Delphinus delphis (saddleback dolphin): 132422755
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Entry
132422755 CDS
T11117
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ddp Delphinus delphis (saddleback dolphin)
Pathway
ddp04217
Necroptosis
ddp04380
Osteoclast differentiation
ddp04620
Toll-like receptor signaling pathway
ddp04621
NOD-like receptor signaling pathway
ddp04630
JAK-STAT signaling pathway
ddp04658
Th1 and Th2 cell differentiation
ddp04659
Th17 cell differentiation
ddp05145
Toxoplasmosis
ddp05160
Hepatitis C
ddp05161
Hepatitis B
ddp05162
Measles
ddp05164
Influenza A
ddp05165
Human papillomavirus infection
ddp05167
Kaposi sarcoma-associated herpesvirus infection
ddp05168
Herpes simplex virus 1 infection
ddp05169
Epstein-Barr virus infection
ddp05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ddp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
132422755 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
132422755 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
132422755 (TYK2)
04621 NOD-like receptor signaling pathway
132422755 (TYK2)
04658 Th1 and Th2 cell differentiation
132422755 (TYK2)
04659 Th17 cell differentiation
132422755 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
132422755 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
132422755 (TYK2)
05160 Hepatitis C
132422755 (TYK2)
05171 Coronavirus disease - COVID-19
132422755 (TYK2)
05164 Influenza A
132422755 (TYK2)
05162 Measles
132422755 (TYK2)
05168 Herpes simplex virus 1 infection
132422755 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
132422755 (TYK2)
05169 Epstein-Barr virus infection
132422755 (TYK2)
05165 Human papillomavirus infection
132422755 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
132422755 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ddp01001
]
132422755 (TYK2)
Enzymes [BR:
ddp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
132422755 (TYK2)
Protein kinases [BR:
ddp01001
]
Non-receptor tyrosine kinases
JAK family [OT]
132422755 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
FERM_C_FAK1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
132422755
NCBI-ProteinID:
XP_059863694
LinkDB
All DBs
Position
3:complement(8606530..8628618)
Genome browser
AA seq
1185 aa
AA seq
DB search
MPLCQWGATTRGRKPDGDGAQPMATRGGLKVLLHWAGPGGGEPWVTFSEATLTAEEVCLH
IAHKVGITPPCFNLFALFDVQAQVWLPPNHVLDMSRDSSLMLYFRMRFYFRNWHGMHPQE
PAVYRCGPPGSEPSSEQTEQGVQLLDPASFEYLFEQGKHEFINDVASLWELSSEEEIHHF
QNESLGMAFLHLCHLALCHGVPLEKVAKKISFKDCIPRSFRRQIRQHNALTRLRLRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEGEPCYIRDGGQA
PPDPGPESAAGPPTHEVLVSGTDGIQWRLVQAETASDGGGGGGRRMPHAGPSGKKAKAQE
VGNQPVYRPQEAPWAYFCDFQDITHVVLKERRVSIHCQDNKCLELTLPSRAAALSLVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLARLQPEDGLYLIHWSTSHL
HRLILTVAQRDQAPGVKGLHLRKFPIELQAGTVTLEGWDRSFPSVRELRVALQGCSLRAG
DDCFSLRHCCLPRPGEISNLIVTRGPRASSRPLNLSHLSFHQIRQEDITQLSHLGQGTRT
NVYEGLLRVGGGGPEEDKVDGGDPPMPGAGCEQELRVVLKVLDPSHHDVALAFYETASLM
SQVSHVHLVFVHGIYVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLTVAQQLASAL
SYLEDKSLVHSNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSVLSREERVERIPWTAPE
YLSGGANSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQQKLPEPSCPELA
ILTSQCLTYEPAQRPSFRTILRDLTQLQPQNLVDVLSVNPDSPASDPTVFHKRYLKKIRD
LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRTGWRREIEILRTLYHQHIVKY
KGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFSQQICEGMAYLHAQHYVHR
DLAARNVLLDNNRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYYAS
DVWSFGVTMYELLTYCDSTQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPEKCPC
EIYCLMKNCWKAEASFRPTFQNLIPILKTVHEKYQGQAASVFSVC
NT seq
3558 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaatggggggccaccaccaggggcagaaagcccgatggggatggagct
