggcaacaagaggacatcatggccact gagcaagagttcctgggggttctcgaggagctagaatctttgccaccgcaacttgaaaac cttgtcaaccctacagccaaagagcagcttcgactgagtgtggagtctgcacagcaaaga ggcgtggaggtcagagaccagctgcagtgccaccaagacgtcctaaacagctgtgttgct cagtggaacttataccaggaagccagacagacagtcattgagctgatgaatgaggtggag aagaaattaacagagttttccacagccaaggctgcaacaaaccaagaagctgaagagaaa ctcaggagccataagtccttagtatcaatggtgaacagtttccaagaaaaattgactggt ctggaggagcaagcatcccagttagagcagattggaagtgatgccagtaaagcaactata agtcgatccatgaccaccgtgtggcagcgctggaccaggttacgcagtgtagcccgaggc caagaaagggtgctggaggacacggcccatgaatggaggactttcagggaaaagatgatg aaagtaagatctctaacggaagaactgaaggcccgtgttcctgattgcactgctgaaaaa gcctccaaagccacactgcaatcacatctggaccagtacgagctggttggtcaggatctg gagagggagctatcgtctctaactctcctgagacagtacgctcttagtctgatacatgac gtggaggtgtctgtgccagcggctgatcatgagcagctgccaagtctgaaggagatcaaa gctgtgcaagatcaactggagagtctcctgcagaaggccagggcgggtaaatctcgggtt cagcaggagctgtcggacagggaaggtgtggagagaggactgagtcttgtcaagagctgg atccaggactccagggagctcctgctaaaccccacgtctgatttggacattctgtctcaa gaactggaggtgatgcatggagagctgatcactcaccgtcagaatgtggacaagctcgca gagcagcagcaaagcaaatacttagacttgtacactattttaccatctgagatctcaatg cagcttgctgaggtatctctggcactgggatccattgaggatcaggttcaagccagggag agagacatccagaagtccagagtaatcaaagaagagttcaactccaggatacatgacgta tctgaaaaaatgaaggccgtctctacagctctgaaggaaaaggccacggatattgatcag gccaaagatgaggccagacgtctctgtgatgaacttgacggctgtggaagaactcttgct gagttggaagctgcagtgcaggattttggtcgccgtaaccctctaatagccagacaactg gctgatgcaatcgctaaattgcgggagatccatcatcacactcttcgactggctgaatat aaaacaatatggctgaagaaggctgatgcacatctggatgagtacaatgagatgtttgag ttcatagtgaagtggacagaccgagccaggagtctggtgaaggccaacatcatctggaac tcttcctcacacctgcaagagcagatcaggatgtatcaggctgttctacgcgagtcacgt gagcttcatggtgacctggactccatgcaggagaaggtggagatcctgtctgagacgctg caggtggaggcgatgggacagcaggtgtcagaactaagccgtcacactgaagagctggag cagagcatcagatcccgcctgcagagtctacaggacgcagcaaaggatatggagaagttt gagagtgaagtgaaggccctgcatgtgtctctggaccaggttcaggccaccctcacatct cctgaactggcccgactgagtctaaaagagcaacttactcaaagacagcgtttgctggca gacatggagagtttcaagcagcaagtggagaccgtgcaggagtgtcagagcgctctgaga gtcccagaggaagtggtcaccagtttgtccatctgtcgcacggctttgaatctgcagcag gaggccagtcagctgcagcacaccgccatccagcagtgcaacatcctgcaggaggctgtg gtacagtatgaacagtacgaacaggaagtgaaaaacctgcaggttatgattgaagatgct catcgggtcattcaggaccaacctgtgaacaccagcaacatccaagagctgcaggcacaa attaaccaccacgaggaactggctcagaaaatcaagggctaccaggagcagattgcatcc ctaaactccaagtgtaagatgctgacagtgaaagcaaaacacgccaccacactcctgaca gtgagtgaagcagagggattaaccgagagtctggaggagctggacggtgaacttattcaa agaaaatcacagtcgcaagtctctatgtctgctggccgctgtcagtctctcctgtctcct gtgactgaggagtctggagaggagggcgccagtgagatctgctctcctgctttctgtcca tctccttctgctagcactaacactgaagctgtcattagcaagatgtccatgggaagatcg agtctcaccagagcgccggtccaggagctgtacaatcctgcactggagtctgtggccagt ttagatgatctccagcgctcgtgggagaccctaaaaaatgtgataagtgaaaagcagaag acgctctacgaggctctggagaagcagcagcgctatcaaggctctctccaggccatctcc agtaaaatggagtcaatcgagaccagattgaatgagccaccaatgcacgatctcagtcct