KEGG   Dictyostelium discoideum (cellular slime mold): DDB_G0277221
Entry
DDB_G0277221      CDS       T00245                                 
Symbol
chcA
Name
(RefSeq) clathrin heavy chain
  KO
K04646  clathrin heavy chain
Organism
ddi  Dictyostelium discoideum (cellular slime mold)
Pathway
ddi04142  Lysosome
ddi04144  Endocytosis
ddi05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:ddi00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    DDB_G0277221 (chcA)
   04142 Lysosome
    DDB_G0277221 (chcA)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    DDB_G0277221 (chcA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ddi04131]
    DDB_G0277221 (chcA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ddi04147]
    DDB_G0277221 (chcA)
Membrane trafficking [BR:ddi04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Clathrin
    DDB_G0277221 (chcA)
Exosome [BR:ddi04147]
 Exosomal proteins
  Proteins found in most exosomes
   DDB_G0277221 (chcA)
SSDB
Motif
Pfam: Clathrin Clathrin_propel Clathrin_H_link Clathrin-link TPR_COPA_B SirC_C HCNGP
Other DBs
NCBI-GeneID: 8620910
NCBI-ProteinID: XP_642717
dictyBase: DDB_G0277221
UniProt: P25870
LinkDB
Position
2:7717198..7722630
AA seq 1694 aa
MTNLPIRFQEVLQLTNLGIGSNSIGFSTLTMESEKYICIRETTPDDKNNVVIIDTDNPSQ
ILRKQMKTDAAIMNPKEPILALKIGQVLQLISIEQKMQLKSCQMQEPLEFWKWISPNTLA
LVTATSVFHWTKEGNSDPVKVFDRHPDLQNTEIINYRSDSTQNWLVLVAIHQRDGRVVGR
IQLYSVEKQISQSIEGHAACFANYIVPGATRPSTLFAISSRTQNASKILVLEVSKGDGPN
FQKRASDVFYPPEIGASDFPVAMQVSEKYEVIYMVTKLGYIHLFDLGTANLIYRNRISNE
NIFVTAFEESTNGIIAVNRKGQVLSVSIDDKNIIPYICNTLNNLELAISMACKNNLPGAE
GLLTTQFERYFQQGQYKEAAKVAADSPGSILRNLQTIQKFQSIPPIPDQPSALLQYFGML
LEKGKLNKVESLELVRPVLAQGKKPILEKWLTEDKLECSEQLGDEVRPHDRKLALSIYYR
ANASDKVITLFAETGEFDKIIAYCKKFNYKPDFMFLLQRMANANPMGAADFAVKLVKEEG
GPYIDANQVVELFSARNMIQETSNFLFAILDGDRPQDANLQTKLLEINLLHAPQNADAIM
GGQKFTHYNRLRIGGLCEKAGLYQRALEHYTDLADIKRVLSHAGHMVNQEFLVSYFGSLN
PEDRMECMRDFLRTNPRQNLQLVVAIAVSYSDQITPEAIIAMFESFRLYEGLYLYLTQVV
VTSTSPEVHFKYIEAAAKINQFKEVERMCRDSNYYDPEKTRDFLKEAKLPDQLPLIIVCD
RYEFISDLTNYLYKNNLSKYIEAYVQKINPVNTPLVVGALLDLDCQEDYLRNLIMSVRNM
CPADSLVEQVEKRNRLKLLLPWLEARVAEGNIEPAIHNALAKIYIDSNKNPEAFLLHNQF
YDSKVVGKYCEKRDPYLSFVAYKRGLCDYELIEVTNKNTLFKNQARYLVERQDPDLWAYV
LSDQNEYKRSLIDQVVQTALPESTNATEVSATVKAFMDANLPNELIELLEKIVLEGKEFK
TAKELQNLLILTAIRADKSRVTDYINRLDNFDGSKLAPIAIESQLYEEAFFMYKKFQFNV
EAIDVLITHIGSIERAHDFAERCNQTEVYSKLGVAQLKAEMVKECIESFIKANDTEHYQE
VVAAAERKDEYEDLVKFLQMCRKKIKEPAIESELIFAYAKVNKLAEMEDFINSPNSAHIQ
VVGDRCFENGLYEAAKVLYTNISNFSRLTSCLVKLGQYQAAVDAARKANSTKTWKEVSAA
CIDAKEFRLAQVCGINIIVHGDELEELIRQYEDRGYFNELISLLESGLASERAHVGMFTE
LAILYSKYKEEKLMEHLKLFYSRLNVPKVIKACQANQQWPQLTYLYIHYDEHDNAIQTMI
NHSIEAWDHVLFKETIPKVAKLDLYYSAISFYLEEQPLLINDLLSVLSPRIDHTRAVTLI
RSLGHLPLVKPYLVSAQDQNVAALNEALNELYVEEEDYESLRSSIDANSNFGTIALAQKL
