Drosophila ananassae: 6495234 Help Entry 6495234           CDS       T01059                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism dan  Drosophila ananassae Brite KEGG Orthology (KO) [BR:dan00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:dan04040]     6495234    04990 Domain-containing proteins not elsewhere classified [BR:dan04990]     6495234 Ion channels [BR:dan04040]  Voltage-gated cation channels   Ryanodine receptor    6495234 Domain-containing proteins not elsewhere classified [BR:dan04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    6495234 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  6495234 NCBI-ProteinID:  XP_032306929 LinkDB All DBs Position Unknown AA seq 5131 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVTLSCTATGERVCLAAEGFGNRHCFLENIADKNVPPDLS QCVFVIEQALSVRALQELVTAAGSETDSQVGKGTGSGHRTLLYGNAILLRHHNSDMYLAC LSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLH TTKENEQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWG REAGQNIVVYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNDSN ELILVKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCETSLW LSYKSYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFI TALETLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDL FQEEGVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGR VDGSSMYQKWYFEVTMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYS FGFDGAYLWTGGRKTLVVDALPEEPFIRKGDVIGVAIDLSVPIITFTFNGGKVRGSFRDF NLDGMFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPHQILSLDPCFYFGN LSKNVLAGPWLIEDDTAFVPKPVDTTGVSLPSSVDQIKEKLAENIHEMWALNKIEAGWSW GEHRDDYHRIHPCLTQFEKLPAAEKRYDNQLAVQTLKTIISLGYYITMDKPPARIRPVRL PNEIFMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSD NHRSPHLVPYAKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFA AFRTYRVEKNYAVTSGKWYFEFEVLTAGPMRVGWARADCYPGAMLGSEDTSWAFDGHNVT KMHAGSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGF VPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENT EEMPDCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLSLPVTCMSEFINEQEKA RRWDEIKNRQYRLMREAEAAAQMQVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEA DHMMRGPSRPPRKGSLTRNITFETDMSAALDEMHRSSSVLDMNGLGDEMDDKKKRGRSPF KFFSKKSRDQSREKMGRSQDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNADIPPSPVP QGPKQLSGSTLGQPPVESSGEEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYH LHSKEFNKNKVRRGSVYIENDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGMF VGCFVDTATGIIRFTCEGKDTSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPL SAAVLPTSDKHISPQSPPRLKVQCLRPNQWARVPNTALQVHALKLSDIRGWSMLCEDPVS MLALHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLL YAIRSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGPELKELYSEDEMQHSL RSLITESVRPQLRMTEITPPVIATSSLPSVSSEPIPNIDQLYSPKFPLEVVRQFVMEALK DAVEINQVHNRDPIGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWDAAFE REGKDEHRKGLLTMKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLR RYIEIKQSDLPSAVAAKKTKEFRCPPREQMNQILCFKNLEADDQDNCTCGLELRGRLGDF HDSLMQKVSLNALQEPDGVEGAAIEEIKTGPITKIYNFINTVKELEEGPKEVEEPEKKTP EEVFRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVGELVRALEKTYVINNRARD DVAEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAV MMNTLGRRAQAQSDAPTQTEVAEGAPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFD HFDFLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQS NSELVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALR GEGEGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPLPESDEDEDYIDTGAAIL NFYCTLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGE EKPKSDMPSGLLPNNKQSIVLFLERVYGIETQDLFYRLLEDAFLPDLRTATILDKSDGSE SDMALAMNRYIGNSILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAV SDFLVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGS YGASSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDED YYGRQMGAPDQPQYMPNPIDTTNVHLDNDLNSLVQKFSEHYHDAWASRRLEGSWTYGEIR SDNDRKHPRLKPYNMLSEYERERYRDPVRECLKGLLAIGWTVEHSEVEVPLNHRGSTRRQ SKPQIHDFQNEGSPFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCG GVIHPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGATQAAVEL RFSYSLLEKLIQYLDRATINMKLLKPSTTFSRRSSFKTATRDIKFFSKVVLPLMEKYFST HRNYFIAIATATNNIGAASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVK GIDARTLTKNCPEFIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVN QVVLPVLTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDATLTHDRKYLKTEIE RHRPALGSCLGAYSSCFPVAFLEPHLNKHNQYSLLNRIADHSLEAQDIMVKMESCMPNLE TILSEVDQFVESDKTYNDAPHIIDVILPLLCAYLPFWWSQGPDNVSPTSGNHVTMVTADH MNPLLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTEN MLHKEDSMRGFIKSATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNI PEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGVPAVG GKVKKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMP EYDVIEFARNQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNANEKGKDK TTETVDRIVAMAKVLFGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHR ACNIFARSYYEQWLQEENVGQEVMVEDLTQTFEDSEKSKKDEEETDSKPDPLTQLVTTFC RGAMTERSGALQEDLLYMSYAQIAAKSCGEEEEEGGDEEGGEGGEEGEGTSIHEQEMEKQ KLLFHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLK EKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCALFRF IQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAG KANFFKAIGVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHS SQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLK LADLIESPSFHEIDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEGKIDYRA FVERFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSS KRIERVYFEIKDSNIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTH ASGLMATDDGGGNVKRDTAYSSYMSEEEEERAARDPIRRTITAVKEGLKFGVHMLSPANI KHQIGVMQTKSIPELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAPEQEEEP VVEEETFGRALPPLPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEGGESSPE DGAAPAGELVEGEPHQEPISIVDLLGGEAAKKAAQERQEAQKAQEAAMASIEAEAKKSSS APQETPAVHQIDFSQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTTLVEESDG SGEEELILGSGSGGGADITGSGFGGGSGDGGSGDGEIEDDVPELVHVDEDFFYMEHVLRI AAMLHSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFDGLFIAEQPEDDDFKSHWDKLV ISVKSFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSAFAAQESEETGIFKYIMNI DWRYQVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVT HNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHLYKGVR AGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKD NMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWN MYQQRSWDFFPVGDCFRKQYEDELSGGGGGG NT seq 15396 nt NT seq  +upstreamnt  +downstreamnt atggctgaggcggagggaggctccgagcaggatgatgtttcattcctgagaacggaggac atggtcacgctctcctgtacagcaacgggagagcgtgtctgcttggccgccgaaggattt ggtaaccggcactgtttcctggagaacattgccgacaagaatgtgccgccggatctgtcg cagtgcgtcttcgtcatcgagcaggcgttgtccgtgcgagccctgcaggagctggtgaca gcggcaggatccgagactgatagtcaagttggcaagggaactggatccggacacaggaca ttgctctacggcaatgccattctgctccgtcatcacaatagtgacatgtacttggcctgt ctgtccacctcgtcgtcgaatgacaagctatccttcgatgtgggtctgcaggagcacagc cagggagaggcctgctggtggacagttcatccggcgagcaagcagcgttccgagggtgag aaggtgcgcgtcggtgacgacctgatcctggtgtccgtggccacggagcggtatctgcac accaccaaggagaacgagcagtcgattgtgaatgccagcttccatgtgacccactggtca gtgcagccctatggaacgggaatttcgcggatgaagtacgtcggttatgtttttggtggc gatgtgctgcgcttctttcacggtggtgacgagtgcctaaccatacccagcacctggggc cgtgaggctggtcaaaatattgtagtttacgagggcggcgtggtcatggcccaggcacgt tccctgtggcgtctggagttggctaggaccaagtggacgggtggcttcatcaactggtac catccgatgcgaattcgccacataaccactggacgctatttgggcgtcaacgatagcaac gaactgattctggtgaagaaggaggaggcttcgatcgccacgacgactttctgcctgcgg caggaaaaggacgacgagaagaaggtgctcgaggacaaggatctggaagtgatcggctcg ccgattatcaagtacggcgacaccaccgtcatcgtccagcactgcgagacgagcctctgg ctcagttacaagagctacgagaccaagaagaagggcgtgggcaaagtggaggagaagcag gccatcctccacgaggagggcaagatggacgattgcctcgacttttcgcgctcccaggaa gaggaatcgaagacggcccgtgtcattcgcaagtgcagcagtctttttacccagtttatt acggcattggagactcttcagtccaatcgccgacactccattttcttccagaaggtcaac ctcaacgaaatggtcatgtgcctagaggacttgatcaactacttctcgcaacccgaagac gatatggaacacgaggagaagcagaaccgcttcagagctctgcgaaatcgccaagatctg ttccaggaggagggagttctcaacctcatcctggaggctattgacaagatcaatataatt acatctcagggcttcctggccagcttcctggccggagacgagactggccaaagctgggac ctcatctccacctacctgtaccaactactggccgccatcatcaagggaaaccacacgaac tgcgcccagttcgccaacagcaatcgcctgaactggcttttttcgcgtctgggatctcag gcctccagtgagggctccggcatgttggacgtactccactgtgtgctgattgactctcca gaggccctgaacatgatgagggatgagcacatcaaagtgattatctcgctgctggagaag cacggccgcgatccaaaagtcctggacgttctctgttccctgtgcgtgggtaacggagtg