KEGG   Delphinus delphis (saddleback dolphin): 132438124
Entry
132438124         CDS       T11117                                 
Symbol
MAPK3
Name
(RefSeq) mitogen-activated protein kinase 3
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
ddp  Delphinus delphis (saddleback dolphin)
Pathway
ddp01521  EGFR tyrosine kinase inhibitor resistance
ddp01522  Endocrine resistance
ddp01524  Platinum drug resistance
ddp04010  MAPK signaling pathway
ddp04012  ErbB signaling pathway
ddp04014  Ras signaling pathway
ddp04015  Rap1 signaling pathway
ddp04022  cGMP-PKG signaling pathway
ddp04024  cAMP signaling pathway
ddp04062  Chemokine signaling pathway
ddp04066  HIF-1 signaling pathway
ddp04068  FoxO signaling pathway
ddp04071  Sphingolipid signaling pathway
ddp04072  Phospholipase D signaling pathway
ddp04114  Oocyte meiosis
ddp04140  Autophagy - animal
ddp04148  Efferocytosis
ddp04150  mTOR signaling pathway
ddp04151  PI3K-Akt signaling pathway
ddp04210  Apoptosis
ddp04218  Cellular senescence
ddp04261  Adrenergic signaling in cardiomyocytes
ddp04270  Vascular smooth muscle contraction
ddp04350  TGF-beta signaling pathway
ddp04360  Axon guidance
ddp04370  VEGF signaling pathway
ddp04371  Apelin signaling pathway
ddp04380  Osteoclast differentiation
ddp04510  Focal adhesion
ddp04517  IgSF CAM signaling
ddp04520  Adherens junction
ddp04540  Gap junction
ddp04550  Signaling pathways regulating pluripotency of stem cells
ddp04611  Platelet activation
ddp04613  Neutrophil extracellular trap formation
ddp04620  Toll-like receptor signaling pathway
ddp04621  NOD-like receptor signaling pathway
ddp04625  C-type lectin receptor signaling pathway
ddp04650  Natural killer cell mediated cytotoxicity
ddp04657  IL-17 signaling pathway
ddp04658  Th1 and Th2 cell differentiation
ddp04659  Th17 cell differentiation
ddp04660  T cell receptor signaling pathway
ddp04662  B cell receptor signaling pathway
ddp04664  Fc epsilon RI signaling pathway
ddp04666  Fc gamma R-mediated phagocytosis
ddp04668  TNF signaling pathway
ddp04713  Circadian entrainment
ddp04720  Long-term potentiation
ddp04722  Neurotrophin signaling pathway
ddp04723  Retrograde endocannabinoid signaling
ddp04724  Glutamatergic synapse
ddp04725  Cholinergic synapse
ddp04726  Serotonergic synapse
ddp04730  Long-term depression
ddp04810  Regulation of actin cytoskeleton
ddp04910  Insulin signaling pathway
ddp04912  GnRH signaling pathway
ddp04914  Progesterone-mediated oocyte maturation
ddp04915  Estrogen signaling pathway
ddp04916  Melanogenesis
ddp04917  Prolactin signaling pathway
ddp04919  Thyroid hormone signaling pathway
ddp04921  Oxytocin signaling pathway
ddp04926  Relaxin signaling pathway
ddp04928  Parathyroid hormone synthesis, secretion and action
ddp04929  GnRH secretion
ddp04930  Type II diabetes mellitus
ddp04933  AGE-RAGE signaling pathway in diabetic complications
ddp04934  Cushing syndrome
ddp04935  Growth hormone synthesis, secretion and action
ddp04960  Aldosterone-regulated sodium reabsorption
ddp05010  Alzheimer disease
ddp05020  Prion disease
ddp05022  Pathways of neurodegeneration - multiple diseases
ddp05034  Alcoholism
ddp05132  Salmonella infection
ddp05133  Pertussis
ddp05135  Yersinia infection
ddp05140  Leishmaniasis
ddp05142  Chagas disease
ddp05145  Toxoplasmosis
ddp05152  Tuberculosis
ddp05160  Hepatitis C
ddp05161  Hepatitis B
ddp05163  Human cytomegalovirus infection
ddp05164  Influenza A
ddp05165  Human papillomavirus infection
ddp05166  Human T-cell leukemia virus 1 infection
ddp05167  Kaposi sarcoma-associated herpesvirus infection
ddp05170  Human immunodeficiency virus 1 infection
ddp05171  Coronavirus disease - COVID-19
ddp05200  Pathways in cancer
ddp05203  Viral carcinogenesis
ddp05205  Proteoglycans in cancer
ddp05206  MicroRNAs in cancer
ddp05207  Chemical carcinogenesis - receptor activation
ddp05208  Chemical carcinogenesis - reactive oxygen species
ddp05210  Colorectal cancer
ddp05211  Renal cell carcinoma
ddp05212  Pancreatic cancer
ddp05213  Endometrial cancer
ddp05214  Glioma
ddp05215  Prostate cancer
ddp05216  Thyroid cancer
ddp05218  Melanoma
ddp05219  Bladder cancer
ddp05220  Chronic myeloid leukemia
ddp05221  Acute myeloid leukemia
ddp05223  Non-small cell lung cancer
ddp05224  Breast cancer
ddp05225  Hepatocellular carcinoma
ddp05226  Gastric cancer
ddp05230  Central carbon metabolism in cancer
ddp05231  Choline metabolism in cancer
ddp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ddp05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ddp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132438124 (MAPK3)
