Dermochelys coriacea (leatherback sea turtle): 119862368
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Entry
119862368 CDS
T09064
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
dcc
Dermochelys coriacea (leatherback sea turtle)
Pathway
dcc03440
Homologous recombination
dcc03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
dcc00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
119862368 (TOP3A)
03460 Fanconi anemia pathway
119862368 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dcc03032
]
119862368 (TOP3A)
03400 DNA repair and recombination proteins [BR:
dcc03400
]
119862368 (TOP3A)
Enzymes [BR:
dcc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
119862368 (TOP3A)
DNA replication proteins [BR:
dcc03032
]
Eukaryotic type
DNA Topoisomerases
119862368 (TOP3A)
DNA repair and recombination proteins [BR:
dcc03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
119862368 (TOP3A)
FA (Fanconi anemia) pathway
119862368 (TOP3A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
Zn_ribbon_GRF_2
Zn_ribbon_recom
Lar_restr_allev
Motif
Other DBs
NCBI-GeneID:
119862368
NCBI-ProteinID:
XP_038274936
LinkDB
All DBs
Position
10:7096167..7113028
Genome browser
AA seq
1019 aa
AA seq
DB search
MNFQARLFARCGVRLLSQSWSLFSQAAEDMTFGKIQKVLCVAEKNDAARGIADILSNSRM
RRREGFSKFNKIYEYDYHMFGQNVTVAMTSVSGHLLAHDFKMPFRKWHSCNPLVLFEAEI
EKYCPENFVDIKKTLEREARQCQALVIWTDCDREGENIGFEIIHVCKAVKPRLQVFRARF
SEITPRAIRGACENLVQPDQNISDAVDVRQELDLRIGAAFTRFQTLRLQKLFPDVLAEQL
ISYGSCQFPTLGFVVERFKAIQAFVPEAFYKIKVTHEHEDGMVDFNWKRNRLFNHTACLV
LYHMCMEDPVATVIEIGSKPKSKWRPLALDTVELEKLASRKLKINAKETMKIAEKLYTQG
YISYPRTETNIFPKDLNLTSLVQQQTQDPNWGAFAQGILDRGGPTPRNGTKSDQAHPPIH
PTKHTCNLQGNEQRLYEFIVRHFLACCSQDAKGQETTVVIDIANERFVAHGLMILARNYL
DVYPYERWSDKVLPVYQRGSRFQPTTVEMVDGETSPPQLLTEADLISLMEKHGIGTDATH
AEHIETIKSRMYVGLTPDQRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEG
KKDKFVVLRQQIEKYQKVFTEAVAKANKLDQALSQYFGEVTALAQQEEIYPAMPVSIRKC
PQCNSDMVLKSKKNGGFYLGCMNYPNCKAAVWFPESVLEVSKDDSVCAVCKPHPVHRLKF
KFKRGSVPPLLPLEFVGCIGGCDEMLREILDLKYLQGPSRPVQSVNPPANYLQVNQSLNR
MASYENGHVRPTTNPGVARAPRAASHPAPAAAENNAVVCNCREEAALLTVRKEGPNQGRQ
FYKCSAGSCNFFLWADQQSDDGNSVTHRSFAAPPDSLGERPPGSFGSLGGGRGLGRYGSN
DFDSGGGGGGTMCKCNQPAITRTVQKEGPNKGRQFHTCPKPREQQCGFFQWVDENVAPGT
ARAFSSNQFRSEGHLRGSGSKAKRPSNLSSEKGPTPKRQRTCGICHQLGHTRKTCPQDH
NT seq
3060 nt
NT seq
+upstream
nt +downstream
nt
atgaactttcaggccaggctttttgcccgctgtggggtcaggttgttgtctcagtcctgg
agtctcttctcccaggctgcagaggatatgacattcggaaagattcagaaggtcctctgt
gtagcagagaaaaatgatgctgccagaggaattgcagatattctctccaatagcagaatg
aggcggagagaagggttttccaaattcaacaagatctatgaatatgactatcatatgttt
ggccagaatgttactgtggcgatgacctctgtttcgggacatttgctggctcatgacttt
aagatgccatttcgcaaatggcatagctgcaacccacttgtactctttgaagctgaaatt
gagaaatactgccctgaaaactttgtggatattaagaaaaccctagaacgagaagcccgg
