Drosophila grimshawi: 6562499 Help Entry 6562499           CDS       T01061                                  Name (RefSeq) protein purity of essence   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism dgr  Drosophila grimshawi Brite KEGG Orthology (KO) [BR:dgr00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:dgr04121]     6562499 Enzymes [BR:dgr01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      6562499 Ubiquitin system [BR:dgr04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     6562499 BRITE hierarchy SSDB OrthologParalogGFIT Other DBs NCBI-GeneID:  6562499 NCBI-ProteinID:  XP_001989237 UniProt:  B4JC01 LinkDB All DBs Position Unknown AA seq 5382 aa AA seqDB search MSAHSGGTDWNSVVKPLLSNRTSALNKNEISNLLKAITRCEHEFFDDESNYTQFYTAFAA LAADKLMQIKSICQTQISQLHDASAVLIRFILFRLPKVSVYDIKWLLVALKMLCEGRESV ANGTGCTQFDYNTVAAVLKSAKHPESSSKSLSSSSSSAGSSGVGTDKDSPKSEIKRSRSD LSTVILQQLLAPLEPGKMTWVPLSEEISDCTEQLLAANVEYFQEQNGVDTLLDVGVGLPI LNRYRSKYLETIVGGKALYLPLTQVEASTVKSAMAHMLTDLSILGQAHSLIALQPLTPSR IEKLSMCGISALYNAVLTSIAASVLSMCQVSSGSQKQQQQQPSGVASTSQGTGSITGGNS NVPASSKDHDDFEEQACTIVNKALEIYTSIGDMFKASARMHVYQNHLCYGSWLLISGIQG AMGASGSSAATAKPTSTATTTSTTNANEATAAPSTPIARVNLFKVQQGFGELNAAIANHS IKLLSELIDDLKIETACNNSCTSGNNNCLDVEPAQFDILENYSALQRIVRVLNTATLHQL FTFLATVAYRKACTLKRANTKDRTECEPISYSDSTTYFNDSLSCSDNSEEDDSESYLGHW FKETLSPETHDDNANTCTQERNGDQKSALVPKLDEPHEYLDLAADIFCFLDQFLANRHAY MQRYVKAGVSDQQMLLMANIIKDFDRDVMRQEGGNAGSASSGGSGDCSCSNWQSAMIRFS GAAGRYIHNLISTSLLSEQLQSNLLQHLSISPWSTDTNSWPLQVYPSTLSVLVQILLLKP TQEKEAACLSVWHRLINTLVEGVCSSSTASDADFEDLNIEHAQLLLFLFHSLNLMQKKSI LLLTAGGVIRCADVCRGISADRTVRNSQMMLLSRLLLFLEYLMKHLYNAPPELLDQVRWN LFSVSSMPDTQKITDLLNSRTKLGCFCRQDIELKFRNSPVGDLNSSIRPTFYSLVTADPM KPQWAQDFKLDGLAWNFILCTPDKLKYPLLVDALIDILAITDMSALCRDKDNLHNLCAMQ YCFSITWKLLLGLPPSTSHVESLKVDRAPNLHSLLWSIRCPLASSHYLVVNSLIKQGMYT QYAETLWAQVGDRTADVRYSLKQTMLGVEAFNKQLNKASPNPRLSDLILFDALVAHMQAV AWADKEGYKLLRKESDTDSITSESRERENSSAATDPEVYSSSESIDDQQTKQSEDSTLTP GELLERTQLSNELLIKLMDSYSLISNIVRAQMLKQLSSSTPEQALNLIVPVVSDKPAIMV ELHAAFLKLLPNEDKQLIANEWPKCLLVNDDAFNGKQHPVEPYTLSVIDAHITELTKSTT YSTLHTLKHCLKSILNLLELLLPFCTSISDVELQLKPLLIASMMDMRTDYLQSQSEQCLR EILHGLTNEAHKQLLFEHMIEHCYHMLIDFAGELKQTTTTTTSTGIATVAVAPDQEQRAL FNESMLFAVLKTMIKMLDVPTAVQAMRQFFKEQRAGSLTTLLLSFTGTTLPLSYARKMLQ FVERLFEQSAQPDAQFQHEELVDCFSELAIVDVARLKLWLAHIIYGPNVVATNNSSCEAS CKLLTSIMQPSSSSSSNAQTPTNMATVSAMPSISDQLDAMDIDYDCAGAGAGNANATNAA AKCLSLWQGNNQANNQSEDSSQACDQPSASSHPRNGALLLSFVKSLVREQPAAAQLAPPL FQALLQLGQTLITPPQDGCDFADVLQIMITLADAAPARGHVALFNTTLLWLELAKLQLPY KQLRHAENVSALLRYLSELLQAIGYRGSRQHMPPWDDELQSDIDELYDELQDEQQQEQDS LLDDSDEDTLNNKLCTFSQTQKEFMNQHWYHCHTCNMINTVGVCSVCARVCHKGHDVSYA KYGNFFCDCGAKEDGSCQALSRRLPTNGCDSRDGYVSAHMSLLAAGSKKRQSPPNTQLRK DSLSNERIALLGKLLEPHREALQHADQWQLVVRCILEYFDVLLPSIRENCTLYSIVGCHK RATVALERLHQLDQSFEVTDQLMFATLGSQEGAFENVRMNYSGDQGQTIKHLISSGVVRR VAFCCLSSPHGRRQQLAVSHEKGKVTILQLSALLKQADASKRKLTLTQLSSVPIAYTVLS