   04012 ErbB signaling pathway
    132438124 (MAPK3)
   04014 Ras signaling pathway
    132438124 (MAPK3)
   04015 Rap1 signaling pathway
    132438124 (MAPK3)
   04350 TGF-beta signaling pathway
    132438124 (MAPK3)
   04370 VEGF signaling pathway
    132438124 (MAPK3)
   04371 Apelin signaling pathway
    132438124 (MAPK3)
   04668 TNF signaling pathway
    132438124 (MAPK3)
   04066 HIF-1 signaling pathway
    132438124 (MAPK3)
   04068 FoxO signaling pathway
    132438124 (MAPK3)
   04072 Phospholipase D signaling pathway
    132438124 (MAPK3)
   04071 Sphingolipid signaling pathway
    132438124 (MAPK3)
   04024 cAMP signaling pathway
    132438124 (MAPK3)
   04022 cGMP-PKG signaling pathway
    132438124 (MAPK3)
   04151 PI3K-Akt signaling pathway
    132438124 (MAPK3)
   04150 mTOR signaling pathway
    132438124 (MAPK3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    132438124 (MAPK3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    132438124 (MAPK3)
   04148 Efferocytosis
    132438124 (MAPK3)
  09143 Cell growth and death
   04114 Oocyte meiosis
    132438124 (MAPK3)
   04210 Apoptosis
    132438124 (MAPK3)
   04218 Cellular senescence
    132438124 (MAPK3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132438124 (MAPK3)
   04520 Adherens junction
    132438124 (MAPK3)
   04540 Gap junction
    132438124 (MAPK3)
   04550 Signaling pathways regulating pluripotency of stem cells
    132438124 (MAPK3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    132438124 (MAPK3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    132438124 (MAPK3)
   04613 Neutrophil extracellular trap formation
    132438124 (MAPK3)
   04620 Toll-like receptor signaling pathway
    132438124 (MAPK3)
   04621 NOD-like receptor signaling pathway
    132438124 (MAPK3)
   04625 C-type lectin receptor signaling pathway
    132438124 (MAPK3)
   04650 Natural killer cell mediated cytotoxicity
    132438124 (MAPK3)
   04660 T cell receptor signaling pathway
    132438124 (MAPK3)
   04658 Th1 and Th2 cell differentiation
    132438124 (MAPK3)
   04659 Th17 cell differentiation
    132438124 (MAPK3)
   04657 IL-17 signaling pathway
    132438124 (MAPK3)
   04662 B cell receptor signaling pathway
    132438124 (MAPK3)
   04664 Fc epsilon RI signaling pathway
    132438124 (MAPK3)
   04666 Fc gamma R-mediated phagocytosis
    132438124 (MAPK3)
   04062 Chemokine signaling pathway
    132438124 (MAPK3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    132438124 (MAPK3)
   04929 GnRH secretion
    132438124 (MAPK3)
   04912 GnRH signaling pathway
    132438124 (MAPK3)
   04915 Estrogen signaling pathway
    132438124 (MAPK3)
   04914 Progesterone-mediated oocyte maturation
    132438124 (MAPK3)
   04917 Prolactin signaling pathway
    132438124 (MAPK3)
   04921 Oxytocin signaling pathway
    132438124 (MAPK3)
   04926 Relaxin signaling pathway
    132438124 (MAPK3)
   04935 Growth hormone synthesis, secretion and action
    132438124 (MAPK3)
   04919 Thyroid hormone signaling pathway
    132438124 (MAPK3)
   04928 Parathyroid hormone synthesis, secretion and action
    132438124 (MAPK3)
   04916 Melanogenesis
    132438124 (MAPK3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    132438124 (MAPK3)
   04270 Vascular smooth muscle contraction
    132438124 (MAPK3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    132438124 (MAPK3)
  09156 Nervous system
   04724 Glutamatergic synapse
    132438124 (MAPK3)
   04725 Cholinergic synapse
    132438124 (MAPK3)
   04726 Serotonergic synapse
    132438124 (MAPK3)
   04720 Long-term potentiation
    132438124 (MAPK3)
   04730 Long-term depression
    132438124 (MAPK3)
   04723 Retrograde endocannabinoid signaling
    132438124 (MAPK3)
   04722 Neurotrophin signaling pathway
    132438124 (MAPK3)
  09158 Development and regeneration
   04360 Axon guidance
    132438124 (MAPK3)
   04380 Osteoclast differentiation
    132438124 (MAPK3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    132438124 (MAPK3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132438124 (MAPK3)
   05206 MicroRNAs in cancer
    132438124 (MAPK3)
   05205 Proteoglycans in cancer
    132438124 (MAPK3)
   05207 Chemical carcinogenesis - receptor activation
    132438124 (MAPK3)
   05208 Chemical carcinogenesis - reactive oxygen species
    132438124 (MAPK3)
   05203 Viral carcinogenesis
    132438124 (MAPK3)
   05230 Central carbon metabolism in cancer
    132438124 (MAPK3)
   05231 Choline metabolism in cancer
