Dermochelys coriacea (leatherback sea turtle): 119852496
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Entry
119852496 CDS
T09064
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
dcc
Dermochelys coriacea (leatherback sea turtle)
Pathway
dcc00270
Cysteine and methionine metabolism
dcc00480
Glutathione metabolism
dcc01100
Metabolic pathways
dcc01240
Biosynthesis of cofactors
dcc04216
Ferroptosis
Module
dcc_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
dcc00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
119852496 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
119852496 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
119852496 (GCLC)
Enzymes [BR:
dcc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
119852496 (GCLC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
119852496
NCBI-ProteinID:
XP_038249612
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Position
3
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRHAEHVRRHGILQFLHIYRAVAERHKDVLKWGDEVEYMLVAFDH
EHKKVRLSLTGEEVLHTLQEKGERVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRREAASVLKEDEALCTVTSFPRLGCPGFTLPECEPMPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPQDDGEAAKAAKPDHVYMD
AMGFGMGNCCLQVTFQACSISEARCLYDQLATICPIVMALSAAAPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEHLV
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGYGPAQIGKETDAEEYTLMSIDTIINGKDGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNY
SLIRKCNQIAQEQAECPELLGVGFNKIKHSGNKTSSS
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcaaggctccccgctgagctgggaggagacgcagcggcacgcggag
cacgtgcgccggcacggcatcctccagttcctgcacatctaccgcgccgtggccgagcgc
cacaaggacgtgctcaaatggggggacgaggtggaatatatgttggtagcttttgatcat
gaacataagaaagtacgtttgtcactaactggagaagaagttcttcatacactgcaagag
aagggggaaagagtaaatcccaaccacccaacactttggcgtccagaatatggaagctat
atgattgaagggacacctgggcagccatatggaggaaccatgtctgaatttaacactgta
caagacaacatgaggaaacgacggcgggaggctgcttctgtgttgaaagaagatgaggct
ctttgtactgtgacatcatttccaagattaggatgtccaggatttacgctaccggaatgt
gagccaatgccagtagaaggaggtgcttcaaagtctctcttctttccagatgaagccatc
aacaaacatcctagatttagtactctgacaagaaacattcgacaccgaagaggagagaaa
gtagtgataaacgtaccaatatttaaagataagaatactccatcaccatttatagaaaca
tttcctcaggacgatggagaagcagcaaaagcagctaaaccagaccatgtatatatggat
gccatgggttttggaatgggcaactgctgccttcaggtaacattccaggcttgcagcatt
tccgaagcaagatgcctttatgatcagctagccacaatctgtcctatcgtgatggcatta
agtgctgcagctcccttctacagaggctacgtgtcggatattgactgtcgctggggagta
atatctgcatcagtagatgaccgaacacgagaggagagaggattggagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgaaaaatacaatgacattgatttgacaatagataaagaaatctacgagcatctagta
aaggaaggcattgatcatcttttggcacaacatattgcacacttatttattcgagacccg
ttgactttgttcgaagagaaaatacatctagatgatgcaaatgaatctgatcattttgag
aatattcagtccacaaactggcagactatgagatttaaaccacctcctccgaattcagat
attggatggagagtagaatttaggcccatggaggttcagttaacagactttgaaaactct
gcgtatgttgtttttgtggtattgctaaccagagtgattctgtcatataaactggatttt
ctcattcctttgtccaaggttgatgaaaatatgaaggtagcccagaaacgagatgctgtt
cggcagggaatgttttatttcagaaaagatatttgtaaaggtggaaatgctgtggtagat
ggatatggcccagcacagattgggaaagagacagatgcagaagagtacaccttgatgagc
atagacacaatcatcaatgggaaggatggtgtctttcctggcttaatcccaattctaaac
tcttacctcgaaaacatggaagtggatgtggacacaagatgcaccattttgaactacctg
aaattaattaaaaagagagcctctggagaattaatgacagttgctcggtggatgagggag
tttattgcaaaccatcctgactacaagcaagatagtgtgatcactgatgaaatgaattac
agccttattaggaaatgcaaccaaattgcacaagaacaagcggaatgccccgaattactt
ggagtaggatttaacaaaataaaacacagtggaaataaaactagctcttcttaa
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