LAANPCNEDCLAVCGLKECHVLTFSSSGSTNEHIVVTPQLDNGNYIKKAVWLPGSQTLLA LVTSDYVKIYDLAVDTYSPKYYYLVAVGKIRDCTFMYQEDAYYMLTFASSGYIYYQTLDE QSLAIHGDFYVTNTLELSHHHIKDVNGQVGGGGVSIYYSHALQLLFYSYASGRSFFSSLT NVNQGVKGIYHLDTSSAVSKSKEGPLQPLVQWTEVAGHPGLIYANMQTSNNPIILMLTPE LIFMQEIKAQSAKSRIMDVVGIRHSVAGTEKTTLLLLCEDGSLRIFSAQPEHTSFWLSPR VQPLGNQLYSATLLAKSGSSASVSPKSLSKPNKLPRKAAALQKQLTSNGLPVFPIDFFEH CNVLADVEFGGNDLLQIYNKQKLKTRLFSTGMFVASTRANGFTLEVLNNDPNVVMVGIRV LLGTQDTQRAPQSVSILGRTIPTPVRRARWFDIPLTRDEMLQSDKLLKVCFAKSQDPENV TLLDCIEVYGKSKELVGWPDDSEELPTSANVANAATATVSPASAANFGEGFNSITQLDRM CTHLLEVLDCALNLLGNGGAVAAAMRQKAVKTASALLLLPTPNPVQTQARYVLATMYGSR GAYHSYKDSVLLQFVHGELQAMQPKLTQLDTLQDIDPEAFYRLILLVRGIANARPQSLAK ICAECNYDIVPALMAMVLELHKVTPALDEPTNIVRRGLCQTETIVHCLVEIMYGFALADA SQVGRMTKYFIELLKHDASVISHSAKEALILLLSPRIKRHKVAIVTTPPACSTPTPSTSA INTSNLSALQGAASQAASDIIEEAAAAAVDAAAAGVGVGAGGADALLEAEAGVNQAQQQL LNLEAFMGGGFPRLLGLPEDADDEAIMDIAIALSLQQHSGDANALQSLQQGLANLQGIRM AAAATANNAAVSGGDATGSDDDEGSNVATDGSTLRTSPAEQAGSGGSESGGSGVESIGGT SARSSNFGDHANASPPRQSKDQEQEQEQPGTSSSCVAALSAMSSTEDIEINEDEKLSKLH DLRIAVLESIIAHLDTFDLCNGLQAIPLIQVILMLTTDLNGNNERDQEVLQELLAALVEY VEIGQRGAAARMENKCPINEVRLALLSLFGVMMGKTKSKQTGTTSPPHQFKDNSSFVAST TANVLSKCGAFVYALESLNMLLVHWKQVLGDPYAAGGTGGVQPSNVAGNGTADQLLKPIK HGPKPDISILIPHNYLKNYPDIFESYDGLLTEIIVRLPYQILRLSSAHPDNYDSGFCEAM TFTLCEYMMLNLNALLRRQVRKLLMYICGSKEKFRMYRDGHSLDAHFRVVKRVCSIVSTK SGAPYNSNPPMLSYDALVELTEHLRTCQEISQMRTGNWQKFCVVHEDALAMLMEIACYQL DDGVSPIIIQLLQAAVCNLPQPISGGLKQQQQQLPQASSSSKMRSEREKSEDTDTAYYSK FDPAQCSTFVHQIFRYASDALIIRFVRIFLLENNASQLRWQAHSFMTGLFEHANERQREK LLSIFWNLWPLVPSYGRRTAQFVDLLGYLTLSTRSTTDRLPEFVSRAVEVLRQQNELLCK HPNAPIYTTLESILQVNGYYLESEPCLVCNNPEVPMANIKLPSVKSDSKYTTTTMIYKLV QCHTISKLIVRIADLKRSKMVRTINVYYNNRSVQAVVELKNRPALWHKARTVSLQSGQTE LKIDFPLPITACNLMIEFADFYETVSGSSENLQCPRCSAAVPAYPGVCGNCGENVFQCHK CRAINYDEKDPFLCHSCGFCKYAKFDFSMYARVCCAVDPIESAEDRAKTVQLIHSSLERA DRIYRQLLTNKQMLELLIQKVAEHRSSDRLVEDNMGSVHSTSQVNKIIQLLAQKYCVESR TSFEELSKIVQKVKACRSELVAYDRQQQDQPAVSSSGSGAESSLTTNRCYGCALASTEQC LTLLRAMAYNYDCRVGLYSQGLVSELAEHNLRRGTPQIQEEVRNLLVVLTKDNAEACMHL LQLVTTRVKNALMGAIPLISLEAAVHQEMMLLEVLLGQDDVCWEFKLKVIFELFISNCRL PRGPVTSVLHPCLRIMQNLMSPALPANKNNNLQQQQQSQSQQQQQQSQPQSAQQQQQQQQ QQQPLGPTELYSVKLVEGNTIDYRAWLNSDRNHEYSAWSSRMPTNKYQRQDGGKQRNSNS SGKQQQSGDVPAKGGRRGDVHSTYLAEKYGLRWRHLVLDKERVIKPLVFNAKWIQPLLFN ANSRFGRQLACSLLSGLCRTSERKQQALNMLTDFLRHVGEAGEASAEFLTLYRSVATETP WLQYLVLRGVLGEISQLLAVEIGKIHRMEEHSLSSDLSLGYALRQYVELLWLFLECPNIR RTYKTRLLGPVLQSYLALRSLVVQRTRLIDDAQEKLLEMLEEMTSGTEEETRAFMEILID TVEKTRMNDIKTPVFIFERLYSIIHPEEHDESEFYMTLEKDPQQEDFLQGRMLGNPYPSS EVGLGPLMRDVKNKICTDCELIALLEDDNGMELLVNNKIISLDLPVKDVYKKVWLAEGGD RDAMRIVYRMRGLLGDATEEFVETLNNKSQEQVDTEQLYRMANVLADCNGLRVMLERIGS LQRISRQRELIQVLLKLFLICVKVRRCQEVLCRPEIGAINTLLKVLQMCLQSENDSIQSA VTEQLLEIMETILSKAASDTLDSFLQFSLTFGGPEYVSALISCTDCPNVRNNPSVLRHLI RVLAALVYGNEVKMALLCEHFKHTLDFDRFDNERTTEEEFKLELFCVLTNQIEHNCIGGT