Delphinus delphis (saddleback dolphin): 132420292
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Entry
132420292 CDS
T11117
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
ddp Delphinus delphis (saddleback dolphin)
Pathway
ddp01521
EGFR tyrosine kinase inhibitor resistance
ddp01522
Endocrine resistance
ddp04010
MAPK signaling pathway
ddp04012
ErbB signaling pathway
ddp04014
Ras signaling pathway
ddp04062
Chemokine signaling pathway
ddp04068
FoxO signaling pathway
ddp04072
Phospholipase D signaling pathway
ddp04150
mTOR signaling pathway
ddp04151
PI3K-Akt signaling pathway
ddp04510
Focal adhesion
ddp04540
Gap junction
ddp04630
JAK-STAT signaling pathway
ddp04650
Natural killer cell mediated cytotoxicity
ddp04660
T cell receptor signaling pathway
ddp04662
B cell receptor signaling pathway
ddp04664
Fc epsilon RI signaling pathway
ddp04714
Thermogenesis
ddp04722
Neurotrophin signaling pathway
ddp04810
Regulation of actin cytoskeleton
ddp04910
Insulin signaling pathway
ddp04912
GnRH signaling pathway
ddp04915
Estrogen signaling pathway
ddp04917
Prolactin signaling pathway
ddp04926
Relaxin signaling pathway
ddp04935
Growth hormone synthesis, secretion and action
ddp05034
Alcoholism
ddp05160
Hepatitis C
ddp05161
Hepatitis B
ddp05163
Human cytomegalovirus infection
ddp05165
Human papillomavirus infection
ddp05200
Pathways in cancer
ddp05205
Proteoglycans in cancer
ddp05206
MicroRNAs in cancer
ddp05207
Chemical carcinogenesis - receptor activation
ddp05208
Chemical carcinogenesis - reactive oxygen species
ddp05210
Colorectal cancer
ddp05211
Renal cell carcinoma
ddp05213
Endometrial cancer
ddp05214
Glioma
ddp05215
Prostate cancer
ddp05220
Chronic myeloid leukemia
ddp05221
Acute myeloid leukemia
ddp05223
Non-small cell lung cancer
ddp05224
Breast cancer
ddp05225
Hepatocellular carcinoma
ddp05226
Gastric cancer
ddp05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ddp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132420292 (SOS2)
04012 ErbB signaling pathway
132420292 (SOS2)
04014 Ras signaling pathway
132420292 (SOS2)
04630 JAK-STAT signaling pathway
132420292 (SOS2)
04068 FoxO signaling pathway
132420292 (SOS2)
04072 Phospholipase D signaling pathway
132420292 (SOS2)
04151 PI3K-Akt signaling pathway
132420292 (SOS2)
04150 mTOR signaling pathway
132420292 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
132420292 (SOS2)
04540 Gap junction
132420292 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132420292 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
132420292 (SOS2)
04660 T cell receptor signaling pathway
132420292 (SOS2)
04662 B cell receptor signaling pathway
132420292 (SOS2)
04664 Fc epsilon RI signaling pathway
132420292 (SOS2)
04062 Chemokine signaling pathway
132420292 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
132420292 (SOS2)
04912 GnRH signaling pathway
132420292 (SOS2)
04915 Estrogen signaling pathway
132420292 (SOS2)
04917 Prolactin signaling pathway
132420292 (SOS2)
04926 Relaxin signaling pathway
132420292 (SOS2)
04935 Growth hormone synthesis, secretion and action
132420292 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
132420292 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
132420292 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132420292 (SOS2)
05206 MicroRNAs in cancer
132420292 (SOS2)
05205 Proteoglycans in cancer
132420292 (SOS2)
05207 Chemical carcinogenesis - receptor activation
132420292 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
132420292 (SOS2)
05231 Choline metabolism in cancer
132420292 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
132420292 (SOS2)
05225 Hepatocellular carcinoma
132420292 (SOS2)
05226 Gastric cancer
132420292 (SOS2)
05214 Glioma
132420292 (SOS2)
05221 Acute myeloid leukemia
132420292 (SOS2)
05220 Chronic myeloid leukemia
132420292 (SOS2)
05211 Renal cell carcinoma
132420292 (SOS2)
05215 Prostate cancer
132420292 (SOS2)
05213 Endometrial cancer
132420292 (SOS2)
05224 Breast cancer
132420292 (SOS2)
05223 Non-small cell lung cancer
132420292 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
132420292 (SOS2)
05160 Hepatitis C
132420292 (SOS2)
05163 Human cytomegalovirus infection
132420292 (SOS2)
05165 Human papillomavirus infection
132420292 (SOS2)
09165 Substance dependence
05034 Alcoholism
132420292 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132420292 (SOS2)
01522 Endocrine resistance
132420292 (SOS2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
IQ_SEC7_PH
PH_10
Motif
Other DBs
NCBI-GeneID:
132420292
NCBI-ProteinID:
XP_059860579
LinkDB
All DBs
Position
2
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRDLFKPSDI
EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEHEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAVELSQDHFKKYLLKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGNASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPSGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPN
TPPSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatcccaacag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggcttggtttctctttgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcttttctttctgacagagacctgtttaaaccttctgatatt
gaaaaaattttcagtaacattttagatatacatgaattgaccgtgaaacttttaggttta
attgaagacacagttgaaatgacagatgaaagcagccctcatcccttagctggaagctgt
tttgaagatttggcagaggaacaagcatttgatccttatgaaacattatcacaggatatt
ctttcaccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctcttatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaatttattatggaaggcccattgacaagaattggtgctaaacacgaacggcacattttt
ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcacgccttccagga
tacagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt
gataaagaagatacttgtgagtgcaaacatgcttttgaattagtatccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtattactgaaggaagaa
aatgaacaaccacttagattaccgagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaaggttaacatatcacatgtatgcagatcccaat
tttgttcgcacttttcttactacgtatcgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gtagagaaaggcgagcagccaatcagtgcagaccttaaaaggtttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagacttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcaaccttct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccacaccacaaatctcactctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcagtactaagtagaataatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattagagatcgtcagtgcagtaaattcagtatca
gtctatagactagatcatacctttgaggcattgcaggaaagaaaaaggaaaattttggat
gaagctgtggaattaagtcaagatcattttaaaaaatatctattgaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcaatatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggaggttctttgaaaaccttaaccccatgggaaatgcttctgaa
aaagagtttacagattatctgttcaacaagtcactagaaattgaaccccggaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggtactttacgaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaacagagcttgaatcaacagtg
tcagcaccaacctctccaaatacaccatctactccaccagtgtctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca
gtcctcttgcctcattcaaagtctttctttagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctcctcgaaaaaaatttgatcatgatgcttca
aattccaagggaactatgaaatctgatgatgacccccctgctattccgccaagacagcct
cctcctccaaaggtaaaacccagagttcctgctccttctggtgcatttgacgggcctctg
catagtccaccaccgccgccgccgagagatcctcttcccgatacccctccaccagttccc
cttcggcctccagaacactttataaactgtccgtttactcttcagccacctccactggga
catcttcacagagatccagactggttcagagacgttagtacgtgtccaaattctccaaac
actcctcctagcacaccctctccaagggtaccacgtcgatgctacgtgctcagttctagt
cagaataatcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgggagctttcgcaccccccattgtat
agactgcctttgctagaaaatgcagaaactcctcaatga
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