gcagtgcgatcctcgcagaacaacatctgcgacttcttgctgccgggcaagaacctgctg ctgcagacccttttagtggaccatgtggccagtatccggccaaacatatttgtgggccgc gtagacggctcatccatgtaccagaagtggtactttgaagtgaccatggaccacatcgag cagacaacgcacatgatgccccacctacgcattggttgggccaacacctccggctatgtc ccgtatccgggaggaggcaagaagtggggtggtaacggcgtgggagatgacctctactcc tttggcttcgacggcgcctacttgtggaccggcggccgcaagaccctcgtggtggatgcc ttgcccgaggagcccttcatccgcaagggcgatgtcattggcgtggccatcgatctctcc gtacccatcatcacattcaccttcaatggtggaaaggtgcgtggcagcttccgggacttc aacctagatgggatgttcttccccgtaatgagttgttcctcgaaactgagttgccgtttc ctgtttggcggagatcatggacgcctgaagtttgctcctcccatgggattctcggctctg gtgcagtgcctcatgccccaccagatcctcagtctggatccgtgtttctactttggtaat ctcagcaagaacgttctggccggaccgtggctcatcgaggacgacactgcctttgtgccc aagcccgtggacacgacgggcgtttctctgcccagctctgtggaccaaatcaaagagaag ctggcggagaacatccacgagatgtgggctctgaacaagatcgaggctgggtggtcgtgg ggcgagcaccgcgacgactaccaccgcatccatccatgcctaacccagtttgagaagctg ccggcggctgagaaacgctatgacaatcaattggctgtgcagacgcttaagacaatcatt tccctgggctactacataaccatggacaagccgccagcccgcattcgtccagtgcgccta cccaacgagatcttcatgcagggcaacggctacaagccggctcccttggacctcagcgcc gttaccctcacccccaagctagaggagctggtggaccagctggcggagaacacgcacaac ctgtgggcccgcgaaaggattcaacaaggctggacttatggcctgaatgaggacagcgac aatcaccgcagtccacatctggttccctacgcaaaggtggacgaggccatcaagaaggcc aacagggacacggcatcggagacagtgcgcactttactcgtttatggatatgttctggat cctcccactggagagggcaccgaagcccttctggcagaggcacagcgcctgaagttcgcc gctttccggacctatagggttgaaaagaactacgccgtcacctcgggcaagtggtacttt gagttcgaagtccttaccgccggacccatgcgagtgggctgggcccgggccgattgctat ccgggcgccatgttgggtagtgaggacaccagctgggccttcgacggacacaatgtaacc aaaatgcacgccggatccattgagcacttcggagtgcggtatgaggctggcgatgtcatt ggttgtttcatcgatgtcaaggagcaaacgatcagcttctcactaaacggagaactcctc atggacgctctgggcggcgagacaaccttcgccgatgtcaccgccgagggggtgggcttt gtgcccgcctgcaccttgggcgtgggccagaaggcgcgcctcatctacggccaggacgtg gactccctcaagttcttcaccacctgtggcttgcaagaaggatacgagccgttctgcgtg aacatgcgacgaccagttactcactggtacaccaaggatcaacccattttcgagaatacc gaagagatgcccgactgccgcattgacgtgacccgtattcccggtggcgcagacacccca ccgcatttgaaaatctcccacaacaccttcgagaccatggagaaggccaattgggagttc ctgcgtctgtccctacccgtcacctgcatgagcgagttcatcaacgaacaggagaaggct cgccgctgggacgagattaagaataggcagtaccgcctgatgcgagaagctgaagctgct gcccagatgcaggtgcagacccaggccgcccacatggaccacatgctcaagggaggcttc aacatgaacgacataaagggtctaacccgcaatttcgacgagcatgccgatgccgaggcg gatcacatgatgcgtggaccttcgaggccgccacgtaagggatccctcacccgtaacatc acgtttgaaactgacatgtccgctgccctggacgagatgcatcgctcctcctccgtgctc gacatgaacggtttgggcgacgaaatggacgacaagaagaagcgaggccgtagtcccttc aagttcttctcgaagaagtcgcgtgaccagagccgcgaaaagatgggccgttcccaggac acttccttggaacgccgaaacactgtggcccacggacgtaatgtcgtcaaccagcagatg accactcgagctcctactttgaggttaaataatgcggatatcccacccagcccagtgcct caaggacccaaacagttgagtgggtccactctgggccaacccccagtggaatcctctgga