Desulfotomaculum nigrificans: Desca_0276
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Entry
Desca_0276 CDS
T01498
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
dca
Desulfotomaculum nigrificans
Pathway
dca00290
Valine, leucine and isoleucine biosynthesis
dca00620
Pyruvate metabolism
dca01100
Metabolic pathways
dca01110
Biosynthesis of secondary metabolites
dca01210
2-Oxocarboxylic acid metabolism
dca01230
Biosynthesis of amino acids
Module
dca_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
dca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Desca_0276
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Desca_0276
Enzymes [BR:
dca01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Desca_0276
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SSDB
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
URO-D
Motif
Other DBs
NCBI-ProteinID:
AEF93180
UniProt:
F6B5V7
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All DBs
Position
287900..289501
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AA seq
533 aa
AA seq
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MLGDLTPTIKIYDTTLRDGTQGEGVSFSAEDKVKIALRLDEMGFHYIEGGWPGSNPKDME
FFELIKQYPLKQAVVAAFGSTCRPGVPAHQDTNLKRLVESGVKLATIFGKAWDFHVTKAL
NTTLEENLRMVRDSVAYLKSQGLKVFFDAEHFFDGFKANPDYALAVLQAAAGAGADAVVL
CDTNGGSLPFEVQQAVSRVVRQLPGVPVGIHAHNDGELAVANTIMAVQAGATQVQGTVNG
LGERCGNANLCSVIPNLAFKLGYQTIPRENLVYLTELSRFVYEVANLNPVANQPFVGESA
FAHKGGIHVSALMKETGTYEHLAPELVGNQRRVLMSELSGLSNLLYKYKELHLDKNSPEG
RQVLEQLKNMEHRGYQFEAAEGSLELMLRKAVNGYREPFQLESMRLILEMREQQPIYSEA
VIKLRVGEELVHTAAEGNGPVNALDNALRKALETIYPRVADLRLLDYKVRVLEEKAGTEA
LVRVLIETGDGKKTWGTVGVSTNIIEASWQALADSMAYGLLEEQKLTVTNTKK
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
ttgcttggggatttaacaccgaccatcaaaatctatgacaccaccctgcgggacggcacc
cagggcgaaggggttagtttttccgctgaggataaagttaaaattgccctgcggttggat
gaaatgggctttcactatattgaaggcggctggcccggttctaaccccaaggatatggag
ttttttgaactgataaagcagtaccccttaaaacaggccgtggttgctgcctttggcagc
acctgccgccccggtgtgccggcccatcaggacactaaccttaaacgtctggttgaatcc
ggcgttaaactggccaccatcttcggcaaggcctgggatttccatgtaaccaaagccctt
aataccaccctggaagagaacctgcgcatggtgagggattcagttgcctacctgaaaagc
cagggactaaaggtgttctttgatgcggagcacttctttgacggttttaaggccaacccc
gattatgccctggcagtgttgcaagcggcagccggtgccggggccgatgcagtggtactc
tgcgataccaacggtggcagtctgccctttgaagtacagcaggccgtaagccgggtagtg
cggcaattgccgggagtaccggtgggtattcatgcccataacgacggtgaattggcggtg
gccaataccattatggccgtacaggccggggccacccaggtgcagggaacggtaaacggc
ttaggcgagcggtgtggtaatgccaacctttgctcggttattcccaacctggcttttaaa
ctgggctatcaaaccataccccgggaaaacctggtctacctgacggaattgtcccgtttt
gtttatgaagtggccaacttaaatccggtggctaaccaaccctttgtgggagaaagtgcc
tttgctcataaggggggcatccatgtcagtgccctgatgaaagagaccggtacctatgaa
cacctggccccggaactggtgggcaaccagcgccgggtactgatgtccgaactgtccggc
ctgtccaacctgctgtataaatataaagagttacacctggacaaaaacagccccgaagga
cggcaggtgctggaacagctgaaaaatatggagcaccggggctaccagtttgaagcggcg
gaaggctccctggagctgatgctgagaaaagcggtaaacggctaccgggaaccttttcaa
ctggagagcatgcggctgattttggagatgcgggaacagcagcccatctactcagaagca
gtcattaagctgagagtaggcgaggaactggtgcataccgctgctgaaggcaacggcccg
gtcaacgctttagataacgctctgcgcaaagccctggaaaccatttatccccgggtggct
gacctgcggctgctggattacaaagttcgggtactggaagaaaaagcaggtactgaggct
ttggttcgggttttaattgaaacaggtgacggtaagaaaacctggggcacagtgggtgtg
tcaactaatattatcgaagccagctggcaggccctggctgacagtatggcctatggtctg
ctggaggagcagaagcttaccgtaaccaatactaaaaaataa
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