Delphinus delphis (saddleback dolphin): 132426977
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Entry
132426977 CDS
T11117
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
ddp Delphinus delphis (saddleback dolphin)
Pathway
ddp05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
ddp00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
132426977 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
ddp03021
]
132426977 (SETX)
Enzymes [BR:
ddp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
132426977 (SETX)
5.6.2.5 RNA 5'-3' helicase
132426977 (SETX)
Transcription machinery [BR:
ddp03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
132426977 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
SLFN-g3_helicase
nSTAND3
AAA_16
ResIII
NAT10_TcmA_helicase
UvrD_C_2
Tubulin
Motif
Other DBs
NCBI-GeneID:
132426977
NCBI-ProteinID:
XP_059869885
LinkDB
All DBs
Position
6:4284636..4364914
Genome browser
AA seq
2684 aa
AA seq
DB search
MSTCCWCTPGGISTIDFLQHYASETHSSEFQKADEDLCYCLECVAEYHKARDELPSLHKV
LWELETSRLINHFEKAMKAEIGDDDELYIVDDNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLETGKLILLPSHMYDAANYKNYWLG
ICMLLTILEEQAMDSLLLGSNKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNKEIQNIRNSSMRSKFKPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDTVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTMISSLSLHSMPSNSVQLACVQLIRS
LLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKVPQ
CSTSVDLTSPCKTPPASYNKEESEQTGKKSKKDRHCLENSSPTFSKEPMKADACQVQESI
FSKADNAIEEDNERTYIKDLKLKDHLSAELCLKPSSKRLVNERARGQVKISTGKHKSVKE
NSSYTPQNCTSRNGPEKVFDRGIITSTRLLTDSSNDSLEKVSTSNEDFSLKGDALGKTSK
AKTKAHKDEICAKLSHVVKKQHRKSITLEENLTVSSIESFYSKKDTGGQKGDGFIYNLSL
GPNGILDDKNGEQKSENSLLLKKKQVKEEELGILSTRELSCQILECHVGNKDLVSFTEMT
NIFVEKTPPFKDPVTGLESRDMEIIKSTAQFSSDLREQVLSSPKSDTLTDSQVDRDLHKL
SLVAQASVIKFPSDSTQKSLSQLQRKVKDDRRCFTANQNSVRETCCEQVIIISDSDEDDD
DDERIVGFKKHIKQDKTCIEKECPEQHASIANTNVEQKVIREENTGSLLQFEESESQFFE
FESPCEVFSVWQDQKPDNKNSVQENEENSCLTHVGDTTNDWGYGTDYVPEEVIKKAAEDI
EEHAEPHSSSISVEEFCEIEVKKPKRKRYQKAAMAEAPLRPSSPVKSEDQSDILNERDVT
ENDFKSIDVRSTTPSSSVQRTTTVSLKKSPPKLRNCSKRVSRVSLSKTPKKTRSDTKTGQ
SKSSNILSCRTSPAIVLPKKFRQRPEPTSTVEKLGLKKVARRAFDLSQPSLERLADLRHH
GRTVGAIDTRKKTKLISPQTLSVRNNEKLLTSQDRQLRRQMRPKSQRNRKRCFDYQSTDT
TRAGPQGAQNSDKFVPESDTSDYSYKGGVEVTAKSKETELIKCVSSETEPVKTEYVSQVA
DDPCLLNQGTSVVLHGEIPTNEVVVSISGDPLGGGDLTVHHLAVAALREGDPESSNDIEE
DNIFLTQCDPEDMDLCSQMEKENDKLVEVVHGKDTVQVEECYVSRPQLESSSSTKCKYKD
CVETLKNQGEYCSKHSEAKAADEAVFRKPGLPLSASKPSRPPTAKIFSSSSTSRIAGLSK
SLENTAALLPTLKNKSSGVQSVLKVPPVSLVSKKPVAEVKGLCNVLHSHAPNNSNRQGYK
VPYCENRSFSASPPVNVLLSAQSISDTFVKEVLKWKYEMFVNFDQCGPPSTLCQSISRPV
PVRFQDGGDYFNVFFPLMMLNTFETVAQEWISSPNKEKFHRLHLRKFPSEYKKYWEFVVY
LEECELAKQLHPKENDLVFLVPERLNGEEEDIERNRMQDPYEYYCGYVHKFRRTSVMHNG
KSECSVSIQTQHNLPVNLNEFVKCLVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMD
FCTKDLLTAASEKIIAHLKDFNEDQKKAIETAYAMVRHSPAVAKICLIHGPPGTGKSKTI
VGLLYRLLTERRGLSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILQFKGKCKDKKNPL
GNCGDINLLRLGPEKSINAEVLKFSLDSQVNHRMKKELPSHIQEMHRRKEFLDHQLDELS
RQRALCRGGRELQRQELDEKIARVSKERQELASKVKEVQGRPQKTQNTIILESHIICCTL
STSGGLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTV
ISVKAQEYGYDQSMMARFYKLLEENVKHNVIGRLPVLQLTVQYRMHPDICLFPSNYVYNR
NLKTNRITEAIRCSSDWPFQPYLVFDVGDGSEKRDNDSYVNVQEIKLVMELVKLMKDKKR
DFTYRNVGIITHYKAQKMMIQKDLDKEFDRKGPAEVDTVDGFQGRQKDCVIVTCVRANAM
QGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENCHWNQLIQDAQKRGAIVKTWDKNY
RQDAVKILKLKPVLQRSLTHPPAIAPEVSRPQGGVPSNKLDSEFAKMSIASSLYPSPSDS
KEATVTVTANDPERPPIQDWLRDPRLLRRMGLGCEAKGKCLSELQPSSPQYPGAAPLSGE
PGSPGRHQDPTSIGQQPPAKGAAVNNHRPHAQCDPPAASTDASTSKRKCAQEGEAVSHRR
ETRAFPEGDQETCGSLSHHTKRNSGWDERGLEEEDSSLKKRKLS
NT seq
8055 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacaccaggtggtatttccaccattgacttcctgcaacac
tatgcatctgagacccactccagtgaatttcaaaaagctgatgaagacctctgctactgc
ttagagtgtgtggctgagtaccacaaagcaagggatgaattgccatccttacataaggtt
ttatgggaattagaaacctcacgtctcataaatcactttgaaaaggccatgaaggcagaa
attggagacgatgacgagttatatatagtagacgacaatggagaggcacagctgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatttgcttttacatgagcgtgttaatgaactatgcgttgaagcactttgccggatg
gaacaagctaactgctcctttcaggtttttgacaaacatccagggatctatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgactgcaagaaacttgggaaaa
gtggacagagatgattattatgacttacaggaggttttgacttgcctttttaaagtcatt
gagttggggcttttagaaagtccagacatttatacttcttctgtccttgagacgggtaaa
ctgattcttctgccttcacacatgtatgatgctgccaactacaaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca
aacaaacagaatgattttatgcaatcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt
ggatccaaggtctggggtcaacttattgatcctattgaggcatttcaaaccattatcaac
aacgtgagctacaataaggagattcagaatatacggaacagctctatgaggtccaagttc
aaaccagagtcatatttggatgatatggtgacttgcagccagattgtatacaattataac
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagctaatgtgcttcagtcagatatcggtcaagac
atgcgtgttcataacagcacgtttctgtggttcatcccttttgtgcagtccctcatggat
cttaaggatctgggtgtggcttatatagtggaggttattcatcatctgcattctgaagtc
aaagacgtcctcaaccagacagacgccgtgtgtgacacagtcactgagtttttccttctg
attttggtgtcagtgattgaactgcatagaaataaaaagtgtttgcatttgctgtgggtt
agttcccagcagtgggtggaagccgtcgtaaaatgtgccaagcttcccaccaccgcattt
gcacggagttctgagaagtcatctggaaactgctccaaaggcacaatgatatcatctctg
tcattgcattcaatgccatctaactctgtacaacttgcttgtgtgcagctgatcagaagt
ctccttaaagaaggctatcagcttgggcagcagactctttgtaagcgattctgggataag
ctcaacttattcctgcgaggaaatttatctttaggttggcagttgactagtcaggaaacc
catgagttacaaacttgtttaaagcaaattattagaaacataaaattcaaagtacctcaa
tgtagcacttctgtggatctgacttctccatgtaaaacgcctcctgcatcatataataaa
gaagaaagtgaacaaacagggaagaagtctaaaaaagacaggcactgtctggaaaactcc
agcccaacattctctaaagaaccgatgaaagctgatgcatgtcaagtgcaagagagtatt
ttcagcaaagcagataatgccatagaagaggataatgagcgaacttacataaaagatttg
aaactcaaagaccatctctccgctgagttgtgcttgaagccgagtagtaaaaggcttgtt
aatgaaagagctcgaggccaagttaaaataagtacagggaagcataaatctgtaaaagag
aattcctcatataccccacagaattgtacttcaagaaatggtccagaaaaggtatttgac
agaggaataataacatcaacacgtttgttgactgattctagcaatgactctctggaaaag