gaggagatgttcgacgccgagtgcctgaaactgatcaacgagtacttctacggagtccgc atcttccccggccaggatccaacccacgtgtacgtcggctgggtaaccacccagtatcac ctgcacagcaaggagttcaacaagaacaaggtgcgccgcggatccgtttacatcgaaaac gattacgagatggccatcgagcgaatcgaccgccagagttgctacgttgtgagagccgac gagctcttcaacgaggtgacccaggacgcctccggcaagggggcttctcagggcatgttt gtgggctgctttgtggacaccgctacaggtatcatcaggttcacctgcgagggcaaggac acgtcccaccgctggatgatggagccggacaccaagctgttcccagccattttcgtggaa gccaccagcaaggagatcctgcagattgagctgggccgcacacccaccactcttcccctg tcggcggcggtgctgcccaccagcgacaagcacatcagcccccagtcgccaccgcgtctc aaggtccagtgcctgcgtccaaaccagtgggctcgagtccccaacaccgctctccaggtg cacgccctgaagctgtctgacatccgcggctggtccatgttgtgcgaggatccggtttcc atgctggccctgcacatacctgaggaggatcgctgcatcgatattctggaactgattgag atggacaagctgttgtccttccacgcccactccctcacattgtatgctgccctctgctac cagtccaactacagggcagcccacgccctgtgccagcacgtggaccagaagcagctgctc tacgccatccggtcggagtacatgagtggcccactgcgccagggcttctacgacctgctg atcgccctccatctggagtcgcatgccaccacaatggaggtgtgcaagaacgagtacatc acaccgctgggaccagagctgaaggagctctacagcgaggacgagatgcagcactcgctg cgttctctgatcacggagtcagtgcgtccgcagctacggatgacagagatcacaccccct gtgattgcaacatctagtctaccaagtgtttccagcgaaccgatccccaacatcgaccaa ttgtactccccgaagttccccctagaagtagtcaggcagttcgtgatggaggctctgaag gatgctgtggagatcaaccaggtccacaaccgggaccccattggttggaccaatgagaat ctattcttaccactcattaaactcacagaccgcctgctcctggtcggcgtattgaccgac gaagatgttcagaggttgctggtgatgattgacccggaaacctgggatgcagccttcgag agagagggcaaggatgaacaccgtaagggactgctcaccatgaagatggccgagggagcc aagctccagatgtgctacctgttgcatcatctatacgacacccagttgcgccaccgcgtg gagagcatcattgcgttttcgcacgacttcgtgggcgatttgcagaccgatcagttgcga cgttatatcgagatcaagcaatccgacctgcccagtgctgttgcggccaaaaagactaag gagttccgctgtccgccgcgagagcagatgaaccagattctctgcttcaagaacctcgag gccgatgaccaggacaactgtacctgtggccttgagttgcgcggtcgcctgggcgacttc cacgacagcctgatgcagaaggtgtcgctcaatgccctccaggagccggacggcgttgag ggcgcagcgatcgaagaaatcaagaccggaccgataacgaaaatctacaatttcattaac accgttaaggagctggaggaggggcccaaggaagtggaggagccggagaagaagacgccc gaggaggtcttccgcaaagtgctgatcaagaccatcgtcagctgggcggaggagtcccag atcgagaaccccaaactggtgcgcgaaatgtttagcctgctgctccgccagtacgatacc gtgggcgaactggtccgtgccctggagaagacctatgtgatcaacaaccgagctcgcgat gacgtggccgaaatgtgggtgggtctcagccagatccgcgccctgttgcccgtccagatg agccaggaggaggaggagctgatgcgcaagcgactgtggaaactggtgaacaatgccacc ttcttccaacatcctgacctgattcgtatcctgcgcgtccacgagaacgttatggctgtg atgatgaacaccctgggtaggcgggcgcaggctcagagcgatgcccccacccaaacggag gtcgccgagggagctccttcgaaggagaaggatacctcccatgaaatggttgtggcctgt tgccgcttcctctgctacttctgccgcacgggccgtcaaaaccagaaggccatgttcgac cacttcgacttcctgctggacaatgccaatatcctgctggctcgccccagcctgcgcgga tccactcccctcgacgtggcatactcaagtctgatggagaacacagaattggctctggcg ctgagggagcactacctcgagaagatcgccgtctatctgtccagatgtggcctgcagagc aactcggagctcgtggagaagggctaccccgatctgggctgggatcccgtggagggtgaa cgctacctggacttcttgcgctattgcgtttgggtcaacggcgagagcgtcgaggagaat