Dehalococcoides mccartyi 195: DET0825
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Entry
DET0825 CDS
T00223
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
det
Dehalococcoides mccartyi 195
Pathway
det00290
Valine, leucine and isoleucine biosynthesis
det00620
Pyruvate metabolism
det01100
Metabolic pathways
det01110
Biosynthesis of secondary metabolites
det01210
2-Oxocarboxylic acid metabolism
det01230
Biosynthesis of amino acids
Module
det_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
det00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DET0825
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DET0825
Enzymes [BR:
det01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DET0825
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Asparaginase_C
PEP_mutase
Bromo_TP
TetR_C_31
Motif
Other DBs
NCBI-ProteinID:
AAW39940
UniProt:
Q3Z897
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Position
complement(752778..754379)
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AA seq
533 aa
AA seq
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MQVKLYDTTLRDGSQREGISFTVADKLKIAQKLDELGIHYIEGGWPGSNPKDSEFFVQVK
SLKLKNAKMVAFGSTRRPKVKAEADATLKQLVEAGTEYVTLVGKSSARQVTQVLETTLEE
NLAMITDSIEYLRSKCIKVFLDAEHFFDGYKDNPEYSIQVLQAAEKAGAEGVVLCDTNGG
SLPEEIAEAVEAVTKSVNICVGIHSHNDTEMAVANSIAALKAGASQIQGTINGFGERCGN
ANMCSIIPILKLKMGIDCITDSQLKLLTDTSHYISELANLVSEPFLPYVGASAFSHKAGL
HVSGLSKWSGSYQHIEPELVGNRQRLLVSELAGRSNIVQRAKAIGINLTSDSKEVKDLLQ
QVKKMESMGFQYENAEASFDLLVNRTQAGYAAPFELIDFMVVVEKQRRPSAMRSQDEMMA
EGIVKVRVDGEVMHTVAEGNGPINALDAALRKGLCQFYPELSSVHLSDYKVRILEQTSGT
DALVRVLIESTDGESTWHTVGASPNIIEASWLALSDSFEYWLITKKCKNCKKQ
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
gtgcaagtaaaactatatgatactactttaagagacggttctcagcgtgaaggaatttcc
tttacggtagctgataagcttaagattgcccagaaactggatgaactgggcatacactat
attgagggcggctggccgggttcaaaccccaaagacagtgaattttttgttcaggtaaag
tccctcaagctgaaaaatgccaaaatggtggctttcggctctacccgccgccccaaagtt
aaagccgaagcagatgcaaccctgaagcagctggttgaggcaggtacggaatatgttaca
ttggtcggcaagagttccgccagacaggtgacccaggtgctggaaaccactctggaagaa
aatctggccatgattactgattccattgaatacctgcgttcaaaatgcataaaggttttt
ttggacgccgaacacttttttgacggctacaaagacaaccccgaatactccatacaggtt
ttgcaggcggccgaaaaggccggagctgaaggcgtggtgctttgcgataccaacggaggc
agtctgcccgaagaaatagccgaagccgtagaagcggtaaccaagtcggtaaatatctgc
gtgggtattcactctcataatgacacggaaatggccgtagctaacagtatagccgctctc
aaggccggtgccagccagattcagggtacgataaatggttttggtgaaagatgcggcaat
gccaacatgtgctccataatacccattttaaagctgaaaatgggtatagactgcataact
gacagccagttgaagctgctgaccgatacttcccattatataagcgaactggcaaatctg
gtttccgaaccgtttttgccgtatgtgggtgccagcgccttttcccacaaagcaggcctg
catgtcagcggcctgagcaagtggtcaggcagttaccagcatatagagccggaactggtg
ggcaaccgccagcgtttattggtatcggaattggcaggccggtcaaacattgtccaaagg
gccaaagctatcggcataaatttgacgtcggactcaaaagaagtcaaagatttgcttcag
caggtcaagaaaatggagagcatgggttttcagtatgaaaatgctgaggcctcttttgat
ttgctggtaaaccgcacccaggcgggttatgcagccccgtttgagcttatagattttatg
gtggtggtagaaaaacagcgccgcccctcagctatgcgcagccaggacgaaatgatggcc
gaagggatagtaaaagtaagggtagacggcgaggttatgcatactgtcgccgaaggcaac
ggccccataaatgcacttgatgccgctttgcgcaaaggactttgccagttttatccggaa
ctttcatctgtccatctttcggattacaaggtgcgtatactggagcagaccagcggtaca
gatgctttggtgagggtgctgattgaatctactgatggtgaaagtacctggcatactgta
ggtgccagcccgaatatcatcgaagccagttggctggctttgtcagacagctttgaatac
tggctgattaccaagaaatgtaaaaactgcaagaaacagtaa
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