LKDYIVSLGIVERALTYITEHAPCVKPTLLRTDSDELKEFISRPSLKYILRFLTGLANYH EATQLAISKDIIPIIHRLEQVSSDEHVGSLAENLLEALSTDAATASRVQQVRDFTRAEKK RLAMATREKQLDALGMRTNEKGQVTAKGSILQKIEKLRDETGLTCFICREGYACQPEKVL GIYTFTKRCNVEEFELKSRKTIGYTTVTHFNVVHVECHTSAIRLTRGRDEWERASLQNAN TRCNGLLPLWGPAVGEAAFSGCMTRHSSYMQESTQRCDISYTSSVHDLKLLLVRFAWERS FHDDAGGGGPQSNMHFVPYLLFYAVYLLLSSRSAARDSKTLLNYLTAAPSDKWLECGYEV DGPLYMLTISLSLHSRELWNKHKLAHLKRLLAVAQARHVSPSVLCKALLSPADRQTKEYG VYKPFLMMWSLVDLIYNSLFKTVSTPKEEDWPASLFEFIRKNDEVMLKSTDNILQTLTDE FLPCTSFAEFCDVAGLLNQIEQPDSFIDDVLAALPSTTSSSS NT seq 16149 nt NT seq  +upstreamnt  +downstreamnt atgtcggcgcacagcggaggtacggattggaactcggttgtaaaaccacttttatccaat cgtacaagtgctttaaacaaaaatgaaatatcaaatttactaaaagcgattaccagatgt gaacatgaattttttgatgatgaaagcaattatacacaattttatactgcatttgcggct ctggctgccgataagctcatgcaaatcaagtcaatctgtcagacgcaaatttcacaattg cacgatgcgagtgcggtgctcatacggtttatactattccgtttgccgaaagtctcagtg tatgacatcaaatggctgctggtcgcactcaaaatgttgtgcgagggtcgcgagagtgtc gccaatggtacgggttgcacccaattcgattacaataccgttgcagcggtgctgaagagc gccaagcatcccgaatcgagcagtaagagcctgagtagcagcagcagcagtgccggcagc agtggcgtcggcaccgacaaagactcgcccaaatcggagataaaacgttcgcgttccgat ctatcaacggtcatattgcaacagttactggctcccctagagccaggcaaaatgacatgg gtgccattgagcgaggagattagtgattgcaccgagcaactgcttgcggccaatgtggag tactttcaggagcagaacggcgtcgatacgctgctcgatgtgggcgttggtttgcccata ctgaatcgttatcgctccaaatatctggagacaattgtgggtggcaaggcgttgtatttg ccactcactcaagtagaggctagcactgttaaatcggcaatggcacacatgttaaccgat ttgtccattttggggcaggcacattcactgattgccctgcaacccttgacaccgagtcgc atcgagaagctatcgatgtgcggcatttcggcactatacaatgcggtgctgacttccata gcggccagtgtgctgagcatgtgccaggtcagcagtggctcgcagaagcagcaacaacag cagccgtcaggtgtggcatcaactagtcagggcacaggcagcatcaccggcggcaacagt aatgtgccagcaagcagcaaagatcatgatgatttcgaggagcaagcgtgcactattgtg aataaggcgttggagatctatacgagcattggggatatgtttaaggcctctgcacgtatg catgtctatcagaatcatttgtgctacggctcttggctgctcatcagtggcatacagggt gccatgggtgcctctggcagcagtgcagcaactgctaagccaacgtcaactgcaacaaca acatcgacgacgaatgcaaatgaggcaacagccgcccccagcacacccatagcgcgtgtt aatctcttcaaggtacaacagggcttcggggagttgaatgcagcaattgctaatcacagc attaagctgctgtcggagctcatcgatgatctaaaaattgaaacagcctgcaacaacagc tgcacaagtggcaataataattgcctggacgtcgaaccggctcaatttgatatactggag aattatagtgcattgcagcggattgttcgtgtcctgaatacggcgacactgcatcaattg ttcacgttcctggcaactgtggcctatcgcaaggcgtgcactctgaaacgtgccaatacc aaagatcgcaccgaatgcgaaccgattagttactcggattcgacaacctatttcaatgat tcactctcctgctccgacaattccgaggaggatgacagtgaaagctatttgggtcactgg ttcaaggagaccctctcccccgaaacgcacgatgataatgccaacacatgcacccaggag cgcaatggcgatcagaaatcggcacttgtcccgaaactggatgaaccgcatgaatatttg gacttggcagcggatatattttgtttcctcgatcaattcttggccaatcgtcatgcgtat atgcagcgctatgtgaaagcgggtgtcagtgatcagcagatgctgctcatggccaacata attaaggattttgatcgtgacgtgatgcgccaggaaggtggcaacgccggctccgcctct agtggtggctccggtgattgcagctgctccaattggcaatcggcaatgatacgtttctcc ggtgctgctggtcgttatatacacaacttgatctcgacatcgttgctctcggaacagcta