gatagacagatgatcctacatcagaatcaaatggaggaaatcgtcagactgcaggatgat atcgatgagctccagtccagcttcactgaagagctgtacaatcctgatgccgtggattca gactctgcagatcagctggccatgcagtcctcactcactgtgctggcggacagaatggcc accatacacatgaaagcttctggaaaacggcagattcttgaggagcgtcagagtgagcgt gtggaaaagcagcagcaggcgcaagcattacagcactacctcaaccaggcagaccagctc gaccaatggctgaagagcactcacggttacatcgcttcctgctctcaggactcagacgca gaagagcaactcatagactgtcagaacatgctgctggagatggaggaaaaggtgctggct ctctccgagctgtcccgacacagcgagagtctcctgctggagggacggcccgagaacagg gaggacgccgggcagctggcccggaaactgcgcacgctgaaggggagcctgctggagctg cagaggatgctgcaagacaagcagatcaacctgcaggcgactttaatttgggaggagttg aaaggccctcaaagagcaagtgattcccttcaggaagcgtcagactcgagtgaatcagac tccactctctctcagagtccaaacatgcaggactggctggcccaggcccgcaccacacgc agcctccagcaccaggacacccttcaaaaacagaaggagcttgaagagcagcttgcggag cagaagaagctgttgaagtctgtagcgagtcgtggagaggagattctcacacagcaggcg tcacccgtcagagccagtgcgacagagacgctctctcctgatgtagagctggaaggagac agtgaggctgtgaaaaagcagaggagaaagagatgggaaagcctgaagaaagacatggcc accaaactacagctccttatgaacaccctggagcaggacagcaaacagccgttttactcc agaactgcttgtgtgaagacggcggctccagctccggtttataagagagagacacacgtc caggacaagtccaacctgatgtccctgcacaatggattcagtcagacaatacaggaaatg acacctcaggccacagagcgagaggtcgttctgatggagcagcagctttattcagccatc acagccacttcttcttgggtggatgatgtggagaacacactgttttctggccctgcgctg ctgacggagaacgcagacacacaactctccaaccatgagactctgggtaaagaagtgacg gaggtgacacaggaggtgggacacagtcaggggttgatcagaggatcagtgggtctgtct gaggatgagcagagcctgatgaaggacactctggactgcctgacccgacgcctaggagcc ctggactcagctctggaccgccgctgtgaatccatgcggagcagaatgagggaactcagc actttccagacggagctgcagcggctctttacagctctcagtgaaagcaagtttcagatt atccagaaaatggcaggagttcttgaccacacaacaactaaacagattgaaaccattgca gaggtggaagatacactgaaagactttgagcacagaataacagagttgaaagccagaggg gcggagctgcagccagaccagttctccaccaatgagctgctgaagctgcaggatgcttat gaggagctagtgatgacggtgggctcgagacggagtggaataaaccagaatatggctctg aaaaatcagtatgaacgagttttgcaagatctgattgatctggtggacacagctcatgat aagatggccgctgaccagaagatgattgccggctcagtcgaggacgtgcacaaccttcta gacaaacacaaggagtttttccaaggcttagagtggcatatggtcctcaccgagacattt tacaagaaaattagtgcctttgttttgccacgtgagcgtcagactcttgaagagacgctg gctcgtgctcaggatgtgctgaaacaagcgcataaaaaaggagttgagctggagtgcgtc tctgagacatggagtcgtctagttttggactatcagacgctgtaccgactgctagaggtt gtggaggggagtctgccgagtgttggattagtggaagagaccgaggagaggcttaatgaa agaatacagctttatcaggctctgaggtccagtctgacagagcaccaacacaagctccat caggttctagaggagggaaaacatcttctgtcatatgtgagctgctcgagtctggagaac cagctgacggttttaggagaacactggctcaacaacaccaccaaagtcaacaaggagctg cagaacctccagtccatgttgaagcatttaaccaggtataagagtgagtctgttgaactg agccgctggttactggaggctttggagcgtttggagttctggaacacacagtttgttgct ggacctcaggaactggagacagttaaaggccagctgtcggcttttctggagttcagtaaa gaggtggaggctcgctccagtctgaaggcctcagttctaaatgagggaaatcagctcctc agactgaaaaagatggacacagcgtctctgcgggctgaactggcctgtctggactctcag tggtctgaactgctcacccgcattcccatagttcaagagaaactccaccagtctcagatg gataagctggcatcccgtcatgctataacagagctggtcaactggatttcgctgatggaa agagtgatagaagaggatgaggagaatctgaaaggagctgtcgggtcaaaggtcattcaa