Candidatus Doolittlea endobia: MHIR_DE00116
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Entry
MHIR_DE00116 CDS
T04480
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
den
Candidatus Doolittlea endobia
Pathway
den00300
Lysine biosynthesis
den00550
Peptidoglycan biosynthesis
den01100
Metabolic pathways
den01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
den00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MHIR_DE00116 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MHIR_DE00116 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MHIR_DE00116 (murF)
Enzymes [BR:
den01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MHIR_DE00116 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CUX96457
UniProt:
A0A143WSF7
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All DBs
Position
I:123008..124375
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AA seq
455 aa
AA seq
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MISCTLSEIATILNAERVGIDDIIETIVTDSRAPAATQKRLFVALKGEKFDAHDFAEQAV
AGGVAALLVNQRLPLDVPQLVVADTRRALGQLGAWVRQQVPARVVALTGSSGKTSVKEMT
TAILRRCGRVLATESNFNNDIGVSLTLLRLTPAYDFAVIELGASHLGDIAWTTALVRPET
ALVNNLSVAHLAGFGSLSGIAQAKGEIFSGLPANGRGILNADSHNWQHWQQVLGQKAVWR
FTVQADDSADFFASGIESDQQGVRFILHSPLGECPVRLPLLGRHHVANALAASALALSVG
AELPAVAAGLAQSQAIPGRLFPIELSAGRLLLDDTYNANVGSMTAAVQILAKMPGYRVMV
VGDMSELGEQTAKYHRQVGKAVALAGINKVLSVGNLSRLISDSSDRGEHFQDKTALTNQL
AQLMSEQAIITILVKGSRSAAMEQVVRALQEQASC
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgatctcctgtacacttagcgaaatagcgacaatacttaatgctgaacgagtgggcatt
gatgacatcatcgagaccattgtcaccgattcgcgggcaccagctgcgacgcagaaacgt
ttatttgtcgctctgaagggcgagaaatttgatgcccatgattttgccgagcaagccgtt
gccggcggtgtcgcagcgttgttggttaaccaacgtctgccgctagatgtaccacagttg
gttgtcgccgacacccggcgtgcgcttggccaattaggcgcctgggtgcgtcagcaagtc
ccagcgcgggtagtagccctgacggggtcttccggaaaaacatcggttaaagaaatgacc
accgccatcttgcggcgatgcgggcgggtactggcgacagaaagtaattttaataacgat
attggcgtatcactgacgttgttacgtttgacgccggcatatgattttgcggttatcgag
ctgggggctagtcatcttggtgacatcgcttggacaaccgctttagtacgtccggaaacc
gcgctggtaaacaatctttccgtggctcacttagccgggttcggatcactatcgggcata
gcgcaggctaaaggcgaaattttttccggcctgccggctaatggacgcgggattctgaat
gctgacagccataattggcagcactggcaacaagtactaggccaaaaggcggtttggcgt
ttcactgtacaagccgacgacagcgcggatttttttgccagtggtattgaaagtgaccag
cagggtgtgaggttcattttgcacagtccattgggtgaatgcccagttcggttgcctctg
ctaggcagacatcatgttgcaaatgcgctggctgccagcgcattggcactatcggtgggg
gcggagttgccggcggttgctgccggtctagcgcaatcgcaggccataccaggacggttg
ttccctattgagctcagtgcaggccgtttgctactggacgatacctataacgctaatgtc
gggtccatgacagccgccgtgcagatactggcaaaaatgcctggctacagggtaatggta
gtcggtgatatgagcgagctaggggaacaaacggcgaaataccatcgacaagttggcaaa
gccgtcgccttagccggtatcaacaaagttttaagtgtcggtaaccttagccgacttatt
agtgatagcagcgatcggggagaacattttcaggataaaaccgcactgaccaaccaacta
gcgcagctgatgtccgaacaggctatcataaccatattagtaaagggttcacgtagtgcc
gcaatggagcaggtggtgcgcgctttacaggagcaggcatcgtgttag
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