caatcgaatctgttgcagcatttgtcaatctccccctggtcaaccgatacgaacagttgg ccgctgcaggtttacccgagcacattgtcggtgctcgtccaaatactgttgctgaagccc acccaggaaaaggaggctgcctgcctgtccgtttggcatcgtctcatcaatacgctcgtc gagggcgtctgctcatcatcgactgccagcgacgcggactttgaggatctaaacattgag catgcccaattgctgctgttcctcttccactcgttgaatctgatgcaaaaaaaatcgata ctgctgttgacggctggcggtgtcattcgctgtgccgatgtctgtcgcggcatcagtgct gatcgcactgtccgcaacagccaaatgatgctgctatcgcgtctccttctcttcctggag tatctaatgaagcatttgtataatgcaccgcccgagctgctcgatcaggtgcgctggaat ctgttcagtgtcagcagcatgcccgatacgcaaaagatcacagatctattgaacagtcgc accaaactcggctgcttctgtcgccaggacattgagcttaagtttcgcaattccccagtc ggtgacttgaactcgagcattcgacccactttctattcgctggtcactgcggatccgatg aagccgcaatgggctcaggatttcaaattggatggtttggcatggaatttcatattgtgc acgccggacaagctcaagtatccgttgctagtggatgcactcatcgatatattggccatt acggatatgtcggctctgtgccgcgacaaggacaatctgcacaatttatgcgccatgcaa tattgttttagcattacgtggaagctgttgcttgggttgccgccatccacatcacatgtg gagtccttgaaagtggatcgtgcacccaatctgcactctttgctgtggagcattcgctgt ccattggccagctcgcattacctggttgttaatagtctcatcaagcagggcatgtacacc caatacgcggagacgctctgggctcaggtcggcgatcgtacggccgatgtgcgctacagt ctcaagcagacaatgctgggcgtcgaggcgttcaacaagcaactgaacaaagcttcacca aatccacgtctgtccgatctaatcctattcgatgcgctggttgctcacatgcaggccgtg gcctgggccgataaggagggctacaagctgctgcgtaaggagagcgacacagacagcatc acttccgagagtcgggagcgtgagaactccagtgcagccacagatcccgaggtgtattcc tccagcgaatcgattgatgatcagcaaaccaaacaatcggaggacagcacattgacgccg ggggagttgctcgagcgcacacagcttagcaatgagctgctgatcaaactcatggactca tacagcctcatctcgaatattgtgcgcgcccagatgctgaagcagttgtccagttcgacg ccggaacaggcgctcaacctgattgtgcctgtggtgagcgataagccggcaattatggtt gagttgcatgcagctttcctcaaactgctgcccaacgaggataagcagctgattgcgaac gagtggcccaaatgtctgctggtcaacgatgatgccttcaacgggaaacaacatcccgtc gagccgtacacgctgagcgtcatcgatgcccacatcaccgaattgaccaaatcaacgacc tattcaacgctgcacacgctgaagcattgcctgaaatccatattaaatctgctggaacta ttgctgccgttctgcacatccatatcggatgtggagttacagctgaagccgctgcttatc gcctccatgatggacatgcgcaccgattatctgcagagccagagtgagcagtgcctccgt gaaatactccacggcttgacgaacgaggcccacaagcagctgctctttgagcacatgatt gagcattgttatcacatgctgattgattttgccggagagttaaaacaaaccacaacaaca acaacatcaactggcattgctactgttgctgttgcacccgatcaggagcaacgtgctctc ttcaatgaatccatgctgtttgctgtgctcaagacaatgattaaaatgttggatgtgcca acagctgtgcaggcgatgcgacaattcttcaaggagcaacgtgcgggcagcttaacaacg ttgttgctttcgtttacggggacaacgctgccgctgagctatgcccgcaaaatgttgcaa tttgtggagcgtctgttcgagcaatctgcccagcccgatgcacagtttcagcatgaggag ctggtcgattgtttttcggagctggccatcgtggatgtggcacgtttaaaactttggctg gcgcacattatctacggtccgaatgtggttgccacaaataatagtagctgtgaagcttcg tgcaaactgctcaccagcattatgcagccgtcgagcagctccagcagtaatgcacagaca ccaacgaacatggccactgtctctgctatgccgagtatatcggatcaattagatgccatg gatattgattatgattgtgcgggcgctggtgctggcaatgccaatgcaacgaatgcagcc gccaaatgtttgagtctgtggcagggcaacaatcaggccaacaatcaatcggaggattct tcgcaggcctgcgatcagcccagcgccagttcgcatccacgcaatggcgccttgctgctc agctttgtcaagtcgctggtgcgtgagcagccggcagcggcacagctggcaccgccactc