gagtacctgcagcgatataagggcttcagggtggatgtgaactgcaaacagctcactgtg gactttgtgaatcagtcagtgctgcagatcagcggtgcggatgttgagagcaaacgcagt gataaaactgattttgctgaaaaactgggcgccatgaactgccactggcagatcctgcag acacgcatcacagagagggtgcagtatctggaaggcttgttggtgtcttgggtggaatat gagggtaaagttcagggtctgcaggcgtggctggatgctcaagaagaaagacttaagagg aaacacaggattgagaacttatcttctgtgcaaaacgcactcaaagactgccaggagatg gaggtgatggtgaaggagaaggagagagagctggagagagtggaggaacaggcctgtgct ctcgtccaaaacaagactgacgaggcctgtgctgtcgtgatggagtctctacgagccctc aataacacatgggccaatctggaccacctgatcgggcagctcaagatcagcctgaagtct gtccaggacaagtggaatcaatacaaacaagcgtctgaagagattaacgggtacctgacg gagggccgctactctgtgtcccgctaccgtctgctcacgggctctctggaggcatcacgg ttacaggtggagagtctgcagaacctgcaggaggagcttgagaaacaggaaagcagtatg aggaagtttggatcagtcacacttcagctgctggaggagtgtcatccgtctgtgtctgac acactcaataacacactcaaagacatcaatgctaggtggagcagtctacaggaggagatc gtggagcgtctgaagagcagtaaggctctcctgcagctctggcagagctataaagatctt tatggacagagtgactccagcgttcagacactcgaggagaaagccaaccagatgctgaag acagccagccataaagacatcacagaggaggaggtgtctgcctggattcaagactgtgct gagctgctgcgctctcaggctccggttcaggcgtctctgcaggttttaatggagttagga gaacagctcaaacagcaggtggacacatccgctgtggcctccatccagtcagaccacctg tctctcacccagcgcctcagtgtggtggagcagagcctgagtcgacagcaggtggcgctg caggctggagttcgggactatgagacgtttaatgagcagctggactctctgtcccgctgg attgtggaagctgaggaggttctgaaaggacaagatcccaatggatcctctgaccagtca ctgatccaggaccgcatggaggatctaaagaaacagatgctgaagttcagcagtatggct cctgatctggagagactgaatgaactgggttacagactccctctgaacgactcggagatc aagcgcatgcagaacctcaacagaagctggtccacaacttcagcccagaccaccgagaga ttctgtaaacttcaggcgctgttactccagcagcagacatttctggagaagtgtgagacg tggatggagtttttggtgcagacggaggagaaactggccgtggagatttccggaaacttc cagagcctgatggagcagcagagagctcatgagctgtttcaggccgagatgttcagcaga cagcagatccttcactccatcatcagtgatggacaacacatgctggagcagggacaggtg gatgacagagatgagttcaagctgaagctggctctgctcagtaaccagtggcagggtgtg gtgagacgggcgcagcagcgccggggcatcatcgacagtctcctgcgtcagtggcagcgc taccgggagatggtggagaagctccgtaagtggctgctggaggtcaaccatcagacccag agcctgcaggcgggtacaccagtgccactgcagcaggcacgagccatgctggatgcagtt cagctcagagagaaggttctgctgagacagcagggcagctacatcctgacggttgaggct ggtcgacaactgcttctgtctgctgattcacgagctgaagccgctctacaagaggagctg ctcaacattcaggagcgttggagaaatgccaacatccgcctggacgagcagaaaaaggag ctggccgtcctgctcagggactgggagagatgtgagaaaggaattggaggatctctggag aagctgagagcatttaaacgacagctttcacagccgctgccagatcgccatgaggagctg caggcggaacagatgcgctgcaaggatctggagagcatgtttgacggctggaaggaggat ctgacccatctgacagtgctgagagagtctctgtccagctacatcagtctggaggatctg cgtgtgctgcaggaacgcattgagctcctgcaccgccagtgggaggagatctgtcatcag ctgtctctgcgcaggcagcaggtaagcgagaagatgaatgaatgggccatcttcaataat aaatacaaggagctgtgtgaatggctgacacaaatggaaagcaaagtatcccacaacgga gacatcagcattgaagagatgatcgagaaactgcgcaaggactatcaggaggaggtgtct gcggctcaggagaacaaacacgagctccagcatctgggtgaacgattagctcgagccagt cacgagaccaaagcctctgacattgaacacaaactcagtaaagtcaatgaacgctggcag cacctgctcgacctcataggagccagggtgaagaagctgcgggagactttagtggccgtt