EKHELLEFRRIAAYLYKKNNRWAQSVELSKKDKLYKDAIQSASDSKNPAIGEELLQYFVD
QQNNSAFAACLYTCYDFLKPDAVIELAWRNNILNYSFPYLIQYVKEYTTKVDQLVDDFKA
RQKKTEEEKEQQNIESSQYQPDLTNLSYGYAATGGMLALPPAVGYQQQQQPQQMYNPNQM
MGGFQQNYNQYGGF
NT seq 5085 nt   +upstreamnt  +downstreamnt
atgaccaatttaccaattagatttcaagaagttctccaacttacaaatttaggtattgga
tccaattcaattggtttttcaaccttaacaatggagagtgaaaaatacatttgtattcgt
gaaactacaccagatgataaaaataatgttgtaattattgatactgacaatccatcacaa
attcttagaaaacaaatgaaaacagatgctgcaattatgaatccaaaagaaccaatttta
gcattaaaaattggacaagttttacaattaatttcaattgaacaaaaaatgcaattaaaa
tcatgtcaaatgcaagaaccattagaattttggaaatggatatcaccaaatacattagca
ttagttacagcaacatctgtatttcattggacaaaagaaggtaattcagatccagttaaa
gtttttgatcgtcatccagatttacaaaatacagagattataaactatcgttcagatagc
acacaaaattggttagttttagtagcaattcatcaaagagatggacgtgtagttggtcgt
attcaattatactctgtagagaaacaaatcagtcaatccattgaaggtcatgcagcatgt
tttgccaactacattgtaccaggtgcaactagaccatcaacattgtttgcaatttcatca
cgtactcaaaatgcatcaaagatattggtattggaggttagtaaaggtgatggaccaaac
ttccaaaaacgtgcctctgacgttttctacccaccagagattggtgcttccgatttccca
gtggcaatgcaagtctctgaaaagtatgaagtcatctatatggtcactaaattgggttac
attcatctctttgatttgggtacagcaaatctcatctacagaaatcgtattagcaatgaa
aatatatttgtaactgctttcgaagagagcaccaacggtatcattgccgtcaatagaaag
ggtcaagtcttatcggtttcaatcgatgacaaaaacatcattccatacatttgcaataca
ctcaacaatttagagttggccatttcaatggcttgtaaaaacaatttaccaggtgctgaa
ggtttactcaccactcaattcgaacgttatttccaacaaggtcaatataaagaggccgcc
aaagttgctgcagattcacctggctctatcttgcgtaaccttcaaaccattcaaaagttc
caatccattccaccaattccagatcaaccatctgctctccttcaatactttggtatgtta
ttagaaaagggtaaactcaataaagttgaatccctcgaattggttcgtccagttttagct
caaggtaaaaaaccaatccttgagaaatggttaactgaagacaaattagaatgttccgaa
caattgggtgatgaagttcgtccacatgatcgtaaattagcactttcaatctattatcgt
gcaaatgcctctgataaagtgatcactttattcgctgaaactggtgaattcgacaaaatc
atcgcctactgtaagaaattcaattataaaccagactttatgttcttacttcaacgtatg
gcaaatgctaatccaatgggtgccgcagatttcgccgttaaattggttaaagaagaaggt
ggtccatacattgatgccaatcaagtcgttgaacttttctctgctcgtaatatgattcaa
gaaactagtaacttcctctttgccattctcgatggtgatcgtccacaagatgcaaacctt
caaaccaaactcttggagatcaatctcttacatgcaccacaaaacgccgatgccattatg
ggtggtcaaaagtttacacattacaatcgtcttagaatcggtggtctttgcgaaaaagct
ggtctctatcaacgtgccctcgaacattacactgatctcgccgatattaaaagagtttta
tctcatgctggtcatatggtgaatcaagagtttttggttagttattttggttccctcaat
ccagaggatcgtatggaatgtatgcgtgatttccttcgtaccaacccacgtcaaaatctt
caattggttgttgcaatcgccgtttcatacagtgaccaaatcactccagaagcaatcatt
gccatgtttgaatctttccgtctctatgagggtctttatctctacttaactcaagtcgtc
gtaaccagtacctcaccagaggttcattttaaatacattgaagccgccgctaaaatcaat
caattcaaagaggtcgaacgtatgtgtcgtgattcaaactactatgatccagaaaagact
cgtgactttttaaaggaagctaaattaccagatcaattaccattgatcattgtttgtgat
cgttacgaattcatctctgatcttaccaactatctctacaaaaacaatctctccaaatat
atcgaagcctacgttcaaaagattaatccagtcaatacaccattggttgtaggtgcactt
