KEGG   Dermochelys coriacea (leatherback sea turtle): 119840995
Entry
119840995         CDS       T09064                                 
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
dcc  Dermochelys coriacea (leatherback sea turtle)
Pathway
dcc00562  Inositol phosphate metabolism
dcc01100  Metabolic pathways
dcc04012  ErbB signaling pathway
dcc04020  Calcium signaling pathway
dcc04070  Phosphatidylinositol signaling system
dcc04370  VEGF signaling pathway
dcc04625  C-type lectin receptor signaling pathway
Module
dcc_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:dcc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    119840995 (PLCG2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    119840995 (PLCG2)
   04370 VEGF signaling pathway
    119840995 (PLCG2)
   04020 Calcium signaling pathway
    119840995 (PLCG2)
   04070 Phosphatidylinositol signaling system
    119840995 (PLCG2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    119840995 (PLCG2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dcc04131]
    119840995 (PLCG2)
Enzymes [BR:dcc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     119840995 (PLCG2)
Membrane trafficking [BR:dcc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    119840995 (PLCG2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    119840995 (PLCG2)
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 SH3_1 SH3_9 PH SH2_1 PH_12 SH3_2 EF-hand_PLCG1 DUF5717 EF-hand_like PH_14 GDPD
Other DBs
NCBI-GeneID: 119840995
NCBI-ProteinID: XP_038223742
LinkDB
Position
12:33619644..33711897
AA seq 1265 aa
MSRKSTDYGMLPEYERSQIKRTLELGTVMTVFSLKKFTPERRTIQVIMETRQVAWSKTAD
KIEGFLDLREIKEIRPGKNAKDFERGKATQNKEHCFTIFYGAQFVLNTLSLAADSKDDAD
KWLCGLNILHQEVMNASTPAITESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVGSV
KYLKDKFAEIGAPKEELSFEQFHVFYKKIMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQESWAQDLSKVRERMTKFIDDTMRETTEPFLFVDEFLTYLFSKENS
IWDDKYDAVDAQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSEFPVILSIEEHCSVEQQRHMAKV
FKELFGNQLLMKPIEVSADQLPSPTQLKEKFIIKHKKLGPKGDVDTNPEDKKEEKKQQGE
LYMWDMIEQTWTRHYCVIADEKLSFSDDIEENTDDDSSEEVEHTELHCSEKWFHGKMKEG
RTTAERLIQEYCAEMGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSNSEGDTMKY
YLTDHLTFDSIYDLVQHYKEAHLRCAEFELRLTDAVPNPKPHETKDWYYHNLSRGEAEDM
LMRIPRDGAFLIRKRDEPNSFAMTFRAEGKVKHCRIQQEGRRFLLGTSADFESLVELVTY
YKKHKLYRKMKLRYPVTEELLERYSTEKDINALYDVKMYVEPNEITPSMPQRTVKAIYDY
KAKRSDELSFCRGALIHNVTKETGGWWKGDYGEKVQRYFPSNYVEDVSTDNLADFENQII
EDNPLGSLCRGILVLNTYKVEKMLQGKYGKTYVFILEPKNPKDPPVEFATDTVEELFEWF
QGIREITQKTAEEENWRKYWEKNQLIAIELSDLVIYCKPTSKSKDSLENPDFREVRSFVE
NKAESVVRQKPGELLKYNQKGLTRVYPKGQRVDSSNYDPFRLWFCGAQMVSLNFQTPDKY
MQINHALFSLNGRTGYILQPESMRNEDYDPMPSESKRKLQMLLTVRVLGARHLPKPGRSI
ACPFVEVEICGAKCDNSKFKTTVVNDNGLNPVWVPCPEQVKFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATFPIKGIKSGFRSVPLKNGYSEDTELASLLVFCEMQQVLESEEELYSSC
RQLRKRQAELNNQLFLYDTHQNLRNPNRDALLKEFSVNENQLQMYQETCSRRLKEKKVSN
SKFYS
NT seq 3798 nt   +upstreamnt  +downstreamnt
atgtccaggaagagcacagactatggaatgctgccggagtatgagaggagccagatcaaa
aggactctggagctgggaacagttatgacagtgttcagtctcaagaagtttactccagaa
aggaggaccatccaagtcataatggaaaccaggcaggtggcctggagcaagacagctgac
aagattgaaggtttcttggatctgagggaaataaaggaaattcgccctgggaaaaatgca
aaggattttgagcgcgggaaagcaacacagaataaagagcattgctttactattttttat
ggtgcccagtttgttctcaacaccttaagcttagcagctgattccaaagatgatgctgat
aaatggctgtgtggcttgaatatcttgcatcaagaggttatgaatgcttccacacctgca
atcacagagagctggctgagaaagcagatctactccgttgaccagactagaaggaacagt