ttccaggccctgttgcagctgggccagacgctgataacgccgccacaggatggctgtgat tttgcggatgtgttgcagataatgataacgctggcggatgcggccccggcacgtggtcac gtggcgttgttcaatacaacactgctgtggctggagttggccaagctgcagttgccgtac aagcagctgcgacacgccgaaaatgtgagcgccctgctccggtatctcagcgagctgctg caggccatcggttatcggggcagtcgacaacatatgccgccctgggatgatgagctgcag tcggacatcgacgagctgtacgatgagctgcaggatgagcagcagcaggagcaggactca ttgctcgatgactccgatgaggatacgctgaacaacaagctgtgcaccttctcgcagacc caaaaggagttcatgaatcagcattggtatcactgtcacacctgcaacatgatcaacacc gtcggcgtttgttccgtctgcgcccgcgtctgtcacaagggacacgacgtcagctatgcc aagtatggcaatttcttttgcgattgcggcgccaaagaggatggctcctgccaagcgctg agccgccgtctgcccaccaacggttgcgattcacgggacggctatgtctcggctcatatg agtctgctggccgctggcagcaagaagcgtcagtcgccgccaaacacacagctgcgcaag gattcgctgagcaatgaacgcattgcgttgctcggcaaactgctcgagccgcatcgtgag gcactgcagcatgcagaccaatggcagctcgtcgttcgctgcattctcgagtatttcgat gtgttgttgccgtcgatacgcgaaaactgcaccctctactcgattgtgggatgtcacaag cgtgccaccgtcgcgctggagcgactgcatcaactggatcagagctttgaggtgacggat cagctgatgtttgccacgcttggctcccaggagggcgcctttgagaatgtgcgcatgaac tactcgggcgatcaaggccagacaatcaagcatctaatctcgtcgggcgtggtgcgtcgc gtcgccttctgttgcctgtcatcgccgcatggcaggcgccagcagctggccgtgtcccat gagaagggcaaggtgaccatactgcagctgtcggcgctgctcaaacaggcggatgcctcc aagcgcaaactgacgttgacccagttgagttcggtgccaattgcatacactgtactctcg ctggccgcgaatccgtgcaatgaggattgcttggccgtctgtggcttgaaggagtgccat gtgctgaccttctccagcagtggcagcacaaatgaacacattgtcgtcactccccagctg gacaatggcaattacatcaagaaggctgtgtggctcccaggttcgcagacgttgctcgcc ttggtcacctcggattacgtgaagatctatgatctcgccgtggacacgtatagtccaaaa tattattatctggtggccgtgggaaagatacgtgattgcacatttatgtatcaggaggat gcatattatatgctcacctttgccagtagtgggtatatctattatcagacgctcgacgaa caaagtctggcgatacacggtgacttttatgtgacgaatacgctcgagctgagccatcat catatcaaggatgtgaatggtcaggtgggcggcggtggtgtctccatttactactcccat gcactgcagctgctgttctacagttatgcatcgggtcgcagtttcttctcgtcgctgacc aacgtgaatcagggtgtgaaaggcatttatcatctggacaccagttcggcggtgagcaaa tccaaggagggacctctccagccactagtacaatggaccgaagtcgctggccatccgggt ctaatctatgccaatatgcagacatcgaataatcccataatattgatgctgacaccggaa ttgattttcatgcaggagatcaaggcacagtcggccaagtcacgcatcatggacgtggtg ggcatacggcattcagttgccggcaccgagaagacaacgctgctgctactctgcgaggat ggcagtttgcgtatattctccgcccagccggaacacaccagtttctggctatcgccacgc gttcaaccgctgggcaatcaattgtactcggccacattgctggcgaagagtggcagcagt gcctccgtcagtcccaagtcgttgagtaagcccaacaagctgccacgcaaagcggccgca ctgcaaaaacaactgacatccaatggtctgccagtgtttcccatcgatttcttcgagcat tgcaatgtgctggcggatgtagaattcggtggcaatgatctgctccagatctataataaa caaaagctgaagacacgtctcttttccacgggcatgtttgtggcgagcacacgcgccaat ggcttcaccctggaggtgctcaacaatgatccgaatgtcgtcatggttggcatacgcgtg ctgctcggcacacaggatacgcagcgtgctccccaatccgttagcatattgggacgcaca attccaacgccagtgcgacgtgctcgctggttcgatatacccctaacccgtgacgagatg ctccagtcggataagttgctcaaggtgtgctttgccaaatcacaggatccggagaatgta acgctgctcgactgcatcgaagtgtatggcaagtcgaaggagcttgtcggttggcccgat