ttggatttagattgtcaagaggactatttacgtaatctcattatgagtgttagaaatatg
tgtccagccgattctttagttgaacaagttgaaaagagaaatcgtttgaaacttttactt
ccatggttagaggcaagagttgccgaaggtaacattgaaccagccattcacaacgctttg
gccaagatttacattgattccaataagaatccagaagctttcctcttacacaatcaattc
tatgatagtaaagtcgttggtaaatattgtgaaaaacgtgatccatacctttcattcgtt
gcctacaaacgtggtttatgtgattatgaattgattgaagtcaccaataagaataccctc
ttcaagaatcaagcacgttatcttgttgaacgtcaagatccagatctttgggcttacgtt
ttatccgatcaaaatgaatacaagagatctctcattgatcaagtcgttcaaaccgctctc
ccagaatcaaccaatgccaccgaagtttctgcaactgtcaaggctttcatggatgcaaac
ttaccaaatgaattgattgaattacttgaaaagattgttctcgaaggtaaagaattcaaa
actgccaaagaactccaaaatcttttaattctcactgctattcgtgccgacaagagtcgt
gtcactgattacattaatcgtttagataactttgatggttcaaaattagcaccaatcgcc
attgaatctcaactctacgaagaagccttctttatgtacaagaaattccaattcaatgtt
gaagctatcgatgttttaatcactcatattggttcaattgaaagagctcatgatttcgct
gaacgttgtaatcaaaccgaggtttacagtaaattgggtgttgctcaattgaaagcagaa
atggtcaaagaatgtattgaatcattcattaaagccaatgatactgaacattatcaagag
gttgtcgctgccgctgaaagaaaagatgaatatgaagatttggttaaattccttcaaatg
tgtcgtaagaagattaaagaaccagccattgaaagtgaattgatctttgcttatgctaaa
gttaacaaattggccgaaatggaagatttcatcaactcaccaaactctgctcacattcaa
gtcgttggtgatcgttgtttcgaaaatggtctctatgaagctgccaaagtactctatacc
aatatttccaacttttcacgtcttaccagttgtctcgtcaaattaggtcaatatcaagct
gccgtcgatgctgcacgtaaagccaactccaccaaaacttggaaagaagttagtgctgct
tgcatcgatgccaaggaattccgtttggcacaagtttgtggtatcaatatcattgtacat
ggtgatgaacttgaagaattaattcgtcaatatgaagatcgtggttatttcaatgaatta
atttccctcttagagagtggtcttgcctctgaacgtgctcatgttggtatgttcaccgaa
ttggctattctctactctaaatacaaagaggagaaattaatggaacacttaaaacttttc
tacagtcgtctcaatgttccaaaggttatcaaagcttgtcaagccaatcaacaatggcca
caactcacctacttatacattcattacgatgaacatgataatgccattcaaaccatgatc
aatcattccattgaagcttgggatcatgttctctttaaagaaaccattccaaaggttgcc
aaattggatctctactatagcgccatctcattctatttagaggaacaaccattactcatc
aatgatctcttatcggttttatcaccacgtatcgatcatactcgtgccgtcactttaatt
cgttcattaggtcatctcccattggttaagccatacttggtatctgctcaagatcaaaat
gtagccgctctcaatgaagctctcaatgaattatacgtcgaagaagaggattatgaatcc
ttgagatcctcaatcgatgccaactccaactttggcaccattgctctcgctcaaaaactt
gaaaaacatgaactcctcgaattccgtagaatcgccgcctatttgtacaaaaagaataat
cgttgggctcaatcagttgaactctctaaaaaagataaactctacaaagatgccattcaa
tctgcctcagactcaaagaatccagccattggcgaagaacttttacaatactttgttgat
caacaaaataatagtgcctttgctgcttgtctttacacttgttacgactttttgaaacca
gatgctgtcatcgaattggcttggagaaataatatcctcaattactcattcccatatctc
attcaatacgttaaagaatatacaaccaaagttgatcaattggtcgatgatttcaaagct
cgtcaaaagaaaactgaagaagaaaaagaacaacaaaatattgaatcctctcaatatcaa
ccagatcttactaacctctcatatggttacgcagccactggtggtatgttagctcttcca
ccagctgtaggatatcaacaacaacaacaaccacaacaaatgtataatccaaatcaaatg
atgggtggtttccaacaaaattataatcaatatggtggtttttaa

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