    132438124 (MAPK3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132438124 (MAPK3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    132438124 (MAPK3)
   05212 Pancreatic cancer
    132438124 (MAPK3)
   05225 Hepatocellular carcinoma
    132438124 (MAPK3)
   05226 Gastric cancer
    132438124 (MAPK3)
   05214 Glioma
    132438124 (MAPK3)
   05216 Thyroid cancer
    132438124 (MAPK3)
   05221 Acute myeloid leukemia
    132438124 (MAPK3)
   05220 Chronic myeloid leukemia
    132438124 (MAPK3)
   05218 Melanoma
    132438124 (MAPK3)
   05211 Renal cell carcinoma
    132438124 (MAPK3)
   05219 Bladder cancer
    132438124 (MAPK3)
   05215 Prostate cancer
    132438124 (MAPK3)
   05213 Endometrial cancer
    132438124 (MAPK3)
   05224 Breast cancer
    132438124 (MAPK3)
   05223 Non-small cell lung cancer
    132438124 (MAPK3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    132438124 (MAPK3)
   05170 Human immunodeficiency virus 1 infection
    132438124 (MAPK3)
   05161 Hepatitis B
    132438124 (MAPK3)
   05160 Hepatitis C
    132438124 (MAPK3)
   05171 Coronavirus disease - COVID-19
    132438124 (MAPK3)
   05164 Influenza A
    132438124 (MAPK3)
   05163 Human cytomegalovirus infection
    132438124 (MAPK3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132438124 (MAPK3)
   05165 Human papillomavirus infection
    132438124 (MAPK3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132438124 (MAPK3)
   05135 Yersinia infection
    132438124 (MAPK3)
   05133 Pertussis
    132438124 (MAPK3)
   05152 Tuberculosis
    132438124 (MAPK3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132438124 (MAPK3)
   05140 Leishmaniasis
    132438124 (MAPK3)
   05142 Chagas disease
    132438124 (MAPK3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    132438124 (MAPK3)
   05020 Prion disease
    132438124 (MAPK3)
   05022 Pathways of neurodegeneration - multiple diseases
    132438124 (MAPK3)
  09165 Substance dependence
   05034 Alcoholism
    132438124 (MAPK3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132438124 (MAPK3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    132438124 (MAPK3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    132438124 (MAPK3)
   04934 Cushing syndrome
    132438124 (MAPK3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    132438124 (MAPK3)
   01524 Platinum drug resistance
    132438124 (MAPK3)
   01522 Endocrine resistance
    132438124 (MAPK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ddp01001]
    132438124 (MAPK3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ddp03036]
    132438124 (MAPK3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ddp04147]
    132438124 (MAPK3)
Enzymes [BR:ddp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     132438124 (MAPK3)
Protein kinases [BR:ddp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   132438124 (MAPK3)
Chromosome and associated proteins [BR:ddp03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     132438124 (MAPK3)
Exosome [BR:ddp04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   132438124 (MAPK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 132438124
NCBI-ProteinID: XP_059888012
LinkDB
Position
15:71697314..71703468
AA seq 325 aa
MVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEA
MRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI
NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI
LAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAK
LFPKSDPKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDD
LPKERLKELIFQETARFQPGVLEAP
NT seq 978 nt   +upstreamnt  +downstreamnt
atggtcagctcagcttacgaccacgtgcgcaagactcgagtggccatcaagaaaatcagc
ccctttgagcatcagacctactgccagcgtacgttgcgagagatccagatcttgctgcgc
ttccgccacgagaacgtcatcggcatccgagacattctgcgggcacccaccctggaagcc
atgagggatgtctacattgtgcaagacctgatggagacagacctgtacaagttgcttaaa
agccagcagctgagcaacgaccacatctgctacttcctctaccaaatcctgcggggcctc
aagtatatccattccgccaacgtgctccaccgggatttaaagccctccaacctgctcatc
aacaccacctgcgacctgaagatctgtgattttggtcttgcccggattgccgatcctgag
cacgaccacactggctttctgacggaatacgtggctacacgctggtaccgggccccagag
atcatgcttaactccaagggctacaccaagtccatcgacatctggtctgtgggctgcatt
ctggctgagatgctctccaaccggcccatcttcccgggcaagcactacctggaccagctc
aaccacattctgggtatcctgggctccccctcccaggaggacctgaattgtatcatcaac
atgaaggcccgaaactacctacagtctctaccctccaagaccaaggtggcctgggccaag
ctttttcccaagtcggaccccaaagctcttgacctgctggaccggatgttgacctttaac
cctaacaaacggatcacagtggaagaagcactggctcacccctacctggagcagtactac
gacccaacagatgagccagtggccgaggaacctttcaccttcgacatggagctggatgat
ctacccaaggagcggctgaaggagctcatcttccaggagacagcccgtttccagcctggg
gtgctggaggccccctaa

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