cagtgccaggctctggtgatctggaccgactgcgatcgagaaggagagaacattggtttt
gagataatccatgtttgcaaagctgtgaagccaagacttcaggtgttccgagcccgcttt
tccgagatcactcctcgtgccataagaggagcctgcgagaatcttgtccaacctgatcag
aacattagcgatgctgtggatgtcagacaggagctggaccttaggataggtgctgcattc
accagattccagaccctaaggctccagaagctctttcccgacgttttagccgagcagttg
atcagctatggtagctgtcagttcccaactctgggatttgtggtagaaagatttaaagcc
atccaggcctttgttcccgaagccttctataaaattaaagtgacccatgaacatgaggac
ggcatggtagacttcaactggaagaggaaccgactctttaaccacacagcatgccttgtc
ctctaccacatgtgtatggaggatccagtggccactgttatcgagattgggagcaaaccg
aagagcaaatggaggcccctggcactagacactgtggaacttgagaagctggcttcccgc
aagctaaaaataaatgccaaagaaactatgaaaatagcagaaaagctctacactcaaggg
tacataagctatccccgaactgagaccaacattttccccaaagacctaaacctcacctct
ttggtacaacagcagacccaagaccccaactggggagcctttgcacaggggattctagac
cggggtgggccaacccctcggaatgggaccaaatccgatcaggctcaccctcccattcac
cccactaaacatacatgtaacctgcaggggaatgaacagcgactatatgagttcattgtg
cgtcactttttggcttgctgctcccaggatgctaagggacaagaaacaactgtggtgatt
gacattgctaatgagcgatttgttgctcatgggctaatgatcctggccagaaactatctg
gatgtctatccttatgagaggtggagtgacaaggttctcccagtgtatcagagggggtct
cgctttcagcccaccacagtggagatggtggatggggagaccagcccaccccaactcctc
acggaagctgatctcatatcactcatggagaaacatggcattgggactgatgccactcac
gccgagcacatcgagaccatcaagtcacggatgtacgtggggcttactccagatcagagg
ttccttccggggcacttgggcatggggctggtagaaggctacgattccatgggctacgag
atgtcaaaacctgaccttcgagctgagctggaggctgatctgaagctgatttgtgagggg
aaaaaggacaaatttgtagtgctgaggcagcagattgagaagtaccagaaagtcttcact
gaagccgtggccaaagccaacaagttggatcaagctttgtctcagtattttggagaagta
acggcacttgcgcagcaagaggagatctatccagcaatgcccgtttccattcggaaatgt
ccacagtgcaacagtgacatggtcctgaagagcaagaagaatggcggcttttatctgggc
tgcatgaactatcctaactgtaaagcagctgtgtggtttcctgaatctgtgctggaagtc
agcaaggatgacagtgtttgcgctgtgtgtaaaccccatccggttcataggctgaaattt
aagttcaagcgaggtagtgtcccacccctgctgccactggaatttgttggctgtattgga
ggttgcgatgagatgttgagagagatcttggacctgaaatatttacaaggaccatccaga
ccggtacagtcagtcaacccgccagctaactacctacaagtcaaccagtcccttaaccgc
atggccagttatgagaatggtcacgtgaggcctaccacaaaccctggtgtagcaagggca
cccagagctgctagtcatccagctcctgctgctgctgagaacaatgcagtggtgtgcaac
tgtagggaggaggcagcattgctcacggtgcgtaaagaagggccaaaccagggcaggcag
ttctataaatgcagtgccggcagctgcaacttcttcctctgggccgatcaacaatcagat
gatggaaacagcgtaacccacaggagctttgctgcaccccctgattccttgggtgagagg
cctccaggaagtttcgggagccttggaggaggaagaggtctgggccgctatggaagcaac
gattttgactcgggaggagggggcggtggcacgatgtgtaagtgcaatcagccggccatc
acacgcaccgttcaaaaggagggacccaataaagggcgtcagttccacacgtgcccaaag
ccgagagagcagcagtgcggcttcttccagtgggtggatgaaaacgtggccccaggaact
gctagagccttctcttcaaaccaattcaggagcgaagggcacttaagagggtcaggaagc
aaagctaaaagaccaagtaatctctcttctgaaaaaggacctactcccaagagacaacgg
acgtgtggcatttgccaccagcttggtcacaccaggaagacatgtcctcaggaccactga
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