atcagccttagagaactgaagaccatacttcctttaataaatttcaaagtaggcagcgtg
aaatacttgaaggataaatttgcggaaataggagctcccaaggaagaacttagcttcgaa
caatttcacgtgttctacaagaaaattatgtttgaacagcagaaatcgattcttgatgaa
ttcaaaaaggattcttcggtgttcattcttggaaatactgaccgtccagatgcttccgca
gttcatttgcatgacttccagagatttttgctacacgagcagcaggagtcttgggcacag
gatctcagtaaagtccgagaacgaatgacaaagtttatagatgacactatgagagaaact
actgagcccttcctcttcgtagatgagtttctcacttaccttttctcaaaagaaaacagt
atttgggatgataaatatgatgcagtagatgctcaggatatgaataaccctttgtcccac
tactggatttcttcctctcacaacacatacctcacaggagaccagcttcgaagtgaatct
tccacagaagcttatatcaggtgccttcgaatgggatgccgatgtattgagctggattgc
tgggatggtcctgacgggaagccgatcatttatcacggatggacaaggacaacaaaaatc
aaattcgatgatgtggtacaggcaatcaaggatcatgcatttgtcacatctgagttccca
gtgatcctgtcgattgaagagcactgcagtgtggaacagcagcgccacatggccaaagta
ttcaaggagttgtttgggaatcaactcctaatgaagccaatcgaagtcagtgcagatcag
ctgccatcgccaacccagctgaaagaaaaattcatcatcaagcataaaaaattgggacca
aagggagacgtagatacgaacccagaagacaagaaagaggagaaaaagcaacaaggagaa
ctctacatgtgggatatgatagaacagacatggactcggcactattgtgttatagcagat
gaaaagctctcattcagtgatgatatagaagagaacactgatgacgattcatcagaggag
gtggaacatactgagctgcactgcagcgagaaatggttccatgggaaaatgaaagagggg
agaacaactgctgagaggctgatacaggaatattgtgctgaaatgggtggcaaggatgga
acgttcctagttagggaaagcgaaactttccctaatgattacaccctgtcattctggagg
tcaggtagggtccagcattgccgtatccgttctaatagtgaaggtgataccatgaaatat
tacctgaccgaccacctcacctttgatagtatttatgatctcgttcaacactacaaggaa
gcccatttgcgttgtgctgagtttgagctgcgtctgactgatgctgtgcctaaccccaaa
cctcatgaaactaaagactggtactatcataacctgagtcgaggagaagcagaagacatg
ttgatgcgaattcctcgagatggagcgtttctgattagaaagagagatgagcccaactca
tttgccatgacattcagagctgaggggaaagtgaagcactgcagaattcaacaagaaggc
cgccgctttttgctgggcacctctgccgattttgaaagcttagtcgaactggtgacctac
tacaaaaagcacaagttgtataggaaaatgaaactgcgttaccctgtgactgaggaactg
ctagagcgctacagcacggagaaagatattaatgcgctctatgatgtcaagatgtatgtg
gagcctaacgaaataaccccatcaatgcctcagagaacagtgaaagccatatatgactat
aaagctaagagaagtgatgaactgagcttctgcagaggggccctaattcataatgtcaca
aaggagacaggaggctggtggaaaggagactatggagaaaaagtccaacgctattttcca
tcgaattacgttgaagacgtgtcaactgataacttagcagactttgaaaaccagattatt
gaggacaaccccttaggatctctgtgtcgtggcatactggtcctcaatacatacaaagtc
gagaaaatgttgcaagggaagtatggcaagacttatgttttcatactggaacccaagaat
ccaaaagaccctcctgttgaatttgcaacagatacggtggaagagctgtttgaatggttc
caaggcatcagggaaatcacacagaaaactgcagaagaggagaattggaggaagtactgg
gaaaagaatcaattaattgccattgaattatctgacttagtaatctactgcaaacctaca
agcaaatccaaggacagtttagaaaatcctgatttcagagaagtccgttcttttgtggaa
aacaaggctgaaagtgttgtcaggcagaagcctggtgagctgttgaaatacaaccaaaag
ggactgacacgggtctatcctaaaggacagagggttgactcatctaactatgacccattt
cgcctctggttttgtggcgcccagatggtgtctcttaatttccagacgccagataaatac
atgcaaataaaccatgccttgttttcacttaatggacggactggatacattctgcagcca
gaaagcatgcgaaatgaggactatgacccaatgccaagtgaatcaaagagaaaactgcag
atgcttttgacagttagggttttaggtgctcgccatctgcctaaacccggcagaagcatt
gcctgtccatttgtagaggtggagatttgtggggccaaatgtgataatagcaagttcaag
acaacagttgtgaacgacaatggccttaacccagtttgggtaccctgtccagagcaagtg
aagtttgaaatttatgatcctaacttagcgtttctgcgcttcgttgtttatgaggaggat
atgttcagtgaccccaacttcttagcacatgccacttttcccatcaaaggaatcaaatca
ggttttaggtcagtacctctcaaaaatggttacagtgaagatacagagctggcttccctt
ctggttttctgtgaaatgcagcaagttctggaaagcgaagaggagctttattcatcgtgt
cggcagcttcggaagcgccaagcagaactgaacaaccagctcttcctgtatgacacccac
cagaatttaaggaaccctaacagagatgccttactaaaagaattcagtgtgaatgagaac
caattacaaatgtaccaagagacatgcagcaggagattaaaggagaagaaagtcagtaac
agcaaattctactcctag

DBGET integrated database retrieval system