Dorea formicigenerans: NQ560_13370
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Entry
NQ560_13370 CDS
T08666
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
dfm
Dorea formicigenerans
Pathway
dfm00300
Lysine biosynthesis
dfm00550
Peptidoglycan biosynthesis
dfm01100
Metabolic pathways
dfm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
dfm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NQ560_13370
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NQ560_13370
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NQ560_13370
Enzymes [BR:
dfm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NQ560_13370
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UWP19469
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Position
2742195..2743562
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AA seq
455 aa
AA seq
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MKNLTLRNITKACHGEYRGPENLLDKEVAGVTIDSRKVEKDYLFIAIDGERVNAHKFIPD
TIKKGAMCVISHEDLGETDFPYILVESTGQALLDTAKLYRDSFDIKVVGITGSVGKTSTK
EMIASVLSQKYCVHKTLGNFNNEWGLPITIFEMNEKHQVAVLEMGVNHFGEMRRLSSVAS
PDICVITNIGIAHLEFFKTREGILQEKSQMIQDMKTGGSILLNGDDDLLRDMGPVKGVDP
EFFGLGKNCQFYATDVESLGLRGSSCTIHLPSGESFDCIVPLPGAHMVQNALAGTAVGYQ
LGLTPAEIKAGIEGLPSIPGRNNIIQTDKIIILDDCYNANPISMQASLDVLNMAIGRKVA
VLGDMGELGETGKELHYETGAHAGDIGIDLVCGIGELSKELVAGASEHGCEAKWFPAKAD
FLAEMKHLIQPGDNILVKASHGMQFPEIVDELQKF
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaccttactttaagaaatattactaaggcctgccacggagagtaccgggggcct
gaaaatcttttggacaaagaagttgccggtgttacaattgacagccggaaagttgaaaaa
gactatctgttcattgccattgacggtgaacgcgtcaacgctcacaaattcattccagat
accattaaaaaaggcgcaatgtgcgtgatttcccatgaagatcttggcgagacagatttt
ccatatatcctggtagagtctactggccaggcacttcttgatactgcaaagctttatcgt
gattctttcgatattaaggttgtcggaatcacaggaagtgtcggaaagacaagcacaaag
gaaatgattgcttctgtactgtctcagaaatactgtgtacataaaacacttggaaacttc
aacaatgaatgggggcttccaattacaatttttgaaatgaatgaaaagcatcaggtcgct
gttctggaaatgggtgtcaaccactttggtgagatgcgtcgtctttccagcgtagcaagc
ccggatatctgtgtgatcacgaatatcggtatcgcacatttggaatttttcaagacaaga
gaagggattcttcaggaaaaatctcagatgatccaggatatgaagaccggtggttctatt
cttctgaacggagacgatgatctgctccgtgatatgggaccggtcaaaggcgtagatcct
gaatttttcggtcttggaaagaactgccagttctatgcaactgacgtagaatcacttgga
cttcgcggttcttcctgtacgattcatcttccgtccggcgaaagctttgactgcatcgtt
ccacttcctggtgctcacatggtacaaaacgctcttgccggaactgctgtcggctatcaa
cttggacttacaccagcagaaatcaaagccggaattgaaggactgccttcaatccctgga
agaaataatatcattcaaacagataaaatcatcatcttagatgactgctataatgcaaat
ccaatttccatgcaggcttccttagatgttctgaatatggcaatcggacgaaaagtcgct
gttcttggcgacatgggcgaactgggcgagaccggaaaagaactccactacgaaaccggt
gcacatgcaggtgatataggcatcgaccttgtatgcggaattggcgagctttccaaagag
cttgtagccggagcttctgaacatggctgcgaggcaaaatggttccctgcaaaagcagac
tttcttgcagagatgaaacatctgattcaaccaggtgacaatatccttgtgaaagcttca
catggtatgcagttccctgaaatcgtagatgaattacaaaaattttag
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