gcgaaccttgtcattcgacttcttatccgtcgtccggaatgcttgggaccggctctaaga ggagaaggagaaggtctgttccgcgccatcgtcgaagccaatcgcatgtcggagcgcatc tcggaccgctgcaagatgcaggacgaagccgagggcaccattgccggactgaacttcacg cacccattgcccgagagcgatgaggacgaggactacatcgataccggtgccgccatcctg aacttctactgcaccctggtcgacctgttgggccgctgtgccccggatgcctctgtcatc gagcagggcaagaacgagtccctgagagctagagctattctgagatctctggtgccactg gaggatctgcagggcgtgttgagcttgaagttcaccctatcgcagacagctcccggcgaa gagaagcccaaatcggacatgccatctggcctgctccccaacaacaagcagagcatcgtg ctcttcttggagcgcgtgtacggcatcgagacccaggatctattctaccgtctgctggag gatgccttcctgccggatctgcgcaccgccaccatcctggacaagagcgacggctcggag agtgacatggctctggccatgaaccgctacatcggcaactccatcctgccactactgatc aagcactccaagttctacaacgaggccgaaaactacgccagtctcttggacgccaccctg cacacggtctatcggctgtccaagaaccgtatgctaaccaagggacagcgtgaggccgtc tccgatttcctggtggccctcacgtcccaaatgcaacctgccatgctgctcaagctcctg cgcaagttgactgtggatgtgtccaagctatccgagtacaccaccgtggcactccggctt ctcaccctgcacttcgatcgctgcgccaagtactatggctcaactcaaggccagggctcc tatggagcctcatcggacgaggagaagcgcctgacgatgctgctgttctcgaacattttt gactcgctcagcaatatggactatgacccggaactgttcggtaaagccctgccctgcctg atcgccatcggctgtgccctgccgcccgactacagtctgtccaagaacacggacgaggac tattatggccgccagatgggcgctcccgaccagccgcagtatatgccaaatcccattgac accaccaacgtccacctggacaacgaccttaactcgctggtccagaagttcagtgagcac taccacgacgcctgggccagcaggaggctggagggttcctggacctatggagagatccga tccgacaatgatcgcaaacatccgcgtctcaagccctacaacatgctcagcgaatacgaa cgtgagcgctatcgggatcctgtacgggaatgcttgaagggtctgttggctattggttgg actgtggagcactcggaagtggaggtgcctctcaaccatcgtggatcgacgcgtcgccag tcgaagccccagattcacgatttccagaacgaaggcagcccattcaactacaatccccat ccggtggacatgagcaacctcacgctcagcagggagatgcagaacatggccgagcgcctg gcggagaactcccacgacatctgggccaagaagaagaacgaggagctcaacggctgtggc ggagtcatccacccacaactggtgccctacgatctcctgaccgacaaggagaagaagaag gatcgcgagcgttcgcaggagttcctgaagtacatgcagtaccagggctacaagctgcac aaaccatctaagggcggtgccgtggaagagggtggagccacccaagctgccgtggagctg cgcttctcatactcactgctggagaagctcatccaatacctggacagagccaccatcaac atgaagctgctgaagccatcgaccactttcagtcggcgctcgtccttcaagacagccaca cgtgacataaagttcttctcgaaggtggtgctgcccctgatggagaaatacttctccacc cacaggaactacttcatcgccattgccacggcgacgaacaacattggagctgcctccctt aaggagaaggagatggtggcctcgatcttctgcaagctggccgccttgctgcgcaatcgt ctaagtgcctttggaccagatgtccgcatcacagtgcgctgtcttcaggtcctagtaaag ggcatcgatgcccgcaccctgaccaagaactgccccgagttcatccgcacatcgatgttg acgttcttcaaccaaacctccgatgatctgggcaacacgattctcaatctccaggacggc aagtacagtcacttgcgaggaacgcatctgaagacatcaacgtccctgggatatgtcaat caggtggtgctgccggttctgacggccatgtttgatcacctggcagcctgtgactacgga agcgaccttctattagatgagatccaggtggcctcctacaaaatccttgctgccctctat catctgggcacggatgccacactgacgcatgaccgcaagtatctgaagacggagatcgag aggcatcgtcccgccttgggatcgtgtctgggagcctacagctcctgcttcccagtcgca ttcttggagccgcatctcaacaagcacaaccagtactcgctgcttaaccgaatcgcagat