cagcccatggccaccagaggaggcctgaaggtgcttctgcactgggccggccccggtggc
ggggagccctgggtcaccttcagcgaggccacactgactgccgaggaggtctgcctccac
attgcacacaaagtcggcatcactccaccctgcttcaatctttttgccctcttcgatgtc
caggcccaggtctggctgcctccaaaccacgtcctggatatgtccagagactcgagcctg
atgctgtacttccgcatgaggttttatttccggaactggcatggcatgcatccccaggag
ccggctgtgtaccgctgtggtcccccagggtccgagccttcctcagaacagaccgagcag
ggggtgcaactcctggaccccgcctcctttgagtacctctttgagcagggcaagcatgag
ttcataaatgacgtggcatcgctctgggagctgtcaagcgaggaggagatccaccacttt
cagaacgagagcctgggcatggcctttttgcacctctgccacctcgctctctgccatggt
gtcccccttgagaaggtggccaagaagatcagcttcaaggactgcatcccacgctccttc
cggcggcagatccggcagcacaatgctctgacgcggctgcgcctgcggagcatcttccgc
aagttcctgcgggccttccagccgggctgcctctcccagcaggttgtcatggtgaagtac
ctggccacactcgagcggctggcgccgcgcttcggcacagagcgcgtgcccgtgtgccac
ctggagctactggcccaggccgagggggagccctgctacatccgggatggcggacaggcc
cctcccgaccccgggcccgagtctgctgcaggaccccccacccacgaggtgctggtgtcg
ggcaccgacggcatccagtggcggctggtacaggcagagactgccagtgatggtggtggt
ggtggcggcagaaggatgccccatgctggcccatctgggaagaaagccaaggcccaggag
gtgggcaatcagccagtgtacagacctcaggaggccccatgggcctacttctgcgacttc
caggacatcacccacgtggtgctgaaagaacgccgcgtcagcattcactgtcaggacaac
aagtgcctggagttgaccctgccttcccgggctgcggccctgtccttggtgtcactggtg
gatggctacttccgcctgacggccgactcgagccactacctatgccatgaggtggcgcct
ccgcgtctggtgatgagtatccaggacggtatccacggacccctgctggagccatttgtg
ctggccaggctgcagcccgaggacggcctttacctcatccactggagcaccagccacctc
caccgccttatcctcacggtggcccagcgtgaccaggcacccggcgtgaagggcttgcac
ctacggaagttccccatcgagttgcaggctgggactgtcacgctggagggctgggaccgg
tccttccccagcgtgcgcgagctgcgggttgccctgcagggctgctccctgcgggccggc
gacgactgcttttccctgcgccactgctgcctgccacggccaggagagatctccaacctc
atcgtcacacggggacctcgggccagcagcaggccactcaacctcagccatctcagcttc
caccagatccgccaggaagacatcacccagctgtcccacttgggccagggcacaaggacc
aatgtgtatgagggcctcttgcgagtggggggcggaggccctgaagaggacaaggtggat
ggcggggacccccccatgcccggggcgggctgtgaacaggagctgcgagtggtactcaag
gtgctggatcccagtcaccatgacgtcgccctggccttctacgagacagccagcctcatg
agccaggtctcccacgtgcacctggtcttcgtgcacggcatctacgtgcacggctccgag
aatatcatggtgacggagtacgtggagcacgggcccctggacgtgtggctgcggcgggag
aggggccgcgtgcccctggcctggaagctcacagtggcccagcagctggccagcgccctc
agctacctggaagacaagagcctggttcacagcaacgtgtgtggccggaacatcctcctg
gcacggctggggctggcggagggcaccagccccttcatcaagctgagtgaccccggtgtg
ggcctcagcgtcctctccagggaggaacgggtggagcggatcccctggacagcccctgag
tacctgtccggtggagccaacagcctaagcactgcagctgacaagtggggctttggtgcc
accctcctggagatctgcttcgatggggaggcccccctgcagggccgcagcccctccgag
aaagagcgcttctaccagaagcagcagaagctgcctgagccctcgtgcccagagctggcc
atactcaccagccagtgcctgacctatgagccagcccagcggccatccttccgcaccatc
ctgcgtgacctcactcagctgcagccccaaaatctcgttgatgtcttgtctgtgaacccg
gactcaccggcgtcagatcctacggttttccacaagcgctatttgaaaaagatcagggat
ctgggtgagggtcacttcggaaaggtcagcctgtactgctacgatccaaccaatgacggc
actggtgagatggtggccgtgaaggccctcaaggcaggctgcggtccccagctccgtaca
ggctggaggcgagagatcgaaatcttgcgcacactctaccaccagcacattgtcaagtac
aagggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggagtacgtgccc
ctgggcagcctccgagactacttgcctcggcacaatgtcgggctggcccagctgctgctc
ttctcccagcagatctgcgagggtatggcctacctgcacgcgcagcactacgtgcaccga
gacctggccgcacgcaacgtgctgctggacaacaacaggctggtcaagattggggacttc
ggtctcgccaaggccgtgcccgaaggccatgagtactactgtgtgcgcgaggatggggac
agtcccgtgttctggtatgccccggagtgcctgaaggagtgtaagttctactatgcgtct
gacgtctggtcctttggggtcaccatgtatgagctgctgacctactgtgactccacccag
agccccccctcgaaattcatcgagctcataggcctcacccaggggcagatgacagtgctg
aggctcactgagctactggaacgaggggagaggctgccacagccagagaaatgtccctgt
gagatctactgcctcatgaagaactgctggaaagcagaggcctcattccgcccgaccttc
cagaacctcatacccatcctcaaaacggtccacgagaaataccaaggccaggcagcctca
gtgttcagtgtctgctga
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integrated database retrieval system
