Dictyostelium discoideum (cellular slime mold): DDB_G0286335
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Entry
DDB_G0286335 CDS
T00245
Symbol
bkdA
Name
(RefSeq) 3-methyl-2-oxobutanoate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ddi
Dictyostelium discoideum (cellular slime mold)
Pathway
ddi00280
Valine, leucine and isoleucine degradation
ddi00640
Propanoate metabolism
ddi00785
Lipoic acid metabolism
ddi01100
Metabolic pathways
ddi01110
Biosynthesis of secondary metabolites
ddi01210
2-Oxocarboxylic acid metabolism
Module
ddi_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ddi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DDB_G0286335 (bkdA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DDB_G0286335 (bkdA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DDB_G0286335 (bkdA)
Enzymes [BR:
ddi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DDB_G0286335 (bkdA)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
8625523
NCBI-ProteinID:
XP_637809
dictyBase:
DDB_G0286335
UniProt:
Q54M22
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Position
4:4250107..4251736
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AA seq
441 aa
AA seq
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MISQSYRILSRISRNNELKKTFLTNLNCKSSSPSIIRSFCKKQNLDENFEYTNKLEVQEL
KHYIPCYTIMDQEGVVSKPDQDPNFSKEEVIKMYTTMLTLNVMDSILYDVQRQGRISFYM
TSFGEEAIHIGSAAALEMSDTIFAQYRETGVFMWRGFTINDIINQCCTNEHDLGKGRQMP
MHFGSRKINLQTISSPLTTQLPQAVGSSYAQKLAGEKNCTIVYFGEGAASEGDFHAAMNF
AAALSTPTIFFCRNNKWAISTPSKEQYKGDGIAGRGPNGYGMKTIRVDGNDIWAVYNVTK
LARKIAVEEQVPVLIEAMTYRVGHHSTSDDSSRYRTVEEINAWKEGKNPISRLRNYMNHK
GWWSDAQEKETIANARTTVRESLVNAEKQYKPSINEIFTDVYDKPTPNLIEQQKELIEHL
KLYPDEYPLNQFADSKLILKD
NT seq
1326 nt
NT seq
+upstream
nt +downstream
nt
atgataagccaatcttacagaattttatcaagaatcagtagaaataatgaattaaaaaaa
acctttttaaccaatttaaactgtaaatcatcatcaccatcaattatcagaagtttctgt
aaaaaacaaaatttagatgaaaattttgaatatacaaacaaattagaagttcaagaactt
aaacactatataccatgttatactattatggatcaagaaggtgtcgtttcaaaacctgac
caagacccaaattttagtaaagaagaagttattaaaatgtatacaacaatgttaacatta
aatgttatggattcaattctttatgatgtacaaagacaaggtagaatttcattttatatg
acatcatttggtgaagaagcaattcatattggatcagcagcagcattagagatgagtgat
acaatttttgcacaatatagagagactggtgtattcatgtggagaggattcacaatcaat
gatattatcaatcaatgttgtaccaatgaacatgatttaggtaaaggtagacaaatgcca
atgcatttcggttcaagaaagattaatcttcaaactatttcatcaccattaacaactcaa
ttaccacaagcagtgggtagctcatacgctcaaaaattagcaggtgaaaagaattgtacc
atcgtttactttggtgagggtgctgcaagtgagggtgatttccatgctgctatgaatttc
gccgcagcattgtcaacaccaactatctttttctgtcgtaacaataaatgggcaatctct
acaccctcaaaagagcaatacaaaggtgatggtattgctggtcgtggtccaaatggctac
ggtatgaaaactatcagagtcgatggtaacgatatttgggccgtatacaatgtgactaaa
ttagcacgtaaaatcgccgtcgaagaacaagttccagttctcatcgaagctatgacctat
cgtgttggtcatcattctacctctgatgactcttctcgttatcgtactgttgaagagatc
aacgcttggaaagaaggtaaaaatccaattagtcgtttaagaaactacatgaatcacaaa
ggttggtggagtgatgctcaagagaaggaaactatcgcaaacgctcgtactaccgttcgt
gaatccttagtcaacgctgaaaaacaatataaaccatcaatcaatgaaatctttaccgat
gtttatgataaaccaactccaaatctcatcgaacaacaaaaagaattaattgaacatttg
aaattatatccagatgaatatccattaaatcaatttgctgattcaaaattaattttaaaa
gattaa
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