gacagcgaggagttgcccacgtcagcaaacgtggccaatgcagccacagcaactgtttcc ccggcaagtgcagcgaatttcggtgagggtttcaatagcattacccagctggatcgcatg tgcacccatctgctcgaggtgctcgattgtgcactgaatttacttggcaatggtggcgct gtcgccgctgccatgcgccagaaggcagtgaagacggccagcgctctgctcctgctgccc acacccaatcccgtgcagacgcaggcacgttacgtgctggccacaatgtatggcagtcgt ggcgcctatcatagctacaaggatagcgttctgctgcaatttgtacatggtgaattgcag gcgatgcaaccgaaactcacccagctggacacactgcaggacatcgatccggaagcgttt tatcgtctcattttacttgtgcgtggcattgccaatgcacgtccacaatcgctggccaag atttgtgccgaatgcaattatgatattgtgccggcgctcatggccatggtgctggagctg cacaaggtgacgcccgcgttggatgagcccacaaacattgtgcgtcgcggcctgtgccag accgaaacgattgtccattgtctggtggagattatgtatggctttgccttggccgatgcc agccaagtgggccgcatgaccaagtactttattgagctgctcaagcatgacgccagcgtg attagtcatagcgccaaggaggccctcatccttctgctcagtccgcgcatcaagcggcac aaggtggccatcgtgaccacaccgcccgcatgctccacgcccaccccatccacatcggcc atcaacacgagcaatttgagtgcactccagggtgctgcttcacaggccgccagcgatatt attgaggaggctgctgcagcagcggttgatgcagccgccgctggtgttggtgttggtgcc ggtggcgctgacgcactgctcgaagcggaggcaggcgtaaatcaggcgcagcagcaactg ctgaatctggaagcgttcatgggtggcggctttccacggctgctcggcctgcccgaggat gcagatgatgaggccatcatggatattgccattgcgctcagtctgcagcagcatagcgga gatgcaaatgcactgcaatccctgcaacaaggattggccaatttacagggtatacgtatg gctgcagctgccactgctaataatgcggctgtaagtggcggcgatgcgaccggctccgat gatgatgagggatccaatgtggccacagatggctcaacgctgcgcacttcacccgctgaa caggcgggcagcggtggctccgagagcggtggcagcggtgtcgagagtattggtggcacc tccgcccgcagcagcaatttcggtgatcatgcaaatgcctcaccgccccgtcagagcaag gatcaggaacaggaacaggagcagccgggcacgagcagcagctgtgtcgctgcgctcagc gcaatgagcagcaccgaggacattgagatcaatgaggatgagaagctgagcaaactgcac gatctgagaattgccgtgctggagagcatcattgcgcatctggacacatttgatctgtgc aacggcttgcaagctatacccctgattcaggtcatactaatgctgaccaccgatctaaat ggcaacaatgaacgggatcaggaagtgctccaagaactgctcgccgctctagtcgaatat gtggagattggtcaacgtggcgcagctgccaggatggaaaacaagtgccccatcaatgag gtgcgcctggcactgctctccctgtttggcgttatgatgggcaagaccaagtcaaagcag actggcaccacatcgccaccgcatcagttcaaggacaacagctcgtttgtggccagcacc acggcgaatgtgctgagcaagtgtggcgcctttgtctatgcattggagtcgctcaacatg ctgctcgtccactggaagcaagtgcttggcgatccctacgctgctggcggcactggcggc gtccagccatccaatgtggccggcaacggaacagcagatcaactcctaaaacctatcaag catggccctaaaccggatatatcgatactgataccgcataactatttgaaaaactatccg gatatttttgaatcgtatgacggcctgctcaccgagatcattgtgcgtctaccgtatcag attttgcggctgagcagcgctcacccggacaactatgacagtggcttctgtgaggcgatg accttcaccctgtgcgagtacatgatgctcaatctgaatgcgctgctgcggcgccaggtg cgcaagctgctcatgtacatctgcggcagcaaggagaagttccgcatgtatcgtgacggg cattcactggacgcacacttccgcgtcgtcaagcgtgtctgcagcattgtcagcaccaag agcggcgctccttacaattcaaatccgccaatgctgagctacgatgcgctcgtagagctc actgagcatctgcgcacctgccaggagatcagccagatgcgcacgggcaattggcaaaag ttctgtgtggtgcacgaggatgcgttggccatgctaatggagattgcctgctatcagctg gacgatggtgtctcacccatcattatacagctgctgcaggcggctgtttgcaatttgcca cagcccatttcggggggtctcaagcagcagcagcagcaactgccgcaagcctcgtcgagc agcaaaatgcgcagcgagcgcgagaagagcgaggatacggataccgcatactactccaaa