Delphinus delphis (saddleback dolphin): 132432111
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Entry
132432111 CDS
T11117
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ddp Delphinus delphis (saddleback dolphin)
Pathway
ddp00270
Cysteine and methionine metabolism
ddp00480
Glutathione metabolism
ddp01100
Metabolic pathways
ddp01240
Biosynthesis of cofactors
ddp04216
Ferroptosis
Module
ddp_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ddp00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
132432111 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
132432111 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
132432111 (GCLC)
Enzymes [BR:
ddp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
132432111 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
132432111
NCBI-ProteinID:
XP_059878038
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Position
10:complement(41184209..41222615)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETQRHADHVRLHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENRKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTKHKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGLFYFRKDICKGGNAMVDGRNKTTGSTEPAAEEYALMTIDTIINGKEGMFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LLLKCNQIANELCECPELLGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctactgtcccagggctcgccactgagctgggaggagacccagcgccacgcggac
cacgtgcggctgcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtatcttttgatcat
gaaaatagaaaagcccaactggtactgtctggagaggaacttcttgaaactctgcaagaa
aagggggaaaggacaaacccaaaccaccctaccctttggagaccagagtatgggagctac
atgatcgaggggacacctggccagccgtacggagggaccatgtctgagttcaacaccgtc
gaggacaacatgaggaagcgccgcaaggaagcgacatctctgctgggggaaaaccaggcc
ctctgcacaatcacttcgtttcccagattaggctgccctgggttcacactgcccgagttc
aagcccaacccagtggaaggaggagcttccaagtccctcttctttcctgatgaagcgata
aacaagcacccgcgcttcagtaccctcaccaggaacatccggcacagaagaggagaaaag
gttgtcatcaacgtcccaatatttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttctaagcccgaccacatttacatggatgct
atgggctttgggatgggcaattgctgtctgcaggtaacgttccaagcctgcagcatatct
gaggccagatacctttatgatcagttggccactatctgcccaattgtcatggctttgagc
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccgctgaagaacaac
cactataggatcagtaagtcccgatatgattcaatagacagttacttatctgagtgcggt
gagaaatataatgacatcgacctgacgaaacacaaagaaatctatgaacagctgttgcag
gaaggcatcgatcatctcctggcccagcacgtggctcatctcttcattagagacccgcta
actctgttcgaagagaaaatccacctggacgatgccaacgagtccgaccattttgagaat
attcagtccacaaattggcagacaatgcgatttaaacctcctcctccaaactccgacatt
ggatggagagtggaattccggcccatggaggttcagttgacagacttcgagaactccgcg
tacgtggtgttcgtggtgctgctcaccagggtgatcctttcctacaaactggactttctc
atcccgctgtcaaaggttgatgagaacatgaaagtagcacagaagcgagatgccgtcctg
cagggattgttttatttcagaaaagatatttgcaaaggtggcaacgccatggtggacggc
cgcaacaagaccacgggcagcaccgagccagcagccgaggagtacgcactcatgaccatc
gacaccatcatcaacggcaaggaaggcatgttccccgggctgatccccatcctgaactct
tacttggaaaacatggaggtggacgtggacaccagatgcagtattctgaactacctgaag
ctgattaagaagagagcatccggagaattaatgacagttgccagatggatgagggagttc
atcgcaaaccatccagactacaagcaagacagtgtaataactgacgagatgaactacagc
cttcttttaaagtgtaaccaaatcgcaaatgaattatgtgagtgcccagagttacttgga
ccagcgtttaggaaagtaaagtacagtggcagtaaaactgactcttccaactag
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