gtgtccacatcaaatgaggatttctctttaaagggtgatgctcttggcaaaacctcaaaa
gcaaaaactaaggcacataaagatgaaatctgtgctaagttatcacatgtagtaaaaaag
caacacaggaaaagtatcactttagaggaaaacctgactgtatctagcattgaaagtttc
tattcaaagaaggatacaggaggtcagaaaggagatggcttcatatacaatctctcttta
ggccctaatggtattctggatgacaaaaatggagaacaaaaatctgaaaacagtttattg
ctgaaaaagaaacaagtaaaggaagaagagttaggcattctctctacccgtgaactcagt
tgtcaaatactagaatgtcatgttggtaataaagatttggtctcatttacagaaatgacc
aacatttttgtggagaaaacacctccctttaaagatcctgtgactggacttgaatcaaga
gatatggaaattatcaagagtactgctcagttttcttctgatttaagagaacaagtcctt
agcagtcctaagtctgacaccttaacagattctcaggtagacagagacctccacaaatta
tctttagtagctcaagccagtgttattaagttcccatcagattcaactcaaaaaagttta
tcccagctacaaagaaaagttaaagatgatagaagatgtttcacagccaaccaaaatagt
gttagggaaacctgctgtgaacaggtcattattatttcagattctgatgaagatgatgat
gatgatgaaagaattgtgggttttaagaaacacattaaacaggataaaacatgcattgag
aaagaatgtccagagcagcatgcttcaatagctaacacaaacgtggaacagaaggtaata
agggaagaaaatacagggtcccttttgcagtttgaggaatctgagtctcagttttttgag
tttgaaagtccatgtgaagtgttttcagtttggcaagatcagaaaccagacaacaagaat
tcagttcaagagaatgaagaaaattcgtgcttgactcatgtaggtgataccacaaatgat
tggggttatggtacagattatgtacctgaagaggtcattaaaaaagcagcagaggacatt
gaggaacacgcagaaccacacagtagtagtatttctgttgaggaattttgtgagattgaa
gtaaaaaaacccaagagaaagcgatatcagaaagctgctatggcagaagctcctctaagg
ccttcatctcctgtcaaaagtgaggaccagtctgatattcttaatgagagagatgtgact
gaaaatgattttaaaagtatagacgtaaggagtacaactcccagttcaagcgttcagaga
accactacggtttccctgaagaagtctccaccaaagcttcgcaattgttccaaacgtgtt
agcagagtctcactttctaaaactcctaaaaaaacacgttcggataccaaaacagggcag
agtaaaagttcaaatatcctaagttgtagaacaagtcctgctatagtgctaccaaagaaa
tttcgccagcgtcctgaaccaacttcaacggttgagaaacttggtctgaaaaaggttgct
cgtagggcatttgacttgtcccagccgtctttggagcgtttagctgacttacgtcaccat
ggcagaactgttggagcaattgatacccggaaaaagactaaattaatttctcctcagact
ctctctgtcagaaataatgagaaactgctgacgagtcaagaccgtcagctgcgaaggcag
atgagacccaaatcacagcgtaacagaaaaagatgttttgattatcagagtacagataca
acacgagcaggcccacagggagcacaaaattctgacaaatttgtgccagaatcagataca
tcagattatagttataaaggaggagttgaggtaactgcgaaaagtaaggaaacagagtta
ataaaatgtgtgtcttctgaaacagaacccgtgaaaacagaatacgtttctcaggtagct
gatgacccttgtcttttgaaccagggtacttctgtagtattacatggagaaataccaaca
aatgaagtagttgtttctatctcaggggaccctttaggtggaggtgacctaacggtacat
catttagctgtggcagccttgagagagggagatcctgaatccagcaatgacatagaggaa
gataatatatttttaacacaatgtgatcctgaagatatggatttatgttcacaaatggag
aaagagaatgataaactcgttgaagtagttcatggaaaagatacagtccaggtagaagaa
tgttatgtgagtcggcctcagttggaatcttcgagtagcacaaaatgtaaatacaaagat
tgtgttgaaacactgaaaaaccagggtgaatactgttcaaaacactctgaagctaaagca
gcggatgaagctgtatttcgtaaacctggcttgcctctctctgcatctaaaccttcgaga
cctcccactgctaagatttttagctccagtagtacttcacgaattgctggtctctccaag
tctttggaaaatacggcagcgctcttaccaactctgaaaaataagtcaagtggggtacag
tctgttttgaaagtaccaccagtctctctggtgtccaagaagccagtggctgaagtgaag
ggtttgtgcaacgttctccattctcatgctccaaataattccaacaggcaaggctacaaa
gttccatattgtgaaaacagatctttttcggcttcccctccagtaaacgttctcttgtca
gcacagtccatctctgacacctttgttaaagaggtcttaaaatggaaatacgaaatgttt
gtgaactttgatcagtgcggacccccgtcaactctttgtcagtccatctcaagacctgtg
