Desulfotomaculum nigrificans: Desca_2346
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Entry
Desca_2346 CDS
T01498
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
dca
Desulfotomaculum nigrificans
Pathway
dca00300
Lysine biosynthesis
dca00550
Peptidoglycan biosynthesis
dca01100
Metabolic pathways
dca01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
dca00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Desca_2346
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Desca_2346
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Desca_2346
Enzymes [BR:
dca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Desca_2346
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEF95181
UniProt:
F6B3F0
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All DBs
Position
complement(2461731..2463101)
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AA seq
456 aa
AA seq
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MLTYTIKEIAAVTGGTIIQGNPAAEVNGLCTDSRRAKNGDIFVAMRGRQVDGHDFALKAI
EQGATALLVTKTVTVPPQVAVIKVSDTIQALQQLAAHNRSRLNIPVVAVTGSNGKTSTKD
MIAAVLNTRYKTLKTQGNYNNELGLPLTLLALDQTHQAAVVEMGMRGFGEIDLLARLAKP
TGAVITNIGEAHLELLGSVQNIAAAKAEVLDHIGAEGFAILNGDSPELRNQVSRCQGQVW
FYSINGQTDLVARNVRVEGRGVRYDLSYPGGTGEIYLPIPGSHNVMNSMAAVGVGLRLGI
PFTDIVRGLAQVELTGMRLEIIKANNMTVINDVYNANPSSTKAALKVLAEVAPGRKIAVL
GNMYELGALAESGHREVGEAAALRGIAQLVTVGDLARFTAQGAIKGGLPGDRVHHCDNNK
LAIEVLRQVMQPGDTILVKGSRSMHMEEIVQALVNN
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgctgacttataccataaaagaaattgccgcagttaccggggggacgattatccagggt
aatccggcagccgaggttaacggactttgcaccgacagccgccgggctaagaacggggat
atatttgtagccatgcggggccggcaggtggacggtcatgattttgccctgaaggccata
gagcagggggccaccgcactgctggtgacaaaaacagtaaccgtacccccgcaggtggct
gtcatcaaggtatccgataccatccaggccttacagcaactggccgcccacaaccggagc
cggctcaacatcccggtggtggcggtaaccggcagtaacggcaaaacctccactaaagat
atgatcgcagcggtattaaatacccgctacaaaaccctaaagacccagggcaactataat
aatgaattgggtcttcccttgaccttattggctctggatcaaacccaccaggcagcggtg
gtggagatgggcatgcgggggttcggggaaatcgacttgttggcccggctggccaaaccc
accggagccgttattactaacattggtgaggctcacctggaactcttagggtcagtgcag
aacattgctgccgccaaggcagaggttttagatcacatcggagcggaggggtttgccatt
cttaacggtgatagccccgagttaagaaatcaggtttcccgttgccagggccaggtctgg
ttttactccattaacggtcaaacagatttggtggccaggaatgtgcgagtggaaggccgg
ggagttaggtatgacctatcataccccggtgggacaggggaaatatacctgcccattccc
ggcagtcataacgtaatgaatagtatggccgccgtgggggtggggttaaggttagggata
ccctttaccgacattgtccggggattagcccaggtggagctcaccggcatgcggctggaa
attattaaagccaataacatgaccgttattaacgatgtctataatgccaacccctcttcc
accaaagccgctttaaaagtattagcagaagtagccccgggaagaaagattgccgtactt
gggaatatgtatgaactgggggcgttagccgagtccgggcaccgtgaggtgggagaagcg
gcggccctaagaggtatcgcccagttggtgacagtgggtgacctggcccgatttacggcc
cagggcgctattaaagggggtctgcccggagacagggtacaccattgtgataataataag
ctagccattgaagttttacggcaagttatgcaacccggtgatacaattctggttaagggt
tcccggagtatgcacatggaagagatagtccaggcgctggtcaataactaa
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