cattcgctggaggcgcaggacatcatggtgaagatggagagctgcatgcccaatttagag accattctctctgaggtggaccagttcgtggagtccgacaagacctacaacgatgcaccg cacatcatagatgtgatcctgccattgctctgcgcttatctgcccttctggtggtcgcag ggtcctgacaacgtcagtcccaccagtggcaaccacgtgaccatggtcaccgccgaccac atgaatccgctgctgcgcaatgtcctgaagatgatcaagaagaacatcggcaacgacaac gccccctggatgactcgcatcgctgcctacacccagcagattatcatcaacacgtcggag gagctgctcaaggatccgttcctgccattggcggagcgggtgaagaagcgcacggagaat atgctccacaaggaggacagcatgcggggcttcatcaagtccgccacggacgacacctcg caggtggagacgcaactgcaggaggactggaacctgctggtgcgagacatctactccttc tacccgctgctcatcaagtacgtggacttgcagcgtaaccactggctgaaggacaacatc cccgaggccgaggagctgtacaaccacgtcgcggagatattcaacatctggtcgaagagc cagtacttcctcaaagaggagcagaactttatctcagccaacgagatcgacaacatggcc cttatcatgccaacggccacgaggagatcggccatttccgaaggtgttcccgccgtgggt ggcaaggtcaagaagaagaagaagaaccgggacaagaaacgcgacaaggacaaggaggtg caggccagtctgatggtggcctgcctgaagcgtctcctgcctgtgggtctcaatctgttc gccggtcgggagcaggagctggtgcagcactgcaaggatcgctacctgaagaagatgccc gagtacgatgtgatcgagtttgcccgcaaccagttgaccctgccagataaactggatccc tccgacgagatgtcctggcagcattatctgtactcgaagttgggcaagacggaggagccg gtggatgagcaggcattggaaaaggccaatgtgaacgccaatgagaagggcaaggacaag accacagagacggtggaccgtattgtggccatggccaaggttttgtttggtctgcacatg atcgaccatccacaacagcagagcaaaaatgtctacaggagcgttgtgtcgatccaaagg aagcgtgccgtaatcgcatgcttccgtcagacatcgctacattctctacccagacatcgt gcctgcaacatctttgcccgctcctactacgagcaatggctgcaggaggagaacgtcggc caggaggttatggtcgaggatcttacccagaccttcgaggactctgagaagtccaagaag gacgaagaggagacagacagcaagccggatccattaacccaattggttaccaccttctgt cgcggtgccatgacggagcgcagtggagccctccaggaggacttgctctacatgtcgtat gcccagattgctgccaagtcctgcggcgaggaggaggaggagggcggcgacgaggagggc ggtgagggaggcgaagagggcgaaggcaccagcatccatgaacaagagatggaaaagcag aaactgctcttccatcaggcacgtctctccaatcgtggtgttgccgaaatggtgctgttg cacatttccgcctccaaaggtataccttcggagatggtaatgacgacactcaatctcggc atcgccatcctgagaggcggcaacatcgacatccaaatgggcatgctgaaccatctgaag gagaagaaggacgtgggtttcttcacctctatcgctggtctgatgaactcgtgcagtgtc cttgatctcgacgcctttgagcgaaacaccaaagcagagggtcttggtgtaggttccgag ggcgccgcgggcgagaagaacatgcacgacgccgagttcacctgtgcgctgttccggttc atccagctgacctgtgaaggtcacaatttggagtggcaaaactatttgaggactcaggcc ggaaacacgacaaccgtgaacgtggtcatctgcactgtggattatcttctccgactccaa gagtccattatggacttttactggcactactccagcaaggagatcatcgaccccgccggc aaagccaacttcttcaaggccatcggagtggccagccaagttttcaacaccctcactgag gtcatccagggtccctgtaccctcaatcaacaggctttggcgcactccaggttgtgggat gcggttggaggattcctattcctgttctcgcacatgcaggacaagttgtcgaagcactcc agtcaggtggacctgcttaaggagctgctgaatctgcagaaggacatgatcacgatgatg ctttccatgctggaaggaaatgttgttaatggcaccattggtaagcagatggtggatact ctggtggagtccgcctccaatgtggagttgattcttaagtactttgatatgttcctgaaa ctggctgacttgattgagtcgccaagcttccacgagatcgacatgaagaacgagggctgg gttacgcccaaggactttagggagaagatggagcaatccaaaaactacacaccggaagaa