cctgtgagatttcaagatggtggagattattttaatgtgtttttccctttgatgatgctg
aatacttttgaaacagtggcacaggaatggatcagctctccaaacaaagagaaattccat
cggttgcatttacgaaaatttccttctgagtataaaaaatactgggagtttgtggtttat
cttgaggaatgtgaactagctaaacagcttcatccaaaggaaaatgatttggtgtttttg
gttcctgaaagactaaatggagaggaggaggacatagagagaaatcgcatgcaagatccc
tatgaatattattgtggttatgttcataaattccgccgcacttcagtcatgcataatggg
aaatctgagtgctccgtttccatccagactcaacataatttaccagtcaatttaaatgaa
ttcgtgaaatgtcttgtaatcagctctctggtgactacacaaaggaagttgaaagccatg
tctttgctgagtggtcggaaccaactggccagagccgttctgaatccaaaccccatggac
ttctgtacaaaagatttactaactgcagcatctgagaaaattattgcccacctaaaagat
ttcaatgaagaccaaaagaaagcaatagaaactgcatatgccatggtgagacactcccca
gcagtagccaagatctgtctgattcatggaccacccgggacaggaaaatcgaaaaccatt
gtgggcctcctgtaccgcctgctgacagagaggaggggactttcagatgagaactccaat
gccaaaatcaaacaaaaccgtgtccttgtgtgtgcgccttccaatgcagctgttgatgaa
cttatgaaaaaaattatccttcaattcaaagggaagtgtaaagacaagaagaatcctttg
ggaaactgtggagatataaatttactacgtctaggtccagaaaagtctattaatgctgag
gtcctaaaattcagtttggacagccaagttaaccacagaatgaaaaaagaattaccttct
catattcaggagatgcatagaagaaaggaatttctagatcatcaactagatgaactttcc
cgccagcgtgctttatgccgaggtggaagggaactacagaggcaagaattagatgaaaaa
attgccagagtttcaaaagaaaggcaggagcttgcttctaaagttaaagaggttcaagga
cgcccacaaaagacacagaacaccatcatcttagagtcccacatcatctgctgcacactg
agcacgagtggtggtttgctgcttgaggctgctttccgtgggcaagggggtgtccccttt
agttgcgtcattgttgatgaggccggacagtcttgtgaagttgaaactcttactccgctc
atccatcgttgcaacaagctcatcctcgtaggagatcctaagcagctccctcccacagtc
atttctgtgaaggcccaggagtatggctatgaccagtcgatgatggcccgcttctacaaa
cttctggaagagaacgtgaagcacaacgtgattggcagactgcctgtcttacagctcacc
gttcagtacaggatgcacccagacatatgtctcttcccttctaattacgtttataacagg
aacttgaaaacaaatagaatcacagaggccattcggtgctcatctgactggccatttcag
ccctacctcgtgtttgatgttggagatggttcagaaaagcgggataatgactcatatgta
aatgttcaagaaataaaactggtaatggaactagttaaacttatgaaagacaaaaaaagg
gattttacttaccgaaacgttggcataataacccattacaaggctcagaagatgatgatt
cagaaggatttggacaaagagtttgatagaaaagggccagcagaagtagataccgtggat
ggcttccagggtcgtcagaaagattgtgttattgttacatgtgtcagagcaaatgccatg
caaggttcaattgggtttctggcaagtttgcagagattgaatgtcaccatcacacgagcc
aagtacagcctcttcatcctgggacatttgaggaccctgatggaaaactgtcattggaat
cagctgattcaggatgcacagaagcgtggtgccattgttaagacttgggacaaaaactat
agacaagatgcagtgaagattctgaaactcaagcccgtactgcagagaagtctgactcac
cctcctgctatcgccccagaggtgtccagaccccagggcggagtgcccagcaacaagcta
gacagtgaatttgccaagatgtctattgcttcttccctgtacccctcaccctctgactcc
aaagaagccactgtcactgttactgcaaatgaccctgaaaggccacccattcaggactgg
cttcgggacccacgactacttaggaggatgggcttgggctgtgaagccaaagggaaatgc
ctcagtgagctgcagccctcgagcccccagtatcccggagcagcgcctctctctggagag
ccaggctcccccggaaggcaccaggatccgaccagtatcgggcagcagccccccgccaag
ggagctgctgtgaacaaccacagacctcacgcgcagtgcgaccctccagctgctagtacc
gatgcttccacgagtaagagaaaatgtgcccaggaaggggaggcagtcagccacaggagg
gagaccagggccttccctgagggggatcaggagacgtgtggctctctgagccaccacaca
aagaggaactcaggctgggacgagagggggctggaggaggaggacagtagcttgaagaag
aggaagctttcatag
DBGET
integrated database retrieval system
