Dehalococcoides mccartyi VS: DhcVS_734
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Entry
DhcVS_734 CDS
T01136
Symbol
leuA2
Name
(GenBank) isopropylmalate/homocitrate/citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
dev
Dehalococcoides mccartyi VS
Pathway
dev00290
Valine, leucine and isoleucine biosynthesis
dev00620
Pyruvate metabolism
dev01100
Metabolic pathways
dev01110
Biosynthesis of secondary metabolites
dev01210
2-Oxocarboxylic acid metabolism
dev01230
Biosynthesis of amino acids
Module
dev_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
dev00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DhcVS_734 (leuA2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DhcVS_734 (leuA2)
Enzymes [BR:
dev01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DhcVS_734 (leuA2)
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Paralog
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Lipoprotein_2
Motif
Other DBs
NCBI-ProteinID:
ACZ61866
UniProt:
D2BHR6
LinkDB
All DBs
Position
complement(681747..683264)
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AA seq
505 aa
AA seq
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MDKIKIFDTTLRDGEQAAGASLNAQEKLEIARQLEKLGVDIIEAGFPITSPGDFEAVKLI
AQEVRTTVICGLARAIPADIDRAWEALKEAAHPRIHVFISSSEIHMVHQIKKSREEVMEL
ARTMVARAKSYTDDIEFSPMDASRSDPEFLYKLLEAVIDAGATTLNIPDTVGYAIPSEFG
ELIKGIRQNVPNINKAVISVHCHDDLGMGTANSLAAVKNGARQVECTLNGIGERAGNAAL
EEVVMALRTRSDFFNFETGINTQEIYRSSRLVSALTGFAIQPNKAVVGENAFRHQSGIHQ
DGVIKMAKTFEIMDPKEVGIQASSLVLGKLSGRHAFKQHLTELGFDLNEEDFDRAFKAFK
DLADKKKDVTDRDIEALVAEELRTTVELYHLDRIQVTSGDRGIPTAAVRLTTPNGEAAED
AALGSGPVDAVYKAINRIVNVPNKLTEFSVKSVTAGIDALGEVLIRIESDGVTYTGRGSD
TDIIVASAKAYMNALNRLLRVKNAS
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atggacaaaataaagatttttgataccaccctcagagatggagaacaggctgccggtgcg
tctttgaatgcacaggaaaaactggagatagcccggcagctggaaaaactgggggtggat
atcattgaagcaggttttcccatcacctctcccggtgattttgaagcggtaaagctgata
gcccaggaagtgcgcaccactgtcatctgcggtctggccagagctataccggctgacatt
gaccgtgcctgggaggctttgaaagaagctgcccacccccgaattcatgtgtttatttct
tcatctgaaatacacatggttcaccagataaaaaagagtcgtgaagaagtaatggagctg
gcgcgcactatggttgccagagccaaaagctatactgatgacatagagttttcacctatg
gatgccagccgctctgacccggagtttctttataaactgttggaagcagttatagatgcc
ggggctaccaccctgaatatacctgatactgtgggttacgctatccccagtgagttcggc
gaactcataaagggtatccgccagaatgtgcctaatataaacaaagcggtaataagcgta
cactgccacgatgatttgggtatgggtacagccaattcgctggctgcggttaaaaacggt
gccagacaggtggaatgcaccctgaacggcataggcgaacgtgccggcaatgccgcactg
gaagaagtagtgatggcactgcgcacccggagtgattttttcaattttgaaacaggtata
aacacccaggaaatataccgcagcagccgcctggtcagcgctctgaccggttttgctatt
cagcccaacaaggctgtggtgggtgaaaacgctttccgccaccagtccggtatccaccag
gacggcgttattaaaatggctaaaacttttgagattatggaccccaaagaagtgggtatt
caggcttccagcctggtactgggcaaactttccggccgccacgccttcaaacagcacctg
acagagctgggctttgacctgaacgaagaagattttgaccgcgcattcaaggcctttaaa
gatttggccgataaaaagaaggacgtgactgaccgggacatagaagcgctggttgccgaa
gaactgcggactacagttgagctttatcatttggaccggattcaggttacctccggagac
aggggcatacccactgctgccgtcagactcaccaccccgaacggagaggcagcagaagat
gccgctttgggcagcgggccggtagatgctgtttacaaggccataaaccggatagtaaat
gtacctaacaaactgactgaattttcggttaagtctgttacggccggcattgacgcactg
ggtgaagtgcttatccgtattgagagtgacggggtaacatataccggacgcggatcagat
acggatataatagtagccagtgccaaggcttatatgaacgccttaaaccgtttgctcagg
gtcaagaacgcatcttaa
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