Dermochelys coriacea (leatherback sea turtle): 119862368
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Entry
119862368 CDS
T09064
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
dcc
Dermochelys coriacea (leatherback sea turtle)
Pathway
dcc03440
Homologous recombination
dcc03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
dcc00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
119862368 (TOP3A)
03460 Fanconi anemia pathway
119862368 (TOP3A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
dcc03032
]
119862368 (TOP3A)
03400 DNA repair and recombination proteins [BR:
dcc03400
]
119862368 (TOP3A)
Enzymes [BR:
dcc01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
119862368 (TOP3A)
DNA replication proteins [BR:
dcc03032
]
Eukaryotic type
DNA Topoisomerases
119862368 (TOP3A)
DNA repair and recombination proteins [BR:
dcc03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
119862368 (TOP3A)
FA (Fanconi anemia) pathway
119862368 (TOP3A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
Zn_ribbon_GRF_2
Zn_ribbon_recom
Motif
Other DBs
NCBI-GeneID:
119862368
NCBI-ProteinID:
XP_038274936
LinkDB
All DBs
Position
10:7096167..7113028
Genome browser
AA seq
1019 aa
AA seq
DB search
MNFQARLFARCGVRLLSQSWSLFSQAAEDMTFGKIQKVLCVAEKNDAARGIADILSNSRM
RRREGFSKFNKIYEYDYHMFGQNVTVAMTSVSGHLLAHDFKMPFRKWHSCNPLVLFEAEI
EKYCPENFVDIKKTLEREARQCQALVIWTDCDREGENIGFEIIHVCKAVKPRLQVFRARF
SEITPRAIRGACENLVQPDQNISDAVDVRQELDLRIGAAFTRFQTLRLQKLFPDVLAEQL
ISYGSCQFPTLGFVVERFKAIQAFVPEAFYKIKVTHEHEDGMVDFNWKRNRLFNHTACLV
LYHMCMEDPVATVIEIGSKPKSKWRPLALDTVELEKLASRKLKINAKETMKIAEKLYTQG
YISYPRTETNIFPKDLNLTSLVQQQTQDPNWGAFAQGILDRGGPTPRNGTKSDQAHPPIH
PTKHTCNLQGNEQRLYEFIVRHFLACCSQDAKGQETTVVIDIANERFVAHGLMILARNYL
DVYPYERWSDKVLPVYQRGSRFQPTTVEMVDGETSPPQLLTEADLISLMEKHGIGTDATH
AEHIETIKSRMYVGLTPDQRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEG
KKDKFVVLRQQIEKYQKVFTEAVAKANKLDQALSQYFGEVTALAQQEEIYPAMPVSIRKC
PQCNSDMVLKSKKNGGFYLGCMNYPNCKAAVWFPESVLEVSKDDSVCAVCKPHPVHRLKF
KFKRGSVPPLLPLEFVGCIGGCDEMLREILDLKYLQGPSRPVQSVNPPANYLQVNQSLNR
MASYENGHVRPTTNPGVARAPRAASHPAPAAAENNAVVCNCREEAALLTVRKEGPNQGRQ
FYKCSAGSCNFFLWADQQSDDGNSVTHRSFAAPPDSLGERPPGSFGSLGGGRGLGRYGSN
DFDSGGGGGGTMCKCNQPAITRTVQKEGPNKGRQFHTCPKPREQQCGFFQWVDENVAPGT
ARAFSSNQFRSEGHLRGSGSKAKRPSNLSSEKGPTPKRQRTCGICHQLGHTRKTCPQDH
NT seq
3060 nt
NT seq
+upstream
nt +downstream
nt
atgaactttcaggccaggctttttgcccgctgtggggtcaggttgttgtctcagtcctgg
agtctcttctcccaggctgcagaggatatgacattcggaaagattcagaaggtcctctgt
gtagcagagaaaaatgatgctgccagaggaattgcagatattctctccaatagcagaatg
aggcggagagaagggttttccaaattcaacaagatctatgaatatgactatcatatgttt
ggccagaatgttactgtggcgatgacctctgtttcgggacatttgctggctcatgacttt
aagatgccatttcgcaaatggcatagctgcaacccacttgtactctttgaagctgaaatt
gagaaatactgccctgaaaactttgtggatattaagaaaaccctagaacgagaagcccgg
