| Entry |
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| Name |
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, mitochondrial isoform X1
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| KO |
| K00161 | pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] |
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| Organism |
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| Pathway |
| der01210 | 2-Oxocarboxylic acid metabolism |
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| Module |
| der_M00307 | Pyruvate oxidation, pyruvate => acetyl-CoA |
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| Brite |
KEGG Orthology (KO) [BR:der00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
6551104
00020 Citrate cycle (TCA cycle)
6551104
00620 Pyruvate metabolism
6551104
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
6551104
Enzymes [BR:der01000]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
6551104
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
440 aa
MLRTLSRVSELPIIVKQLQKRYHNNNNIISGCRIFSNNNNSSNTDIIRNGRYSSSFFGLF
QNAAQAGVSKTNNYATEATIQVNRPFKLHRLDEGPATEVKLTKDQALKYYTQMQTIRRLE
TAAGNLYKEKIIRGFCHLYSGQEACAVGMKAAMRDVDNIISAYRVHGWTYLMGVSPSGVL
AELTGVQGGCARGKGGSMHMYAPNFYGGNGIVGAQVPLGAGVGLACKYKGNGGMCLALYG
DGAANQGQVFEAYNMAYLWKLPVIFVCENNNYGMGTSSERASCNTDYYTRGDALPGIWVD
GMDVLAVRSATEFAINYVNTHGPLVMETNTYRYSGHSMSDPGTSYRTREEIQEVRQKRDP
ITSFKELCIELGLITTDEVKAIDLKVRKEVDEATAFAKSDAELGVSHLWTDVYSNNLEPK
LRGTIAYDIDHIQERKGVNH |
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| NT seq |
1323 nt +upstreamnt +downstreamnt
atgttgcgtactctgtcacgcgttagcgaattgcccattattgttaagcaactgcaaaaa
cgttaccataacaacaacaacatcatcagtggatgtcggatatttagcaacaacaacaac
agcagcaacaccgatatcatcaggaatgggagatattcatcgtcgtttttcggtttattc
cagaatgcagcccaagcaggtgtttcaaaaaccaacaattatgccacggaagccaccatt
caagtgaatcggcccttcaagctgcaccgcctggacgaaggacccgccacggaagtgaaa
ctgaccaaggatcaggccctcaagtactacacacagatgcagacgatccgccggttggag
acggccgccggtaatctgtacaaggagaagatcatccgtggcttctgtcatctgtattcc
ggccaggaggcctgcgccgttggcatgaaggcggcgatgcgggatgtggacaacatcata
tcggcctaccgtgtccacggatggacctacctgatgggtgtctcacccagcggcgtactg
gctgagctcaccggtgtccagggtggctgtgcccgcggcaagggtggctccatgcacatg
tacgcaccgaacttctacggtggtaacggcatcgtgggtgcccaagtacctttgggcgcc
ggcgttggcttggcctgcaagtacaagggcaatggcggcatgtgcctggccctctacggt
gatggtgccgccaaccagggacaggtgttcgaggcctacaacatggcctacctgtggaaa
ctgcctgtgatctttgtctgcgagaacaacaactacggaatgggcaccagctcagagcgt
gcgtcctgcaacactgactactatactcgcggcgacgctttgcccggaatctgggtggac
ggcatggatgtgctggccgtgcgcagcgccaccgagttcgccatcaactatgtgaacact
cacggacctttggtgatggagacgaacacgtaccgatactctggccactccatgtccgat
ccgggcacatcgtaccgcacacgcgaggagatccaggaggtgcgccagaagcgcgatccc
atcacgtccttcaaggagctgtgcatcgagctgggtctgatcaccaccgatgaagtcaag
gccatcgatctgaaggtacgcaaggaggtcgacgaggccactgcctttgccaaatccgac
gccgagctgggcgtgagccacctctggacggacgtgtactccaacaacctggagcccaaa
ctgcgcggcaccatcgcctacgatattgatcacatccaagagcgcaagggcgtcaatcac
taa |
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