Desulfoscipio gibsoniae: Desgi_0738
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Entry
Desgi_0738 CDS
T02657
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
dgi
Desulfoscipio gibsoniae
Pathway
dgi00290
Valine, leucine and isoleucine biosynthesis
dgi00620
Pyruvate metabolism
dgi01100
Metabolic pathways
dgi01110
Biosynthesis of secondary metabolites
dgi01210
2-Oxocarboxylic acid metabolism
dgi01230
Biosynthesis of amino acids
Module
dgi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
dgi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Desgi_0738
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Desgi_0738
Enzymes [BR:
dgi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Desgi_0738
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
AGL00293
UniProt:
R4KAS9
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Position
751183..752751
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AA seq
522 aa
AA seq
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MRRLYVFDTTLRDGEQSLGITLNVHEKIEIANQLVKLGVDVIEAGFPASSPGDLESVRTL
ARELKGVIVCGLSRAVEYDIDCCAESLREAEYPRIHTGIAVSPVHMEQKLKLSPDQVVEA
AVAAVKHAKKYVSDVEFYAEDAFRSELPFLARVLEQVIAAGATVVNIPDTVGYATPWEYA
EMVKYVKNHVSNIDKAVVSIHCHNDLGMATANSVAGIMAGAGQVEGTINGIGERAGNTSL
EEVVMAIYTQRSRYGIETGVNTREISATSRLVSRITGVPVPAHKAIVGGNAFMHASGIHQ
DGVLKERTTYEIINPEVVGVPKNRIVLSARSGRHAFRHRLEELGYYPEQENLETLYQSFL
QLADQKGEVFDQDLHALMGDSVSEGSNININNISVTTAGASRATATVTLELDGNMTTDAA
CGNGPVDAVIRAIDRLVGEPVTLEDYTLQSVSRGKEALGEATVKVRCADGVLVVGRGIST
DVIEASARAYINALVKVKRMAEGINRPAYAAIADEVSVFTNL
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
atgcgcaggctctatgtattcgatactaccctcagggatggagaacagtcacttggcata
acactaaatgttcatgagaaaattgaaatagcaaatcagctggtcaaacttggcgtggat
gtcatcgaggctggttttccggcttcatcgccgggagatttggaatcggtgcgcacgctg
gcccgggaactgaaaggtgtgatagtatgcggcctttcccgggcggtggagtatgatata
gactgctgcgccgagtcgctgcgggaggccgagtacccgaggattcacaccggtatagcg
gtatccccggtgcatatggagcaaaagctgaagctttcccccgaccaggtggtggaagct
gcggtggcggcggtaaagcatgccaaaaaatacgtgagtgacgttgaattttacgccgag
gatgcttttcgcagtgaactccccttcctggcccgggttttggagcaggttatagcagcc
ggggccacagtggtcaatataccggacacagtcggttatgccaccccctgggaatacgct
gaaatggtcaaatatgtcaaaaaccatgtcagtaatatcgataaggccgtggtgagcata
cactgtcacaacgacctgggaatggctaccgccaactctgtggcggggatcatggccggg
gcaggccaggtggagggcacaatcaacggcataggggagcgggccggcaatacctcactg
gaggaagtagtcatggccatttatacccagcgtagccgctacgggatcgaaaccggggtg
aacacccgggaaatttccgccaccagcaggctggtgtccaggattaccggcgtgccggtg
cccgcccataaggccatagtggggggcaatgcctttatgcatgcctccggcattcaccag
gacggtgtattaaaagagaggactacttatgaaataatcaacccggaagtggtgggggtg
cccaagaacaggattgttttaagcgccaggtcaggcaggcatgccttcagacacaggttg
gaggaattgggctattatccggaacaggaaaacctggagaccctgtatcaaagctttttg
caactggccgatcaaaagggggaagttttcgaccaggatttacacgctcttatgggggat
agcgtttcggaaggcagcaatattaatataaataatatttctgtaaccactgccggggct
tccagggcgaccgccacagttacccttgaactggacggtaatatgaccacggatgccgcc
tgcggcaacggaccggtggacgctgttatcagagccattgaccgtctggtgggtgagccc
gtgactctggaagattatactttacagtccgtcagccggggcaaggaggccctgggcgag
gccacggtaaaggtgcgctgtgccgatggagtactggtagtgggcaggggtatcagcact
gatgttatcgaggccagcgccagagcatacattaatgctttggttaaggtaaaaagaatg
gctgaaggaatcaacaggccggcctatgccgccattgctgatgaagtttcagtgtttact
aacctctga
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