atggatttccttttggcctgctgtgagcgaaaccacgagggcaagatcgactaccgagcc ttcgtggagcgcttccacgaaccatcaaaggagatcggtttcaacctggctgtgctgctg accaacctcagcgaacacatgcccaatgagccgcgtctggcccgtttcctggaaacggct ggctccgtgctcaactacttcgagccgttcctgggacgcattgagatcctgggtagctcg aagcgcatcgagcgtgtctacttcgaaatcaaggattccaacattgaacagtgggagaaa ccgcagatccgagagtccaagcgcgccttcttctactccatcgtcaccgagggcggcgac aaggagaagcttgaggcttttgtcaacttctgcgaggacgccatctttgagatgacccat gcctcgggcctgatggccaccgatgacggtggcggcaacgtgaagcgggacacggcatac agttcctacatgagcgaagaggaggaggagcgggcagcccgcgatcccatccgacgcacc atcaccgccgtcaaggagggcctcaagttcggagtgcacatgctgagtcctgcgaacatc aagcaccagatcggcgtgatgcagaccaagtccatcccagaactcatcgttggcttcttc aagataatcttctacattttctactacaccggctacgcccacttctgtgtggtgcgctac atatttggaatcctgttgaaccttatgcgtggacctgctcccgagcaggaggaggaacca gtggtggaggaggagacgtttggaagagcactcccgccgttgccgctggaggagccaccg ggtacggtgcaagccttcggcctggacatcaacaaggaagaaaacggcatgtacaaggtg gtggtgcacgaatccccggccaactcctccatggaggagggcggcgagtcgagccctgag gatggagcagctcccgctggagagttggtggaaggagaacctcaccaggaacccatatcg attgtggacttgctgggtggagaggcggcgaagaaggcggcccaggagcgacaggaagcc caaaaggctcaggaagcggccatggcctcgatcgaggcggaggccaagaagtcatcatcg gcgccgcaggagactcccgccgttcaccaaatcgacttctcgcagtacacccaccgagct gtcagcttcctggccaggaacttctacaacctcaagtatgtggccctggtgctggccttc agcatcaatttcatgctgctcttctacaaggtcaccactctcgtggaggagtcggatggg tctggtgaggaggagctcattctgggctccggctctggaggtggcgctgacattacggga tctggattcggtggaggttcgggagatggcgggtcaggcgacggtgaaatcgaagacgac gttccggaactggtgcatgtggacgaggacttcttctatatggaacatgtgctgcgtata gcagccatgctgcactccctcgtctcgctggccatgctgatcgcctactaccacctcaag gtgccactggccatcttcaagcgcgaaaaggagattgcccgtcggctggagttcgatggt ctcttcattgccgagcagccggaggacgacgactttaagtcacactgggacaagttagtg atctcggtcaagagcttcccggtcaactactgggacaagttcgtgaagaagaaggtgcgc cagaagtacagcgagacctacgacttcgactcgatctcaaacttgttgggcatggagaag agcgcgtttgccgcccaggagagcgaggagactggcatcttcaagtacatcatgaacatc gattggcgctaccaggtgtggaaggccggagtgaccttcacggacaacgctttcctctac tcgctgtggtactttagcttctcggtgatgggcaacttcaacaacttcttctttgccgca catctgctcgacgtggccgttggattcaagaccctgcgcaccatcctgcagtcggtaacc cacaacggaaagcaactggtgctgaccgtgatgctgctcaccatcatcgtgtacatttac acggtgatcgcgttcaacttcttccgcaagttctacatccaggaggaggacgaggaggtg gacaagaagtgccacgacatgcttacctgcttcgtcttccatttgtacaagggtgttaga gctggtggaggcatcggagacgagatcggtgatccagatggagacgattacgaagtgtac cgcatcatcttcgacattacgttcttcttcttcgtcatcattatcctgctggccatcatc cagggtttgatcattgacgccttcggagagctccgtgaccaactggagtcggtgaaggac aacatggagtccaattgcttcatatgcggaatgggcaaggacttctttgatatagtaccg cacggcttcgacacgcacgtccagaaggagcacaacctggccaactacatgttcttcctg atgcatttgattaacaagccggacacggagtacaccggccaggagacgtacgtgtggaac atgtaccagcagcgtagctgggacttcttcccagtgggagactgcttccgcaaacagtac gaggatgagttatccggcggaggtggtggtggttag

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