tttgatccggcacagtgcagcacatttgtgcatcagatctttcggtatgcgagcgatgcg ctcatcatacgcttcgtgcgcatctttctgctggagaacaatgccagtcagctgcgctgg caggcgcactcattcatgaccggtctcttcgagcacgccaacgaacggcaacgcgagaag ctgttgagcatcttctggaatctgtggccactggtgcccagctatggtcgtcgcaccgcc caatttgttgatctgctcggctatctaacgctgagcacgcgcagcaccaccgatcgtctg cccgagtttgtctcgcgggccgttgaagtgctgcgccagcaaaacgagctactctgcaag catcccaatgcacccatctataccacactggagtccatactgcaggttaatggctattat ctggaatcggaaccgtgtctggtgtgcaacaatccagaggtgccgatggcaaacataaag ctgccctcggtcaagtccgactcaaagtatacgacaaccacaatgatctacaagctggtg cagtgtcacaccatctccaagctaatcgtacgcattgcggatctcaagcgctccaaaatg gtgcgcactatcaatgtttactacaacaatcgcagcgtgcaagcagttgtcgaactgaag aatcgtccggcactgtggcataaggcacgcaccgtctccctgcagtcgggacagactgag ctgaagattgacttcccgcttccgattactgcatgcaatctgatgattgagttcgctgac ttctacgagacggtcagcggcagcagtgagaatttgcagtgtccacgctgcagtgcagcg gtgcccgcatatccgggcgtttgtggcaattgtggcgagaatgtgttccaatgccacaag tgccgggccatcaactacgacgaaaaggatccgttcctgtgccactcgtgcggcttctgc aaatatgccaaatttgattttagcatgtatgcacgagtttgttgcgccgtcgatcccatt gagtctgccgaggatcgggccaagactgtccagctgatacacagctcgctggagcgtgcc gatcgcatctaccgccagctgttgactaataagcaaatgctcgagctgctcatccaaaag gtggccgagcatcgcagcagcgatcgcctcgtcgaggataatatgggcagtgtgcacagc acctcgcaggtgaacaagatcatccagctgctcgcccagaagtactgcgtcgaatcgcgc accagcttcgaggaactcagcaagattgtgcaaaaagtcaaggcatgccgcagtgaactg gttgcctacgatcgtcagcagcaggatcagccggcagtttcgagctcaggttcgggcgct gagtcaagtctgaccacaaatcgttgctatggctgcgccttggcctccaccgaacagtgt ctgacgctgttgcgtgccatggcctataactatgattgtcgcgttggcctctacagtcag ggcctggtcagcgagctggccgagcacaatttgcgacgtggcacaccccaaatccaggag gaggtgcgcaatcttctggtggtcctgaccaaggacaatgccgaggcctgcatgcatctg ctgcaactggtgacgacccgtgtcaagaatgcgcttatgggcgccatacccctaatcagt ctggaggcggctgtgcatcaggagatgatgctgctcgaagtgttgctcggtcaggatgat gtctgctgggagttcaagctgaaggtcatctttgaactgtttatcagcaattgtcgtttg ccacgtggtccggttacatcggtgctgcatccttgtctgcgcatcatgcagaatctcatg agtcctgcactgccagctaacaaaaataacaatctacaacagcagcagcagtcgcaatcg cagcagcagcagcaacaatcgcaaccacaatcagcgcagcagcagcagcagcaacagcag cagcagcagccattgggtccgacggaattgtacagcgtgaagctggtcgaggggaatacc atcgactatcgcgcctggctcaactcggatcgtaatcacgagtacagcgcttggagcagt cgcatgcccaccaataaatatcagcgtcaggatggcggcaaacaacgcaacagcaacagc agtggcaagcaacagcaatctggcgatgtgcccgccaagggtggacggcgtggagatgtg cactccacatatttggccgagaagtatggtctgcgctggcgtcatctggtgttggacaag gagagggtgattaagccgctggtgttcaatgccaaatggatacagcccttgctgttcaat gccaactcgagatttggacgccaattggcgtgctcgctgctcagtggcctgtgccgcacc agcgaaaggaagcagcaagcgctcaacatgctcaccgacttcctgcgccatgtgggcgag gcgggtgaggcgagtgccgagttcctgaccctctacaggagtgtggccacagagacgcct tggctgcaatatctggtgttgcgtggtgtgctcggcgagatctcgcaactgttggctgtg gaaattggtaaaattcatcgcatggaggagcattcattgtcctcggatctatcgctcggc tatgcgttgcgtcaatatgtggaattgctgtggctattcctcgagtgccccaacatacga cgcacgtacaagacacgtctcctgggacccgtcctgcagagctatctggcgttgcgtagc ctggtcgtgcagcgcacccgtctcatcgatgatgcgcaggagaagctgctcgaaatgctc