cagtgccaggctctggtgatctggaccgactgcgatcgagaaggagagaacattggtttt
gagataatccatgtttgcaaagctgtgaagccaagacttcaggtgttccgagcccgcttt
tccgagatcactcctcgtgccataagaggagcctgcgagaatcttgtccaacctgatcag
aacattagcgatgctgtggatgtcagacaggagctggaccttaggataggtgctgcattc
accagattccagaccctaaggctccagaagctctttcccgacgttttagccgagcagttg
atcagctatggtagctgtcagttcccaactctgggatttgtggtagaaagatttaaagcc
atccaggcctttgttcccgaagccttctataaaattaaagtgacccatgaacatgaggac
ggcatggtagacttcaactggaagaggaaccgactctttaaccacacagcatgccttgtc
ctctaccacatgtgtatggaggatccagtggccactgttatcgagattgggagcaaaccg
aagagcaaatggaggcccctggcactagacactgtggaacttgagaagctggcttcccgc
aagctaaaaataaatgccaaagaaactatgaaaatagcagaaaagctctacactcaaggg
tacataagctatccccgaactgagaccaacattttccccaaagacctaaacctcacctct
ttggtacaacagcagacccaagaccccaactggggagcctttgcacaggggattctagac
cggggtgggccaacccctcggaatgggaccaaatccgatcaggctcaccctcccattcac
cccactaaacatacatgtaacctgcaggggaatgaacagcgactatatgagttcattgtg
cgtcactttttggcttgctgctcccaggatgctaagggacaagaaacaactgtggtgatt
gacattgctaatgagcgatttgttgctcatgggctaatgatcctggccagaaactatctg
gatgtctatccttatgagaggtggagtgacaaggttctcccagtgtatcagagggggtct
cgctttcagcccaccacagtggagatggtggatggggagaccagcccaccccaactcctc
acggaagctgatctcatatcactcatggagaaacatggcattgggactgatgccactcac
gccgagcacatcgagaccatcaagtcacggatgtacgtggggcttactccagatcagagg
ttccttccggggcacttgggcatggggctggtagaaggctacgattccatgggctacgag
atgtcaaaacctgaccttcgagctgagctggaggctgatctgaagctgatttgtgagggg
aaaaaggacaaatttgtagtgctgaggcagcagattgagaagtaccagaaagtcttcact
gaagccgtggccaaagccaacaagttggatcaagctttgtctcagtattttggagaagta
acggcacttgcgcagcaagaggagatctatccagcaatgcccgtttccattcggaaatgt
ccacagtgcaacagtgacatggtcctgaagagcaagaagaatggcggcttttatctgggc
tgcatgaactatcctaactgtaaagcagctgtgtggtttcctgaatctgtgctggaagtc
agcaaggatgacagtgtttgcgctgtgtgtaaaccccatccggttcataggctgaaattt
aagttcaagcgaggtagtgtcccacccctgctgccactggaatttgttggctgtattgga
ggttgcgatgagatgttgagagagatcttggacctgaaatatttacaaggaccatccaga
ccggtacagtcagtcaacccgccagctaactacctacaagtcaaccagtcccttaaccgc
atggccagttatgagaatggtcacgtgaggcctaccacaaaccctggtgtagcaagggca
cccagagctgctagtcatccagctcctgctgctgctgagaacaatgcagtggtgtgcaac
tgtagggaggaggcagcattgctcacggtgcgtaaagaagggccaaaccagggcaggcag
ttctataaatgcagtgccggcagctgcaacttcttcctctgggccgatcaacaatcagat
gatggaaacagcgtaacccacaggagctttgctgcaccccctgattccttgggtgagagg
cctccaggaagtttcgggagccttggaggaggaagaggtctgggccgctatggaagcaac
gattttgactcgggaggagggggcggtggcacgatgtgtaagtgcaatcagccggccatc
acacgcaccgttcaaaaggagggacccaataaagggcgtcagttccacacgtgcccaaag
ccgagagagcagcagtgcggcttcttccagtgggtggatgaaaacgtggccccaggaact
gctagagccttctcttcaaaccaattcaggagcgaagggcacttaagagggtcaggaagc
aaagctaaaagaccaagtaatctctcttctgaaaaaggacctactcccaagagacaacgg
acgtgtggcatttgccaccagcttggtcacaccaggaagacatgtcctcaggaccactga
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