Candidatus Desulfobacillus denitrificans: DSYM_22850
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Entry
DSYM_22850 CDS
T07109
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ddz
Candidatus Desulfobacillus denitrificans
Pathway
ddz00290
Valine, leucine and isoleucine biosynthesis
ddz00620
Pyruvate metabolism
ddz01100
Metabolic pathways
ddz01110
Biosynthesis of secondary metabolites
ddz01210
2-Oxocarboxylic acid metabolism
ddz01230
Biosynthesis of amino acids
Module
ddz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ddz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DSYM_22850
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DSYM_22850
Enzymes [BR:
ddz01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DSYM_22850
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
NADH_4Fe-4S
BIg21
Motif
Other DBs
NCBI-ProteinID:
BBO21586
UniProt:
A0A809RZH4
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All DBs
Position
complement(2325223..2326758)
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AA seq
511 aa
AA seq
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MKDHLVIFDTTLRDGEQSPGASMTREEKLRVARQLERMRVDVIEAGFAAASPGDFDAIRS
IAETVKDSTICSLARANENDIRRAGEAIRPANSGRIHTFIATSPIHMEKKLRMTPDQVVE
AAVKAVTLARNLSDDVEFSAEDAVRSEFDFLCRVFEAAIKAGARTINVPDTVGYSIPSVW
GERMRALIERVPGSDKVVWSTHCHNDLGMAVANSLAAVMAGARQVECTINGLGERAGNAS
LEEVVMAVKTRSDLFSVQTRIDTTQIVPASKLVSSITGYPVQPNKAIVGANAFAHESGIH
QDGVLKHRETYEIMRAQDVGWTQNKLVLGKHSGRNAFKSRLAELGVAVESEEHLNAAFAR
FKELADKKHEIFDEDLQALMSDEAVTPEQEFFKLVGLRVTSETGETPHAMITLSAGGGER
KSEADGDGPVDACFKAVEHIAESRPELLLFSVNSITGGTDAQGEVTVRLAKDGRVVNGQG
ADTDIVVASVKAYINALNKLVSKPEKVNPQV
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaccatttggtgattttcgacacgaccttgcgcgacggcgagcaaagcccgggc
gcctccatgacccgggaagaaaagctgcgcgtggcacgccaactggagcgcatgcgggtg
gacgtgatcgaggccggcttcgccgctgcctcgcccggcgatttcgatgccatccgcagc
atcgcggagacggtgaaggattccacgatctgctcgctggcgcgcgccaacgagaatgac
atccgccgcgccggcgaggccatccggccggccaactcgggccgcatccatacgttcatt
gccaccagccccattcacatggaaaagaagctgcgcatgacaccggaccaggtggtcgag
gccgcggtgaaggcggtgacgctggcgcgcaacttgtcggatgacgtggagttttccgcc
gaggatgccgttcgctccgaattcgattttctctgccgcgttttcgaggccgccatcaag
gccggcgccaggacgatcaacgtgcccgatacggtcggctacagcataccgtcggtgtgg
ggcgagcgcatgcgcgcactgatcgagcgcgtgcccgggtcggacaaggtggtgtggtcg
acccactgccataacgacctgggcatggcggtggcgaattcgctcgccgcggtcatggcg
ggcgcacgccaggtggaatgcacgatcaacggcctcggcgagcgggcgggcaatgcctca
ttggaagaagtggtcatggcggtgaagacgcgcagcgaccttttctccgtccagacgcgc
atcgacacgacccagatcgttccggcctcgaaactggtctcgagcatcaccggctatccg
gtgcagccgaacaaggccatcgtcggcgccaacgccttcgcccacgaatcgggcatccat
caggacggcgtgctcaagcaccgcgagacctacgagatcatgcgcgcccaggatgtcggc
tggacgcagaacaagctggtgctgggcaagcattccggccgcaatgccttcaaatcgcga
ttggcggagctcggcgtcgcggtcgagtcggaggaacatttgaatgccgctttcgcccgt
ttcaaggagttggcggacaagaagcatgaaatcttcgacgaagatctgcaggcgctcatg
tccgacgaggcggtgacgccggagcaagagtttttcaagctggtggggctgcgcgtgacg
tcggagaccggcgagacgccgcacgccatgatcacgctgtccgccggtggcggcgaaagg
aaatccgaggccgatggcgatggtccggtggatgcctgcttcaaggcggtcgaacatatc
gccgagagtcgcccggagctgttgctgttctcggtgaatagcatcaccggcggcaccgac
gcccagggcgaggtcaccgtgcgtctggccaaggacggccgtgtggtcaatggccagggt
gcggatacggatatcgtcgtcgcctccgtcaaggcctacatcaatgccctgaacaagctg
gtttccaagccggaaaaggtgaacccgcaggtctga
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