cagcagttggataagaacatgaacagtctgcgctcttggctcgctcacattgagactgaa ctgtcccgtcccattgtctacgacacctgcgactaccaggagatccagaggaaactcgat ctgcagcaggagcttcagagagacattgagaagcacagcactggtgtggcgtctgtgctg aatctgtgtgaggttttactgcatgactgcgacgcctgtgcgactgatgcagagtgcgac tccatccagcaggccacacgcagcctggaccgccgctggaggagcatctgtgccatgtcc atggagaggagactccggattgaggagacgtggcgtctctggcagaagtttctggatgat ttctctcatttcgaggagtggctgatgttgtcagagaaaacagccgctctgccaaactct tcaggtgtcctttacaccattgccaaagaggagctcaagaaattcgagacgttccagcgg catgtgcatgaaagtttgacacagctggagctgatcaataaacagtaccaacgactggcc cgtgagaatcgcactgacgcagcctgtagtctgagagaaatggcccacaatgccaaccag cgctgggataacctgcagagaagggtgtcatccgtcctccgcagacttaagcactttatc agtcagagagaggagtttgagacggcgcgggactgtattctggtctggctgacagagatg gacctgcagctcaccaacatcgagcatttctctgagtgtgacgtccaggccaaaatcaaa cagcttagggcattccagcaggagatcacactgaacacgggcaagatcgaccacattttc cagcagggtgaagctcttctggagaaaagtgagccaatcgacgctgctgtgatcgaggag gagctggaggagctgcagagatactgccaggaggtgtttggacgtgtggaacgatactac aagaaacttatccggttaccgttgacggacgatgagcatgacatctcgttctcagaccgg gagtttgatctggatgaaggtgctgacgtgtccagcttcccctggagcgagcgtttggga gacggttttctgtctcctctgccgtcctctagccgatctgctccgctgcgggccgaacgc tcgggtcgggacactccggccagcgtcgactccatcccactggagtgggaccacgattac gacctgagccgtggtctggagagcgccagcagggccctgtcctcctctgaaacaggagat caggcagaggatgatgggtacctgcagggctcagcatctgcactctcagatgttgtgatt ccagagagtcctgaggcatttctaaaacttactgagcaaactctgagatccagcgctggt gacgctggatctctggagactcacatccgacagctggataaagctctgaacaccagctgt ttccacctgcagcagacggagaacatcatacgcagccgaacacccaccggccccgagctg gacgccacatacatgggttatatgcggcttcttgaagaatgtcgtggcagtattgatgct gtaaagcgggtaggatttgagctgaaagatgaggacgacaagatatcaggcttcgtcaat cccaacagctcagagtcccagacatcaggagtaatcgagcgctgggagctgctgcaggct caggctctcagtaaagagatgcgcatgaagcagaacatgcagcagtggcagcaatttaac tcggacctgagcagcatctgcagctggctggaccagacagaagaagagctgcagcaggag cggggactggacctcggcacagacatacacaccatcgagttgcgcatcaagaagctcaag gagctgcagaaagctctggataaacgtaaggccatcgttctgtccataaacctctgcagt gctgagtttgtgcagtcagacagcgaggaggctcaagacctgcagcggcggctgaaggag atgaacaaccgctgggagaaactcagcagctcactggacgagtggaggactgcgctccag catgcactcatgcagtgccaggatttccatgagatgagtcacggtctgcttctgtggctg gagaacatcgatcgcaggaggaacgagatcatcccgattgaccacactcaggacagcgac accctacaggagcatcacaaaaccctgctgcaaatccggcgggagctgctggacacacag gtgaaggtggcgtctctgcaggacatgtcccttcagctgctggttcactcggagggcagc gactgtctggaggccaaagagaaggtgcatgtgatcgggaacagactcaaactgttgctg aagggggtgaccagagacatccgagaactacagaagaccctggacatcagcagcagtcaa caggatttgtcatcttggtcatctgctgatgatctggatacatctggatctctgagcccc gtgtctggacgcagcacaccgagccgccagcgaccgccacggggcaaaagtagtgtgtca gagcccggagcctgtgtgagcagtccacttcacaggtctctcaacgccgctggatccgct tcctccccttctgaagatgaagagccgccatcttggtgcagaagcttcctgaagcgggtc ttctgggccgcgctgcccctgcagatcatcctgctgctggtgctgattgtggcctgtctt gtgcctacggctgaagatgactacagctgtgcccaactcaacaacttcgcccgctccttc cacccaatgctcagctacaccaacggccctccgccaatatga

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