Desulfurispirillum indicum: Selin_0427
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Entry
Selin_0427 CDS
T01383
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
din
Desulfurispirillum indicum
Pathway
din00300
Lysine biosynthesis
din00550
Peptidoglycan biosynthesis
din01100
Metabolic pathways
din01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
din00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Selin_0427
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Selin_0427
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Selin_0427
Enzymes [BR:
din01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Selin_0427
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADU65180
UniProt:
E6W054
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Position
448548..449885
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AA seq
445 aa
AA seq
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MKKICSWAQLAALHPEATLLGEPGATFAGFAIDSRRVQSGELFIALATASDDGHAYIADA
CRKGAAGALVHQLPADHQQLIDAGHALLVVPDTLAALAILAANWRQQWEFPVVAVTGSSG
KTTVSACLRTLFPTSAGTTGNYNNHIGLPLSMLGTPADAAIGVFELGMSGSGEIDALAEL
LQPQIGLITNVGSAHIGKLGSFAAILEAKLELARHCSCLIVDGDGQELLDRARQRHQDVL
SVGFTAGCQVFPQSMELRGEGGYHLEIRHPWSHGLLSLTVPFGQKFMVKNSLLAIAAGLK
LGLDQAALQAGLRRVQLPPLRWELHRRGGNTYIFDCYNSNPGSLRAALEDFSHYPGYRVA
VLGEMRELGAFSEREHRKVASAINCDLVLTYGDEARFLADELGADIATHCPTLEDVVARL
ANCQNAVVLVKGSRGNQMERLLDAL
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
gtgaagaaaatatgttcatgggcgcagctggctgcccttcaccccgaggcgaccctgctg
ggtgagcctggcgcgaccttcgccggctttgccatcgacagccgccgggttcagtcaggg
gaactcttcatcgcgctggcaacagcaagcgatgacggtcacgcctatattgccgatgcc
tgccgcaagggtgcagccggcgccctggtgcatcagctgcccgcagatcaccagcagctc
atcgacgcgggccatgccctgctggtggttcccgataccctggcggcactggcaattctg
gcggccaactggcggcagcagtgggaatttcccgtggtggcggtgactggcagctctggc
aaaaccacggtcagtgcctgtctgcgcactctttttccgacaagtgccggtacaacgggc
aactacaataaccatatcggtctgccgctctccatgttggggacgcctgctgatgccgcc
ataggtgtttttgagctgggcatgagcggttccggggagatagacgctctggctgaactg
ctgcaaccgcagatcggcctgattaccaatgtcggttcggcccacatagggaaactgggg
agtttcgctgctattctggaggccaagctggagctggcacgccactgctcctgcctgatt
gttgacggtgatggccaggaactgctggatagggcgcgccagcgacaccaggatgtgctc
agcgtgggtttcacagcgggctgccaggtttttccccagtccatggagctccgtggtgaa
ggcggataccatctggagattcgtcacccctggagccacgggctgctgagcctgacagtg
ccttttgggcagaaattcatggtgaaaaacagtctgctggcgattgccgccgggttgaag
ctgggtcttgatcaggcggccctgcaggcggggttgcgaagggttcagttgccgcccctg
cgctgggagcttcatcgccgtgggggaaatacctatatatttgactgctataattccaat
cccggttcgttacgggcggccctggaggatttttcccactatccgggctatcgcgtggcg
gtgctgggagagatgcgcgaactgggggcgttcagcgagcgtgaacaccgcaaggtggcc
tcggcgatcaattgtgacctggtgctgacctatggtgacgaggctcgcttcctggccgat
gagctgggtgcggatattgccacccactgccccactctggaggacgttgtggcacgactt
gcgaattgccagaatgctgtggttttggtaaaaggttcccgaggaaaccaaatggaaagg
cttcttgatgctctataa
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