gaggagatgaccagcggcaccgaggaggagacgcgtgcctttatggagattctcatcgat accgtggagaagacgcgcatgaatgacattaagacacctgtcttcatatttgagcgcctg tactccatcattcatccggaggagcatgatgagagcgagttctatatgacgctggagaag gatccgcagcaggaggacttcctgcagggtcgcatgctcggcaatccgtatccctccagc gaggtgggactcggtcccctaatgcgcgatgtgaagaacaaaatctgcacagactgtgaa ctgattgcactgctcgaggatgacaatggcatggaactgctggtgaacaataagattatc agtctggatctgcccgtcaaggatgtgtacaagaaggtgtggctagccgaaggtggcgat cgagatgccatgcgcattgtgtatcgcatgcgcggtttgctgggcgatgccaccgaggag tttgtggagacgctgaacaacaagagccaggagcaggtcgatacggagcaactgtatcgc atggccaatgtcctggccgattgcaatggactgcgtgtgatgctcgaacggattggcagc ctgcagcgcatctcgcgacagcgtgaactcatccaagtgctgctcaagctgttcctcatc tgtgtgaaggtgcgtcgctgccaagaagtgctctgccgccccgaaattggcgccatcaat acgctgctcaaggtgctgcagatgtgcctgcaatccgagaacgattccatacaatcggcc gtcaccgagcagctgctcgagattatggagaccatactctcgaaggcggccagcgacacc ctcgactcgttcttgcagttctcgttgaccttcggtggtcccgaatatgtcagcgctctg atctcgtgcaccgattgccccaatgtgcgcaacaatccatctgtgctgcgtcatctcatt cgtgtccttgccgcgctcgtctacggcaacgaagtcaaaatggcgctgctctgtgaacac tttaagcacaccctggactttgatcgctttgacaatgagcgcaccaccgaggaggaattc aagttggaactgttctgtgtgctaaccaatcaaattgagcacaattgcattggtggcaca ctcaaggattacattgtcagcctgggcattgtggagcgcgcacttacctatataacggag catgcgccgtgcgtgaaaccgacactcctccgcaccgactccgatgaactgaaggagttc atttcgcgaccgagcttgaagtacattttgcgcttcctcaccggtttggccaattatcat gaggccacccagctggccattagcaaggatataataccgattatacacaggctggagcag gtatccagcgatgagcatgtcggcagtctggccgagaatctgctcgaggcactcagcaca gatgcggcgacagcatctcgggtccagcaggtgcgcgactttacgcgcgccgaaaagaaa cgcctggcgatggcgacgcgtgagaagcaactggacgcactgggcatgcgcaccaacgag aagggacaagtgacagccaagggctccatactgcaaaagatcgagaaactgcgcgacgag acgggcctcacctgtttcatttgccgcgagggctacgcctgccaaccggagaaggtgctc ggcatctatacgttcaccaagcgctgcaatgtcgaggaatttgagttgaagtcacgcaaa acgattggctacaccaccgtcacccactttaatgtggtgcacgtcgaatgtcacacatcc gccatacgcctgacgcgtggtcgcgacgaatgggaacgcgccagcctgcagaacgcgaat acccgttgcaatggtctcttacccctctggggccccgctgttggtgaggctgccttctcc ggctgcatgacccgacacagcagctacatgcaggagagcactcagcgctgcgacatctcg tatacgagcagtgtgcacgatctgaaactgttgctggttcgtttcgcctgggagcgtagc ttccacgatgatgccggcggcggtggtccacaatccaatatgcactttgtgccctacctg ctcttctatgcggtctatttgctgctctcgtcacgctccgccgcacgggatagcaaaaca ctgctcaactatctgacggcagcgccgtcggacaaatggctcgaatgtggctacgaggtg gatggaccactgtacatgctaaccatatcgctgtcgctgcacagtcgcgagctgtggaac aagcataagttggcgcatttgaagcgtctgctggcggtggcacaggcgcgtcacgtctcc ccctcggtgctgtgcaaggcgctgctgtctccggcggatcgtcagaccaaggagtatggc gtttataagccgttccttatgatgtggtcactggtcgatttgatctacaattcgctgttc aagacggtcagcacgcccaaggaggaggattggccagcttcactatttgaatttatacgc aagaatgatgaggtgatgctcaagtcgacggataacatcctgcaaacgttgaccgatgag tttttgccgtgcacctcattcgccgagttctgcgatgtggctggcttgctaaatcagatc gagcaaccggatagcttcattgacgacgtactcgccgcgttgcccagcactacatcaagc tctagttaa

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